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Introduction About PRAISVATE S3 OINTMENT

PRAISVATE S3 OINTMENT is a combination of Clobetasol propionate and Salicylic acid which belongs to a group of medicines called Topical Corticosteroids and Keratolytic agents, respectively. PRAISVATE S3 OINTMENT is used to manage and provide relief from inflammatory manifestations of skin conditions such as psoriasis (skin condition marked by rash and itchiness), and eczema (skin inflammation) in affected individuals. PRAISVATE S3 OINTMENT is also used to provide relief from skin redness, itching, and/or swelling due to various skin conditions. It is also indicated for use to manage other skin conditions such as dermatoses (skin lesion), seborrheic dermatitis of scalp and/or ichthyosis vulgaris (inherited skin condition marked by dry & scaly skin) in affected individuals.

PRAISVATE S3 OINTMENT is generally not recommended for use in patients allergic to Clobetasol, and/or Salicylic acid. PRAISVATE S3 OINTMENT is advised to be used in pregnant and breastfeeding women only if it is clearly necessary. PRAISVATE S3 OINTMENT is not recommended for use in children and adolescents (aged below 12 years). The medicine is advised to be used with caution in elderly patients (aged above 65 years) after consulting the doctor.

The most common side-effects associated with the use of PRAISVATE S3 OINTMENT are irritation, burning, redness, and/or stinging sensation (at the site of application), skin rash, itching, and/or peeling/ thinning of skin. Consult your doctor if any of these side effects worsens.

Uses Of PRAISVATE S3 OINTMENT

It is used to:

manage and provide relief from inflammatory manifestations of skin conditions such as psoriasis and eczema
provide relief from skin redness, itching, and/or swelling due to various skin conditions
manage other skin conditions such as dermatoses, seborrheic dermatitis of scalp, and/or ichthyosis vulgaris in affected individuals

How PRAISVATE S3 OINTMENT Works

PRAISVATE S3 OINTMENT provides relief from psoriasis and eczema, where Clobetasol propionate manages inflammation by blocking the production of certain chemical messengers (prostaglandins) that make the skin red, swollen, and/or itchy. Salicylic acid softens the skin by removing dead skin cells and breaking down keratin clumps which results in reducing itchiness and redness of skin, thus providing relief from psoriasis and eczema in affected individuals.

How to use PRAISVATE S3 OINTMENT

Always apply PRAISVATE S3 OINTMENT as directed by your physician. It is for external use only. Wash your hands and apply a thin layer of medicine on the affected area. Avoid covering the affected area with airtight dressings unless recommended. Avoid applying the medicine on face, groin, or axillae. Your doctor will decide the correct dose. and duration for you depending upon your age, body weight and disease condition.

Side Effects Of PRAISVATE S3 OINTMENT

Common

irritation, burning, redness, and/or stinging sensation at the site of application
peeling/thinning of skin

Uncommon

erythema (skin redness)
telangiectasia (condition marked by small, widened blood vessels on the skin)

Stop applying PRAISVATE S3 OINTMENT and contact your doctor immediately if you experience any of the following side effects:

blurred vision, dizziness, fainting, and/or irregular heartbeat
irritation, and/or sensitization

How To Manage Side Effects

Skin rash Or Itching

Try to pat/tap your skin instead of scratching it. Hold a damp towel to cool your skin. Wear loose clothing and avoid tight clothes, or clothes made from wool or synthetic fabrics. Avoid using perfumed soaps, deodorants, and/or moisturizers and use a skin softener regularly. Consult your doctor if the symptom does not improve or gets worse.

Warning & Precautions

Pregnancy

Monitoring required

PRAISVATE S3 OINTMENT should be used with caution in pregnant women only if it is clearly necessary. Consult your doctor before applying the medicine.

Breastfeeding

Monitoring required

PRAISVATE S3 OINTMENT should be used with caution in breastfeeding women only if it is clearly necessary. Consult your doctor before applying the medicine.

Allergy

Contraindicated

Do not use PRAISVATE S3 OINTMENT if you are allergic to Clobetasol, Salicylic acid, and/or any other ingredients of this medicine.

Use In Pediatrics

Contraindicated

PRAISVATE S3 OINTMENT is not recommended for use in children and adolescents (aged below 12 years). Consult your doctor before using the medicine.

Use In Geriatrics

Use with Caution

PRAISVATE S3 OINTMENT should be used with caution in elderly patients (over 65 years of age). Consult your doctor before using the medicine.

Interactions

A. Drug-Drug interactions:

Inform your doctor if you are taking any ayurvedic, homeopathic, and/or any other medicines before using PRAISVATE S3 OINTMENT.

Overdosage:

If you or anyone else applies too much of PRAISVATE S3 OINTMENT or accidentally swallows it, consult your doctor immediately or visit the nearby hospital to manage overdose symptoms.

Synopsis

Drug	:	Clobetasol propionate, Salicylic acid
Pharmacological Category	:	Topical Corticosteroids, Keratolytic agent
Therapeutic Indication	:	Psoriasis, Eczema, Other skin conditions (such as dermatoses, seborrheic dermatitis of scalp, and/or ichthyosis vulgaris)
Dosage Forms	:	Cream, Lotion, Ointment

More Information

Storage

Keep PRAISVATE S3 OINTMENT out of reach of children
Store PRAISVATE S3 OINTMENT below 30°C

FAQs About PRAISVATE S3 OINTMENT

Q: What is PRAISVATE S3 OINTMENT used for?

A: PRAISVATE S3 OINTMENT is used to manage and provide relief from inflammatory manifestations of skin conditions such as psoriasis and eczema. It is also used to provide relief from skin redness, itching, and/or swelling which is also indicated for use to manage other skin conditions such as dermatoses, seborrheic dermatitis of scalp, and/or ichthyosis vulgaris in affected individuals.

Q: What are the side effects of PRAISVATE S3 OINTMENT?

A: The most common side-effects associated with the use of PRAISVATE S3 OINTMENT are irritation, burning, redness, and/or stinging sensation (at the site of application), skin rash, itching, and/or peeling/ thinning of skin. Consult your doctor if any of these symptoms worsens.

Q: How PRAISVATE S3 OINTMENT works?

A: PRAISVATE S3 OINTMENT provides relief from psoriasis and eczema, where Clobetasol propionate manages inflammation by blocking the production of certain chemical messengers (prostaglandins) that make the skin red, swollen, and/or itchy. Salicylic acid softens the skin by removing dead skin cells and breaking down keratin clumps which results in reducing itchiness and redness of skin, thus providing relief from psoriasis and eczema in affected individuals.

Q: How PRAISVATE S3 OINTMENT is applied?

A: Always apply PRAISVATE S3 OINTMENT as directed by your physician. It is for external use only. Wash your hands and apply a thin layer of medicine on the affected area. Avoid covering the affected area with airtight dressings unless recommended. Avoid applying the medicine on face, groin, or axillae. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.

Q: Can PRAISVATE S3 OINTMENT be used in pregnant and breastfeeding women?

A: Yes, PRAISVATE S3 OINTMENT can be used but with caution in pregnant and breastfeeding women only if it is clearly necessary. Consult your doctor before applying PRAISVATE S3 OINTMENT.

References

1. KD. Tripathi. Drugs Acting on Skin and Mucous Membranes. Essentials of medical pharmacology. Seventh edition. 2013. Page-889, 889.

2. Jana Petersen, Claudia Garbe, Sandra Wolf, Brigitte Stephan, Matthias Augustin, Kristina Hagenström. Medicinal Treatment of Elderly Psoriasis Patients before and after Entering a Nursing Home. NIH National Library of Medicine. National Center for Biotechnology Information. PMC PubMed Central. [Revised in September 2022] [Accessed on 16th November 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9498407/

3. Lilit Garibyan, Albert S. Chiou, Sarina B. Elmariah. Advanced Aging Skin and Itch: Addressing an Unmet Need. NIH National Library of Medicine. National Center for Biotechnology Information. PMC PubMed Central. [Revised in June 2014] [Accessed on 16th November 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4051285/

4. Ziska Pharmaceuticals Ltd. Closalic Ointment. [Accessed on 16th November 2022] http://ziskapharma.com/uploads/products/Closalic_Insert_Size.pdf

5. Sangrose Laboratories Pvt. Ltd. Closal. [Accessed on 16th November 2022] https://sangroselaboratories.com/products/

6. Swisschem Dermacare. CLOBSOL-S. [Accessed on 16th November 2022] https://www.swisscosmed.in/product/clobetasol-salicylic-acid-3

7. Care Formulation Labs Pvt. Ltd. MYSELIC. [Accessed on 16th November 2022] https://careformulationlabs.com/product/myselic/

8. Velite. CLOBISOL-S LOTION. [Accessed on 16th November 2022] https://velite.in/index.php?route=product/product&product_id=183

9. Ederma Pharma India Pvt Ltd. ECZIVATE-S 6% LOTION. [Accessed on 16th November 2022] https://edermapharma.com/product/eczivate-s-6-lotion/

10. QndQ Derma. Comply-S. [Accessed on 16th November 2022] https://www.qndqdermacare.com/product/comply-s

11. Hanuchem Laboratories. Comply-S. [Accessed on 16th November 2022] https://www.hanuchemlabs.com/ointemnts

12. Innovative Pharmaceuticals Pvt Ltd. Clotrol-S Ointment. [Accessed on 16th November 2022] https://www.innovativepharma.in/product/clotrol-s-ointment/

Useful Diagnostic Tests

Patch test
Skin biopsy

Author Details

Written By Dr. Janet.C - Pharm.D

Reviewed For Accuracy By Dr. Karthikeyan Rajagopal - M. Pharma, Ph.D (Pharmacology)

Last updated on 07 Aug 2024 | 10:54 AM(IST)