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Introduction About DEXTROSE 5% INFUSION

DEXTROSE 5% INFUSIONcontains Dextrose which belongs to the group of medicines called Fluids and Electrolytes. It is used in adults and in children as a fluid replacement therapy to provide energy and to prevent fluid loss (dehydration) from the body. It acts as a source of calories (for energy) and water (for hydration) for our body. DEXTROSE 5% INFUSION can also be used as a diluent (liquid used for mixing) for another medications (such as heart medicines, stomach medicines, brain medicines) before administration. DEXTROSE 5% INFUSION will be administered to you only by your doctor or a nurse as a slow intravenous infusion (i.e., through veins).

Before DEXTROSE 5% INFUSION is given to you, inform your doctor if you have any liver, kidney, or heart problems. You must also inform your doctor if you have diabetes, bleeding in the brain or spine, sugar intolerance, damaged veins, or a very low urine output before receiving the medicine. During management with DEXTROSE 5% INFUSION your doctor will constantly monitor your blood sugar and electrolyte levels as a precaution.

DEXTROSE 5% INFUSION should be used in pregnant or breastfeeding women only if it is considered necessary by the physician. The most common side effect of receiving DEXTROSE 5% INFUSION is pain, irritation and swelling at the injection site. Place an ice pack on the injected site to ease the irritation. If the symptom did not improve, inform your doctor.

Uses Of DEXTROSE 5% INFUSION

It is used in adults and children to:

Manage dehydration (fluid loss from the body)
Provide energy and to restore fluid balance in the body
Dilute other compatible medicines prior to administration (diluent)

How DEXTROSE 5% INFUSION Works

DEXTROSE 5% INFUSION contains simple sugars that provides energy to your body. Following administration, it replaces the fluids lost from the body and supplements your body with sufficient energy.

How to use DEXTROSE 5% INFUSION

DEXTROSE 5% INFUSION will be given to you only by a doctor or a nurse into the vein as a slow intravenous infusion. Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and health condition.

Side Effects Of DEXTROSE 5% INFUSION

Common

Pain, inflammation, irritation and swelling at the site of injection
Changes in electrolyte levels
High blood sugar levels
Systemic infection or infection at the site of injection

Consult your doctor immediately if you experience any of the following side effects while receiving DEXTROSE 10%:

Formation of blood clot in the vein where the medicine is administered
Overhydration causing edema or fluid buildup in the lungs
Severe allergic reactions (such as abnormal rapid breathing, shortness of breath, low oxygen level in the blood, tightness of chest, increased heart rate, low blood pressure, bluish discoloration of the skin or nails, vomiting, nausea, headache, sweating, dizziness, altered mental activity, redness of skin rash, itchiness, fever, and chills etc.)

How To Manage Side Effects

Injection Site Reactions

Place an ice pack on the injected site. Do not move the affected area frequently. If the symptom worsens, consult your doctor.

Warning & Precautions

Pregnancy

Monitoring required

DEXTROSE 5% INFUSION should be used in pregnant women only if it is considered necessary by the physician. Therefore, inform your doctor before receiving DEXTROSE 5% INFUSION if you are pregnant or think you may be pregnant.

Breastfeeding

Use with Caution

DEXTROSE 5% INFUSION should be used with caution in breastfeeding women. Therefore, inform your doctor before receiving DEXTROSE 5% INFUSION if you are breastfeeding.

Kidney

Use with Caution

DEXTROSE 5% INFUSION should be used with caution in patients with kidney problems. Therefore, consult your doctor before receiving the medicine.

Liver

Use with Caution

DEXTROSE 5% INFUSION should be used with caution in patients with liver problems. Therefore, consult your doctor before receiving the medicine.

Allergy

Contraindicated

Do not receive DEXTROSE 5% INFUSIONif you are allergic to Dextrose.

Heart Disease

Use with Caution

DEXTROSE 5% INFUSION should be used with caution in patients with heart problems. Therefore, consult your doctor before receiving it.

Use In Pediatrics

Consult your doctor

DEXTROSE 5% INFUSION should be used in infants, children, and in adolescents (aged between 0-18 years) under careful medical supervision. Proper dose adjustments and careful monitoring are required in such patients (especially in newborns with low birth weight).

Use In Geriatrics

Use with Caution

DEXTROSE 5% INFUSION should be used with caution in the elderly patients. Therefore, consult your doctor before receiving it.

Others

DEXTROSE 5% INFUSION is not recommended for use if you:

Have bleeding in the brain or spine
Are severely dehydrated with no urine output
Are severely malnourished

Before receiving DEXTROSE 5% INFUSION inform your physician if you:

Have chronic uremia (toxin build up in the blood)
Have sugar intolerance
Have diabetes
Have vein damage or blood clot in the vein

Interactions

A. Drug-Drug interactions:

Before receiving DEXTROSE 5% INFUSIONinform your doctor if you are taking any prescription, non-prescription and over-the-counter medicines as a precaution.

Overdosage:

DEXTROSE 5% INFUSION will be administered to you only by a doctor or a nurse in a hospital, and so it is unlikely to receive an overdose. However, consult your doctor or nurse if you experience any unusual symptoms.

Synopsis

Drug	:	Dextrose
Pharmacological Category	:	Simple Sugar
Therapeutic Indication	:	Dehydration, Hypoglycemia
Dosage Forms	:	Tablet, Injection, Powder

More Information

Storage

Keep DEXTROSE 5% INFUSIONout of reach from children
Store DEXTROSE 5% INFUSIONat room temperature

FAQs About DEXTROSE 5% INFUSION

Q: What is the use of DEXTROSE 5% INFUSION?

A: DEXTROSE 5% INFUSION is used as a fluid replacement therapy to provide energy and to prevent fluid loss (dehydration) from the body. It can also be used as a diluent (liquid used for mixing) for another medications (such as heart medicines, stomach medicines, brain medicines) before administration.

Q: Is DEXTROSE 5% INFUSION safe?

A: DEXTROSE 5% INFUSION is safe when used under proper medical supervision and at the prescribed doses.

Q: What DEXTROSE 5% INFUSION does to my body?

A: DEXTROSE 5% INFUSION contains simple sugars that provides energy to your body. Following administration, it replaces the fluids lost from the body and supplements your body with sufficient energy.

Q: What precautions do I need to follow while taking DEXTROSE 5% INFUSION?

A: Before DEXTROSE 5% INFUSION is given to you, inform your doctor if you have any liver, kidney, or heart problems. You must also inform your doctor if you have diabetes, bleeding in the brain or spine, sugar intolerance, damaged veins, or a very low urine output before receiving DEXTROSE 5% INFUSION. Talk to your doctor before receiving DEXTROSE 5% INFUSION if you are pregnant or think you may be pregnant.

Q: How DEXTROSE 5% INFUSION is administered?

A: DEXTROSE 5% INFUSION will be given to you only by a doctor or a nurse into the vein as a slow intravenous infusion. Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and health condition.

Q: Is DEXTROSE 5% INFUSION safe for use during pregnancy?

A: DEXTROSE 5% INFUSIONshould be used in pregnant women only if it is considered necessary by the physician. Therefore, inform your doctor before receiving DEXTROSE 5% INFUSIONif you are pregnant or think you may be pregnant.

Q: Why DEXTROSE 5% INFUSION is mixed with other medicines before administration?

A: It is because DEXTROSE 5% INFUSIONmay also be used as a diluent which can dilute the concentration of other medicines before administration.

References

1. Todd W. Mattox and Catherine M. Crilly. Parenteral Nutrition. Brian L. Erstad. Hypovolemic Shock. Table 31-3. Pharmacotherapy – A pathophysiologic Approach. 8th Edition. 2011. Page - 2506-2508 & 426-427.

2. Abolfazl Firouzian, Alieh Zamani Kiasari, Gholamali Godazandeh, Afshin Gholipour Baradari, Abbas Alipour, Arman Taheri, Amir Emami Zeydi, and Maryam Montazemi. The effect of intravenous dextrose administration for prevention of post-operative nausea and vomiting after laparoscopic cholecystectomy: A double-blind, randomised controlled trial. NIH. National Library of Medicine. National Center for Biotechnology Information. PMC. PubMed Central. October 2017. [Accessed on 8th September 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5664885/

3. Baxter Healthcare Corporation. Dextrose Injection. Baxter PI.com. Revised in August 2020]. [Accessed on 8th September 2022] https://www.baxterpi.com/pi-pdf/DEXTROSE_Injection_USP_in_VIAFLO_Plastic_Container.pdf

4. B. Braun Medical Inc. DEXTROSE- dextrose injection, solution. Dailymed.com. [Revised in November 2019]. [Accessed on 8th September 2022] https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=60b6d7c3-0164-46c9-aa38-b5aa1c31a5d5&type=display#LINK_b2d1c2a5-5097-43b7-a156-db93acf1782

5. Baxter Healthcare Corporation. U.S. Food and Drug Administration. [Revised in December 2014] [Accessed on 8th September 2022] https://www.accessdata.fda.gov/drugsatfda_docs/label/2014/017521s068lbl.pdf

Author Details

Written By Dr. Janet.C - Pharm.D

Reviewed For Accuracy By Dr. Narayanasetty Sai Swaroop - Pharm.D

Last updated on 23 Jul 2024 | 04:48 PM(IST)