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Introduction About SD PILL TABLET

SD PILL TABLET is a combination of Dapoxetine and Sildenafil, which belong to the group of medicines called Selective serotonin reuptake inhibitors and Phosphodiesterase type 5 (PDE5) inhibitors, respectively. It is used in adult men to help improve blood flow to the penis and to manage early ejaculation by balancing certain chemicals in the brain.

Before taking SD PILL TABLET, inform your doctor if you have any previous history of fainting or dizziness due to low blood pressure. You must also inform your doctor if you have epilepsy, lung problems, mental health problems, or bleeding disorders before taking SD PILL TABLET as a precaution. SD PILL TABLET is not recommended for use in patients with liver or heart problems. Avoid taking SD PILL TABLET with heavy meals or with grapefruit juice.

The most common side effects of taking SD PILL TABLET are flushing, headache, dizziness, blurred vision, muscle pain, nausea, tiredness, increased sweating, restlessness, and a decrease in sex drive. Consult your doctor if any of these side effects trouble you.

Also, inform your doctor immediately if you experience any prolonged painful penile erections without sexual stimulation (priapism), experience dizziness upon standing up suddenly, or if you have sudden mood changes or suicidal thoughts after taking SD PILL TABLET.

Uses Of SD PILL TABLET

It is used by adult men to:

Help improve blood flow to the penis
Manage early ejaculation

How SD PILL TABLET Works

SD PILL TABLET contains two medicines called dapoxetine and sildenafil. Dapoxetine delays ejaculation by blocking the reuptake of a chemical messenger called serotonin between the nerve cells. This increases the activity of serotonin within the brain, which therefore increases the time taken to release the semen (ejaculate) during sexual intercourse.

Sildenafil works by improving the blood supply to the penis. It works by blocking the effects of certain enzymes (PDE5) in the body that limit blood flow to the penis. As a result, it relaxes the blood vessels supplying the penis and improves blood flow.

How to use SD PILL TABLET

Take SD PILL TABLET as advised by your physician. Swallow SD PILL TABLET with a glass of water. Do not chew or crush the medicine. Take SD PILL TABLET, preferably before meals, and at least 30 minutes to 1 hour before planning to have sexual intercourse. Your doctor will decide the correct dose and duration of therapy for you depending on your age, body weight, and health condition.

Side Effects Of SD PILL TABLET

Common

dizziness, headache
nausea, vomiting
feeling irritable, anxious, agitated, or restless
sensation of numbness, tingling or prickling
increased sweating
hot flushes
diarrhea, constipation, wind, and stomach pain
problems in sleeping or strange dreams, difficulty in concentration
tiredness or sleepiness
blocked nose
a rise in blood pressure
decrease in sex drive
ringing in the ears
blurred vision, color tinge to vision, visual disturbance
dry mouth

Uncommon

fainting
change in mood, feeling overly excited or feelings of paranoia (feeling threatened)
feeling confused, disoriented, or unable to think clearly
abnormal heartbeat (slow or fast heart rate)
feeling depressed or nervous
feeling hot, jittery, abnormal, or drunk
eye problems (eye irritation, pain or redness, watery eyes, double vision, abnormal sensation in the eye, seeing light flashes)
low blood pressure
feeling itchy or cold sweats
spinning sensation
abnormal taste
skin rash
muscle pain
reduced sense of touch
signs of inflammation of the lining of the nose, such as a runny nose or sneezing
upper abdominal pain
signs of gastroesophageal reflux disease, such as heartburn
presence of blood in urine or semen
pain in the arms or legs
nosebleed

Rare

penile bleeding
dry nose
throat tightness, numbness of the mouth
temporary decrease in blood flow to the brain
sudden decrease or loss of hearing
sudden onset of sleep (Ex. narcolepsy)
urge to empty the bowel

Stop taking SD PILL TABLET and contact your doctor if you experience any of the following side effects:

severe allergic reaction (such as wheeziness, difficulty breathing or dizziness, swelling of the face, lips, eyelids, or throat)
prolonged or painful erection (priapism)
chest pain, especially during or after sexual intercourse
severe skin reactions (blistering of skin around the mouth, genitals or eyes, severe peeling and swelling of skin along with fever)
sudden decline or loss of vision
fits or seizures
fainting or lightheadedness while standing
mood changes, suicidal thoughts, or a tendency for self-harming

How To Manage Side Effects

Diarrhea

Hydrate yourself by drinking plenty of fluids, such as water or fruit juices. Consuming ORS can also be beneficial. Do not self-manage diarrhea on your own. Consult your doctor if your diarrhea becomes uncontrollable.

Dizziness Or Drowsiness

Try to rest and relax. Get enough sleep. Avoid driving or operating any tools or machines completely while you are feeling dizzy. Do not consume excessive alcohol, as it could aggravate your dizziness. Consult your doctor if your dizziness worsens or if you feel dizzy upon standing up suddenly.

Headache

Rest and relax. Keep yourself hydrated by drinking plenty of fluids, such as water or electrolytes. Applying a pain-relieving balm to your forehead can be beneficial. Do not consume excessive alcohol, as it could aggravate your headache. Consult your doctor if your headache worsens.

Nausea And Vomiting

Take SD PILL TABLET with or just after meals. Stick to simple meals. Avoid eating oil-rich or spicy foods. Consult your doctor if your vomiting worsens.

Warning & Precautions

Pregnancy

Contraindicated

SD PILL TABLET is not intended for use by women.

Breastfeeding

Contraindicated

SD PILL TABLET is not intended for use by women.

Driving and Using Machines

Contraindicated

Do not drive or operate any machines if you experience dizziness or blurred vision after taking SD PILL TABLET.

Alcohol

Contraindicated

Avoid consumption of alcohol while taking SD PILL TABLET, as it may cause dizziness or sleepiness.

Kidney

Use with Caution

SD PILL TABLET should be used with caution in patients with kidney problems. Therefore, consult your doctor before taking it.

Liver

Contraindicated

SD PILL TABLET is not recommended for use in patients with moderate or severe liver diseases. Therefore, consult your doctor before taking it.

Allergy

Contraindicated

Do not take SD PILL TABLET if you are allergic to Dapoxetine or Sildenafil.

Lungs

Use with Caution

SD PILL TABLET should be used with caution in patients with pulmonary arterial hypertension. Therefore, consult your doctor before taking it.

Heart Disease

Contraindicated

SD PILL TABLET is not recommended for use in patients with heart problems (such as heart failure, low blood pressure, or problems with the heart rhythm). Therefore, consult your doctor before taking it.

Use In Pediatrics

Contraindicated

SD PILL TABLET is not recommended for use in children and adolescents (below 18 years). Therefore, consult your doctor before taking it.

Use In Geriatrics

Contraindicated

SD PILL TABLET is not recommended for use in elderly patients (aged 65 years or older). Therefore, consult your doctor before taking it.

Others

SD PILL TABLET is not recommended for use if you:

have a history of fainting
have or ever had signs of mania, such as feeling overexcited, irritable, or not being able to think clearly
have severe depression
have recently had a stroke
have low blood pressure
have signs of retinitis pigmentosa (rare inherited eye disease) such as decreased vision at night or in low light and loss of side vision

Before taking SD PILL TABLET, inform your doctor if you:

have a history of feeling dizzy due to low blood pressure
have schizophrenia (a psychiatric disease)
have epilepsy
have a history of bleeding or blood clotting problems
have or are at risk of developing glaucoma
have sickle cell anemia (an abnormality of red blood cells)
have leukemia (cancer of blood cells)
have multiple myeloma (cancer of the bone marrow)
have a deformity in your penis
have Peyronie’s disease (the development of fibrous scar tissue in the penis that causes painful erection)
currently have a stomach ulcer
have bleeding problems such as hemophilia
are alcoholic

Interactions

A. Drug-Drug Interactions:

Before taking SD PILL TABLET, inform your doctor if you are taking any of the following medicines, such as:

nitrates or amyl nitrites (used for reliving chest pain) Ex. nitroglycerin, isosorbide dinitrite
other medicines used to manage prostate problems or blood pressure, such as alpha blockers (Ex. silodosin, doxazosin)
riociguat (a medicine used to manage increased pressure in the lungs)
medicines used to manage depression (Ex. fluoxetine, sertraline, citalopram, escitalopram, amitriptyline, isocarboxazid, selegiline, nefazodone and St. john’s wort)
thioridazine (a medicine used to manage a mental disorder called schizophrenia)
lithium (a medicine used to manage bipolar disorder)
tryptophan (a medicine used to induce sleep)
medicines used to manage migraines (Ex. almotriptan, sumatriptan)
non-steroidal anti-inflammatory drugs (used to manage pain and inflammation) Ex. ibuprofen and aspirin
tramadol (a medicine used to relieve pain)
antibiotics (used to manage bacterial infections) Ex. telithromycin, linezolid, erythromycin, and clarithromycin
medicines used to manage HIV infection (Ex. ritonavir, saquinavir, nelfinavir, atazanavir, amprenavir and fosamprenavir)
medicines used to manage fungal infections (such as ketoconazole, itraconazole and fluconazole)
warfarin (a medicine used to manage blood clotting)
other medicines used to manage erectile dysfunction (such as tadalafil or vardenafil)
medicines used to manage high blood pressure or chest pain (such as verapamil and diltiazem)
aprepitant (a medicine that is used to manage nausea)
medicines used to reduce anxiety and alter mental stability (Ex. morphine, pethidine, alprazolam, midazolam, clonazepam, MDMA (ecstasy) or lysergic acid diethylamide)

B. Drug-Food Interactions:

Avoid drinking grapefruit juice within 24 hours prior to taking SD PILL TABLET, as it may increase the level of SD PILL TABLET in the body. Also, taking SD PILL TABLET with a heavy meal may delay its onset of action.

Overdosage:

If you or anyone else accidentally took more SD PILL TABLET, consult your doctor immediately or visit the nearby hospital. The symptoms of an overdose are nausea and vomiting.

Synopsis

Drug	:	Dapoxetine, Sildenafil
Pharmacological Category	:	Selective serotonin reuptake inhibitors (SSRI), Phosphodiesterase type 5 inhibitors
Therapeutic Indication	:	Problems in erection, to manage early ejaculation
Dosage Forms	:	Tablet

More Information

Keep SD PILL TABLET out of reach of children
Store SD PILL TABLET at room temperature

FAQs About SD PILL TABLET

Q: What is SD PILL TABLET used for?

A: SD PILL TABLET is used in adult men to help improve blood flow to the penis and to manage early ejaculation by balancing certain chemicals in the brain.

Q: How do I take SD PILL TABLET?

A: Take SD PILL TABLET at least 30 minutes to 1 hour before sexual intercourse. It should be taken, preferably before meals, for a faster onset of action. Avoid taking SD PILL TABLET with heavy meals. Swallow the medicine with a glass of water. Do not crush or chew the medicine.

Q: Can I take SD PILL TABLET daily?

A: SD PILL TABLET is generally prescribed as one dose per day. However, your doctor will decide whether you can take this medicine daily or not, depending upon your health condition. Do not take SD PILL TABLET more than once a day without consulting your doctor.

Q: How long does it take for SD PILL TABLET to start working?

A: It may take around 30 minutes to 1 hour for SD PILL TABLET to start working; therefore, take this medicine at least one hour before planning to have sex. This time may vary from person to person depending on their health condition. Avoid taking heavy meals while taking SD PILL TABLET, as it could further delay the onset of action.

Q: Who can take SD PILL TABLET?

A: SD PILL TABLET can be used for adult men with sexual problems. It is not suitable for use in healthy men who do not have any sexual problems or in men who are not sexually stimulated. It is also not advisable for use in children or adolescents (aged below 18 years).

Q: What happens if I consume a higher dose of SD PILL TABLET than prescribed by my doctor?

A: Do not consume a higher dose of SD PILL TABLET than the one prescribed by your doctor, as it may lead to unwanted side effects. Your doctor will decide the correct dose for you, depending on your age and disease condition. If the prescribed dose does not help you, contact your doctor.

Q: Can men be taking SD PILL TABLET father a child?

A: There is no confirmed proof that SD PILL TABLET could affect fertility in men. However, it is better to consult your doctor before taking SD PILL TABLET if you are planning to father a child.

Q: Is SD PILL TABLET safe?

A: Yes. SD PILL TABLET is safe to use. But inform your doctor immediately if you experience painful, prolonged erections or chest pain after taking SD PILL TABLET. It can also cause headache, dizziness, flushing or muscle pain in some individuals. Contact your doctor if they bother you.

Q: Can I consume alcohol while taking SD PILL TABLET?

A: Avoid consumption of alcohol while taking SD PILL TABLET, as it could reduce the effectiveness of SD PILL TABLET.

Q: How long do the effects of SD PILL TABLET last?

A: The effects of SD PILL TABLET would normally last for 4 hours. However, this time may vary from person to person depending on their age and health condition. Consult your doctor if the effects of SD PILL TABLET do not last long.

Q: Can SD PILL TABLET make you last longer?

A: Yes. SD PILL TABLET delays the release of sperm (ejaculation) in patients suffering from premature ejaculation.

Q: Will taking SD PILL TABLET affect my sexual life?

A: Long-term use of SD PILL TABLET may negatively impact your sexual life. It may cause sexual problems, such as a decrease in sex drive. Talk to your doctor if you are facing any sexual problems while taking SD PILL TABLET.

Q: How does SD PILL TABLET work?

A: SD PILL TABLET contains two medicines called dapoxetine and sildenafil. Dapoxetine delays ejaculation by blocking the reuptake of a chemical messenger called serotonin between the nerve cells. This increases the activity of serotonin within the brain, which therefore increases the time taken to release the semen (ejaculate) during sexual intercourse.

Q: Can I stop taking SD PILL TABLET on my own without consulting a doctor?

A: Do not stop taking SD PILL TABLET without consulting your physician, as sudden discontinuation of SD PILL TABLET may cause withdrawal symptoms like sleeping problems or dizziness.

Q: Can SD PILL TABLET cause bipolar disorder?

A: SD PILL TABLET may cause mood changes in some individuals. Inform your doctor immediately if you experience any sudden changes in mood. Also, it is important to inform you doctor if you already have bipolar disorder as a precaution before starting management with SD PILL TABLET.

References

1. KD. Tripathi. Drugs Used in Mental Illness: Antidepressant and Antianxiety Drugs & Androgens and Drugs for Erectile Dysfunction. Essentials of medical pharmacology. Seventh edition. 2013. Page – 303 & 464.

2. Murat Tukan, Mehmet Gokhan Culha and Ege Can Serefoglu. Efficacy and safety of dapoxetine/sildenafil combination tablets in the treatment of men with premature ejaculation and concomitant erectile dysfunction—DAP-SPEED Study. ResearchGate. March 2019. [Accessed on 3rd June 2022]. https://www.researchgate.net/publication/330766365_Efficacy_and_safety_of_dapoxetinesildenafil_combination_tablets_in_the_treatment_of_men_with_premature_ejaculation_and_concomitant_erectile_dysfunction-DAP-SPEED_Study

3. Menarini - Von Heyden GmbH. Electronic medicines compendium (EMC). [Revised in June 2021] [Accessed on 3rd June 2022]. https://www.medicines.org.uk/emc/files/pil.1269.pdf

4. Pharmadox Healthcare Ltd. Electronic medicines compendium (EMC). [Revised in December 2021] [Accessed on 3rd June 2022]. https://www.medicines.org.uk/emc/files/pil.13551.pdf

5. DA SUTRA 30X TABLET. Hetero Healthcare. Limited. [Accessed on 3rd June 2022]. https://www.heterohealthcare.com/da-sutra-30x-tablet

Author Details

Written By Dr. N. Sai Swaroop - Pharm.D

Reviewed For Accuracy By Dr. Pushpraj Singh - MBBS

Last updated on 12 Dec 2023 | 05:32 PM(IST)