Quick Links

Introduction About KODEX T SYRUP

KODEX T SYRUP is a combination of Codeine and Triprolidine which belongs to the group of medicines called Antitussives and Antihistamines respectively. KODEX T SYRUP is used for the symptomatic management of dry cough. A dry or unproductive cough does not produce mucus can occur due to conditions like cold, flu.

Before taking KODEX T SYRUP inform your doctor if you have or ever had a stomach ulcer, pre-existing ischaemic heart disease, history of arrhythmia, epilepsy, increased intraocular pressure/narrow angle glaucoma, prostatic hypertrophy, bladder neck obstruction, diabetes, gallbladder disease or gallstones, bronchial asthma or urethral stricture. KODEX T SYRUP should not be used in pregnant women, breastfeeding women, children and adolescents below 18 years of age.

KODEX T SYRUP is recommended with caution in elderly and debilitated patients. The common side effects of KODEX T SYRUP are dizziness, mood changes, tiredness, nausea, vomiting, increased heartbeat, loss of appetite, headache, blurred vision, dry mouth and constipation. Consult your doctor if any of the above side effects worsen or persists for a longer duration.

Uses Of KODEX T SYRUP

Used for the symptomatic management of dry cough

How KODEX T SYRUP Works

KODEX T SYRUP is a combination of Codeine and Triprolidine. Codeine is a cough suppressant which suppresses cough by reducing the activity of special cough centre in the brain. Triprolidine is an antiallergic and it works by blocking the action of a chemical messenger (histamine) which may trigger cough due to allergy.

How to use KODEX T SYRUP

Take KODEX T SYRUP as advised by your physician. Shake well before use. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.

Side Effects Of KODEX T SYRUP

Common

dizziness, drowsiness
mood changes
tiredness
weakness
nausea, vomiting
increased heartbeat
loss of appetite
headache
blurred vision
dry mouth
constipation
urinary retention
coordination problems

Rare

hypersensitivity reactions

Stop taking KODEX T SYRUP and contact your doctor immediately if you experience any of the following side effects:

serious allergic reactions that may cause swelling of face or throat, wheezing or sudden difficulties in breathing

How To Manage Side Effects

Constipation

Drink lots of fluids, such as water or fruit juice to keep yourself hydrated. Do not consume any medicine on your own without consulting your doctor.

Dizziness Or Drowsiness

Try to rest and relax. Get enough sleep. Avoid driving or operate any machines while you are feeling dizzy. Do not consume alcohol, as it can aggravate your dizziness. Contact your doctor if the symptom did not improve.

Headache

Rest and relax. Drink plenty of fluids such as water or electrolytes and apply a pain-relieving balm on the head if necessary. Do not consume alcohol. Contact your doctor if the symptom did not improve.

Nausea And Vomiting

Stick to simple meals. Avoid eating rich or spicy food. Consult your doctor if the symptom gets worse.

Stomach Pain

Try to rest and relax. Eat and drink slowly or try to have smaller and frequent meals. Keep a heat pad on your stomach. If the symptom does not improve, contact your doctor.

Warning & Precautions

Pregnancy

Contraindicated

KODEX T SYRUP is not recommended during pregnancy. Consult your doctor for advice.

Breastfeeding

Contraindicated

KODEX T SYRUP is not recommended in breastfeeding women. Consult your doctor for advice.

Driving and Using Machines

Use with Caution

KODEX T SYRUP may cause dizziness, blurred vision or the inability to think clearly which could affect your ability to drive.

Alcohol

Contraindicated

Consumption of alcohol is not recommended while taking KODEX T SYRUP.

Kidney

Contraindicated

KODEX T SYRUP is not recommended for patients with moderate to severe renal impairment. Consult your doctor before taking.

Liver

Contraindicated

KODEX T SYRUP is not recommended for patients with severe hepatic impairment. Consult your doctor before taking.

Allergy

Contraindicated

Do not take KODEX T SYRUP if you are allergic to Codeine, Triprolidine or any other ingredients of this medicine.

Lungs

Contraindicated

KODEX T SYRUP is not recommended for patients with lower respiratory tract symptoms, including asthma, bronchitis, bronchiectasis or at risk of developing respiratory failure. Consult your doctor before taking.

Heart Disease

Contraindicated

KODEX T SYRUP is not recommended for patients with a history of arrhythmia. Consult your doctor for advice.

Use In Pediatrics

Contraindicated

KODEX T SYRUP is not recommended in children and adolescents below 18 years of age. Consult your doctor for advice.

Use In Geriatrics

Use with Caution

KODEX T SYRUP should be used with caution in elderly patients. Consult your doctor for advice.

Others

KODEX T SYRUP is not recommended for use if you:

have head injury or raised intracranial pressure
have ulcerative colitis

Before taking KODEX T SYRUP, inform your doctor if you:

have epilepsy
have narrow angle glaucoma
have prostatic hypertrophy
have bladder neck obstruction
have diabetes
have gallbladder disease or gallstones
have urethral stricture

Interactions

A. Drug-Drug interactions:

Before taking KODEX T SYRUP inform your doctor if you are taking any of the following medicine:

anti-allergic medicines (Ex. diphenhydramine, cetirizine, brompheniramine, diphenhydramine, fexofenadine)
medicine to suppress cough (Ex. dextromethorphan)
antidepressants (Ex. duloxetine, sertraline, paroxetine, fluvoxamine, trazodone)
narcotic analgesics (Ex. hydrocodone, bupropion, morphine, oxycodone)
medicine to manage anxiety (Ex. alprazolam, diazepam, lorazepam, oxazepam, temazepam)
medicines used for seizures (Ex. phenytoin, carbamazepine)

Overdosage:

If you or anyone else accidentally takes too much of KODEX T SYRUP, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose are extreme sleepiness, confusion, or shallow breathing.

Synopsis

Drug	:	Codeine, Triprolidine
Pharmacological Category	:	Antitussives, Antihistamines
Therapeutic Indication	:	Manages dry cough
Dosage Forms	:	Syrup, Cough Syrup, Linctus

More Information

Keep KODEX T SYRUP out of reach of children
Store at room temperature

FAQs About KODEX T SYRUP

Q: Will KODEX T SYRUP be more effective if taken in more than recommended doses?

A: No, taking a higher dose than recommended may not be more effective, rather it may increase the chances of having certain serious side effects and toxicity. If you experience increased severity of your symptoms, that are not relieved by the recommended doses, consult your doctor for re-evaluation.

Q: Can KODEX T SYRUP used for pregnant women?

A: KODEX T SYRUP is generally not recommended for use in pregnant women. Consult your doctor before taking it.

Q: What if I forget to take KODEX T SYRUP?

A: If you miss a dose of KODEX T SYRUP take it as soon as possible. However, if it is time for your next scheduled dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Q: How does KODEX T SYRUP help in reliving dry cough?

A: KODEX T SYRUP is a combination of Codeine and Triprolidine. Codeine is a cough suppressant which suppresses cough by reducing the activity of special cough centre in the brain. Triprolidine is an antiallergic and it works by blocking the action of a chemical messenger (histamine) which may trigger cough due to allergy.

References

1.KD. Tripathi. Drugs for Cough and Bronchial Asthma. Chapter 16 Essentials of medical pharmacology. Seventh edition. 2017.

2. Triprolidine. National Library of medicine. January 2017. [Accessed on 3rd March 2023] https://www.ncbi.nlm.nih.gov/books/NBK548164/#:~:text=Triprolidine%20belongs%20to%20the%20ethanolamine,common%20cold%20and%20allergic%20rhinitis.

3. Pfizer Limited. Codeine and Triprolidine Syrup. [Revised in January 2020] [Accessed on 3rd March 2023] https://labeling.pfizer.com/ShowLabeling.aspx?id=14885

4. Abbott Pharmaceuticals. Codeine and Triprolidine Syrup. [Accessed on 3rd March 2023] https://www.abbott.in/products/therapy-areas.respiratory.html#tabsComp

5. J.K. Aronson ScienceDirect. Codeine. [Accessed on 3rd March 2023] https://www.sciencedirect.com/topics/neuroscience/codeine

6. Medsafe. Triprolidine. [Revised in September 2020] [Accessed on 3rd March 2023] https://www.medsafe.govt.nz/Consumers/cmi/CoughandCold/Triprolidine1.pdf

Author Details

Written By Dr. Janet.C - Pharm.D

Reviewed For Accuracy By Dr. Rajnikant - MBBS, MD (Physiology)

Last updated on 03 Mar 2023 | 05:45 PM(IST)