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Introduction About FLEXIBERT 180 TABLET

FLEXIBERT 180 TABLET contains Fexofenadine which belongs to the group of medicines called Antihistamines. It is used in adults and children (aged above 12 years) to provide relief from symptoms of hay fever or seasonal allergic rhinitis. It is also used to provide relief from symptoms associated with chronic idiopathic urticaria in adults and children (aged above 12 years), generally characterized by symptoms such as itching, swelling and rashes.

Seasonal allergic rhinitis is an inflammatory condition of the upper airways that occurs in response to exposure to airborne allergens (such as tree, grass and weed pollens) in sensitized individuals which is generally characterized by symptoms such as nasal stuffiness, itchy nose/throat/eyes, headache and weakness. Avoid drinking fruit juices such as grapefruit, orange and apple while taking FLEXIBERT 180 TABLET as it may reduce the effect of this medicine. FLEXIBERT 180 TABLET is not recommended for use in patients allergic to Fexofenadine.

Before taking FLEXIBERT 180 TABLET, inform your doctor if you or your child has intolerance to certain sugars (such as lactose), liver, kidney and/or heart problem. FLEXIBERT 180 TABLET is not recommended for use in pregnant women unless advised by the doctor and it is not indicated for use in breastfeeding women. The medicine is recommended for use in children and adolescents (aged above 12 years). Consult your child’s doctor before administering this medicine to your child. It is used with caution in elderly patients above 65 years of age. The most common side effects of taking FLEXIBERT 180 TABLET are headache, drowsiness, dizziness and nausea. Consult your doctor if any of the side effects worsen.

Uses Of FLEXIBERT 180 TABLET

Used in adults and children (aged above 12 years) to provide:

Relief from the symptoms of hay fever (seasonal allergic rhinitis)
Relief from the symptoms of chronic idiopathic urticaria

How FLEXIBERT 180 TABLET Works

FLEXIBERT 180 TABLET works by blocking the actions of H1 histamine receptors (chemical substance responsible for allergic reaction) that results in managing the occurrence of seasonal allergic rhinitis and idiopathic urticaria thus providing relief from the symptoms associated with both conditions.

How to use FLEXIBERT 180 TABLET

Take FLEXIBERT 180 TABLET as advised by your physician. Swallow this medicine and do not crush or chew the medicine. Correct dose and duration will be decided by your doctor depending upon your age, body weight and disease condition.

Side Effects Of FLEXIBERT 180 TABLET

Common

Headache
Drowsiness
Dizziness
Nausea

Uncommon

Tiredness
Sleepiness

Stop taking FLEXIBERT 180 TABLET and contact your doctor immediately if you experience any of the following side effects:

Signs of serious allergic reaction such as swelling of the face, lips, tongue or throat and difficulty breathing

How To Manage Side Effects

Dizziness Or Drowsiness

Try to rest and get enough sleep. Try to avoid driving or operating any tools or machines while you feel dizzy. Limit consumption of alcohol, as it can aggravate dizziness. Consult and inform your doctor if the symptom worsens.

Headache

Apply hot or cold-water bag on your child’s head. Try to take rest in a quiet and dark room. Drink tea or coffee. Massage on scalp or head with mild pressure. In case of no improvement in the symptom, consult your doctor.

Nausea And Vomiting

Try to take FLEXIBERT 180 TABLET with or just after a meal or a snack. Stick to simple meals. Avoid eating oil rich, fried or spicy food. Consult your doctor if the symptom gets worse.

Tiredness

Make sure you take rest and drink plenty of fluids. Avoid or limit the consumption of alcohol. Try to take FLEXIBERT 180 TABLET at a time when you can sit down (or lie down) when the symptoms are at their worst. Avoid driving or using tools or machinery until you feel well.

Warning & Precautions

Pregnancy

Monitoring required

FLEXIBERT 180 TABLET is generally not recommended for use in pregnant women unless considered clearly necessary. Consult your doctor before taking it.

Breastfeeding

Contraindicated

FLEXIBERT 180 TABLET is not recommended for use in breastfeeding women. Consult your doctor for advice.

Driving and Using Machines

Use with Caution

Do not drive or operate machines if FLEXIBERT 180 TABLET makes you dizzy or sleepy. Consult your doctor before taking FLEXIBERT 180 TABLET.

Kidney

Use with Caution

FLEXIBERT 180 TABLET should be used with caution in patients with kidney problems. Consult your doctor before taking it.

Liver

Use with Caution

FLEXIBERT 180 TABLET should be used with caution in patients with liver problems. Consult your doctor before taking it.

Allergy

Contraindicated

Do not take FLEXIBERT 180 TABLET if you are allergic to Fexofenadine or any other ingredients of this medicine.

Heart Disease

Use with Caution

FLEXIBERT 180 TABLET should be used with caution in patients with heart disease. Consult your doctor before taking it.

Use In Pediatrics

Safe

FLEXIBERT 180 TABLET is recommended for use in children and adolescents (aged 12 to 18 years). Consult your child’s doctor for advice before administering this medicine to your child.

Use In Geriatrics

Use with Caution

FLEXIBERT 180 TABLET is used with caution in elderly patients above 65 years of age. Before taking FLEXIBERT 180 TABLET, consult your doctor.

Others

Before taking FLEXIBERT 180 TABLET, inform your doctor if you:

Are intolerant to certain sugars such as lactose

Interactions

A. Drug-Drug interactions:

Before taking FLEXIBERT 180 TABLET, inform your doctor if you are taking any of the following medicines:

Aluminum and magnesium (medicines used to relieve symptoms of heart burn or indigestion)

B. Drug-Food interaction:

Avoid drinking fruit juices such as grapefruit, orange and apple while taking FLEXIBERT 180 TABLET as it may reduce the effect of the medicine. Consult your doctor before taking it.

Overdosage:

If you or anyone else accidentally take too much of FLEXIBERT 180 TABLET, consult your doctor immediately or visit the nearby hospital. Signs of overdose are dizziness, drowsiness, weakness and dry mouth.

Synopsis

Drug	:	Fexofenadine
Pharmacological Category	:	Antihistamines
Therapeutic Indication	:	Seasonal allergic rhinitis, Chronic idiopathic urticaria
Dosage Forms	:	Tablet, Oral suspension, Syrup

More Information

Storage

Keep FLEXIBERT 180 TABLET out of reach of children
Store at room temperature

FAQs About FLEXIBERT 180 TABLET

Q: What is FLEXIBERT 180 TABLET and why is it given?

A: FLEXIBERT 180 TABLET contains Fexofenadine which is an Antihistamine, used in adults and children (aged above 12 years) to provide relief from symptoms of hay fever or seasonal allergic rhinitis. It is also used to provide relief from symptoms associated with chronic idiopathic urticaria in adults and children (aged above 12 years), generally characterized by symptoms such as itching, swelling and rashes.

Q: Is FLEXIBERT 180 TABLET safe to be used in pregnant and breast-feeding women?

A: FLEXIBERT 180 TABLET is not recommended for use in pregnant women unless clearly necessary which is also not recommended for use in breast feeding women. Consult your doctor before taking this medicine.

Q: What side effects are seen with FLEXIBERT 180 TABLET?

A: Like all medicines, FLEXIBERT 180 TABLET can cause side effects, although not everybody gets them. The most common side effects of taking FLEXIBERT 180 TABLET are headache, drowsiness, dizziness and nausea. Contact and inform your doctor if the symptoms worsen.

Q: How FLEXIBERT 180 TABLET should be taken?

A: Take FLEXIBERT 180 TABLET as advised by your physician. Swallow this medicine and do not crush or chew the medicine. Correct dose and duration will be decided by your doctor depending upon your age, body weight and disease condition.

Q: Does FLEXIBERT 180 TABLET causes dizziness?

A: Yes, FLEXIBERT 180 TABLET causes dizziness as it is the commonest side effect associated with the use of this medicine. If such side effects are experienced, then lie or sit down immediately when you feel dizzy. If you're feeling a severe episode of vertigo, lie in a dark and quite place with eyes closed. Talk to your doctor if the symptom does not improve.

References

1. KD. Tripathi. Histamine and Antihistaminics. Essentials of medical pharmacology. Seventh edition. 2013. Page-166.

2. Kari L. Craun; Mark P. Schury. Fexofenadine. NIH National Library of Medicine. National center for biotechnology information. May 2022. [Accessed on 9th June 2022] https://www.ncbi.nlm.nih.gov/books/NBK556104/

3. Meji Pharma Spain S.A. Health Product Regulatory Authority (HPRA). [Revised in February 2021]. [Accessed on 9th June 2022] https://www.hpra.ie/img/uploaded/swedocuments/d5c3161e-75cd-47f8-b87d-0ffc7514e638.pdf

4. Sanofi-aventis U.S. LLC. U.S. Food & Drug Administration (FDA). [Revised in 2007] [Accessed 9th June 2022] https://www.accessdata.fda.gov/drugsatfda_docs/label/2008/020872s018,021963s002lbl.pdf

5. Dr. Reddy’s Laboratories (UK) Ltd. Electronic Medicines Compendium (EMC). [Revised in August 2018]. [Accessed 9th June 2022] https://www.medicines.org.uk/emc/files/pil.3488.pdf

Useful Diagnostic Tests

Allergen-specific immunoglobulin E (IgE) antibody test

Author Details

Written By Dr. Janet.C - Pharm.D

Reviewed For Accuracy By Dr. M N Himaja - MBBS

Last updated on 11 Jul 2024 | 03:54 PM(IST)