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Introduction About RESPICURE M 10/5MG TABLET

RESPICURE M 10/5MG TABLET is used in the management of signs and symptoms of allergic rhinitis (sneezing, runny or stuffy nose, nasal itching, red, watery or itchy eyes, throat irritation, cough, headache and tiredness), chronic idiopathic urticaria (allergic skin reaction with red raised itchy bumps on skin) and bronchial asthma.

It contains a combination of two medicines namely, Levocetirizine and Montelukast which effectively reduces the allergic reactions triggered in your body. Take RESPICURE M 10/5MG TABLET under medical supervision. Usually, it is prescribed for 14-15 days or for more duration based on your health condition. Follow the dosing schedule appropriately to effectively control the triggers to allergic responses.

Avoid consumption of alcohol while taking this medicine as it could make you feel drowsier. Before taking this medicine, inform your doctor if you have kidney problems, history of asthma, pregnant or breastfeeding as a precaution. It is ideal for use in adults and adolescents (aged 15 years or older).

The most common side effects of taking RESPICURE M 10/5MG TABLET are upper respiratory tract infection, fever, cough, inflammation of the pharynx, dryness of mouth, headache and sleepiness. Talk to your doctor if any of these side effects trouble you.

Uses Of RESPICURE M 10/5MG TABLET

It is used in the management of signs and symptoms associated with:

How RESPICURE M 10/5MG TABLET Works

RESPICURE M 10/5MG TABLET contains two medicines namely, levocetirizine and montelukast.

Levocetirizine: It is an antihistamine that blocks the action of histamine, a chemical released by the immune system during an allergic reaction. By blocking histamine, it reduces symptoms like itching, sneezing, runny nose, and watery eyes.
Montelukast: It is a leukotriene receptor antagonist that blocks the action of leukotrienes, chemicals in the body that cause inflammation, swelling, and constriction of the airways. This helps in reducing airway inflammation and controlling asthma symptoms, as well as treating allergic rhinitis.

Together, this combination provides relief from allergy symptoms while also controlling asthma attacks and reducing inflammation in the airways.

How to use RESPICURE M 10/5MG TABLET

Take RESPICURE M 10/5MG TABLET as advised by your physician
Typically, the medicine is taken once daily, preferably in the evening, or as directed by your doctor.
This medicine can be taken with or without food but taking it with food may help reduce any potential stomach upset.
Swallow the medicine with a glass of water. Do not crush or chew the medicine
Stick to the dosage and duration prescribed by your doctor. Do not increase the dose or stop the medication without consulting your healthcare provider.

Side Effects Of RESPICURE M 10/5MG TABLET

Common Side Effects of RESPICURE M 10/5MG TABLET:

upper respiratory infection
cough, cold, fever or flu-like symptoms
pharyngitis (inflammation of the pharynx)
headache and tiredness
dizziness, sleepiness
nausea, vomiting, dry mouth, thirst, stomach pain, diarrhea, indigestion
otitis media (inflammation or infection of the ears)
skin rash
bleeding from the nose
muscle pain, joint pain

Stop taking this medicine and contact doctor immediately if you experience any of the following side effects:

neuropsychiatric disorders (such as agitation, anxiety, depression, disorientation, hyperactivity, nightmares, hallucinations, insomnia, memory impairment, walking in the sleep, tremor, attention disturbance)
thoughts of harming or killing yourself (suicidal ideation)

Warning & Precautions

Pregnancy

Consult your doctor

Before taking RESPICURE M 10/5MG TABLET, inform your doctor if you are pregnant or think you may be pregnant as a precaution.

Breastfeeding

Use with Caution

It is not known whether the combination of levocetirizine and Montelukast can pass through breast milk. Therefore, this medicine should be used with caution in breastfeeding women.

Driving and Using Machines

Use with Caution

Do not drive or operate any machines if you experience sleepiness/drowsiness, fatigue or physical weakness.

Alcohol

Consult your doctor

Avoid consumption of alcohol while taking RESPICURE M 10/5MG TABLET as it could cause reduction in alertness and impairment of performance.

Kidney

Consult your doctor

RESPICURE M 10/5MG TABLET is not recommended for use in patients with severe kidney impairment. It should be taken with extreme caution in patients with kidney disease.

Liver

Use with Caution

RESPICURE M 10/5MG TABLET should be taken with caution in patients with liver disease.

Allergy

Contraindicated

Do not take RESPICURE M 10/5MG TABLET if you are allergic to Montelukast or Levocetirizine.

Lungs

Contraindicated

RESPICURE M 10/5MG TABLET is not recommended for use in patients with asthma attacks.

Use In Pediatrics

Consult your doctor

RESPICURE M 10/5MG TABLET can be used in adolescents (aged 15 years or older). For children aged below 15 years, you must consult your doctor for an optimum dosage.

Use In Geriatrics

Monitoring required

RESPICURE M 10/5MG TABLET should be used with caution in elderly patients (aged 65 years or above). Proper dose titrations and careful monitoring of kidney functions are required in such patients.

Others

RESPICURE M 10/5MG TABLET is not recommended for use if you:

have galactose intolerance (inherited condition in which the body cannot convert galactose to glucose)
have Lapp lactase deficiency (deficiency of the enzyme lactase in the body)
have glucose-galactose malabsorption
have phenylketonuria (release of phenylalanine in urine)

Before taking RESPICURE M 10/5MG TABLET, inform your physician if you:

have or at risk of having epilepsy
have scheduled allergy skin tests
have sensitivity to aspirin or other NSAIDs
have any predisposing factors of urinary retention (Ex. spinal cord lesion, prostatic hyperplasia)

Interactions

A. Drug-Drug interactions:

Before taking RESPICURE M 10/5MG TABLET, inform your doctor, if you are taking any of the following medicines:

gemfibrozil (used to control high blood cholesterol levels)
CNS depressants (Ex. phenobarbital), phenytoin (used to manage epilepsy)
rifampicin (used to manage tuberculosis)
ritonavir (a medicine used to manage viral infections)
theophylline (a medicine used to manage asthma)

Overdosage:

If you or anyone else take too much of RESPICURE M 10/5MG TABLET, contact your doctor immediately or go to a hospital straight away. Overdosage symptoms of RESPICURE M 10/5MG TABLET might include stomach pain, thirst, sleepiness, headache, vomiting, hyperactivity, agitation, excitation and restlessness.

Synopsis

Drug	:	Levocetirizine, Montelukast
Pharmacological Category	:	H1 receptor antagonist, Leukotriene receptor antagonist
Therapeutic Indication	:	Allergic rhinitis, Bronchial asthma, Chronic idiopathic urticaria
Dosage Forms	:	Tablet, Capsule, Softgel capsule, Dispersible tablet, Syrup, Suspension

More Information

To know more about this medicine:

FAQs About RESPICURE M 10/5MG TABLET

Q: How long does it take for RESPICURE M 10/5MG TABLET to provide relief from symptoms?

A: Following oral administration with RESPICURE M 10/5MG TABLET, it is believed to provide relief from the symptoms of allergy within 30 minutes to an hour.

Q: Can RESPICURE M 10/5MG TABLET be used to manage acute asthma attacks?

A: No, it is only used to reduce the risk of having an asthma attack. It should not be used on an asthma attack that has been started already.

Q: Can RESPICURE M 10/5MG TABLET be used in infants?

A: There is no proper research done on the safety and effectiveness of levocetirizine + montelukast combination in infants aged between 6-12 years of age. Therefore, consult your child’s doctor for the optimum dosage and duration of therapy.

Q: Can RESPICURE M 10/5MG TABLET make you feel sleepy?

A: Yes, RESPICURE M 10/5MG TABLET may make you feel sleepy or drowsy. Try to rest and relax.

Q: Is RESPICURE M 10/5MG TABLET safe to use in patients with kidney problems?

A: RESPICURE M 10/5MG TABLET is not recommended for use in patients with severe kidney impairment. It should be taken with extreme caution in patients with kidney disease.

References

KD. Tripathi. Histamines and Antihistamines & Drugs for cough and bronchial asthma. Essentials of medical pharmacology. Seventh edition. 2013. Page – 166-168 & 228-229.
TusharKanti Sarkar. Effectiveness and safety of levocetirizine 10 mg versus a combination of levocetirizine 5 mg and montelukast 10 mg in chronic urticaria resistant to levocetirizine 5 mg: A double-blind, randomized, controlled trial. ResearchGate. Indian Journal of Dermatology, Venereology and Leprology. June 2017. [Accessed on 13th October 2021] click here
Torrent pharmaceuticals Ltd. Lezyncet-M. Torrentian.com. April 2020. [Accessed on 13th October 2021] click here
RND Laboratories. Laboratories division. Rnd Kast-L10 Tablets. [Accessed on 13th October 2021] click here
Glenmark Pharmaceuticals s.r.o. Tillomed Laboratories Ltd. And Glenmark Pharmaceuticals Europe Limited. Electronic Medicines Compendium (EMC). [Revised in November 2019] [Accessed on 13th October 2021] click here
Accord Healthcare Limited. Electronic Medicines Compendium (EMC). [Revised in September 2020] [Accessed on 13th October 2021] click here

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Author Details

Written By Srilekha. R - B.Pharm

Reviewed For Accuracy By Dr. Rajnikant - MBBS, MD (Physiology)

Last updated on 21 Nov 2024 | 12:53 PM(IST)