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Introduction About CANDIDAC C GEL

CANDIDAC C GEL is a combination of Clindamycin and Clotrimazole which belongs to the group of medicines called Antibiotics and Antifungal agents respectively. It is used to manage vaginal (genital) infections (Ex. vaginal candidiasis, bacterial vaginosis and mixed vaginal infections). It can also reduce vaginal itching and irritation caused due to infections. and

CANDIDAC C GEL is meant for intravaginal use only. Carefully apply the medicine deep into the vagina as far as possible. Wash your hands before and after application. Closely follow the dose-related instructions given by your doctor to achieve better results. Skipping doses in between the therapy or stopping the therapy without consulting your doctor may not result in adequate infection control.

While using CANDIDAC C GEL, do not engage in vaginal intercourse or use any vaginal products (such as tampons or douches). This medicine may weaken condoms and diaphragms. Therefore, choose an alternative method for contraception.

Before using CANDIDAC C GEL inform your doctor if you have diabetes, weak immune system or any stomach problems (such as colitis). You must also inform your doctor if you are pregnant or breastfeeding or currently having periods before using CANDIDAC C GEL as a precaution.

CANDIDAC C GEL is generally safe and well tolerated with fewer side effects like mild vaginal itching or irritation, vaginal discharge and mild diarrhea. Consult your doctor if they trouble you.

Uses Of CANDIDAC C GEL

Manage vaginal (genital) infections
Reduces vaginal itching and irritation caused due to infections

How CANDIDAC C GEL Works

CANDIDAC C GEL is effective in managing both bacterial and fungal genital infections. It works by killing the susceptible microorganism that causes infection within the body. It contains two medicines namely clindamycin and clotrimazole.

Clindamycin is an antibacterial agent. It blocks the production of certain bacterial proteins which is essential for the bacteria to survival. This action manages the further growth and multiplication of bacteria within the body

Clotrimazole is an antifungal agent. It blocks the production of certain chemicals (ergosterol) within the fungal cell which is essential for its survival. This action kills the susceptible fungi and manages the further spread of infection.

How to use CANDIDAC C GEL

Apply CANDIDAC C GEL as directed by your physician. It should be used only in and around the vagina or the genital area. CANDIDAC C GEL comes in a tube along with an applicator. Remove the cap from the tube and connect the nozzle end of the applicator with the tube.

Gently squeeze the sufficient medicine from the tube into the applicator. The marking present in the applicator may help you to measure the correct dosage as instructed by your doctor.

Remove the applicator from the tube and lie down on your back with legs wide apart. Gently insert the applicator into the vagina. Press the plunger present in the applicator downwards to release the medicine in the vagina.

Remove the applicator from the vagina after application. To cleanse the applicator, pull the plunger outside and wash it with mild soap and warm water.

If you want to apply CANDIDAC C GEL to the external parts of vagina, take the required quantity of CANDIDAC C GEL and apply it at the required sites of the genital area (such as vulva, labia minora, clitoris and vaginal orifice).

Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and health condition.

Side Effects Of CANDIDAC C GEL

Common

mild vaginal itching, irritation or burning sensation
vaginal discharge
mild diarrhea
difficulty in passing stools
back pain
pain and burning sensation while passing urine
increased urge to pass urine, cloudy urine
foamy urine
heavy menstrual bleeding

Rare

Stop using CANDIDAC C GEL and contact your doctor immediately if you experience any of the following side effects:

signs of allergic reactions (such as skin rash, itching, swelling of face, mouth, tongue and throat causing difficulty in breathing)
worsening of vaginal conditions (including severe vaginal pain, itching and discharge)
severe stomach pain and/or bloody stools
severe skin rash with raised lumps, hives and blistering

How To Manage Side Effects

Mild Diarrhea:

Hydrate yourself by drinking plenty of fluids, such as water or fruit juices. Consuming ORS can also be beneficial. Do not self-manage diarrhea on your own. Consult your doctor if your diarrhea becomes uncontrollable or if you see blood in your stools.

Warning & Precautions

Pregnancy

CANDIDAC C GEL should be used in pregnant women only if it is considered necessary by the physician. Therefore, consult your doctor for advice before using it.

Breastfeeding

CANDIDAC C GEL should be used with caution among breastfeeding women. Therefore, consult your doctor before using it.

Driving and Using Machines

CANDIDAC C GEL is unlikely to affect your ability for driving or handling any heavy tools or machines.

Allergy

Do not use CANDIDAC C GEL if you are allergic to clindamycin or to clotrimazole.

Others

CANDIDAC C GEL is not recommended for use if you:

have a history of stomach conditions (such as regional enteritis, ulcerative colitis)

Before using CANDIDAC C GEL, inform your doctor if you:

have a habit of using tampons or douches
are currently on your monthly periods
have diabetes
have a weak immune system
have HIV infection

Use in Paediatrics:

CANDIDAC C GEL is not recommended for use in children and adolescents (aged below 18 years). Therefore, consult your doctor before using it.

Use in Geriatrics:

Consult your doctor before using this medicine in case of elderly patients (aged 65 years or above).

Interactions

A. Drug-Drug interactions:

Before using CANDIDAC C GEL, inform your doctor if you are taking any of the following medicines such as:

Other antibiotics (such as erythromycin)
Other antifungal agents (such as Amphotericin-B and nystatin)

Overdosage:

If you or anyone else accidentally swallowed the medicine, consult your doctor immediately or visit the nearby hospital.

Synopsis

Drug	:	Clindamycin, Clotrimazole
Pharmacological Category	:	Lincosamide Antibiotics, Azole Antifungals
Therapeutic Indication	:	Genital infections
Dosage Forms	:	Vaginal Suppositories, Pessarie, Vaginal Capsule, Vaginal Tablet, Gel, Cream

More Information

Keep CANDIDAC C GEL out of reach from children
Store CANDIDAC C GEL at room temperature

FAQs About CANDIDAC C GEL

Q: What is the use of CANDIDAC C GEL?

A: CANDIDAC C GEL is used to manage vaginal (genital) infections (Ex. vaginal candidiasis, bacterial vaginosis and mixed vaginal infections). It can also be used to reduce vaginal itching and irritation.

Q: How CANDIDAC C GEL works?

A: CANDIDAC C GEL works by killing the susceptible microorganism that causes infection within the body. It is effective in managing both bacterial and fungal genital infections.

Q: How to use CANDIDAC C GEL?

CANDIDAC C GEL is for intravaginal use only. Lie down on your back and place your legs wide apart. Carefully apply the medicine deep into the vagina using the applicator. Wash your hands before and after inserting the medicine.

Q: How long should I use CANDIDAC C GEL?

A: Generally, management with CANDIDAC C GEL may last for 3-7 consecutive days. Therefore, you need to use CANDIDAC C GEL for the stipulated duration prescribed by your doctor. Failing to do so may not result in adequate infection control.

Q: What shall I do if I forgot to use CANDIDAC C GEL?

A: If you forgot to use CANDIDAC C GEL, use it as soon as you remember. However, if it is time for the next application, skip the missed one and take the next dose. Do not insert too many medicines to compensate the missed doses.

Q: Is CANDIDAC C GEL safe?

A: CANDIDAC C GEL is safe at doses prescribed by the physician. Therefore, do not alter the dose of CANDIDAC C GEL without consulting your doctor.

Q: Can I stop using CANDIDAC C GEL without consulting your doctor?

A: No. You should not stop using CANDIDAC C GEL without consulting your doctor as it may reduce its effectiveness. Therefore, use CANDIDAC C GEL for the stipulated duration recommended by your doctor to achieve maximum results.

Q: Can CANDIDAC C GEL be used in pregnant women?

A: CANDIDAC C GEL should be used in pregnant women only if it is considered necessary by the physician. Therefore, inform your doctor before using it.

Q: What are the side effects of using CANDIDAC C GEL?

A: In some patients, CANDIDAC C GEL may cause mild vaginal itching or irritation, vaginal discharge and mild diarrhea. Consult your doctor if they trouble you.

References

1. KD. Tripathi. Macrolide and other Antibacterial antibiotics. Antifungal drugs. Essentials of Medical Pharmacology. 7th edition. 2013. Page – 756, 763, & 792.

2. Geannyne Villegas-Rivera, K.L. Castellanos, J.C. Magaña, Rafael Zarate. Efficacy and safety of clindamycin / clotrimazole vaginal cream in Mexican patients with cervicovaginitis. ResearchGate. April 2011. [Accessed on 13th January 2023]. https://www.researchgate.net/publication/287521682_Efficacy_and_safety_of_clindamycin_clotrimazole_vaginal_cream_in_Mexican_patients_with_cervicovaginitis

3. Pfizer Service Company BVBA. Dalacin® Cream 2% clindamycin phosphate. Electronic Medicines Compendium. [Revised in August 2022]. [Accessed on 13th January 2023]. https://www.medicines.org.uk/emc/files/pil.1080.pdf

4. Boots Pharmaceuticals. Thrush 1% w/w Cream (Clotrimazole). Electronic Medicines Compendium. [Accessed on 13th January 2023]. https://www.medicines.org.uk/emc/files/pil.8388.pdf

5. Actavis Pharma, Inc. Clotrimazole Cream. Dailymed.com. [Revised in September 2022]. [Accessed on 13th January 2023]. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=e8468943-1087-4317-8b64-236f15d7f465

6. Pfizer Ltd. Cleocin® clindamycin phosphate vaginal cream, USP. U.S. Food and Drug Administration. [Revised in March 2020]. [Accessed on 13th January 2023]. https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/050680s018,050767s017lbl.pdf

7. Syscan CL. Torrent Pharmaceutical Ltd. [Revised in June 2014]. [Accessed on 13th January 2023]. https://www.torrentian.com/pisheet/Upload/PI_Sheet/1550.pdf

8. Ikon Remedies Pvt Ltd. Candidac C Gel. [Accessed on 13th January 2023]. https://www.ikonremedies.com/product/candidac-c-gel/

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Author Details

Written By Srilekha. R - B.Pharm

Reviewed For Accuracy By Dr. Karthikeyan Rajagopal - M. Pharma, Ph.D (Pharmacology)

Last updated on 13 Jan 2023 | 05:15 PM(IST)