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Introduction About CABGOLIN 0.5 TABLET

Cabgolin 0.5mg Tablet contains Cabergoline, a dopamine receptor agonist. It helps in lowering prolactin levels in the body and is commonly used for managing hyperprolactinemia, pituitary gland disorders, and menstrual irregularities. It is also prescribed for stopping breast milk production in certain medical situations.

Take Cabgolin 0.5 Tablet with food to reduce the risk of side effects and aim to take it at the same time each day for the best results. Always follow your doctor’s instructions regarding the dosage and duration of treatment. The prescribed dose will depend on your specific condition and response to treatment. Swallow the tablet whole with a glass of water and continue taking it as directed by your healthcare provider.

Before taking Cabgolin 0.5 Tablet, inform your doctor if you have a history of high blood pressure after childbirth or any heart-related issues, if you are pregnant, planning to conceive, or currently breastfeeding or taking any other medications, as they might interact with this medicine and affect its effectiveness.

Your doctor may recommend regular monitoring of your blood pressure throughout the course of treatment to ensure your safety.

Common side effects of taking Cabgolin 0.5 Tablet are nausea, headache, dizziness and low blood pressure (hypotension). If these side effects persist or become severe, inform your doctor immediately. To manage dizziness, avoid driving or operating machinery and stand up slowly from a seated or lying position.

Uses Of CABGOLIN 0.5 TABLET

Hyperprolactinemia (high prolactin levels in blood)
Suppresses Lactation (breast milk production) in certain medical situations.
Menstrual irregularities, lack of periods or light menstruation, infertility
Prolactinoma or pituitary gland disorders

Cabgolin 0.5 Tablet for Hyperprolactinemia:

Cabgolin Tablet effectively reduces elevated prolactin levels in individuals with hyperprolactinemia.
It helps restore normal hormone balance, reducing symptoms such as unexplained breast milk production (galactorrhea) in non-nursing individuals.

Cabgolin Tablets for menstrual irregularities:

This medicine helps regulate menstrual cycles disrupted due to elevated prolactin levels.
It also restores normal ovulation, making it an effective for infertility caused by hormonal imbalance.
Alleviates symptoms like heavy or missed periods, improving overall reproductive health.
Supports hormonal balance for women experiencing irregular or painful periods linked to prolactin abnormalities.

Cabgolin Tablets for Pituitary gland disorders:

Cabgolin lowers elevated prolactin levels, restoring normal pituitary gland function and reducing symptoms like irregular periods and infertility.
It effectively reduces the size of prolactin-secreting pituitary tumors, alleviating symptoms like headaches and vision disturbances.
Non-Invasive Treatment: Cabgolin provides a medical alternative to surgery for managing prolactin-related pituitary disorders.

How CABGOLIN 0.5 TABLET Works

Cabgolin 0.5 works by lowering the levels of a hormone called prolactin in the body. Prolactin is produced by a small gland in your brain called the pituitary gland. When prolactin levels are too high, it can cause problems like irregular periods, difficulty getting pregnant, or unwanted breast milk production.

Cabgolin works by sending signals to your brain to reduce the amount of prolactin being made. By doing so, it helps restore normal hormone levels, improving your menstrual cycle, fertility, and stopping unwanted breast milk production.

This makes Cabgolin an effective treatment option for conditions caused by high prolactin levels, helping you feel better and support your reproductive health.

How to use CABGOLIN 0.5 TABLET

Cabgolin 0.5 Tablet should be taken exactly as prescribed by your doctor.
Swallow the medicine with a glass of water. Do not crush or chew the medicine.

Cabgolin 0.5mg dosage instructions:

Typically, Cabgolin is taken once or twice a week, depending on your doctor's instructions.

- The usual starting dose is 0.25 mg, which may be gradually increased based on your response to treatment. Your doctor will adjust the dose to suit your needs.
- Take the tablet by mouth with or without food.

Can I adjust my Cabgolin dosage myself?

No, you should never adjust your Cabgolin dosage on your own. Changing the dose without medical advice can lead to side effects such as dizziness, nausea, or a sudden drop in blood pressure. Always consult your doctor before making any changes to your medication regimen.

What happens if I miss a dose of Cabgolin 0.5?

If you miss a dose of Cabgolin, take it as soon as you remember, unless it’s close to your next scheduled dose. In that case, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for the missed one, as this can increase the risk of side effects.

What is the best time to take Cabgolin Tablets?

It's usually recommended to take Cabgolin in the evening or before bed to reduce the chance of side effects like dizziness or nausea.

Important Tips for Safe Use:

Avoid alcohol while taking Cabgolin as it may increase dizziness or low blood pressure.
Inform your doctor about any ongoing medications, supplements, or existing health conditions.
Do not stop the medication abruptly unless advised by your doctor.
Regular follow-up appointments are important to monitor prolactin levels and adjust the dosage as needed.

Side Effects Of CABGOLIN 0.5 TABLET

Like all medicines, Cabgoline 0.5mg tablet may cause certain side effects, although not everybody gets them.

Cabgolin tablet common side effects:

Nausea or vomiting
Dizziness or light-headedness

Fatigue or weakness
Headache
Stomach pain or discomfort
Constipation

Possible Cabgolin side effects in men:

high sex drive or an increase in sexual thoughts or feelings Hpra

Possible Cabgolin side effects in women:

Breast pain or tenderness
Painful menstrual periods

Refer, medlineplus

When to Seek Medical Attention

If you experience severe side effects like

Chest pain, difficulty breathing, or persistent dizziness
Swelling of ankles or body parts
Strong impulse to gamble excessively despite serious personal or family consequences
Abnormal, uncontrollable increased sexual drive
Uncontrollable excessive shopping or spending or Binge eating

Long-Term Safety of Cabgolin Tablets:

Heart Valve Safety: Long-term Cabgolin use has been associated with a rare risk of heart valve fibrosis (thickening of heart valves). This risk is dose-dependent and more common at higher doses used for conditions like Parkinson’s disease. To know more, Long-term Safety of Cabergoline in hyperprolactinemia, NHS. Health Research Authority

Recommendation: Periodic heart monitoring (e.g., echocardiograms) is recommended, especially for patients on long-term therapy. Refer, Pfizer.Cabergoline

Mood Changes: Rarely, long-term use may cause mood changes, compulsive behaviors, or hallucinations, especially at higher doses.

How To Manage Side Effects

Dizziness Or Drowsiness

Prevent Sudden Movements:

Get up slowly: When moving from lying down to sitting or standing, take your time to avoid a sudden drop in blood pressure (orthostatic hypotension).
Stay Hydrated: Dehydration can exacerbate dizziness. Drink plenty of water throughout the day to maintain proper hydration levels.
Avoid alcohol: Alcohol can enhance dizziness
Limit caffeine: Excess caffeine may affect your blood pressure and worsen symptoms.
Eat Regularly: Low blood sugar can cause or worsen dizziness. Eat balanced meals and snacks throughout the day to keep your blood sugar levels stable.
Elevate Your Feet: If you feel dizzy, lie down and raise your feet above your heart to help blood flow to your brain.

Headache

Stay Hydrated: Dehydration can worsen headaches. Drink plenty of water throughout the day.
Rest in a Quiet, Dark Room: Bright lights and noise can make headaches worse. Resting in a calm environment can help alleviate symptoms.
Apply a Cold or Warm Compress: Place a cold pack on your forehead or a warm compress on the back of your neck, depending on which feels more soothing.
Practice Relaxation Techniques: Stress can exacerbate headaches. Try deep breathing and meditation.

Nausea And Vomiting

To reduce stomach irritation, take Cabergoline after a meal or snack.
Opt for bland, low-fat foods such as toast, crackers, or bananas to avoid triggering nausea
Sip small amounts of water, clear broth, or herbal teas throughout the day to stay hydrated.
Avoid large gulps of liquids, as they can worsen nausea.

Cabgolin 0.5 is generally not recommended for use in children under 16 years of age due to lack of proper safety data. Therefore, talk to your doctor for advice.

Use In Geriatrics

Use with Caution

Cabgolin 0.5 is generally not recommended for use in children under 16 years of age due to lack of proper safety data. Therefore, talk to your doctor for advice.

Others

Who Should Not Take Cabgolin 0.5mg?

Cabgolin 0.5 is not recommended for use if you have:

history of mental illness associated with childbirth (puerperal psychosis)
fibrotic reactions (scar tissue) affecting the abdomen, heart or lungs
swelling of hands and feet and a high blood pressure during pregnancy (preeclampsia, eclampsia)

Before taking Cabgolin 0.5 Tablet, inform your doctor if you have:

cold hands and feet (Raynaud’s syndrome)
peptic ulcer or GI haemorrhage (bleeding from the stomach and intestines)
history of serious mental disease (psychotic disorders)
just given birth you may be more at risk of certain conditions like high blood pressure, convulsion, stroke or mental health problems
increased blood pressure after giving birth

Safety Advice

1. Take the Medication as Prescribed: Always follow the dosage and schedule recommended by your doctor. Do not adjust the dose or frequency without consulting a healthcare provider, even if symptoms improve.

2. Monitor for Side Effects: Common Symptoms: Nausea, dizziness, headache, or fatigue. Serious Symptoms: Shortness of breath, chest pain, or severe abdominal discomfort. If any severe or unusual symptoms occur, seek medical attention immediately.

3. Avoid Driving or Operating Machinery: Cabgolin may cause dizziness or drowsiness. Avoid activities requiring alertness until you understand how the medication affects you.

4. Use Caution with Other Medications: Inform your doctor about all prescription and over-the-counter drugs, supplements, or herbal products you are taking. Be particularly cautious with antihypertensives, antipsychotics, or antibiotics, as these may interact with cabergoline.

5. Avoid Alcohol Consumption: Alcohol may exacerbate side effects like dizziness and nausea. Limiting or avoiding alcohol during treatment is strongly advised.

6. Do Not Stop Abruptly: Abruptly discontinuing Cabgolin may lead to rebound symptoms or worsening of the condition. If you need to stop the medication, consult your doctor for a tapering schedule.

Why Choose Netmeds to Buy Cabgolin?

Netmeds is a trusted and convenient online pharmacy where you can buy Cabgolin with confidence. Offering genuine and FDA-approved medications, Netmeds ensures you receive quality products at affordable prices. With easy online ordering, secure home delivery, and expert customer support, Netmeds makes it simple to get your medications delivered right to your doorstep. Choose Netmeds for a safe, reliable, and hassle-free purchase.

Drug - Drug interaction

Before taking Cabgolin Tablet, inform your doctor if you are taking any of the following medicine:

1.Antipsychotic Medications:

Interaction: Antipsychotics like haloperidol, chlorpromazine, and risperidone can reduce the effectiveness of cabergoline by blocking dopamine receptors.
Effect: May counteract the therapeutic benefits of CABGOLIN and exacerbate prolactin levels.
Advice: Avoid concomitant use; consult your doctor for alternatives.

2.Macrolide Antibiotics

Drugs Involved: Erythromycin, clarithromycin.
Interaction: These antibiotics can increase cabergoline blood levels by inhibiting its metabolism
Effect: Heightened risk of side effects such as nausea, dizziness, and low blood pressure.
Advice: Inform your doctor if you are on antibiotics to adjust the dose accordingly.

3.Blood Pressure Medications

Drugs Involved: Beta-blockers (atenolol, propranolol), diuretics, and antihypertensives
Interaction: CABGOLIN can amplify the blood-pressure-lowering effects of these medications
Effect: May cause severe hypotension (low blood pressure), especially after standing.
Advice: Regularly monitor blood pressure and consult your physician if you experience symptoms like dizziness or fainting

4.Serotonin Receptor Agonists and Antagonists

Drugs Involved: Triptans (sumatriptan, zolmitriptan) or certain antidepressants (SSRIs, SNRIs)
Interaction: These drugs may interfere with cabergoline’s action at dopamine receptors
Effect: Reduced effectiveness of Cabgolin or an increased risk of serotonin syndrome
Advice: Use with caution and under medical guidance.

5.Ergot Derivatives

Drugs Involved: Ergotamine, dihydroergotamine.
Interaction: Combining cabergoline with other ergot derivatives increases the risk of additive side effects
Effect: Potential for severe vasospasm or hypertension
Advice: Avoid simultaneous use unless explicitly prescribed by a doctor

Synopsis

Drug	:	Cabergoline
Pharmacological Category	:	Dopamine agonists
Therapeutic Indication	:	Reduces breast milk production and manages hormonal disturbances
Dosage Forms	:	Tablet

More Information

Cabgolin for Fertility Issues:

Cabgolin (cabergoline 0.5 mg) can be used in some cases to help manage infertility caused by hyperprolactinemia (a condition where there is an abnormally high level of prolactin in the blood). Elevated prolactin levels can interfere with ovulation in women and reduce testosterone levels in men, leading to infertility.

It is effective only if infertility is linked to hyperprolactinemia. It will not help with infertility caused by other factors like tubal blockage or low ovarian reserve.

How Cabgolin Helps with Infertility:

Restores Ovulation in Women: By lowering prolactin levels, Cabgolin helps restore normal ovulation and menstrual cycles, which are essential for conception.
Improves Hormonal Balance: Reduces prolactin to normal levels, helping maintain the hormonal environment necessary for fertility.
Supports Male Fertility: In men, it can increase testosterone production and improve sperm quality if infertility is due to high prolactin.

Cabgolin side effects vs benefits:

Benefits	Side Effects
Reduces High Prolactin Levels: Cabgolin helps to lower elevated prolactin levels, which can restore normal hormonal function and improve fertility.	Nausea: Some people may experience nausea, especially at the start of treatment.
Improves Ovulation in Women: By lowering prolactin, Cabgolin can help restore regular ovulation cycles, improving chances of conception.	Headache: A common side effect, especially when the dosage is increased.
Helps in Menstrual Irregularities: It can restore normal menstrual cycles disrupted by hyperprolactinemia.	Dizziness: Some users may experience dizziness, especially upon standing up quickly.
Supports Male Fertility: It helps to normalize testosterone levels in men, improving sperm quality and fertility.	Low Blood Pressure: Cabgolin may cause a drop in blood pressure, leading to dizziness or fainting.
Suppresses Lactation in Certain Conditions: Cabgolin is used to stop milk production in cases like stillbirth, abortion, or miscarriage.	Fatigue or Drowsiness: Some individuals may feel tired or sleepy while on the medication.
Improves Hormonal Balance: Cabgolin helps in regulating prolactin and restoring hormonal balance, aiding in fertility treatment.	Abdominal Pain or Bloating: Digestive issues such as discomfort or bloating may occur.
Minimal Side Effects with Proper Dosage: With gradual dosage increases, side effects can be minimized or avoided.	Mental Health Effects: In rare cases, Cabgolin may cause mood changes, depression, or impulsive behaviors.

Other best medicines to reduce Prolactin hormones:

Alternate Brands	Active Ingredient	Best Price and Discounts
Caberlin 0.25mg Tablet 4'S	Cabergoline 0.25mg	Rs. 247 (52% cheaper)
CABERSMART 0.25 Tablet 4's	Cabergoline 0.25mg	Rs. 217.80 (58% cheaper)
Cabliz 0.5mg Tablet 2'S	Cabergoline 0.5mg	Rs. 235.84 (55% cheaper)
CB Lin 0.5mg Tablet 2'S	Cabergoline 0.5mg	Rs. 205.92 (60% cheaper)

FAQs About CABGOLIN 0.5 TABLET

Q: Does Cabgolin cause nausea or vomiting?

A: Yes, Cabgolin can cause nausea as a common side effect, especially during the initial stages of treatment. If nausea persists, consult your healthcare provider for potential solutions or dosage adjustments.

Q: How to safely increase Cabgolin dosage?

A: Cabgolin dosage should only be increased under the supervision of a healthcare provider. Typically, the dosage is gradually increased to minimize side effects. Follow your doctor's instructions carefully and never adjust the dosage without medical advice.

Q: Can Cabgolin cause weight loss or gain?

A: Cabgolin may lead to mild weight changes in some individuals. While weight loss is not a typical side effect, some patients may experience weight gain due to hormonal changes. Always monitor any significant weight changes and consult your doctor if concerned.

Q: Is headache a side effect of Cabgolin?

A: Yes, headaches are a common side effect of Cabgolin. These headaches are usually mild and temporary, but if they become severe or persistent, contact your healthcare provider.

Q: Cabgolin side effects on pregnancy or fertility?

A: Cabgolin is used to regulate prolactin levels and can improve fertility in both men and women. However, it is not recommended during pregnancy unless prescribed by your doctor. Always inform your healthcare provider if you are pregnant or planning to become pregnant.

Q: What are the most common side effects of Cabgolin?

A: The most common side effects of Cabgolin include nausea, headache, dizziness, fatigue, and low blood pressure. These side effects are generally mild and may decrease with time.

Q: How do I reduce Cabgolin side effects?

A: To reduce Cabgolin side effects, start with a low dose as prescribed and gradually increase it. Taking the medication with food can also help reduce nausea. If dizziness occurs, rise slowly from a sitting or lying position.

Q: How often should I take Cabgolin 0.5mg tablets?

A: Cabgolin 0.5mg is typically taken twice a week, but the frequency may vary depending on your doctor's recommendation. Follow your doctor's dosing instructions carefully for optimal results.

Q: Is it safe to take Cabgolin 0.5mg daily?

A: While Cabgolin 0.5mg is often taken twice a week, your doctor may adjust the dosage depending on your condition. Taking it daily is not recommended unless specifically prescribed by your healthcare provider.

Q: Can Cabgolin 0.5mg be taken with food?

A: Yes, Cabgolin 0.5mg should ideally be taken with food to help reduce the chances of nausea and gastrointestinal discomfort. Swallow the tablet whole with a glass of water.

Q: What is the correct Cabgolin dosage for long-term use?

A: The long-term dosage of Cabgolin varies based on individual needs. Your doctor will determine the right dose after evaluating your condition, typically starting with a low dose and adjusting it based on response and tolerance.

Q: How much does Cabgolin 0.5 tablet cost?

A: The cost of Cabgolin 0.5mg tablet on Netmeds is approximately ?525 for a pack of 4 tablets. Prices may vary depending on promotions or offers available at the time of purchase.

Q: How long does Cabergoline take to show results?

A: Most people experience improvements within a few weeks of regular use. However, the exact duration may vary depending on individual conditions.

References

1. Laurence L. Brunton, John S. Lazo, Keith L. Parker. Hormones and Hormones antagonist. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 11th edition. 2006. Page – 1500.

2. Tulloch KJ, Dodin P, Tremblay-Racine F, Elwood C, Money D, Boucoiran I. Cabergoline: a review of its use in the inhibition of lactation for women living with HIV. J Int AIDS Soc. 2019 June. [Accessed on December 23rd, 2024] click here

3. Pfizer Italia S.r.l. Electronic Medicines Compendium (EMC). [Revised in October 2020] [Accessed on December 23rd, 2024] click here

4. Pfizer Italia S.r.L. Health Products Regulatory Authority (HPRA). [Revised in March 2017] [Accessed on December 23rd, 2024] click here

5. Cabergoline tablet. DailyMed: National Library of Medicine: National Institute of Health. [Revised in July 2020] [Accessed on December 23rd, 2024]

6. Teva UK Ltd. Cabergoline. [Revised in October 2021] [Accessed on December 23rd, 2024] click here

Useful Diagnostic Tests

Prolactin - (PRL)

Author Details

Written By Srilekha. R - B.Pharm

Reviewed For Accuracy By Dr. Venkatesh Poludasu - MBBS

Last updated on 02 Jan 2025 | 05:04 PM(IST)