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Introduction About XALIDERM SOLUTION

XALIDERM SOLUTION is a combination of Coal tar, and Salicylic acid which belongs to a group of medicines known as Keratolytics and Keratoplastics respectively. It is used to manage conditions such as dandruff, psoriasis of scalp, psoriasis, neuro dermatitis, hyper keratotic skin conditions, keratoderma, seborrhaeic dermatitis and acne.

XALIDERM SOLUTION is not recommended for use in infected, damaged or open skin, or blisters filled with pus (pustules). XALIDERM SOLUTION should be used with caution in patients having broken or inflamed skin. XALIDERM SOLUTION is not recommended for use during first trimester of pregnancy and should be used with caution in breast-feeding woman.

XALIDERM SOLUTION is not recommended for use in children and adolescents below 12 years of age. The most common side effects of this medicine are scalp irritation, skin conditions like acne and staining of cloth, skin, and hair. Consult your doctor if the side effects worsen or persists for a longer duration.

Uses Of XALIDERM SOLUTION

It is used to manage:

dandruff
psoriasis of scalp
psoriasis
neuro dermatitis
hyper keratotic skin conditions
keratoderma
seborrhaeic dermatitis
acne

How XALIDERM SOLUTION Works

XALIDERM SOLUTION effectively reduces scalp conditions where Coal tar works by decreasing the keratinocyte (type of skin cell which is increased in disease conditions) proliferation through inhibition of DNA which is necessary for the cell growth and multiplication. Salicylic acid works by softening the scaly patches and causes shedding of the outer layer of the affected scalp region.

How to use XALIDERM SOLUTION

Use XALIDERM SOLUTION exactly as your doctor has told you. It is for external use only. Shake the bottle thoroughly before use. Wash your hands before and after use. Massage XALIDERM SOLUTION in the wet scalp and rinse it. Apply and massage for 5minutes, rinse thoroughly with water. Avoid contact with eyes.

Side Effects Of XALIDERM SOLUTION

Common

scalp irritation
skin conditions like acne
staining of cloth, skin, and hair

Stop using XALIDERM SOLUTION and contact your doctor immediately if you experience any of the following side effects:

allergic reactions like rash, swelling of the face or mouth, or breathing difficulties
eye irritation
unusual hair loss or hair thinning
eczema or itchiness with skin rash
sunlight sensitivity
skin irritation with dryness, redness, itchiness, and burning sensation
rash, pain or swelling at the application site

How To Manage Side Effects

Skin rash Or Itching

Try to avoid hot showers because it may cause skin irritation. Avoid frequent contact and rubbing over the affected area. Use sunscreen and protective clothing when outdoors. If this symptom does not get better, consult your doctor.

Warning & Precautions

Pregnancy

Contraindicated

XALIDERM SOLUTION is not recommended for use during first trimester of pregnancy. Consult your doctor for advice before using.

Breastfeeding

Use with Caution

XALIDERM SOLUTION should be used with caution in breastfeeding women. Consult your doctor before using.

Allergy

Contraindicated

Do not use XALIDERM SOLUTION if you are allergic to Coal tar, Salicylic acid, or any other ingredients of this medicine.

Use In Pediatrics

Contraindicated

XALIDERM SOLUTION is not recommended for use in children and adolescents below 12 years of age. Your doctor will decide the correct dose or select a suitable alternative therapy for your child. Consult your doctor before using.

Others

XALIDERM SOLUTION is not recommended for use if you:

have infected, damaged or open skin, or blisters filled with pus (pustules)

Before using XALIDERM SOLUTION, inform your doctor if you:

have broken or inflamed skin

Interactions

A. Drug-Drug interactions:

Before using XALIDERM SOLUTION, inform your doctor if you are taking any of the following medicine:

chlorothiazide, chlorthalidone (medicines used to excrete excess body fluid)
tetracyclines, doxycycline, minocycline (used to manage bacterial infections)
phenothiazines (used to reduce anxiety, fear, tension)

Overdosage:

If you or anyone else accidentally used too much of XALIDERM SOLUTION, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose are skin irritation, and increased sensitivity to sunlight.

Synopsis

Drug	:	Coal tar, Salicylic acid
Pharmacological Category	:	Keratolytic agents, Keratoplastics
Therapeutic Indication	:	Manages scalp conditions
Dosage Forms	:	Lotion, Scalp solution, Solution, Ointment, Soap

More Information

Keep XALIDERM SOLUTION out of reach of children
Store XALIDERM SOLUTION at a temperature below 25°C

FAQs About XALIDERM SOLUTION

Q: What is XALIDERM SOLUTION and why is it given?

A: XALIDERM SOLUTION is a combination of Coal tar, and Salicylic acid which belongs to a group of medicines known as Keratolytics and Keratoplastics respectively. It is used to manage conditions such as dandruff, psoriasis of scalp, psoriasis, neuro dermatitis, hyper keratotic skin conditions, keratoderma, seborrhaeic dermatitis and acne.

Q: How to use XALIDERM SOLUTION?

A: Always use XALIDERM SOLUTION exactly as your doctor has told you. It is for external use only. Shake the bottle thoroughly before use. Wash your hands before and after use. Massage XALIDERM SOLUTION in the wet scalp and rinse it. Avoid contact with eyes.

Q: What precautions need to be taken while using XALIDERM SOLUTION?

A: Caution should be exercised not to use XALIDERM SOLUTION in broken or inflamed skin since it may cause skin irritation. Avoid contact with eyes and if XALIDERM SOLUTION gets into eyes, rinse it with clean water. Avoid sunlight or sun beds exposure or if it is unavoidable wear protective clothing and sunscreen.

Q: Is XALIDERM SOLUTION safe for use in children?

A: XALIDERM SOLUTION is not recommended for use in children and adolescents below 12 years of age. Your doctor will decide the correct dose or select a suitable alternative therapy for your child.

References

1. KD Tripathi. Drugs Acting on Skin and Mucous Membranes. Essentials of medical pharmacology. Eighth Edition. 2019. Page- 951, 955.

2. R. Torsekar and Manjyot M. Gautam. Topical Therapies in Psoriasis. NIH National Library of Medicine, National centre for biotechnology information. PubMed Central. August 2017. [Accessed 10th October 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5518573/

3. Joshua A. Zeichner. Use of Topical Coal Tar Foam for the Treatment of Psoriasis in Difficult-to-treat Areas. NIH National Library of Medicine, National centre for biotechnology information. PubMed Central. September 2010. [Accessed 10th October 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2945847/#:~:text=The%20mechanism%20of%20action%20of,subsequent%20inhibition%20of%20keratinocyte%20proliferation.&text=Coal%20tar%20is%20thought%20to,keratinocytes%20of%20patients%20with%20psoriasis.

4. Stiefel Laboratories (Ireland) Ltd. Electronic Medicines Compendium (EMC). [Revised in October 2019] [Accessed 11th October 2022] https://www.medicines.org.uk/emc/files/pil.2161.pdf

5. Beccair, LLC. Dailymed. [Revised in March 2022] [Accessed 10th October 2022] https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=0a77e90e-a33a-43f3-80a0-a16a6902a735&type=display

6. Innovative Pharmaceuticals Pvt Ltd. Salicare Lotion. [Accessed 10th October 2022] https://www.innovativepharma.in/product/salicare-lotion/

7. MIMS. Coal tar-Topical. [Accessed 10th October 2022] https://www.mims.com/malaysia/drug/info/coal%20tar/patientmedicine/coal%20tar%20-%20topical

Author Details

Written By Dr. Janet.C - Pharm.D

Reviewed For Accuracy By Dr. Janet. C - Pharm.D

Last updated on 31 Mar 2023 | 04:46 PM(IST)