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Introduction About VASOCON INJECTION

VASOCON INJECTION contains Adrenaline which belongs to the group of medicines called Sympathomimetics. It is used during emergency situations to manage severe allergic reactions (anaphylaxis), cardiac arrest (loss of heart functions) and anaphylactic shock (sudden drop in blood flow due to an allergic reaction).

Anaphylaxis can be defined as a severe, potential life-threatening medical condition characterized by severe decrease in blood pressure, heart function, skin rash, nausea, swelling of the face, lips, tongue, or throat causing difficulty in breathing or swallowing. It is caused when an individual accidentally gets exposed towards certain chemicals (such as insect stings or bites, foods, drugs, sera, diagnostic testing substances and other allergens) that can trigger an allergic reaction in him.

VASOCON INJECTION can also be used to increase blood pressure in patients suffering from low blood pressure caused due to septic shock. It also helps in inducing mydriasis (dilation of the pupils) prior to an eye surgery after diluting the medicine properly using an ophthalmic irrigating solution.

Before receiving VASOCON INJECTION inform your doctor if you have any liver, kidney, or severe heart problems. You must also inform your doctor if you have diabetes, hypertension, glaucoma, thyroid disorders, atherosclerosis, or any other brain disorders.

Inform your doctor before receiving VASOCON INJECTION if you are pregnant or breastfeeding. The common side effects of receiving VASOCON INJECTION are tremors, pounding heartbeat, headache, sweating or dizziness. Inform your doctor if any of these side effects worsens.

Uses Of VASOCON INJECTION

It is used to:

manage severe allergic reactions (anaphylaxis)
manage anaphylactic shock
manage cardiac arrest and to restore blood pressure
induce mydriasis (dilation of the pupil) prior to an eye surgery

How VASOCON INJECTION Works

VASOCON INJECTION is a powerful cardiac stimulant. It works by binding to the alpha and beta receptors of the adrenergic system. This action, stimulates the heart, improves heart functions, and helps the heart to pump more blood smoothly. It also increases blood pressure among patients suffering from low blood pressure. It is also a powerful bronchodilator which relaxes the smooth muscle of the airway tract. This helps in reducing breathing difficulties caused due to anaphylactic reactions.

How to use VASOCON INJECTION

VASOCON INJECTION will be given only by a doctor or by a trained healthcare professional into the vein (intravenously) or into the muscle (intramuscularly) or under the skin (subcutaneously on the anterior part of the thigh).

It may also be administered into the eye (intracamerally) by an ophthalmologist prior to an eye surgery after diluting the medicine properly using an ophthalmic irrigating solution to cause pupil dilation.

Your doctor will decide the correct dose, duration of therapy and site of administration for you depending upon your age, body weight and health condition. However, care should be taken to not to administer VASOCON INJECTION in areas which generally have low blood supply (such as fingers, toes, ears, nose, genitals, or buttocks).

Side Effects Of VASOCON INJECTION

Common

anxiety or restlessness
apprehensiveness (a sense of misfortune)
shivering or shaking
weakness, dizziness
headache
sweating or irregular or pounding heart rate
pale appearance of the skin
nausea and vomiting
difficulty in breathing

Rare

Consult your doctor if you experience any of the following side effects after receiving VASOCON INJECTION:

severe allergic reactions (such as wheeziness, difficulty in breathing, swelling of the eyelids, face or lips, rash or itching all over the body)
signs of stress cardiomyopathy (such as chest pain, breathing difficulty, nausea, irregular heartbeat)

How To Manage Side Effects

Dizziness Or Drowsiness

Try to rest and relax. Avoid driving or operating heavy tools or machines while you are feeling dizzy. Avoid consumption of alcohol. Consult your doctor if your dizziness did not improve.

Headache

Try to take rest. Apply a pain-relieving balm on your forehead. If the symptom does not improve, consult with your doctor.

Warning & Precautions

Pregnancy

Monitoring required

VASOCON INJECTION should be used in pregnant women only if considered necessary by the physician. Therefore, inform your doctor before receiving VASOCON INJECTION if you are pregnant or think you may be pregnant or planning to have a baby.

Breastfeeding

Monitoring required

VASOCON INJECTION should be used in breastfeeding women only if considered necessary by the physician. Therefore, inform your doctor before receiving VASOCON INJECTION if you are breastfeeding.

Driving and Using Machines

Use with Caution

Do not drive or operate any machines if you experience dizziness or any other symptoms that affects your ability to drive after receiving VASOCON INJECTION.

Kidney

Use with Caution

VASOCON INJECTION should be used with caution in patients with kidney diseases. Therefore, consult your doctor before receiving it.

Liver

Use with Caution

VASOCON INJECTION should be used with caution in patients with liver disease. Therefore, consult your doctor before receiving it.

Allergy

Contraindicated

Do not receive VASOCON INJECTION if you are allergic to Adrenaline.

Heart Disease

Consult your doctor

VASOCON INJECTION is not recommended for use in patients with severe heart disease which involves an increased heart rate. It should be used with caution in patients with other heart problems (such as high blood pressure). Therefore, consult your doctor before receiving it.

Use In Pediatrics

Use with Caution

VASOCON INJECTION should be used with caution in children and adolescents (aged below 18 years). Therefore, consult your doctor before receiving it.

Use In Geriatrics

Use with Caution

VASOCON INJECTION should be used with caution in elderly patients. Therefore, consult your doctor before receiving it.

Others

VASOCON INJECTION is not recommended for use if you:

have any infection, disease, or tumor in the brain

Before receiving VASOCON INJECTION, inform your physician if you:

have chest pain
have blood vessel damage in your brain
have diabetes
have high blood pressure
have glaucoma (increased pressure in the eye)
have an overactive thyroid
have low potassium levels in the blood
have high calcium level in the blood
have phaeochromocytoma (a tumor present on the adrenal gland)
have a tumor in the prostate gland
have severe blood loss
are going to have a surgery under general anesthesia
have atherosclerosis (deposition of fat particles within the blood vessel that affects blood flow)

Interactions

A. Drug-Drug interactions:

Before receiving VASOCON INJECTION, inform your doctor if you are taking any of the following medicines such as:

antidepressants (used to manage depression) such as monoamine oxidase inhibitors (Ex. phenelzine, selegiline, isocarboxazid) or tricyclic antidepressants (Ex. imipramine, amitriptyline)
cardiac glycosides (used to manage abnormal heart rhythm) such as digoxin
guanethidine (a medicine used to high blood pressure)
diuretics (used to reduce edema by increasing urine output) such as hydrochlorothiazide, furosemide
inhaled general anesthetics (used to cause loss of consciousness) such as halothane
medicines used to control blood pressure (such as atenolol, propranolol, phentolamine, bisoprolol)
medicines used to manage diabetes (such as insulin or glipizide)
aminophylline and theophylline (medicines used to improve breathing)
corticosteroids (medicines used to manage inflammatory conditions in your body such as asthma or arthritis) Ex. dexamethasone, prednisolone, methylprednisolone
antihistamines (used to manage allergic conditions) Ex. diphenhydramine
medicines used to manage psychiatric disorders (such as chlorpromazine or fluphenazine)
medicines used to manage thyroid deficiency (Ex. thyroxine)
oxytocin (a medicine used to induce labor)
cough preparations (such as ambroxol, terbutaline, chlorpheniramine)

Overdosage:

VASOCON INJECTION will be given to you only by a doctor or nurse in a hospital, and so it is unlikely to receive an overdose. However, inform your doctor immediately if you experience any unusual symptoms.

Synopsis

Drug	:	Adrenaline
Pharmacological Category	:	Adrenergic Agonists
Therapeutic Indication	:	Anaphylactic reactions, Shock, Cardiac Arrest, Mydriasis
Dosage Forms	:	Injection

More Information

Keep VASOCON INJECTION out of reach of children
Store VASOCON INJECTION at room temperature
Protect VASOCON INJECTION from direct sunlight

FAQs About VASOCON INJECTION

Q: What is the use of VASOCON INJECTION?

A: VASOCON INJECTION is used during emergency situations to manage severe allergic reactions (anaphylaxis), cardiac arrest (loss of heart functions) and anaphylactic shock (sudden drop in blood flow due to an allergic reaction). It can also be used to increase blood pressure in patients suffering from low blood pressure caused due to septic shock. It also helps in inducing mydriasis (dilation of the pupils) prior to an eye surgery after diluting the medicine properly using an ophthalmic irrigating solution.

Q: Is VASOCON INJECTION safe?

A: VASOCON INJECTION is safe when used under proper medical supervision and at the prescribed doses.

Q: What VASOCON INJECTION does to my heart?

A: VASOCON INJECTION is a powerful cardiac stimulant. It works by binding to the alpha and beta receptors of the adrenergic system. This action, stimulates the heart, improves heart functions, and helps the heart to pump more blood smoothly. It also increases blood pressure among patients suffering from low blood pressure.

Q: Can VASOCON INJECTION be used to manage emergency conditions?

A: Yes. [GBNKEYWORD can be used during emergency conditions like cardiac arrest, anaphylaxis, and anaphylactic shock.

Q: What precautions do I need to follow while taking VASOCON INJECTION?

A: Patients receiving VASOCON INJECTION must inform their doctor about their pre-existing disease conditions such as high blood pressure, diabetes, glaucoma, liver problems, kidney problems, heart problems or thyroid problems. It is also important to inform your doctor if you are pregnant or breastfeeding before receiving VASOCON INJECTION.

Q: How VASOCON INJECTION is administered?

A: VASOCON INJECTION will be given only by a doctor or by a trained healthcare professional into the vein (intravenously) or into the muscle (intramuscularly) or under the skin (subcutaneously on the anterior part of the thigh). It may also be administered into the eye (intracamerally) by an ophthalmologist prior to an eye surgery after diluting the medicine properly using an ophthalmic irrigating solution to cause pupil dilation.

Q: Can VASOCON INJECTION cause an increase in heart rate?

A: Yes. VASOCON INJECTION is known to increase heart rate and is used to restore your heart rate during emergency conditions like cardiac failure.

Q: Can VASOCON INJECTION cause high blood pressure?

A: Yes. VASOCON INJECTION can be used to increase blood pressure in patients suffering from low blood pressure caused due to septic shock. For this reason, it should be used with caution in patients having hypertension. Therefore, inform your doctor before receiving it.

Q: Can VASOCON INJECTION cause dizziness?

A: Yes. VASOCON INJECTION may cause dizziness in some individuals after administration. Try to rest and relax. Avoid driving or operating heavy tools or machines while you are feeling dizzy. Avoid consumption of alcohol. Consult your doctor if your dizziness did not improve.

Q: Is VASOCON INJECTION safe for use during pregnancy?

A: VASOCON INJECTION should be used in pregnant women only if considered necessary by the physician. Therefore, inform your doctor before receiving VASOCON INJECTION if you are pregnant or think you may be pregnant or planning to have a baby.

References

1. KD. Tripathi. Adrenergic Transmission and Adrenergic Drugs. Essentials of medical pharmacology. 8th Edition. 2019. Page – 146-151.

2. Johannes Ring, Prof. Dr. med. Dr. phil, Ludger Klimek, Prof. Dr. med., and Margitta Worm, Prof. Dr. med. Adrenaline in the Acute Treatment of Anaphylaxis. NIH National Library of Medicine, National center for biotechnology information. August 2018] [Accessed on 7th September 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6131363/#:~:text=Adrenaline%2Fepinephrine%20antagonizes%20crucial%20pathogenetic,edema%20in%20the%20upper%20airway

3. Stephen F Kemp, Richard F Lockey and F Estelle R Simons. Adrenaline in the Acute Treatment of Anaphylaxis. NIH National Library of Medicine, National center for biotechnology information. July 2008. [Accessed on 7th September 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3666145/

4. Macarthys Laboratories Limited. Electronic medicines compendium (EMC). [Revised in September 2019]. [Accessed on 7th September 2022] https://www.medicines.org.uk/emc/files/pil.3673.pdf

5. Mercury Pharmaceuticals Ltd. Electronic medicines compendium (EMC). [Revised in November 2018] [Accessed on 7th September 2022] https://www.medicines.org.uk/emc/files/pil.6595.pdf

6. JHP Pharmaceuticals, LLC. U.S. Food and Drug Administration (FDA). [Revised in December 2012] [Accessed on 7th September 2022] https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/204200s000lbl.pdf

7. Par Pharmaceutical, Inc. Dailymed.com. [Revised in January 2019] [Accessed on 7th September 2022] https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=3b7a4364-668d-4eb2-a20c-04adc35aabe4&type=display

Useful Diagnostic Tests

Absolute Eosinophil count
Total IgE

Author Details

Written By Srilekha. R - B.Pharm

Reviewed For Accuracy By Dr. Thamada Manikanta Praveen - MBBS, MD (General Medicine)

Last updated on 01 Mar 2023 | 05:43 PM(IST)