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Introduction About ZYMAXID 0.5% SOLUTION
ZYMAXID 0.5% SOLUTION contains Gatifloxacin which belongs to the group of medicines called Antibiotics. It is used to manage bacterial conjunctivitis caused by strains of aerobic gram-positive bacteria (Ex. Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus mitis group, Streptococcus oralis, Streptococcus pneumoniae) and aerobic gram-negative bacteria (Ex. Haemophilus influenzae).
ZYMAXID 0.5% SOLUTION should be used with caution in pregnant and breastfeeding women as insufficient data is available on this.
ZYMAXID 0.5% SOLUTION is not recommended for children below 1 year of age. Therefore, contact your doctor before using.
The most common side effects of using ZYMAXID 0.5% SOLUTION include worsening of conjunctivitis, eye irritation, dysgeusia and eye pain. Contact your doctor if any of the side effects worsen.
Uses Of ZYMAXID 0.5% SOLUTION
- Used to manage bacterial conjunctivitis
How ZYMAXID 0.5% SOLUTION Works
ZYMAXID 0.5% SOLUTION works by inhibiting DNA gyrase (an enzyme that helps in replication, transcription and repair of bacterial DNA) and topoisomerase IV (an enzyme that helps in portioning of chromosomal DNA during bacterial cell division).
How to use ZYMAXID 0.5% SOLUTION
Always use ZYMAXID 0.5% SOLUTION as advised by your physician. It is for ophthalmic use only. Check the label for directions for use. Your doctor will prescribe the right dose depends on your age, body weight and disease condition.
Side Effects Of ZYMAXID 0.5% SOLUTION
Common
- eye irritation or pain
- dysgeusia (taste disorder)
Uncommon
- conjunctival haemorrhage (tiny blood vessel breaks just underneath the clear surface of your eye)
- dry eye
- eye discharge
- eyelid oedema
- headache
- increased lacrimation
- keratitis (inflammation of the cornea)
- red eye
- papillary conjunctivitis (eyelid gets red, swollen and irritated)
- reduced visual acuity
Rare
- steven-johnson syndrome
Stop using ZYMAXID 0.5% SOLUTION and contact your doctor immediately if you experience any of the following side effects:
- anaphylactic reactions (symptoms include eye allergy and allergic dermatitis, nausea, pruritis and blurred vision)
- angioedema
- blepharitis
- dyspnoea
Warning & Precautions
Pregnancy
There is no proper information about the use of ZYMAXID 0.5% SOLUTION in pregnant women. Consult your doctor before using.
Breastfeeding
There is no proper information about the use of ZYMAXID 0.5% SOLUTION in breastfeeding women. Consult your doctor before using.
Allergy
Do not use ZYMAXID 0.5% SOLUTION if you are allergic to Gatifloxacin or any other components of this medicine.
Others
Use in pediatrics:
Use of ZYMAXID 0.5% SOLUTION is not recommended in children below 1 year of age as the safety and effectiveness in this age group has not been established. Contact your doctor before using.
Interactions
A. Drug-Drug Interactions:
Tell your doctor if you are using or taking any other medicines including prescription, non-prescription and herbal supplements.
Overdosage:
If you accidentally uses too much ZYMAXID 0.5% SOLUTION, contact your doctor immediately.
Synopsis
| Drug | : | Gatifloxacin |
| Pharmacological Category | : | Antibiotics |
| Therapeutic Indication | : | Bacterial Conjunctivitis |
| Dosage Forms | : | Drops, Eye drops, Eye/Ear drops, Ophthalmic solution, Solution, Ointment, tablet, Eye Ointment |
More Information
- Keep ZYMAXID 0.5% SOLUTION out of sight and reach of children
- Store ZYMAXID 0.5% SOLUTION below 25°C
FAQs About ZYMAXID 0.5% SOLUTION
Is ZYMAXID 0.5% SOLUTION safe for use during pregnancy?
ZYMAXID 0.5% SOLUTION should be used with caution in pregnant and breastfeeding women as insufficient data is available on this. Contact your doctor before using.
What are the side effects of ZYMAXID 0.5% SOLUTION?
The most common side effects of using ZYMAXID 0.5% SOLUTION include worsening of conjunctivitis, eye irritation, dysgeusia and eye pain. Contact your doctor if any of the symptoms worsen.
What is ZYMAXID 0.5% SOLUTION used for?
It is used to manage bacterial conjunctivitis caused by strains of aerobic gram-positive bacteria (Ex. Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus mitis group, Streptococcus oralis, Streptococcus pneumoniae) and aerobic gram-negative bacteria (Ex. Haemophilus influenzae).
What is the mechanism of action of ZYMAXID 0.5% SOLUTION?
Gatifloxacin works by inhibiting DNA gyrase (an enzyme that helps in replication, transcription and repair of bacterial DNA) and topoisomerase IV (an enzyme that helps in portioning of chromosomal DNA during bacterial cell division).
References
1. K.D. Tripathi. Sulfonamides, Cotrimoxazole and Quinolones. Essentials of Medical Pharmacology. 7th Edition. 2013. Page 713.
2. Akorn Pharmaceuticals. U.S. Food and Drugs Administration. [Revised in Mar 2022] [Accessed on 7th Nov 2022] https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=14312de6-67d4-4de2-854c-ef764090dd83
3. Allergan. U.S. Food and Drugs Administration. [Revised in Sep 2016] [Accessed on 7th Nov 2022] https://www.rxabbvie.com/pdf/zymaxid_pi.pdf
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