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Introduction About ZINETAC 150MG TABLET
ZINETAC 150MG TABLET contains Ranitidine which belongs to the group of medicines called H2 receptor antagonists. It is used in the management of intestinal, benign and post-operative ulcers. Peptic or intestinal ulcers are open sores that develop on the inside lining of your stomach and the upper part of your small intestine, causing stomach pain.
ZINETAC 150MG TABLET is also used to manage reflux oesophagitis (inflammation of lower food pipe due to backflow of acidic stomach contents) and Zollinger-Ellison Syndrome (small tumour in the first part of your intestine due to excessive gastrin secretion).
Your doctor may occasionally perform tests to make sure ZINETAC 150MG TABLET is working and to manage side effects. Visit your doctor routinely for a check-up.
Avoid smoking during the management with ZINETAC 150MG TABLET, as it may delay healing or worsen the ulcers. Before taking ZINETAC 150MG TABLET, inform your doctor if you have stomach cancer, kidney, lung or immunity problems, porphyria (rare blood disorder) or diabetes.
ZINETAC 150MG TABLET is not recommended for use in pregnant or breastfeeding women unless your doctor finds it essential. For children, your doctor will determine a proper dose depending on your child’s age, body weight and disease condition. Contact your doctor if you experience any side effects or if any of the symptoms worsen.
Uses Of ZINETAC 150MG TABLET
Manage:
- and manages intestinal, benign and post-operative ulcers
- reflux oesophagitis
- Zollinger-Ellison Syndrome
How ZINETAC 150MG TABLET Works
ZINETAC 150MG TABLET contains Ranitidine that works by reducing the amount of acid made by the stomach, which helps relieve pain and also allows healing of an ulcer or reflux disease.
How to use ZINETAC 150MG TABLET
Take ZINETAC 150MG TABLET as advised by your physician. Do not crush or chew it. Swallow ZINETAC 150MG TABLET as whole with a glass of water. Your doctor will decide the right dose and duration of therapy according to your age, body weight and disease condition. Do not stop taking ZINETAC 150MG TABLET unless your doctor advises you to stop.
Side Effects Of ZINETAC 150MG TABLET
Uncommon
- stomach pain
- constipation
- nausea
Rare
- skin rashes
- increase in serum creatinine levels (kidney function test)
- changes in the liver function
Stop taking ZINETAC 150MG TABLET and contact your doctor immediately if you experience any of the following side effects:
- allergic reactions (rash, itching, hives, swelling of the face, lips, tongue or other body parts, chest pain, wheezing or breathing difficulties, feeling faint especially when standing up, unexplained fever)
- kidney problems (changes in the amount and colour of urine you pass leading to back pain, fever, pain when urinating, blood in urine and changes in the blood test)
- pancreatitis (severe stomach pain)
- irregular or slow heartbeat
- change in blood counts (unusual tiredness, breathlessness or tendency to infections or bruising)
- pain or indigestion occurring during management
- beginning to vomit blood or food
- passing black (blood-stained) stools
How To Manage Side Effects
Nausea:
Take ZINETAC 150MG TABLET with or just after meals. Stick to simple meals. Avoid eating oily or spicy foods. If symptom persists, contact your doctor.
Constipation:
Have plenty of fiber rich foods like fresh fruits, vegetables, cereals and drink ample amount of water. Exercise more regularly. If symptom persists, contact your doctor.
Stomach pain:
Try to rest and relax. Eat and drink slowly or try to eat smaller meals in small breaks. Keep a heat pad on your stomach. If symptom persists, contact your doctor.
Skin rash:
Avoid hot showers because hot water can further irritate your skin. Do not scratch the affected area. Use protective clothing when going outdoors. Regularly moisturize your skin. Consult your doctor if your skin rash persists.
Warning & Precautions
Pregnancy
ZINETAC 150MG TABLET is not recommended for use in pregnant women unless considered clearly necessary. Consult your doctor before taking it.
Breastfeeding
ZINETAC 150MG TABLET is not recommended for use in breastfeeding women unless considered clearly necessary. Consult your doctor before taking it.
Driving and Using Machines
ZINETAC 150MG TABLET has no or negligible effect on driving or using any heavy machineries.
Kidney
ZINETAC 150MG TABLET should be taken with caution in patients with kidney problems. Consult your doctor before taking it.
Liver
ZINETAC 150MG TABLET should be taken with caution in patients with liver disease. Consult your doctor before taking it.
Allergy
Do not take ZINETAC 150MG TABLET if you are allergic to Ranitidine or any of the other ingredients of this medicine.
Lungs
ZINETAC 150MG TABLET should be taken with caution in patients with lung disease, cough or chest infection. Consult your doctor before taking it.
Others
Before taking ZINETAC 150MG TABLET, inform your doctor if you:
- have a history of stomach ulcers
- have stomach cancer
- have acute porphyria (a rare genetic condition)
- have diabetes (high blood sugar)
- have problems with your immune system
Use in paediatrics:
Your doctor will prescribe the right dose of ZINETAC 150MG TABLET depending on age, body weight and health condition of your child. Consult your child’s doctor for advice.
Use in geriatrics:
ZINETAC 150MG TABLET should be used with caution in elderly patients (aged above 65 years). Consult your doctor before taking it.
Interactions
A. Drug - Drug interactions:
Before taking ZINETAC 150MG TABLET, inform your doctor if you are taking any of the following medicines:
- medicines used to reduce pain and inflammation (Ex. aspirin, ibuprofen, naproxen)
- lidocaine (used to make you feel insensitive to pain)
- medicines used to manage heart problems (Ex. propranolol, procainamide, n-acetylprocainamide)
- diazepam (used for worrying or anxiety problems)
- phenytoin (used to manage fits)
- theophylline (used to manage breathing problems)
- warfarin (used to manage blood clots)
- glipizide (used to reduce blood glucose levels)
- medicines used to manage HIV infection (Ex. atazanavir, delavirdine)
- gefitinib (used in lung cancer management)
- medicines used to manage fungal and yeast infections (Ex. itraconazole, ketoconazole)
- sucralfate (used to manage intestinal ulcers)
- medicines used to produce sleepiness and drowsiness during surgeries or to manage insomnia (Ex. midazolam, triazolam)
Overdosage:
If you or anyone else accidentally take too much of ZINETAC 150MG TABLET, consult your doctor immediately or visit the nearby hospital.
Synopsis
| Drug | : | Ranitidine |
| Pharmacological Category | : | H2 receptor antagonist |
| Therapeutic Indication | : | Peptic ulcers, reflux oesophagitis,Zollinger-Ellison Syndrome |
| Dosage Forms | : | Tablet, Capsule, Injection, Liquid, Oral solution, Syrup |
More Information
- Keep ZINETAC 150MG TABLET out of reach of children
- Do not store ZINETAC 150MG TABLET above 25°C
FAQs About ZINETAC 150MG TABLET
Q: What is the use of Zinetac 150 mg Tablet?
A: Zinetac 150 mg Tablet is used in the management of stomach ulcers, duodenal ulcers, acidity, heart burn, acid reflux, indigestion, gas and inflammation of esophagus due to acid reflux (reflux oesophagitis).
Q: Can I take Zinetac 150 mg Tablet for gas?
A: Yes. Zinetac 150 mg Tablet can be used for relieving excess gas and indigestion. It works by reducing gastric acid secretion which reduces GI signs like acidity, heart burn, indigestion, gas, etc.
Q: Is Zinetac 150 safe for daily use?
A: Take Zinetac 150 mg Tablet as advised by your physician. It is typically prescribed for not more than 2-12 weeks. Therefore, consult your doctor before using this medicine daily or for a long-term basis.
Q: Can I drink alcohol with Zinetac 150 mg Tablet?
A: Do not drink alcohol while taking Zinetac 150 mg Tablet, as it could increase the effects of alcohol.
Q: Can I take Zinetac 150 Tablet on an empty stomach?
A: Zinetac 150 Tablet can be taken with or without meals.
Q: Can I take Zinetac 150 Tablet twice daily?
A: Zinetac 150 Tablet is usually prescribed twice daily (i.e., morning and at bedtime) to achieve better results. However, your doctor is the right person to suggest a suitable frequency for taking Zinetac Tablet.
Q: Is Zinetac 150 Tab safe for long-term use?
A: Take Zinetac 150 mg Tablet as advised by your physician. It is typically prescribed for not more than 2-12 weeks. Therefore, consult your doctor before using this medicine daily or for a long-term basis.
Q: How long does it take for Zinetac 150 mg Tablet to start working?
A: Zinetac 150 Tablet starts working within 15 minutes from administration. Its efficacy can extend throughout the entire day or night, providing prolonged relief from symptoms.
Q: Does Zinetac 150 Tablet have side effects?
A: Constipation and nausea are common side effects of taking Zinetac 150 mg Tablet. These side effects usually resolve on their own after few days of therapy. However, check with your doctor if they trouble you.
Q: Can we use Zinetac 150 mg Tablet for acid reflux?
A: Yes. Zinetac 150 mg Tablet reduces gastric acid secretion. This action stops problems caused by acid in the food pipe or too much acid in the stomach. Thus, relieves acid reflux or heartburn.
Q: Can I stop taking Zinetac 150 mg Tablet on my own?
A: If you suddenly stop taking Zinetac 150 mg Tablet the symptoms that existed before the management may return. It is always better to consult your physician before stopping the medicine, even if you feel better.
Q: Can I receive Zinetac 150 mg Tablet before an operation?
A: Before undergoing any operation, inform your doctor if you are receiving Zinetac 150 mg Tablet. This is because the doctor or surgeon can give you sedatives and anaesthetics to make you fall asleep before operation and it can interact with Zinetac 150 mg Tablet. Consult your doctor for further queries.
Q: Can Zinetac 150 mg Tablet be used in children?
A: Zinetac 150 mg Tablet can be used in children aged 16 years or older. Children aged below 16 years of age must consult your doctor before taking this medicine.
Q: Can Zinetac 150 mg Tablet be used during pregnancy?
A: There are no adequate and well-controlled studies regarding the use of Zinetac 150 mg Tablet in pregnant women. Therefore, Zinetac 150 mg Tablet should be used during pregnancy only if considered necessary by the physician.
References
1. KD Tripathi. Gastrointestinal Drugs. Essentials of Medical Pharmacology. Eighth Edition, 2019. Page – 698.
2. Morgan KA, Ahlawat R. Ranitidine. NIH: National Library of Medicine, National center of biotechnology Information. StatPearls [Internet]. December 2021. [Accessed on 27th October 2022] https://www.ncbi.nlm.nih.gov/books/NBK532989/
3. Yeomans, N. D., Svedberg, L. E., & Naesdal, J. Is ranitidine therapy sufficient for healing peptic ulcers associated with non-steroidal anti-inflammatory drug use? NIH National Library of Medicine, National center for biotechnology information. Pubmed Central. November 2006. [Accessed on 27th October 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1636688/
4. Accord Healthcare Limited. Electronic Medicines Compendium (EMC). [Revised in August 2014] [Accessed on 27th October 2022] https://www.medicines.org.uk/emc/files/pil.6040.pdf
5. GlaxoSmithKline Bangladesh Limited. Zantac (Ranitidine hydrochloride). [Revised in February 2013] [Accessed on 27th October 2022] https://gskpro.com/content/dam/global/hcpportal/en_BD/PI/Zantac_Tablet_1_03_2019.pdf
6. Apotex Pty Ltd. APO-Ranitidine (Ranitidine hydrochloride tablet). [Revised in March 2019] [Accessed on 27th October 2022] https://media.healthdirect.org.au/medicines/GuildLink_Information/122014/CMI/txcranit10319.pdf
Useful Diagnostic Tests
- Urea breath test
- Upper GI endoscopy
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