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Introduction About Z8 5MG TABLET
Z8 5MG TABLET contains Zolpidem, which belongs to the group of medicines known as Hypnotics. It is used in the short-term management of insomnia (sleeping disorder) in adults (above 18 years of age). The person with insomnia problems may have difficulty in sleeping, staying awake, or staying asleep, waking up too early etc.
Z8 5MG TABLET is not recommended for use in patients who have or had myasthenia gravis (muscle weakness), severe liver diseases, severe breathing problems, sleep apnoea (serious breathing problem while sleeping), psychosis (mental illness), somnambulism (sleepwalking) or abnormal behaviours after taking hypnotic medication in past.
Z8 5MG TABLET should be used with caution in patients suffering from any heart problems which include irregular heartbeat, depression, or any other mental illness, in patients suffering from kidney disease, and in patients who have a history of alcohol and drug abuse.
Z8 5MG TABLET is not recommended for use by pregnant and breastfeeding women. Z8 5MG TABLET is not recommended for use in children below 18 years of age. Z8 5MG TABLET should be used with caution in elderly patients above age 65 years. The common side effects of taking Z8 5MG TABLET are impaired memory, hallucinations, sleeping problems that might get worse, headache, nightmares, nausea, vomiting, feeling drowsy during the day, etc. Consult your doctor immediately if any of your side effects get worse or if you experience abnormal behaviour or develop suicidal thoughts.
Uses Of Z8 5MG TABLET
- Short-term management of Insomnia (sleeping disorder)
How Z8 5MG TABLET Works
Z8 5MG TABLET helps to manage insomnia. It works by increasing the level of a chemical in the brain called GABA, which blocks or slows down the activity of the brain to induce a calming effect.
How to use Z8 5MG TABLET
Take Z8 5MG TABLET as advised by your doctor. Do not crush or chew the medicine while consuming it with water. Your doctor will decide the correct dosage, and duration of the management for you depending on your age, body weight and disease condition.
Side Effects Of Z8 5MG TABLET
Common
- feeling sleepy, dizzy or drowsy
- headache and fatigue or agitation
- poor memory, strange behaviour
- hallucinations, nightmares, depression
- sleeping problems might get worse
- diarrhoea, nausea, vomiting
- abdominal pain
- back pain
- respiratory infections
Uncommon
- excessive sweating
- restlessness, aggressive behaviour, confusion, irritation
- euphoria
- sleepwalking
- lack of concentration, speech problems
- itching or skin rash
- tremor
- blurred vision or double vision
- muscle pain, muscle spasms, weak muscles, neck pain
- change in appetite
- burning or creeping on skin, tingling, pricking, burning sensation, numbness
- changes in liver function tests
Rare
- less awareness of surroundings
- falling injuries (in elderly patients)
- changes in sexual drive
- urticaria
- itchy skin
- visual impairment
- delusions
- cholestasis (a liver condition in which the flow of bile from the liver is stopped
- signs include jaundice, rash, fever, or dark-coloured urine
- infection or injury to liver signs includes skin, eyes discoloration, pain in the abdomen, bloating, severe itching, pale or bloody stools, weakness, nausea, loss of appetite
- changes the way you walk
Stop taking Z8 5MG TABLET and consult your doctor immediately in case you experience any of the following:
- severe allergic reaction such as rash, itching, hives or urticaria, breathing difficulty and swallowing, swelling in throat, tongue, lips, and face
How To Manage Side Effects
Itchy skin:
Avoid taking hot showers as they can irritate the skin. Do not scratch the affected area. Use sunscreen and protective clothing when going outdoors or use unscented moisturizers to soothe and hydrate the skin. Contact your doctor if the itching persists.
Headache:
Take rest and relax. Apply a pain-relieving balm on the head if needed. Contact your doctor if your headache does not improve.
Dizziness or drowsiness:
Try to rest and relax. Get enough sleep. Avoid driving or operating machinery if you feel drowsiness or dizziness. Avoid alcohol consumption as it can aggravate dizziness or drowsiness. Contact your doctor if your dizziness or drowsiness worsens.
Stomach pain:
Try to rest and relax. Eat small meals but take them frequently. Keep a heating pad on your stomach. Contact your doctor if the stomach pain does not improve.
Diarrhoea:
Drink plenty of water or fruit juices to keep yourself hydrated. Don’t take any medicine on your own to manage diarrhoea. Contact your doctor if the diarrhoea gets worse.
Warning & Precautions
Pregnancy
Z8 5MG TABLET is not recommended for use by pregnant women as it may harm the development of the baby. Such birth defects include cleft lip, cleft palate, reduced foetal movement and foetal heart rate variability, muscle weakness, low body temperature (hypothermia), difficulty feeding and breathing problems (respiratory depression). Consult your doctor before taking Z8 5MG TABLET.
Breastfeeding
Z8 5MG TABLET is not recommended for use by breastfeeding women as it may pass through breast milk. Consult your doctor before taking Z8 5MG TABLET.
Driving and Using Machines
Do not drive or operate any machines if your feel dizzy, drowsy, sleepy, confused, blurring of vision, or less alert after taking Z8 5MG TABLET. Consult your doctor for advice.
Alcohol
Do not consume alcohol while taking Z8 5MG TABLET as it can cause difficulty in breathing or walking, or put you in a very deep sleep. Consult your doctor before taking Z8 5MG TABLET.
Kidney
Z8 5MG TABLET should be used with caution in patients suffering from kidney disease. Consult your doctor before taking Z8 5MG TABLET.
Liver
Z8 5MG TABLET is not recommended for use in patients with severe liver disease. Consult your doctor before taking Z8 5MG TABLET.
Allergy
Do not take Z8 5MG TABLET if you are allergic to Zopiclone or lactose or other lactose other ingredients in the medicine.
Lungs
Z8 5MG TABLET is not recommended for use in patients suffering from sleep apnoea (severe breathing disorder in sleep) and in patients with severe respiratory disorders or breathing difficulties. Consult your doctor before taking Z8 5MG TABLET.
Heart Disease
Z8 5MG TABLET should be used with caution in patients suffering from heart diseases including slow or uneven heartbeat. Consult your doctor before taking Z8 5MG TABLET.
Others
Z8 5MG TABLET is not recommended for use if you have:
- myasthenia gravis (muscle weakness)
- mental illness or psychosis or depression
Before taking Z8 5MG TABLET, inform your doctor if you have:
- depression and any other mental illness
- drug abuse
- plans to take a blood test to check liver function
- thoughts of harming or killing yourself
- fits
Use in paediatrics:
Z8 5MG TABLET is not recommended for use in children below 18 years of age. Consult your doctor before taking Z8 5MG TABLET.
Use in geriatrics:
Z8 5MG TABLET should be used with caution in patients more than 65 years of age. Consult your doctor before taking Z8 5MG TABLET.
Interactions
A. Drug-Drug interactions:
Before taking Z8 5MG TABLET, inform your doctor if you are taking any of the following medicine:
- antipsychotics such as clozapine, haloperidol, and chlorpromazine (medicines used to manage mental illness)
- antidepressants such as sertraline, venlafaxine, fluoxetine, bupropion, and desipramine (medicines used to manage depression)
- antiepileptics such as phenobarbital, phenytoin, and carbamazepine (medicines used to manage epilepsy)
- anaesthetics (medicines used to cause numbness or awareness)
- chlorphenamine, and promethazine (medicines used to manage hay fever or allergies)
- medicines used to induce calm or reduce anxiety or for managing sleep problems (hypnotics) Ex. diazepam, alprazolam, etc
- St. John’s Wort (a medicine used to manage depression and mood swings)
- skeletal muscle relaxants Ex. baclofen (a medicine used to relax muscles)
- opioids such as codeine, methadone, tramadol, pethidine, oxycodone, and morphine (medicines used for severe pain and cough)
- rifampicin (a medicine used to manage tuberculosis)
- ketoconazole, and itraconazole (medicines used to manage fungal infections)
- clarithromycin, erythromycin, ciprofloxacin (medicines used to manage bacterial infections)
- ritonavir (medicines used to manage HIV infection)
- fluvoxamine (medicines used to manage obsessive-compulsive disorder)
Overdosage:
If you or anybody else accidentally take too much Z8 5MG TABLET, consult your doctor or visit the nearest hospital immediately. Symptoms of overdose are drowsiness, confusion, sleeping deeply and possibly falling into a coma.
Synopsis
| Drug | : |
Zolpidem |
| Pharmacological Category | : |
Hypnotic |
| Therapeutic Indication | : |
Manages Insomnia |
| Dosage Forms | : |
Tablet |
More Information
- Keep Z8 5MG TABLET out of reach from children
- Store at room temperature below 25°C
FAQs About Z8 5MG TABLET
Can I take Z8 5MG TABLET every night?
Always take Z8 5MG TABLET as recommended by your doctor. It can be taken before going to bed. Your doctor will decide the correct dosage and duration for you depending on your age, body weight, and severity of your condition.
Can Z8 5MG TABLET affect my blood test results?
Yes, Z8 5MG TABLET can affect your blood sugar levels. Always inform your doctor about the medication you are taking, before taking any blood tests.
Can Z8 5MG TABLET induce abnormal behaviour and suicidal thoughts?
Yes, Z8 5MG TABLET can cause abnormal behaviour and develop suicidal thoughts. Consult your doctor immediately if you develop any behavioural or mental abnormalities.
What are the side effects caused by Z8 5MG TABLET?
Z8 5MG TABLET may cause some side effects such as poor memory, hallucinations, sleeping problems might get worse, headaches, nightmares, nausea, vomiting, feeling drowsy during the day etc. Consult your doctor immediately if any of your side effects get worse.
Is Z8 5MG TABLET a sleeping pill?
Yes, Z8 5MG TABLET is used to induce sleep. It helps to manage patients suffering from insomnia. However, consult your doctor before taking Z8 5MG TABLET.
Can Z8 5MG TABLET cause memory loss?
Yes, Z8 5MG TABLET may cause memory loss and difficulty to concentrate. Contact your doctor if you get any symptoms.
References
1. KD Tripathi. Drugs Acting on Central Nervous System. Essentials of pharmacology, 7th edition. 2013. page 406.
2. Daniel Bouchette, Hossein Akhondi, Judy Quick. Zolpidem. National Institute of Health. NLM. National Centre for Biotechnology Information. Statpearls. May 2022. [Accessed on 29th August 2022] https://www.ncbi.nlm.nih.gov/books/NBK442008/
3. Amber N. Edinoff, Natalie Wu, Yahya T. Ghaffer, Rosemary Prejean, Rachel Gremellion, Mark Cogburn, Azem A. Chami, Adam M. Kaye, Alan D. Kaye. Zolpidem: efficacy and side effects for insomnia, Health Psychology Research, June 2018. [Accessed on 29th August 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8567759/
4. Cynthia K Kirkwood, Jason Neill, Ericka Breden. Zolpidem modified release in insomnia. Neuropsychiatric disease and treatment, November 2007. [Accessed on 29th August 2022] https://www.researchgate.net/publication/24214332_Zolpidem_modified-release_in_insomnia
5. Sanofi Winthrop Industrie. Electronic Medicines Compendium (EMC). [Revised in July 2021] [Accessed on 29th August 2022] https://www.medicines.org.uk/emc/files/pil.3975.pdf
6. Medreich PLC. Health Product Regulatory Authority. [Revised in March 2021] [Accessed on 29th August 2022] https://www.hpra.ie/img/uploaded/swedocuments/676ed5b1-c08a-43ea-908c-207d031ecf1d.pdf
7. Sanofi-Aventis. Zolpidem. [Revised in October 2020] [Accessed on 29th August 2022] https://apps.medicines.org.au/files/swpsticr.pdf
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