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Introduction About Z CILI T TABLET
Z CILI T TABLET is used in adults to manage essential hypertension (high blood pressure. It works by relaxing blood vessels, making it easier for the heart to pump blood. By lowering blood pressure, it reduces the risk of serious complications such as heart attacks and strokes.
Z CILI T TABLET can be taken with or without food, but it is best to take it at the same time each day as directed by your doctor. The dosage will depend on your medical condition and response to the treatment. It is important to continue taking Z CILI T TABLET even if you feel fine, as it helps lower the risk of long-term complications. For better results, complement the therapy with lifestyle changes such as regular exercise, quitting smoking, and following a low-salt, low-fat diet.
Before starting this medicine, inform your doctor if you have any kidney or liver issues or are severely dehydrated. Pregnant or breastfeeding women should also seek medical advice before use. Regular monitoring of blood pressure and kidney function may be necessary during treatment to ensure the medication is working effectively.
Z CILI T TABLET is not recommended for use in patients with severe liver impairment, advanced aortic stenosis (narrowing of the valve in the large blood vessel branching off the heart (aorta) and primary aldosteronism.
The most common side effects of taking Z CILI T TABLET are swelling in the ankles or feet (edema), headache, dizziness, sleepiness, fatigue, changes in taste, and stomach upset. Since it may cause dizziness, avoid driving or performing tasks that require focus until you know how it affects you. If side effects persist or cause discomfort, consult your doctor.
Uses Of Z CILI T TABLET
- It is used to manage essential high blood pressure (hypertension)
How Z CILI T TABLET Works
Z CILI T TABLET contains a combination of two medicines namely, Cilnidipine and Telmisartan respectively.
- Cilnidipine is a calcium channel blocker that works by blocking calcium entry into the smooth muscle cells of blood vessels. This action relaxes and widens the blood vessels, reducing resistance to blood flow and thereby lowering blood pressure. Additionally, cilnidipine also acts on the nerves controlling blood vessels, reducing stress-related constriction, which further helps to maintain steady blood pressure levels.
- Telmisartan is an angiotensin II receptor blocker (ARB). It inhibits the action of angiotensin II, a hormone that causes blood vessels to constrict and increases blood pressure. By blocking this effect, telmisartan relaxes blood vessels and improves blood flow, effectively lowering blood pressure.
Together, cilnidipine and telmisartan provide a dual mechanism to relax and widen blood vessels, enhancing blood circulation and reducing the risk of heart-related complications like heart attack and stroke.
How to use Z CILI T TABLET
- Take Z CILI T TABLET as advised by your physician.
- Swallow Z CILI T TABLET with a glass of water. Do not crush or chew the medicine.
- This medication can be taken with or without food, but it is important to take it at the same time every day to maintain consistent blood levels.
- Follow your doctor’s instructions regarding the dose and duration of use based on your health condition.
- Do not skip doses or stop taking the medication without consulting your doctor, even if you feel well, as this can lead to a sudden rise in blood pressure.
- Regularly monitor your blood pressure to ensure the medication is working effectively.
- If you miss a dose, take it as soon as you remember unless it is close to the time for your next dose; in such cases, skip the missed dose and continue with your regular schedule.
Side Effects Of Z CILI T TABLET
Like all medicines, Z CILI T TABLET may cause certain side effects in some individuals, although not everybody gets them
Most Common Side Effects of Z CILI T TABLET are:
- Dizziness, headache
- Peripheral edema (swelling of ankles, hands and legs)
- Flushing
- Upper respiratory tract infection including pharyngitis and sinusitis
- Hyperkalaemia (increased potassium levels in the blood)
- Slow heart rate
- Low blood pressure
- Stomach upset
- Back or muscle pain, muscle spasms
- Changes in taste
Stop taking Z CILI T TABLET and contact your doctor immediately if you experience any of the following side effects:
- Anaphylactic reaction
- Angioedema (swelling underneath the skin)
- Acute renal failure
Warning & Precautions
Pregnancy
ContraindicatedZ CILI T TABLET is not recommended for use in pregnant women. Consult your doctor for advice.
Breastfeeding
ContraindicatedZ CILI T TABLET is not recommended for use in breast-feeding women. Consult your doctor for advice.
Driving and Using Machines
Use with CautionDo not drive or handle any machines if you experience dizziness after taking Z CILI T TABLET.
Alcohol
Consult your doctorAvoid consumption of alcohol while taking Z CILI T TABLET as it may cause low blood pressure while standing up from sitting or lying position (orthostatic hypotension).
Kidney
Use with CautionZ CILI T TABLET should be used with caution in patients with chronic renal insufficiency. It should be used with caution in patients with impaired kidney function, bilateral renal artery stenosis or stenosis of the artery to a single functioning kidney. Consult your doctor before taking it.
Liver
Consult your doctorZ CILI T TABLET is not recommended for use in patients with severe liver impairment, cholestasis, biliary obstructive disorders. It should be used with caution in patients with mild to moderate liver impairment and elevated liver enzymes. Consult your doctor before taking it.
Allergy
ContraindicatedDo not take Z CILI T TABLET if you are allergic to Telmisartan, Cilnidipine or calcium channel antagonists such as amlodipine, nifedipine.
Heart Disease
Consult your doctorZ CILI T TABLET is not recommended for use in patients with advanced aortic stenosis. It should be used with caution in patients with aortic or mitral stenosis, obstructive hypertrophic cardiomyopathy, angina, ischaemic cardiopathy or ischaemic cardiovascular disease and congestive heart failure. Consult your doctor before taking it.
Use In Pediatrics
ContraindicatedZ CILI T TABLET is not recommended for use in children and adolescents (aged below 18 years). Consult your child’s doctor for advice.
Use In Geriatrics
Use with CautionZ CILI T TABLET should be used with caution in elderly patients (aged 65 years and above). Consult your doctor before taking Z CILI T TABLET.
Others
Z CILI T TABLET is not recommended for use if you:
- Primary aldosteronism
Before taking Z CILI T TABLET, inform your doctor if you:
- Volume and/or sodium depletion by diuretic therapy, dietary salt restriction, diarrhoea or vomiting
- Diabetes
- Peripheral edema
- Metabolic acidosis, cellular lysis (such as acute limb ischemia, rhabdomyolysis, extended trauma)
Interactions
A. Drug-Drug interactions:
Before taking Z CILI T TABLET inform your doctor, if you are taking or receiving any of these medicines:
- Angiotensin-converting enzyme (ACE) inhibitors (Ex. enalapril, lisinopril) angiotensin-II receptor antagonists drugs (Ex. losartan, irbesartan), diuretics (Ex. chlorthalidone, torsemide) and aliskiren (used to manage high blood pressure)
- Anti-psychotic drugs such as risperidone, quetiapine (used to manage mental health conditions such as schizophrenia)
- Digoxin, quinidine (used to manage heart problems)
- Lithium, antidepressants such as paroxetine, fluoxetine (used to manage depression)
- Non-steroidal anti-inflammatory drugs such as aspirin or ibuprofen including selective COX-2 inhibitors such as celecoxib (used to manage pain)
- Cyclosporin, tacrolimus (used to manage organ rejection after transplant)
- Potassium supplements, salt substitutes and potassium-sparing medicines (Ex. spironolactone) (used to manage fluid retention without potassium loss in the urine)
- Aldesleukin (used to manage kidney cancer)
- Trimethoprim, rifampicin, erythromycin (used to manage bacterial infection)
- Baclofen (used to manage relax muscles)
- Amifostine (used to protect the kidney from harmful effects of chemotherapy)
- Heparin (used to manage or manage blood clots)
- Phenytoin, barbiturates such as phenobarbital, pentobarbital (used to manage seizures)
- Narcotics such as morphine (used to manage severe pain)
Overdosage:
If you or anyone else accidentally take too much of Z CILI T TABLET, consult your doctor immediately or visit the nearby hospital. Overdosage symptoms of Z CILI T TABLET are low blood pressure, fast or slow heart rate, dizziness, increase in serum creatinine, acute renal failure, excessive peripheral vasodilatation.
Synopsis
| Drug | : | Cilnidipine, Telmisartan |
| Pharmacological Category | : | Calcium channel blockers, Angiotensin II receptor antagonists |
| Therapeutic Indication | : | Hypertension |
| Dosage Forms | : | Tablet |
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FAQs About Z CILI T TABLET
Q: What is Z CILI T TABLET used for?
A: Z CILI T TABLET is a combination medicine used to manage high blood pressure (hypertension). It helps relax and widen blood vessels, making it easier for the heart to pump blood, thus reducing the risk of complications like heart attacks and strokes.
Q: How should I take Z CILI T TABLET?
A: Take Z CILI T TABLET exactly as prescribed by your doctor. Swallow the tablet whole with water, with or without food. It is best to take it at the same time each day for consistent blood pressure control. Do not stop taking it without consulting your doctor, even if you feel well.
Q: What are the possible side effects of Z CILI T TABLET?
A: Common side effects include swelling in the ankles or feet (edema), dizziness, headache, fatigue, nausea, sleepiness, taste changes, and an upset stomach. Most side effects are mild and resolve on their own, but consult your doctor if they persist or worsen.
Q: Can Z CILI T TABLET cause dizziness?
A: Yes, dizziness is a common side effect of Z CILI T TABLET, especially when starting the medication or increasing the dose. To reduce dizziness, avoid sudden movements and get up slowly from sitting or lying positions. Avoid driving, using machineries or performing activities that requires concentration. Talk to your doctor if dizziness worsens or troubles you.
Q: Can I stop taking Z CILI T TABLET once my blood pressure is normal?
A: No, do not stop taking this medication unless advised by your doctor. High blood pressure often has no symptoms, and discontinuing treatment may cause it to rise again, increasing the risk of heart problems.
Q: Is Z CILI T TABLET safe during pregnancy or breastfeeding?
A: Z CILI T TABLET is not recommended during pregnancy, as it may harm the unborn baby. Breastfeeding mothers should also consult their doctor before using this medicine to assess potential risks.
Q: Can I take Z CILI T TABLET with other medications?
A: Inform your doctor about all other medications you are taking, including over-the-counter drugs and supplements. Telma LN 40mg may interact with certain drugs, such as diuretics, NSAIDs, or lithium, which can affect its efficacy or increase side effects.
Q: What precautions should I take while using Z CILI T TABLET?
A: Avoid alcohol, as it may increase dizziness. Inform your doctor if you have kidney or liver problems, severe dehydration, or if you are taking other blood pressure medications. Regularly monitor your blood pressure and kidney function during treatment.
Q: How long does it take for Z CILI T TABLET to show results?
A: The medication may take a few weeks to show full effectiveness. However, you may notice improvements in your blood pressure readings sooner. Continue taking the medicine as prescribed, even if you don’t feel immediate effects.
Q: What lifestyle changes can enhance the effectiveness of Z CILI T TABLET?
A: To complement the treatment, adopt a healthy lifestyle. Exercise regularly, follow a low-sodium and low-fat diet, maintain a healthy weight, quit smoking, and limit alcohol consumption. These measures can help improve blood pressure control and overall heart health.
Q: What to do if I miss to take a dose of Z CILI T TABLET?
A: You should take Z CILI T TABLET immediately when you remember. If it is time for your next dose skip the missed dose and follow your regular dose schedule. Do not double the dose to match up your missed dose.
Q: For how long should I take Z CILI T TABLET?
A: You should continue taking Z CILI T TABLET unless your doctor tells you to stop the medicine. Blood pressure medicines will be usually taken for lifetime to manage complications due to high blood pressure. Your doctor may change management with other hypertensive drug, if you do not attain effective therapeutic outcome with Z CILI T TABLET.
References
1. KD. Tripathi. Antianginal and other Anti-ischaemic Drugs & Drugs Affecting Renin Angiotensin System. Eighth edition. June 2018. Page – 596 & 536.
2. C Venkata S Ram, Baby Shalini Muppalla, Sarvepalli Vijaya Parthasaradhi, Gajjela Praveen Kumar, Saumitra Ray, Uday Jadhav, J P S Sawhney, Govindan Unni, Nagaraj Desai, Members of the TelCom Study Group. Achieving the Latest American Heart Association and American College of Cardiology Therapeutic Goals for Hypertension With Combination Therapy and Its Effects on Blood Pressure and Central Hemodynamic Parameters. NIH National Library of Medicine. National Centre for Biotechnology Information. Pubmed.gov. April 2022. [Accessed on October 21st 2022] click here
3. Torrent Pharmaceuticals Ltd. Telsar N (Telmisartan and Cilnidipine Tablets). [Revised in April 2020] [Accessed on October 21st 2022] click here
4. Leogenic healthcare. CiniLeo T 10/40 (Cilnidipine and Telmisartan Tablets). [Accessed on October 21st 2022] click here
5. Pure & Cure Healthcare Pvt. Ltd. Cilacar T (Cilnidipine and Telmisartan Tablets). January 2020. [Accessed on October 21st 2022] click here
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