Pfizer Ltd

Wytrol Capsule 15'S

Supplements
MRP ₹288.75 (Inclusive of all taxes)
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    Introduction About WYTROL CAPSULE

    WYTROL CAPSULE is a combination of Calcitriol, Calcium Carbonate, Folic Acid,  Methylcobalamin, and Pyridoxine which belongs to the group of medicines called Vitamin D analogues, Minerals, and B vitamins. It is used to manage, manage, or manage osteoporosis.

    Osteoporosis is a condition that causes thinning and weakening of bones because of excessive absorption of calcium from the bones. It is characterized by symptoms such as bleeding gums, weak grip strength, brittle fingernails, loss of height, frequent fractures, and neck and back pain.

    WYTROL CAPSULE is not recommended for use if you are allergic to calcitriol or any other metabolite of vitamin D, such as alfacalcidol and cholecalciferol. It is also not recommended for use if you have high levels of calcium in your blood, metastatic calcification (extra deposits of calcium in your body), or are not well because of high levels of vitamin D in your body.

    WYTROL CAPSULE is also not recommended for use in patients with renal calculi (kidney stones) or who have a history of renal calculi. Before taking this medicine, inform your doctor if you are suffering from a liver impairment, renal impairment, or other kidney diseases.

    WYTROL CAPSULE should be used with caution in pregnant and breastfeeding women. It should be used with caution in children (under 12 years of age) and elderly patients (aged 65 or above). Consult your doctor before taking it.

    The common side effects associated with the use of WYTROL CAPSULE are constipation, nausea, and vomiting. Contact your doctor or a nearby hospital if any of the conditions worsen.

    Uses Of WYTROL CAPSULE

    • Manage, manage osteoporosis

    How WYTROL CAPSULE Works

    WYTROL CAPSULE helps in managing bone weakening, where calcitriol plays a very important role in aiding the absorption of calcium by acting on certain gut cells to increase the production of calcium transport proteins, whereas calcium carbonate acts by directly increasing the calcium stores in the body.

    Folic acid, pyridoxine, and methylcobalamin work by binding to certain bone-depleting amino acids (homocysteine), which results in the inactivation of those amino agents and an increase in bone-depositing activity in the body, thereby reversing the osteoporotic process.

    How to use WYTROL CAPSULE

    Take WYTROL CAPSULE as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.

    Side Effects Of WYTROL CAPSULE

    Common

    • nausea
    • vomiting
    • constipation

    Rare

    • signs of allergic reactions such as itchy skin, skin rashes, and reddening of the skin
    • signs of changes in kidney function such as nausea, vomiting, and abdominal pain
    • signs of an increase in blood calcium levels such as loss of appetite, weight loss, nausea, vomiting, headache, sluggishness, drowsiness, weakness
    • signs of very high levels of blood calcium levels such as high fever, feeling thirsty, dehydration, passing more water than normal, wetting the bed, constipation, stomach pain, blockage of the bowel, an uneven heartbeat, infections in the bladder, stoppage of normal growth

    Stop taking WYTROL CAPSULE and contact your doctor if you experience any of the following side effects:   

    • signs of severe allergic reactions such as itchy skin, skin rashes, and reddening of the skin

    How To Manage Side Effects

    Constipation

    Try to eat more high-fibre foods, such as fresh fruit, vegetables, and cereals, and drink plenty of water. Try doing exercise regularly (going for a daily walk or run). If this does not help, inform your doctor about receiving alternate managements for constipation.

    Nausea And Vomiting

    Try to take WYTROL CAPSULE with or just after a meal or a snack. Stick to simple meals. Avoid eating rich or spicy food. Consult your doctor if the symptom gets worse.

    Warning & Precautions

    Pregnancy

    Use with Caution

    WYTROL CAPSULE should be used with caution if you are pregnant, think you are pregnant or plan to get pregnant. Consult your doctor before taking it.

    Breastfeeding

    Use with Caution

    WYTROL CAPSULE should be used with caution in breastfeeding women as it passes through the milk. Consult your doctor before taking it.

    Driving and Using Machines

    Safe

    WYTROL CAPSULE is not likely to affect your being able to drive or use any tools or machines.

    Kidney

    Consult your doctor

    WYTROL CAPSULE is not recommended for use in patients with Ca renal calculi (kidney stones) or who have a history of renal calculi. It should be used with caution in patients with renal impairment or other kidney problems. Consult your doctor before taking it.

    Liver

    Use with Caution

    WYTROL CAPSULE should be used with caution in patients with liver impairment. Consult your doctor before taking it.

    Allergy

    Contraindicated

    WYTROL CAPSULE is not recommended for use if you are allergic to Calcitriol, other vitamin D metabolites (including alfacalcidol and cholecalciferol), or any of the other ingredients of this medicine. Consult your doctor before taking it.

    Use In Pediatrics

    Use with Caution

    WYTROL CAPSULE should be used with caution in children (below 12 years). Consult your doctor before taking it.

    Use In Geriatrics

    Use with Caution

    WYTROL CAPSULE should be used with caution in elderly patients (above 70 years). Consult your doctor before taking it.

    Others

    WYTROL CAPSULE is not recommended for use if you:

    • have high blood calcium levels
    • have metastatic calcification (extra deposits of calcium in your body)
    • are not well because of high levels of vitamin D in your body

    Before taking WYTROL CAPSULE, inform your doctor if you:    

    • are immobilized due to operation or any other reason

    Interactions

    A. Drug-Drug Interactions:

    Before taking WYTROL CAPSULE, inform your doctor, if you are taking any of the following medicine:

    • other medicines containing vitamin D
    • diuretics or water tablets (a medicine used to manage high blood pressure) Ex. bendroflumethiazide, chlortalidone, indapamide
    • digoxin or digitoxin (a medicine used to manage heart diseases)
    • medicines containing magnesium such as antacids (medicines used to manage indigestion) Ex. magnesium hydroxide
    • laxatives (medicines used to manage constipation) Ex. bisacodyl
    • corticosteroids (medicines used to manage pain and inflammation) Ex. hydrocortisone, prednisolone, dexamethasone
    • medicine used to manage high levels of blood cholesterol such as ion-exchange resins  Ex. cholestyramine
    • phosphate (a medicine used to manage certain urinary tract infections)

    B. Drug-Food Interactions:

    Avoid eating food which is rich in vitamin D (dairy products like milk and cheese) or has added vitamin D while taking WYTROL CAPSULE. Consult your doctor before taking it.

    Overdosage:

    If you or anyone else accidentally takes too much of WYTROL CAPSULE, consult your doctor immediately or visit the nearby hospital. Symptoms of overdosage are loss of appetite, weight loss, nausea, vomiting, constipation, headache, sluggishness, drowsiness, or weakness.

    Synopsis

    Drug :   Calcitriol, Calcium Carbonate, Folic Acid, Methylcobalamin, and Pyridoxine
    Pharmacological Category :   Vitamin D analogs, Minerals, and B vitamins
    Therapeutic Indication :   Manage osteoporosis
    Dosage Forms :   Tablet, Capsule, Softgel Capsule

    More Information

    • Keep the medicine out of reach of children
    • Store WYTROL CAPSULE at room temperature

    FAQs About WYTROL CAPSULE

    Q: What is WYTROL CAPSULE used for?

    A: WYTROL CAPSULE is used to manage, manage, or manage osteoporosis, a condition that causes thinning and weakening of bones because of excessive absorption of calcium from the bones. It is characterized by symptoms such as bleeding gums, weak grip strength, brittle fingernails, loss of height, frequent fractures, and neck and back pain.

    Q: What happens if you take more WYTROL CAPSULE than your required dose?

    A: If you or anyone else accidentally takes too much WYTROL CAPSULE, consult your doctor immediately or visit the nearby hospital. Symptoms of overdosage are loss of appetite, weight loss, nausea, vomiting, constipation, headache, sluggishness, drowsiness, or weakness.

    Q: What side effects are seen with WYTROL CAPSULE?

    A: The common side effects associated with the use of WYTROL CAPSULE are constipation, nausea, and vomiting. Contact your doctor or a nearby hospital if any of the conditions worsen.

    Q: Who should avoid taking WYTROL CAPSULE?

    A: WYTROL CAPSULE is not recommended for use if you are allergic to calcitriol or any other metabolite of vitamin D, such as alfacalcidol and cholecalciferol. It is also not recommended for use if you have high levels of calcium in your blood, metastatic calcification (extra deposits of calcium in your body), or are not well because of high levels of vitamin D in your body. It is also not recommended for use in patients with calcium renal calculi (kidney stones) or who have a history of renal calculi.

    Q: Is WYTROL CAPSULE safe to use in children or elderly patients?

    A: WYTROL CAPSULE should be used with caution in children (aged below 12 years) and elderly patients (aged above 70 years). Consult your doctor before taking WYTROL CAPSULE.

    Q: How does WYTROL CAPSULE work?

    A: WYTROL CAPSULE helps in managing bone weakening, where calcitriol plays a very important role in aiding the absorption of calcium by acting on certain gut cells to increase the production of calcium transport proteins, whereas calcium carbonate acts by directly increasing the calcium stores in the body.

    Folic acid, pyridoxine, and methylcobalamin work by binding to certain bone-depleting amino acids (homocysteine), which results in the inactivation of those amino agents and an increase in bone-depositing activity in the body, thereby reversing the osteoporotic process.

    Q: Is WYTROL CAPSULE safe for use by pregnant and breastfeeding women?

    A: WYTROL CAPSULE should be used with caution if you are pregnant, think you are pregnant or plan to get pregnant. It should also be used with caution in breastfeeding women. Consult your doctor before taking WYTROL CAPSULE.

    Q: Is WYTROL CAPSULE safe to use in liver patients?

    A: WYTROL CAPSULE should be used with caution in patients with liver impairment (complete or partial loss of liver function, resulting in the accumulation of toxins in the body). Consult your doctor before taking WYTROL CAPSULE.

    Q: Is WYTROL CAPSULE safe to use in kidney patients?

    A: WYTROL CAPSULE is not recommended for use in patients with renal calculi (kidney stones) or who have a history of renal calculi. It should be used with caution in patients with renal impairment or other kidney problems. Consult your doctor before taking WYTROL CAPSULE.

    Q: What if I forget to take my WYTROL CAPSULE dose?

    A: If you forgot to take your WYTROL CAPSULE dose, take it as early as possible. Do not double up the dose to make up for the forgotten one. Consult your doctor before taking WYTROL CAPSULE.

    References

    1. KD Tripathi. Drugs Affecting Calcium Balance. Essentials of medical pharmacology. Seventh edition. 2013. Page 341.

    2. Meghan Meehan, Sue Penckofer. The Role of Vitamin D in the Aging Adult. NIH National Library of Medicine. National Centre for Biotechnology Information. PMC PubMed Central. December 2014. [Assessed on 17th September 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4399494/

    3. Atnahs Pharma UK Limited. Electronic Medicines Compendium (EMC). [Revised in March 2022] [Assessed on 17th September 2022] https://www.medicines.org.uk/emc/files/pil.11802.pdf

    4. Dailymed. Calcium Carbonate 500 MG Chew Tablet. [Revised in October 2021] [Assessed on 17th September 2022] https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=322f1b54-abe9-11a7-e054-00144ff8d46c

    5. Wiscon Pharmaceutical Pvt. Ltd. BONE C PLUS. [Assessed on 17th September 2022] https://wisconpharma.com/products

    6. Emenox Healthcare. Calsonic Plus Capsules. [Assessed on 17th September 2022] https://www.emenoxhealthcare.com/prescription/calsonic-plus-capsules/

    Useful Diagnostic Tests

    • Blood tests
    • Urine analysis

    Author Details

    Written By Dr. Dhivakaran R - BDS
    Reviewed For Accuracy By Dr. Shruthi Raikar - BDS
    Last updated on 22 Mar 2023 | 05:55 PM(IST)
    Lab updated