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Introduction About WELHART 50 CAPSULE
WELHART 50 CAPSULE contains Mexiletine which belongs to the group of medicines called Anti-arrhythmic agents. WELHART 50 CAPSULE is used in the management of irregular heartbeat which is considered to be life threatening in affected individuals.
WELHART 50 CAPSULE is not recommended for use in patients allergic to Mexiletine, and/or local anesthetics. It is also not recommended for use in patients suffering from heart problems (such as sinus syndrome, heart rhythm disorder, long QT syndrome), severe liver, and/or sever kidney disease.
Before taking WELHART 50 CAPSULE, inform your doctor if you are a smoker, and/or have low/high electrolyte blood levels, seizures, abnormal blood count levels, mild to moderate liver or kidney disease.
WELHART 50 CAPSULE is not generally recommended for use in pregnant women and is advised to be used with caution in breastfeeding women as it can pass through breast milk.
WELHART 50 CAPSULE is also not recommended for use in children and adolescents (aged below 18 years) and is advised to be used with caution in elderly patients (aged 65 years/above) after consulting the doctor.
The most common side effects of taking WELHART 50 CAPSULE are abdominal pain, indigestion, nausea, constipation, headache, dizziness, and/or tiredness. Consult your doctor if any of these symptoms worsens.
Uses Of WELHART 50 CAPSULE
- Manage life threatening irregular heartbeats (arrhythmias) in affected individuals
How WELHART 50 CAPSULE Works
WELHART 50 CAPSULE works by blocking abnormal electrical signal in the heart which leads to regulation of heartbeats and managing the occurrence of irregular heartbeat thus managing arrythmias and its associated symptoms in affected individuals.
How to use WELHART 50 CAPSULE
Take WELHART 50 CAPSULE as advised by your physician. Swallow the medicine with water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.
Side Effects Of WELHART 50 CAPSULE
Common
- dry mouth, abdominal pain, dyspepsia (indigestion), nausea, constipation
- insomnia (difficulty sleeping)
- involuntary shaking (tremor), ataxia (difficulty in coordinating movements)
- somnolence (sleepiness)
- headache, dizziness
- tingling/pain in the arms and legs, numbness
- blurred vision
- vertigo (spinning sensation), ringing in the ears
- chest discomfort, rapid heart rate, racing heartbeat, abnormal heart rhythm, low blood pressure
- tiredness, weakness, malaise (feeling discomfort and illness)
- flushing, rash, acne
Uncommon
- convulsions, speech disorders¸ memory loss, loss of consciousness
- hiccups
- loss of hair
- joint pain
- dry skin
- slow heart rate
- erectile dysfunction
Rare
- heart failure
Stop taking WELHART 50 CAPSULE and contact your doctor immediately if you experience any of the following side effects:
- signs of severe allergic reactions such as severe rash, fever
- disorders of heart rhythm associated with signs such as faster/slower heart beats, feeling fluttering/pain in chest, difficulty in breathing, dizziness, sweating, and/or fainting
How To Manage Side Effects
Dry mouth:
Try to drink plenty of cold water and sip on cold unsweetened drinks and use lip balm if your lips are dry. Brush your teeth twice a day and use mouthwash. Consult your doctor if the symptom worsens.
Indigestion:
Try to have smaller and more frequent meals and drink slowly. Reduce consumption of coffee, cola, tea, or alcohol and lose weight if you are obese. Try to avoid smoking and don’t have rich, fatty or spicy foods. Consult your doctor if the symptom does not improve.
Nausea:
Take WELHART 50 CAPSULE with or just after a meal. Stick to simple meals. Avoid eating oil rich or spicy foods, sugary snacks and drinks. Avoid drinking too much liquid along with your meals, drink slowly in between meals. Consult and inform your doctor if the condition worsens.
Constipation:
Try to eat high-fiber foods such as vegetables, cereals, fresh fruit, and drink plenty of water. Involve in regular exercise (going for a daily walk or run) and if this does not help, consult and inform your doctor for receiving alternate managements for constipation.
Headache:
If WELHART 50 CAPSULE causes headache, then take rest and drink plenty of fluids. Try to avoid drinking alcohol. Ask your doctor to recommend a painkiller. Headaches should usually go away after the first week of taking WELHART 50 CAPSULE. If it lasts more than a week or severe, inform your doctor.
Dizziness:
Try to rest and get enough sleep. Try to avoid driving or operating any tools or machines while you feel dizzy. Limit consumption of alcohol, as it can aggravate dizziness. Consult and inform your doctor if the symptom worsens.
Tiredness:
Make sure you take rest and drink plenty of fluids. Avoid or limit the consumption of alcohol. Try to take WELHART 50 CAPSULE at a time when you can sit down (or lie down) when the symptoms are at their worst. Avoid driving or using tools or machinery until you feel well.
Warning & Precautions
Pregnancy
WELHART 50 CAPSULE is not recommended for use in pregnant women. Consult your doctor before taking the medicine.
Breastfeeding
WELHART 50 CAPSULE should be used with caution in breastfeeding women as it can pass through breast milk. Consult your doctor before taking the medicine.
Driving and Using Machines
Do not drive/operate machines if WELHART 50 CAPSULE affects your ability to drive/operate machines.
Alcohol
Avoid consumption of alcohol while taking WELHART 50 CAPSULE since it may alter the effect of medicine. Consult your doctor before consuming alcohol while in management with WELHART 50 CAPSULE.
Kidney
WELHART 50 CAPSULE is not recommended for use in patients with severe kidney disease. It should be used with caution in patients with mild/moderate kidney disease. Consult your doctor before taking the medicine.
Liver
WELHART 50 CAPSULE is not recommended for use in patients with severe liver disease. It should be used with caution in patients with mild/moderate liver disease. Consult your doctor before taking the medicine.
Allergy
Do not take WELHART 50 CAPSULE if you are allergic to Mexiletine, local anesthetics, and/or any other ingredients of this medicine.
Heart Disease
WELHART 50 CAPSULE is not recommended for use in patients suffering from sinus syndrome, other heart problems (known to cause slow heartbeat), heart rhythm disorders (associated with shortness of breath, ankle swelling), and long QT syndrome. Consult your doctor before taking the medicine.
Others
Before taking WELHART 50 CAPSULE, inform your doctor if you:
- have low/high electrolyte blood levels
- suffer from seizures (fits)
- have abnormal blood counts
- have a genetic problem with an enzyme in your body called CYP2D6 (type of enzyme responsible for breaking down certain medicines in the body slowly)
- are a smoker or have quit smoking
Use in Pediatrics:
WELHART 50 CAPSULE is not recommended for use in children and adolescents (aged below 18 years). Consult your doctor before taking WELHART 50 CAPSULE.
Use in Geriatrics:
WELHART 50 CAPSULE should be used with caution in elderly patients (aged 65 years/above). Consult your doctor before taking WELHART 50 CAPSULE.
Interactions
A. Drug-Drug interactions:
Before taking WELHART 50 CAPSULE, inform your doctor if you are taking any of the following medicine:
- medicines used to manage heart problems (Ex. quinidine, procainamide, disopyramide, ajmaline, encainide, flecainide, propafenone, moricizine, amiodarone, sotalol, ibutilide, dofetilide, dronedarone, vernakalant, lidocaine, tocainide, propranolol, esmolol, timolol, metoprolol, atenolol, carvedilol, bisoprolol, nebivolol, verapamil, diltiazem, propafenone, quinidine, dofetilide)
- opioids (used to manage severe pain)
- antacids (used to provide relief from the symptoms of gastroesophageal reflux disease)
- atropine (used to manage certain types of nerve agent and pesticide poisonings)
- metoclopramide (to manage nausea & vomiting)
- drugs that make urine more acidic (Ex. renacidin)
- ciprofloxacin (used to manage bacterial infections)
- fluvoxamine (antidepressant used to manage depression)
- omeprazole (used to manage stomach ulcer and gastric acid reflux)
- phenytoin (used to manage fits)
- rifampicin (used to manage several types of bacterial infections)
- theophylline (used to manage asthma)
- caffeine (used to manage headache, obesity)
- tizanidine (used as a muscle relaxant)
- metformin (used to manage diabetes)
- warfarin (used to manage blood clots)
B. Drug-Food interaction:
It is recommended to reduce your caffeine intake by half while on management with WELHART 50 CAPSULE since it can increase caffeine levels in your blood which may result in unwanted heart problems. Consult your doctor before taking the medicine.
Overdosage:
If you or anyone else accidentally take too much of WELHART 50 CAPSULE, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose are nausea, hypotension (low blood pressure), bradycardia (slow heartbeat), paresthesia (tingling of the extremities), hallucinations, convulsions, irregular heartbeat, and/or fainting.
Synopsis
| Drug | : | Mexiletine |
| Pharmacological Category | : | Anti-arrhythmic agents |
| Therapeutic Indication | : | Life threatening irregular heartbeats (arrythmias) |
| Dosage Forms | : | Capsule |
More Information
- Keep WELHART 50 CAPSULE out of reach of children
- Do not store WELHART 50 CAPSULE above 30°C
FAQs About WELHART 50 CAPSULE
What is WELHART 50 CAPSULE and for what purpose is it used?
WELHART 50 CAPSULE contains Mexiletine which belongs to the group of medicines called Anti-arrhythmic agents which is generally used to manage irregular heartbeat that occurs as a life-threatening condition in affected individuals.
What are the most common side effects of WELHART 50 CAPSULE?
The most common side effects of taking WELHART 50 CAPSULE are abdominal pain, indigestion, nausea, constipation, headache, dizziness, and/or tiredness. Consult your doctor if any of these symptoms worsens.
How WELHART 50 CAPSULE works?
WELHART 50 CAPSULE works by blocking abnormal electrical signal in the heart which leads to regulation of heartbeats and managing the occurrence of irregular heartbeat thus managing arrythmias and its associated symptoms in affected individuals.
How WELHART 50 CAPSULE should be taken?
Take WELHART 50 CAPSULE as advised by your physician. Swallow the medicine with water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.
Can WELHART 50 CAPSULE be used in pregnant and breastfeeding women?
No, WELHART 50 CAPSULE is generally not recommended for use in pregnant women as it can cause harm to the unborn child. It should be used with caution in breastfeeding women since the medicine may pass through breast milk. Consult your doctor before taking the medicine.
References
1. KD Tripathi. Antiarrhythmic Drugs. Essentials of medical pharmacology. Seventh Edition. 2013. Page –531.
2. M L Datta-Chaudhari, T D O'Brien. Prophylactic use of mexiletine in the elderly with acute myocardial infarction. NIH National Library of Medicine. National Center for Biotechnology Information. PubMeg.gov. February 1990. [Accessed on 1st June 2022] https://pubmed.ncbi.nlm.nih.gov/2199424/
3. CANA AE FARMAKEFTIKA ERGASTIRIA. Electronic Medicines Compendium (EMC). [Revised in August 2021] [Accessed on 1st June 2022] https://www.medicines.org.uk/emc/files/pil.13304.pdf
4. Tas med (India) Private Limited. Welhart. [Accessed on 1st June 2022] https://tasmedlab.com/allproduct/welhart/
Useful Diagnostic Tests
- Electrocardiogram
- Stress test/exercise stress test
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