Vymada 200mg Tablet 7'S

Introduction About VYMADA 200MG TABLET

VYMADA 200MG Tablet is a prescription medicine that combines Sacubitril and Valsartan, belonging to the class of angiotensin receptor-neprilysin inhibitors (ARNI). It is recommended for patients with chronic heart failure (NYHA Class II–IV) with reduced ejection fraction to help lower the chances of cardiovascular death and hospital admissions. By improving heart function and reducing stress on the heart, VYMADA 200MG Tablet supports better long-term outcomes in individuals already on standard heart failure therapies.

VYMADA 200MG Tablet can be taken with or without food, preferably at the same time each day for consistent results. The dosage and frequency will be decided by your doctor based on your health condition and response to the medicine. It is important to continue taking the tablet regularly as prescribed and avoid missing doses to achieve the best outcomes. Do not discontinue the medication on your own, even if you feel better, as ongoing use helps maintain heart function and lowers the chances of future health risks.

Common side effects of VYMADA 200MG Tablet may include low blood pressure (hypotension), changes in kidney function, increased potassium levels (hyperkalemia), cough, nausea, and dizziness. To minimize dizziness linked with a drop in blood pressure, rise slowly when moving from a sitting or lying position. Inform your doctor if any of these side effects persist, become bothersome, or if you notice other unusual symptoms.

Before using VYMADA 200MG Tablet, inform your doctor if you are taking any medicines for blood pressure, heart conditions, kidney problems, or liver disorders. Share a complete list of your ongoing medications, as some may interact with this tablet. VYMADA 200MG Tablet should not be used during pregnancy and is not recommended while breastfeeding. During therapy, your doctor may suggest regular monitoring of blood pressure, kidney function, and overall health status to ensure safe and effective use.

Uses Of VYMADA 200MG TABLET

• Chronic heart failure (NYHA Class II–IV) with reduced ejection fraction
• Reduces the risk of cardiovascular death in heart failure patients
• Lowers the chances of hospitalization due to heart failure
• Supports improved heart function and long-term outcomes when used along with standard heart failure medicines

Benefits of VYMADA 200MG TABLET

01)Supports Heart Function: VYMADA 200MG Tablet helps the heart pump more efficiently by easing the workload on the heart and improving blood circulation.

02)Lowers Risk of Hospitalization: Regular use under medical supervision reduces the chances of being admitted to the hospital due to worsening heart failure.

03)Reduces Cardiovascular Risk: By aiding in long-term heart health, this medicine helps lower the likelihood of cardiovascular complications in patients with chronic heart failure.

04)Improves Quality of Life: With better heart performance, individuals may experience improved stamina, reduced fatigue, and enhanced daily activity levels.

05)Works Alongside Standard Therapy: Designed to be used along with other heart failure medications for better overall results and management of the condition.

06)Suitable for Long-Term Use Under Doctor’s Advice: Safe for ongoing use when monitored by a healthcare professional, ensuring stable heart and circulatory health.

How VYMADA 200MG TABLET Works

VYMADA 200MG Tablet combines Sacubitril and Valsartan to support heart health by enhancing natural protective pathways and reducing excessive strain on the heart.

ARNI Technology in Vymada

As an angiotensin receptor–neprilysin inhibitor (ARNI), VYMADA 200MG Tablet brings together the dual actions of blocking harmful effects of angiotensin II and boosting beneficial heart-protective peptides.

Sacubitril and Valsartan Effects

• Sacubitril increases levels of natriuretic peptides, promoting vasodilation and easing fluid overload.
• Valsartan blocks angiotensin II receptors, helping arteries relax and lowering the stress on the heart.

How Vymada Supports Heart Function

By reducing excessive pressure, improving circulation, and helping the heart pump more effectively, VYMADA 200MG Tablet contributes to better overall cardiac performance.

Natriuretic Peptides and Heart Health

Natriuretic peptides are natural body chemicals that widen blood vessels, reduce fluid buildup, and improve cardiovascular balance. VYMADA helps enhance their action, contributing to improved heart efficiency.

Role of Neprilysin Inhibition in Cardiac Care

Neprilysin normally breaks down natriuretic peptides. Sacubitril inhibits neprilysin activity, allowing these peptides to stay active longer and provide continuous cardiovascular support.

How to use VYMADA 200MG TABLET

Directions for Use of VYMADA 200MG Tablet

• Take VYMADA 200MG Tablet with or without food, preferably at the same time each day to maintain steady effects.
• Swallow the tablet whole with water without crushing, chewing, or breaking it.

VYMADA 200MG Tablet Dosage Information

• The usual target dose is 200 mg twice daily, but your doctor will adjust the dose based on your health status and response.
• Starting doses may be lower and gradually increased to the target dose as tolerated.
• Dosage adjustments may be necessary for kidney or liver conditions.

How to Take VYMADA 200MG Tablet

• Follow your doctor’s instructions carefully regarding timing, dose, and duration.
• Do not stop or skip doses without medical advice, even if symptoms improve.

Dosing Schedule and Missed Dose Advice

• Take the tablet consistently, approximately 12 hours apart if prescribed twice daily.
• If a dose is missed, take it as soon as you remember unless it is near the time for the next dose. Do not double the next dose.

Administration Precautions

• Inform your doctor of all medications and health conditions before starting VYMADA.
• Avoid alcohol intake during management.
• Use caution if you experience dizziness or drowsiness, especially when driving or operating machinery.

Important Dosage Adjustments and Safety

• Dose changes may be required under medical supervision for patients with kidney or liver impairment or symptoms like low blood pressure, high potassium, or kidney problems.
• Regular monitoring of blood pressure and kidney function is advised during therapy.

What to Discuss Before Starting VYMADA

• Share your complete medical history with your doctor, especially if you have kidney or liver issues, low blood pressure, or a history of swelling (angioedema).
• Inform if you are pregnant, planning pregnancy, or breastfeeding, as the medicine is not recommended in these cases.

Side Effects Of VYMADA 200MG TABLET

Common:

• Low blood pressure (hypotension)
• Changes in kidney function
• Increased potassium levels (hyperkalemia)
• Cough
• Nausea
• Dizziness

When to consult your doctor?

• Severe allergic reactions symptoms such as swelling of the face, lips, tongue, or throat which may cause difficulty breathing or swallowing (angioedema)
• Sudden fainting or severe dizziness
• Signs of very low blood pressure such as weakness, confusion, or rapid heartbeat
• Signs of hyperkalemia such as muscle weakness, irregular heartbeat, or palpitations
• Significant reduction in kidney function indicated by reduced urine output or swelling in legs and feet

How To Manage Side Effects

Dizziness Or Drowsiness

• Sit or Lie Down: If you feel dizzy, sit down, or lie down immediately to reduce falling. Keep your head still and close your eyes if needed.
• Hydrate: Dehydration can cause dizziness, so drink water or electrolyte-replenishing drinks like sports drinks.
• Avoid Sudden Movements: When standing or sitting, do so slowly to avoid triggering dizziness. Take your time when getting up.
• Eat Small, Regular Meals: Low blood sugar can cause dizziness, so eat small meals throughout the day and avoid skipping meals.
• Fresh Air: Sometimes dizziness can be alleviated by taking slow, deep breaths in a well-ventilated area.

Nausea And Vomiting

• Stay Hydrated: Sip fluids slowly, such as water, ginger tea, or clear soups to support hydration and reduce discomfort.
• Eat Small, Bland Meals: Choose light foods like crackers, toast, or plain rice to minimize stomach irritation.
• Avoid Strong Odors and Spicy Foods: These can worsen feelings of nausea and should be limited during symptoms.
• Rest and Relaxation: Rest in a comfortable position and avoid sudden movements to calm the digestive system.
• Seek Medical Advice: Consult a healthcare provider promptly if nausea is severe, persistent, or accompanied by vomiting.

Warning & Precautions

Pregnancy

Contraindicated

VYMADA 200MG Tablet is not recommended during early pregnancy and must not be taken after 3 months of pregnancy, as it can cause serious harm to the unborn baby. Always consult your doctor if you are pregnant or planning pregnancy before using this medicine.

Breastfeeding

Contraindicated

VYMADA 200MG Tablet is not advised for women who are breastfeeding. Speak to your doctor for alternative options if you are currently breastfeeding or planning to start.

Driving and Using Machines

Use with Caution

Avoid driving, operating machinery, or engaging in tasks requiring alertness while taking VYMADA 200MG Tablet, as it may cause dizziness or excessive tiredness.

Kidney

Use with Caution

VYMADA 200MG Tablet should be used carefully in patients with severe kidney problems or narrowed kidney arteries. Regular medical advice and monitoring are essential before use. Consult your doctor before taking it.

Liver

Consult your doctor

VYMADA 200MG Tablet is not recommended for patients with severe liver disease and should be used cautiously in those with mild to moderate liver problems. Consult your doctor before taking it.

Allergy

Contraindicated

Do not take VYMADA 200MG Tablet if you are allergic to sacubitril or valsartan, or any other ingredients of this medicine.

Use In Pediatrics

Contraindicated

VYMADA 200MG Tablet is generally not recommended for children and adolescents below 18 years of age. Always consult a pediatric doctor for safe alternatives.

Use In Geriatrics

Use with Caution

Elderly patients above 65 years should take VYMADA 200MG Tablet with caution, as dose adjustment and regular monitoring may be required. Consult your doctor before starting the medicine.

Other Warnings for VYMADA 200MG TABLET

Before taking VYMADA 200MG TABLET inform your doctor if you have:

• Low blood pressure or a history of sudden drop in blood pressure.
• Frequent vomiting or diarrhoea
• Dehydration
• Mental health issues such as hallucinations, paranoia, or noticeable changes in sleep patterns

Who should not take [GBNKEYWORD

VYMADA 200MG TABLET is not recommended for use, if you have:

• Diabetes

Diet and Lifestyle Advice

Drug - Drug interaction

1. ACE Inhibitors (e.g., Enalapril, Lisinopril, Ramipril)
   Interaction: Taking VYMADA 200MG Tablet with ACE inhibitors may increase the risk of severe side effects like angioedema (swelling of face, lips, throat).
   Effects: Can cause swelling and difficulty breathing, along with low blood pressure.
   Management: Avoid simultaneous use. Wait at least 36 hours after stopping an ACE inhibitor before starting VYMADA and vice versa. Consult your doctor.
2. Aliskiren (Blood Pressure Medicine)
   Interaction: Combining VYMADA with aliskiren is contraindicated in patients with diabetes or kidney impairment.
   Effects: Increased risk of low blood pressure, high potassium levels, and kidney damage.
   Management: Do not use together if you have diabetes or kidney issues. Inform your doctor.
3. Angiotensin Receptor Blockers (e.g., Telmisartan, Losartan)
   Interaction: Using another ARB with VYMADA may excessively lower blood pressure.
   Effects: May cause dizziness, fainting, weakness.
   Management: Avoid co-administration. Seek medical advice for suitable alternatives.
4. Potassium Supplements and Potassium-Sparing Diuretics (e.g., Spironolactone)
   Interaction: VYMADA may increase potassium levels, leading to hyperkalemia. Using with potassium supplements or sparing diuretics adds to this risk.
   Effects: Muscle weakness, irregular heartbeat, or serious heart problems.
   Management: Regular monitoring of potassium blood levels is essential. Adjust or avoid potassium intake as advised by your doctor.
5. Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) (e.g., Ibuprofen, Indomethacin, Celecoxib)
   Interaction: NSAIDs can reduce the blood pressure-lowering effect of VYMADA and worsen kidney function.
   Effects: Possible kidney damage, increased blood pressure, fluid retention.
   Management: Use NSAIDs cautiously with medical supervision. Routine kidney function tests are recommended.
6. Lithium (Used in Psychiatric Disorders)
   Interaction: VYMADA may increase lithium levels in the blood, raising the risk of lithium toxicity.
   Effects: Symptoms like tremors, confusion, seizures.
   Management: Lithium blood levels should be monitored closely. Dose adjustments may be necessary.
7. Warfarin and Heparin (Blood Thinners)
   Interaction: No significant direct interaction but close monitoring required due to potential changes in kidney function altering drug effects.
   Effects: Risk of bleeding if kidney function worsens.
   Management: Regular blood tests to monitor coagulation and kidney function during combined use.
8. Ritonavir (HIV Medication)
   Interaction: Ritonavir may affect the metabolism of VYMADA, altering its blood levels.
   Effects: Increased risk of side effects or reduced effectiveness of VYMADA.
   Management: Dosage adjustments and close monitoring by your healthcare provider are advised.

Drug - Food interaction

1. Potassium-Rich Foods (e.g., Bananas, Broccoli, Oranges)
   Interaction: VYMADA 200MG Tablet may increase potassium levels in the blood. Consuming potassium-rich foods along with VYMADA can raise potassium excessively.
   Effects: High potassium may cause muscle weakness, irregular heartbeat, or serious heart complications.
   Management: Avoid excessive intake of potassium-rich foods and potassium supplements while on VYMADA. Regular blood potassium monitoring is advised.
2. Alcohol
   Interaction: Drinking alcohol with VYMADA may intensify side effects like dizziness and low blood pressure.
   Effects: Increased risk of light-headedness, fainting, and impaired alertness.
   Management: Limit or avoid alcohol consumption during management with VYMADA to reduce these risks.
3. Salt Substitutes Containing Potassium
   Interaction: Using salt substitutes with potassium while taking VYMADA can further increase potassium levels.
   Effects: Risk of hyperkalemia with symptoms such as heart palpitations or muscle cramps.
   Management: Avoid potassium-based salt substitutes; discuss alternatives with your doctor.
4. High Sodium (Salt) Diet
   Interaction: A high-sodium diet may reduce the effectiveness of VYMADA in controlling blood pressure.
   Effects: Poor blood pressure control, increased risk of heart failure symptoms.
   Management: Maintain a low-sodium diet as advised by your healthcare provider for best results.

Synopsis

More Information

VYMADA 200mg vs Similar Medications: Why Choose VYMADA?

VYMADA stands out primarily due to its clinically proven effective combination of sacubitril and valsartan for heart failure, its cost-effectiveness compared to brand-name options, and trusted manufacturing quality backed by awards and certifications. It provides comprehensive heart failure management by improving heart function and reducing hospitalization risk, which some alternatives may lack or offer less effectively.

FAQs About VYMADA 200MG TABLET

Q: What is VYMADA 200mg Tablet used for?

A: VYMADA 200mg Tablet is used to reduce the risk of cardiovascular death and hospitalization in adults with chronic heart failure with reduced ejection fraction by improving heart function and easing blood flow

Q: How does VYMADA 200mg Tablet work?

A: VYMADA 200mg Tablet combines sacubitril and valsartan. sacubitril relaxes blood vessels and increases beneficial peptides while valsartan blocks angiotensin II to reduce blood vessel tightening, together improving heart pumping efficiency.

Q: What are the common side effects of VYMADA 200mg Tablet?

A: Common side effects include dizziness, low blood pressure, cough, headache, tiredness, nausea, muscle weakness, and changes in kidney function. Contact your doctor if symptoms worsen.

Q: Who should avoid taking VYMADA 200mg Tablet?

A: Pregnant or breastfeeding women, children under 18, patients with severe liver disease, or history of angioedema with similar drugs should avoid VYMADA 200mg Tablet

Q: How should VYMADA 200mg Tablet be taken?

A: Take VYMADA 200mg Tablet exactly as prescribed by your doctor, usually twice daily, swallowing the tablet whole with water, with or without food.

Q: Can I take VYMADA 200mg Tablet with other medications?

A: Inform your doctor about all medications you are currently taking to avoid harmful interactions, especially with potassium supplements or other blood pressure medicines.

Q: What precautions should be taken while on VYMADA 200mg Tablet?

A: Avoid sudden position changes to reduce dizziness, monitor blood pressure and kidney function regularly, and avoid potassium-rich foods or supplements unless advised by your doctor.

Q: Is VYMADA 200mg Tablet suitable for elderly patients?

A: It can be used with caution in elderly patients aged 65 and above, under medical supervision to monitor side effects and dosage.

Q: How to buy VYMADA 200mg Tablet online safely from Netmeds?

A: Visit the official Netmeds website, search for VYMADA 200mg Tablet, upload a valid doctor’s prescription during checkout, choose a secure payment method, and provide an accurate delivery address. Netmeds will verify your prescription before processing the order to ensure you receive genuine medication safely at your doorstep.

References

1. KD Tripathi MD. Cardiovascular drugs. Essentials of Medical Pharmacology. Seventh Edition. New Delhi, May 2013. Page-508.

2. Loretta Fala. Entresto (Sacubitril/Valsartan): First-in-Class Angiotensin Receptor Neprilysin Inhibitor FDA Approved for Patients with Heart Failure. NCBI; PMC. Pubmed Central. National Library of Medicine, National Institute of Health. September 2018. [Accessed on 29th Sep 2025] 

3. Peter Khalil, Ghazal Kabbach, Sarmad Said and Debabrata Mukherje. Entresto, a New Panacea for Heart Failure. NIH National Library of Medicine, National center for biotechnology information. Pubmed.gov. 2018. [Accessed on 29th Sep 2025] 

4. Novartis Pharmaceuticals UK Ltd. Electronic Medicines Compendium (EMC) [Revised in May 2021] [Accessed on 29th Sep 2025] 

Useful Diagnostic Tests

• Kidney Function Test with Electrolytes (KFT / RFT)
• Liver Function Test (LFT)
• Metabolic Profile-Basic
• Complete Blood Count (CBC)

Author Details

Written By Dr. Janet.C - Pharm.D

Reviewed For Accuracy By Dr. Thamada Manikanta Praveen - MBBS, MD (General Medicine)

Last updated on 10 Jul 2024 | 03:54 PM(IST)