New Revised MRP, 100% GST benefit passed UTREVA Gel 1.125gm
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Introduction About UTREVA GEL
UTREVA GEL is a vaginal gel used in females to manage female infertility due to incorrect levels of progesterone during the menstrual cycle or when you are having an assisted fertility procedure.
It contains a medicine called Progesterone which is a synthetic female hormone. When the gel is inserted into your vagina, the progesterone will slowly release into your bloodstream throughout the day which mimics the actions of natural progesterone produced in your body.
UTREVA GEL is for vaginal use only. Gently insert the gel using the applicator into the vagina. Wash your hands before and after application. Before using this medicine, inform your doctor if you have any liver, kidney or heart problems, asthma, diabetes, epilepsy, unexplained vaginal bleeding, migraine or history of depression as a precaution.
UTREVA GEL is not recommended for use in breastfeeding women. It is normally not suggested during pregnancy, unless you have used this medicine to help become pregnancy. The most common side effects of using UTREVA GEL are breast tenderness, stomach cramps, pelvic pain, pain around genital area, vaginal discharge or itching, low sex drive, and sleepiness. Consult your doctor if they trouble you.
Talk to your doctor if you experience breast enlargement and pain after using this medicine.
Uses Of UTREVA GEL
- Female Infertility
How UTREVA GEL Works
UTREVA GEL contains progesterone which is a synthetic form of naturally occurring female sex hormone. Upon application into the vagina, it slowly releases the medicine and mimic as a natural progesterone which is required in maintaining optimum uterine thickness for egg implantation and maintenance of pregnancy in the early stages.
How to use UTREVA GEL
- Use UTREVA GEL under medical supervision
- Wash your hands thoroughly with soap and water.
- UTREVA GEL usually comes with a pre-filled applicator. Take the required amount of the medicine into the gel applicator
- Lie on your back with your knees bent or stand with one foot elevated, whichever is more comfortable for you.
- Gently insert the gel using the applicator into your vagina, pushing it as far as comfortable.
- Slowly press the plunger to release the gel into the vagina.
- Remove the applicator and discard it if it’s disposable or wash it with soap and water if it’s reusable.
- Wash your hands again after the application.
- Follow your doctor’s instructions regarding the timing and frequency of use.
Side Effects Of UTREVA GEL
Common Side Effects of UTREVA GEL:
- Breast tenderness
- Abdominal pain or cramps, Bloating, Constipation
- Pain around genital and anal areas
- Vaginal discharge, itching or infection
- Headache
- Low sexual drive, painful sexual intercourse
- Sleepiness, feeling emotional
- Constipation, nausea
- Passing urine at night
- Joint pain
Stop using this medicine and inform your doctor immediately if you experience any of the following reactions:
- Allergic reactions (such as severe skin rashes with itching and swelling of face, lips, tongue, throat causing breathing difficulties)
- Depression
- Breast enlargement or breast pain
Warning & Precautions
Pregnancy
ContraindicatedProgesterone gels are not normally used in pregnant women. However, if you have used this medicine to help become pregnant, you may be told by your physician to continue using it to support the early stages of pregnancy.
Breastfeeding
ContraindicatedProgesterone vaginal gels are not recommended for use in breastfeeding women.
Driving and Using Machines
Use with CautionUTREVA GEL has no influence on driving or using machinery.
Kidney
Use with CautionUTREVA GEL should be used with caution in patients with kidney diseases.
Liver
Use with CautionUTREVA GEL should be used with caution in patients with liver diseases.
Allergy
ContraindicatedDo not use UTREVA GEL if you are allergic to progesterone or any other ingredients of this medicine.
Lungs
Use with CautionThis medicine should be used with caution in patients with history of asthma.
Heart Disease
Use with CautionThis medicine should be used with caution in patients with heart diseases.
Use In Pediatrics
ContraindicatedThis medicine is not suitable for use in children and adolescents aged below 18 years.
Others
UTREVA GEL is not recommended for use if you:
- Have unexplained vaginal bleeding
- Have porphyria
- Think you might have breast cancer or cancers in your reproductive organs
- Have ever had a blood clot due to swollen veins (thrombophlebitis), a blocked blood vessel (thromboembolic disorder) or a stroke
Before using this medicine, inform your doctor if you:
- Have diabetes
- Have epilepsy
- Often get migraine headache
- Have ever had depression
Interactions
A. Drug-Drug interactions:
Before taking UTREVA GEL, inform your doctor if you are taking any of the following medicines:
- Other vaginal preparations
Overdosage:
If you or anyone else accidentally used too much of UTREVA GEL, consult your doctor immediately or visit the nearby hospital.
Synopsis
| Drug | : | Progesterone |
| Pharmacological Category | : | Progestins (female hormones) |
| Therapeutic Indication | : | Female infertility |
| Dosage Forms | : | Tablet, Softgel Capsule, Pessaries, Injection, Vaginal Gel, Vaginal spray |
More Information
FAQs About UTREVA GEL
Q: What is UTREVA GEL used for?
A: This medicine is commonly used to support fertility treatments, regulate menstrual cycles, and help in early pregnancy by providing the hormone progesterone, which is vital for maintaining a healthy uterine lining.
Q: How is UTREVA GEL applied?
A: This medicine is typically applied vaginally using a pre-filled applicator. The gel is inserted directly into the vagina to ensure better absorption and delivery of progesterone.
Q: What are the side effects of UTREVA GEL?
A: Common side effects may include vaginal irritation, discharge, breast tenderness, headaches, mood swings, and dizziness. If side effects persist or worsen, consult a healthcare provider.
Q: How long does progesterone gel stay in your system?
A: The duration can vary, but the gel usually provides a steady release of progesterone over a 24-hour period when applied as instructed.
Q: Can progesterone gel cause weight gain?
A: While progesterone can cause fluid retention and bloating, leading to a temporary increase in weight, significant long-term weight gain is uncommon.
Q: Is progesterone gel safe during pregnancy?
A: Yes, progesterone gel is often prescribed to support early pregnancy and is considered safe when used as directed by a healthcare provider.
Q: Can I use UTREVA GEL during my period?
A: It is generally recommended to follow your doctor's advice regarding usage during menstruation, as it depends on the reason for use (e.g., fertility treatment or hormone replacement).
References
1. KD. Tripathi. Estrogens, Progestins, and Contraceptives. Essentials of Medical Pharmacology. Eighth edition. 2013. Page-340.
2. Progestins. StatPearls. National Center for Biotechnology Information. National Library of Medicine. [Revised in January 2024]. [Accessed on 8th October 2024] click here
3. Progesterone 8% w/w Vaginal Gel. EMC. UK. Merck Serono Ltd. [Revised in December 2020]. [Accessed on 8th October 2024] click here
4. Progesterone. Crinone Vaginal Gel. Consumer Medicine Information. [Accessed on 8th October 2024] click here
5. CRINONE (Progesterone gel) 8%. EMD Inc., Canada. [Revised in July 2023]. [Accessed on 8th October 2024] click here
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