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Introduction About TURBOVAS EZ 10 TABLET
TURBOVAS EZ 10 TABLET is a combination of Ezetimibe and Rosuvastatin which belongs to the group of medicines called Antihyperlipidemic agents. It is used to reduce elevated blood lipid levels (hyperlipidemia) in addition to proper diet, exercise, and lifestyle changes.
By reducing lipid levels in the blood, TURBOVAS EZ 10 TABLET can also be used to manage the risk of heart attack, stroke, atherosclerosis and other circulatory disorders. Along with the management, avoid drinking large amount of alcohol to achieve better results.
Before taking TURBOVAS EZ 10 TABLET inform your doctor if you have any liver or kidney problems. You must also inform your doctor if you have thyroid problems, diabetes, high blood pressure or a family history of muscle disorders.
TURBOVAS EZ 10 TABLET is not recommended for use in patients with severe liver or kidney problems. It is also not suitable for use in patients with severe repetitive unexplained muscle pains or in patients who had recently taken an antibiotic called Fusidic acid to manage bacterial infections.
Do not take TURBOVAS EZ 10 TABLET if you are pregnant or breastfeeding. Women of childbearing potential must use a suitable contraceptive method to avoid pregnancy while undergoing therapy with TURBOVAS EZ 10 TABLET.
The most common side effects of taking TURBOVAS EZ 10 TABLET are headache, constipation, bloating, muscle pain and liver problems. Consult your doctor if they bother you.
Uses Of TURBOVAS EZ 10 TABLET
It is used to:
- Manage high blood cholesterol levels
- Reduces the risk of heart attack, stroke or atherosclerosis
How TURBOVAS EZ 10 TABLET Works
TURBOVAS EZ 10 TABLET is a lipid-lowering medicine. It reduces the levels of bad cholesterol (VLDL and LDL) and triglycerides in the body by blocking the actions of certain enzymes that are involved in lipid metabolism (such as HMG-CoA reductase). Additionally, it can also reduce the amount of cholesterol synthesised by the body.
By lowering the blood lipid levels, TURBOVAS EZ 10 TABLET manages fat deposition within the blood vessels and reduces the chances of heart attack, stroke, atherosclerosis or other circulatory problems.
How to use TURBOVAS EZ 10 TABLET
Take TURBOVAS EZ 10 TABLET as directed by your physician. It can be taken with or without meals. Swallow the medicine with a glass of water. Do not crush or chew the medicine.
Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition. Do not stop taking TURBOVAS EZ 10 TABLET without consulting your doctor.
Side Effects Of TURBOVAS EZ 10 TABLET
Common
- headache, dizziness
- stomach pain, constipation, nausea, diarrhea, flatulence
- muscle pain
- feeling weak
- protein loss in urine
- increased blood sugar levels (diabetes)
- increased liver enzyme levels
Uncommon
- decrease in sex drive
- hair loss
- skin redness and itching
- cough
- indigestion, heartburn, loss of appetite
- joint pain, neck pain, back pain
- high blood pressure
- tingling sensation
- dry mouth
- unusual tiredness or weakness
- swelling, especially in the hands and feet
Rare
Stop taking TURBOVAS EZ 10 TABLET and consult your doctor immediately if you experience any of the following side effects:
- severe allergic skin reactions (such as skin rash, itching, skin redness with blisters or peeling of the skin, swelling in the mouth, which may be associated with high fever and joint pains)
- unexplained muscle pain or weakness, especially if accompanied by fever, weakness or reddish-brown urine
- lupus-like disease syndrome characterized by rash, muscle pain, joint disorders, pain and swelling
- severe allergic reactions (such as swelling of the face, lips, tongue, throat which makes it difficult to swallow or breathe, breathing problems or wheezing, severe dizziness or fainting, rash or hives, itching)
- liver problems symptoms such as feel tired or weak, upper belly pain, yellowing of your skin or the whites of your eyes, loss of appetite, dark urine, nausea, vomiting
How To Manage Side Effects
Constipation
Eat plenty of fiber rich foods such as fresh fruits, vegetables, and cereals. Drink plenty of fluids. Exercise more regularly. Consult your doctor if this side effect bothers you.
Dizziness Or Drowsiness
Try to rest and relax. Get enough sleep. Avoid driving or operating any tools or machines completely while you are feeling dizzy. Do not consume excessive alcohol, as it could aggravate your dizziness. Consult your doctor if your dizziness worsens.
Headache
Rest and relax. Keep yourself hydrated by drinking plenty of fluids such as water or electrolytes. Applying a pain-relieving balm on your forehead can be beneficial. Do not consume excessive alcohol, as it could aggravate your headache. Consult your doctor if your headache worsens.
Nausea And Vomiting
Take TURBOVAS EZ 10 TABLET with or just after a meal or a snack. Stick to simple meals. Avoid eating rich or spicy food. Consult your doctor if your nausea worsens.
Warning & Precautions
Pregnancy
ContraindicatedTURBOVAS EZ 10 TABLET is not recommended for use in pregnant women as it may cause serious harm to the growing foetus. Therefore, inform your doctor before taking it. Women of childbearing potential must use a suitable contraception to avoid pregnancy while undergoing therapy with TURBOVAS EZ 10 TABLET. If you accidentally become pregnant while taking this medicine, stop taking it and consult your doctor immediately.
Breastfeeding
ContraindicatedTURBOVAS EZ 10 TABLET is not recommended for use in breast-feeding women. Therefore, consult your doctor before taking it.
Driving and Using Machines
Use with CautionDo not drive or operate any heavy tools or machines if your ability is affected by TURBOVAS EZ 10 TABLET.
Alcohol
ContraindicatedAvoid consumption of alcohol while taking TURBOVAS EZ 10 TABLET as it may reduce the effectiveness of this medicine.
Kidney
Consult your doctorTURBOVAS EZ 10 TABLET is not recommended for use in patients with moderate to severe kidney problems. It should be used with caution in patients with other mild kidney problems. Therefore, consult your doctor before taking it.
Liver
Consult your doctorTURBOVAS EZ 10 TABLET is not recommended for use in patients with severe liver or gall bladder problems. It should be used with caution in patients with other liver problems. Therefore, consult your doctor before taking it.
Allergy
ContraindicatedDo not take TURBOVAS EZ 10 TABLET if you are allergic to Ezetimibe or Rosuvastatin.
Lungs
Use with CautionTURBOVAS EZ 10 TABLET should be used with caution in patients with respiratory failure. Therefore, consult your doctor before taking it.
Use In Pediatrics
Consult your doctorTURBOVAS EZ 10 TABLET should be used in children and adolescents (aged below 18 years) only if prescribed by the physician. It is not recommended for use in children (aged below 6 years) due to lack of safety data. Therefore, consult your doctor for advice.
Use In Geriatrics
Use with CautionTURBOVAS EZ 10 TABLET should be used with caution in elderly patients. Therefore, consult your doctor before taking it
Others
TURBOVAS EZ 10 TABLET is not recommended for use if you:
- have repeated or unexplainable muscle cramps or pain
- have inflammation of the pancreas
- have problems in thyroid gland (underactive thyroid)
- have a family history of muscular disorder
- previously had any muscle problems while taking similar type of lipid-lowering medicines
- are an alcoholic
Before taking TURBOVAS EZ 10 TABLET, inform your doctor if you:
- have diabetes (type I or type II)
- are obese
- have high blood pressure
- have blood problems
Interactions
A. Drug-Drug Interactions:
Before taking TURBOVAS EZ 10 TABLET inform to your doctor if you are taking any of the following medicines such as:
- medicines used to manage cancer (Ex. actinomycin, regorafenib)
- medicines used to suppress immune system after organ transplantation (Ex. cyclosporin)
- medicines used for blood thinning (Ex. warfarin, acenocoumarol)
- clopidogrel (a medicine used to manage blood clots)
- medicines used to manage bacterial infections (Ex. erythromycin, fusidic acid)
- medicines used to manage HIV and hepatitis C infections (Ex. lamivudine, stavudine, ritonavir, dasabuvir, sofosbuvir, velpatasvir, voxilaprevir, lopinavir, atazanavir)
- medicines used for contraception (Ex. ethinylestradiol)
- medicines used to manage diabetes (Ex. rosiglitazone, pioglitazone)
- other medicines used to manage high lipid levels in blood (Ex. fenofibrate, cholestyramine, colesevelam)
- medicines used for indigestion such as antacids (Ex. aluminium hydroxide)
Overdosage:
If you or anyone else accidentally took more TURBOVAS EZ 10 TABLET, consult your doctor immediately or visit the nearby hospital.
Synopsis
| Drug | : | Ezetimibe, Rosuvastatin |
| Pharmacological Category | : | Sterol absorption inhibitors, HMG-CoA reductase inhibitors |
| Therapeutic Indication | : | High Blood cholesterol |
| Dosage Forms | : | Tablet |
More Information
Storage
- Keep TURBOVAS EZ 10 TABLET out of reach of children
- Store TURBOVAS EZ 10 TABLET at room temperature
FAQs About TURBOVAS EZ 10 TABLET
Q: What are the uses of TURBOVAS EZ 10 TABLET?
A: TURBOVAS EZ 10 TABLET is a lipid lowering medicine. It is used to control elevated blood cholesterol levels in addition to proper diet, exercise and lifestyle changes. By reducing lipid levels in the blood, TURBOVAS EZ 10 TABLET can also be used to manage the risk of heart attack, stroke, atherosclerosis and other circulatory disorders.
Q: Can the use of TURBOVAS EZ 10 TABLET cause diabetes?
A: TURBOVAS EZ 10 TABLET may increase blood sugar levels in some patients. This is seen more predominantly among patients who already have diabetes along with obesity and/or hypertension. Therefore, consult your doctor before taking this medicine if you are diabetic, obese or have hypertension. Your doctor will closely monitor your blood sugar levels while undergoing therapy with TURBOVAS EZ 10 TABLET to avoid any unwanted side effects.
Q: What is the best time to take TURBOVAS EZ 10 TABLET?
A: Take TURBOVAS EZ 10 TABLET as advised by your physician. It can be taken with or without meals. Your doctor will decide the best time for you to take TURBOVAS EZ 10 TABLET. Try to take TURBOVAS EZ 10 TABLET at the same time each day.
Q: What are the side effects of taking TURBOVAS EZ 10 TABLET?
A: The most common side effects of taking TURBOVAS EZ 10 TABLET are pain in joints and muscles, gastrointestinal problems such as constipation, diarrhoea, indigestion or nausea and headache. Contact your doctor if any of side effect worsens. Also, inform your doctor if you experience severe unexplained muscle pain, tenderness, or weakness along with fever after taking this medicine.
Q: Can I consume alcohol along with TURBOVAS EZ 10 TABLET?
A: TURBOVAS EZ 10 TABLET is not recommended for use in patients who consume large amounts of alcohol. It is advisable to avoid alcohol consumption while taking TURBOVAS EZ 10 TABLET to achieve maximum benefits.
Q: Can the use of TURBOVAS EZ 10 TABLET make me feel more tired?
A: Yes. The use of TURBOVAS EZ 10 TABLET can make you feel more tired, because it acts by reducing the supply of energy to the muscles present in your body. However, you may also feel tired due to other reasons such as severe liver damage. Consult your doctor if you experience excessive tiredness with muscle pain.
Q: Who should not take TURBOVAS EZ 10 TABLET?
A: TURBOVAS EZ 10 TABLET is not recommended for use in patients with severe liver or kidney problems. It is also not suitable for use in patients having muscle problems. If you are pregnant or breastfeeding consult your doctor before taking TURBOVAS EZ 10 TABLET. Before taking TURBOVAS EZ 10 TABLET inform your doctor if you have diabetes. Do not take this medicine if you are undergoing therapy with antibiotics such as fusidic acid.
Q: What are the dietary restrictions that I need to follow while taking TURBOVAS EZ 10 TABLET?
A: While taking TURBOVAS EZ 10 TABLET, follow a low-cholesterol diet as instructed by your doctor and avoid excessive alcohol intake. Avoid eating oil rich or deep-fried foods. Limit your sugar intake by avoid eating biscuits, cakes, soft drinks or pastries. Stick to a simple nutritious diet.
Q: What should I do if I forget to take a dose of TURBOVAS EZ 10 TABLET?
A: If you forget to take a dose of TURBOVAS EZ 10 TABLET, take it as soon as you remember. However, if it is time to take the next dose of TURBOVAS EZ 10 TABLET, skip the missed dose and take the next one at regular times. Do not take a double dose of TURBOVAS EZ 10 TABLET to compensate the missed dose, as it could lead to toxicity.
Q: Can I stop taking TURBOVAS EZ 10 TABLET once my blood cholesterol level is controlled?
A: Do not stop taking this medicine without consulting your doctor, as it could once again increase your blood cholesterol levels. TURBOVAS EZ 10 TABLET can only control your blood cholesterol levels and cannot manage them completely, therefore, it is important to take this medicine until your doctor advises you to stop.
Q: Can I take TURBOVAS EZ 10 TABLET if I am diabetic?
A: TURBOVAS EZ 10 TABLET may increase blood sugar levels in some patients. This is most predominantly seen in patients who already have diabetes along with obesity and/or hypertension. Therefore, consult your doctor before taking TURBOVAS EZ 10 TABLET if you are diabetic.
Q: Does TURBOVAS EZ 10 TABLET cause muscle pain?
A: TURBOVAS EZ 10 TABLET may cause a rare but serious side effect of unexplained muscle pain or weakness called rhabdomyolysis. It might be an early sign of a potentially serious muscle degradation. Therefore, consult your doctor if you experience any signs of muscle problems after taking TURBOVAS EZ 10 TABLET. Also, talk to your doctor before taking TURBOVAS EZ 10 TABLET if you already have weak muscles or have a family history of any muscle disorders.
Q: What is TURBOVAS EZ 10 TABLET and what does it do?
A: TURBOVAS EZ 10 TABLET is a lipid-lowering medicine. It reduces the levels of bad cholesterol in the body. Additionally, it can also reduce the amount of cholesterol produced by the body and reduces the chances of heart attack, stroke, atherosclerosis or other circulatory problems.
Q: How long should I take TURBOVAS EZ 10 TABLET to manage high cholesterol?
A: You should take TURBOVAS EZ 10 TABLET as long as your doctor advises you to take. Because TURBOVAS EZ 10 TABLET will only help you in managing your cholesterol levels and cannot completely manage them. If you stop using TURBOVAS EZ 10 TABLET, your cholesterol levels may raise once again.
Q: Can TURBOVAS EZ 10 TABLET be taken by pregnant or breast-feeding women?
A: TURBOVAS EZ 10 TABLET is not recommended for use in pregnant or breast-feeding women. Therefore, consult your doctor before taking it. Women of childbearing age must use a reliable contraceptive method to avoid pregnancy while undergoing therapy with this medicine. However, if you accidentally become pregnant while taking this medicine, stop taking it and consult your doctor immediately.
References
1. KD. Tripathi. Hypolipidaemic Drugs and Plasma Expanders. Essentials of medical pharmacology. Seventh edition. 2013. Page – 637, 641.
2. Maya R Chilbert, Dylan VanDuyn, Sara Salah, Collin M Clark and Qing Ma. Combination Therapy of Ezetimibe and Rosuvastatin for Dyslipidemia: Current Insights. NIH. National Library of Medicine. National Center for Biotechnology Information. PMC. PubMed Central. July 2022. [Accessed on 23rd December 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9273150/
3. Zentiva Pharma UK Limited. Electronic Medicines Compendium (EMC). [Revised in September 2022] [Accessed on 23rd December 2022] https://www.medicines.org.uk/emc/files/pil.8870.pdf
4. Glenmark Pharmaceuticals Europe Limited. Electronic Medicines Compendium (EMC). [Revised in November 2020] [Accessed on 23rd December 2022] https://www.medicines.org.uk/emc/files/pil.9869.pdf
5. SCOV3 LLC. Rosuvastatin and Ezetimibe tablet. Dailymed.com. [Revised in August 2021]. [Accessed on 23rd December 2022] https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=e6e4001e-fa7c-4661-bed4-c22671762d6d
6. Althera Pharmaceuticals LLC. U.S. Food and Drug Administration. [Revised in March 2021]. [Accessed on 23rd December 2022] https://www.accessdata.fda.gov/drugsatfda_docs/label/2021/213072s000lbl.pdf
7. Central Drugs Standard Control Organization. Rosuvastatin calcium eq. to Rosuvastatin 10mg + Ezetimibe 10mg tablets. February 2007. [Accessed on 23rd December 2022] https://cdsco.gov.in/opencms/resources/UploadCDSCOWeb/2018/UploadApprovalNewDrugs/dciApprovedfdc.pdf
Useful Diagnostic Tests
- Cholesterol - HDL
- Cholesterol - LDL
- Cholesterol – Total
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