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Introduction About TRICLEAR N GEL
TRICLEAR N GEL contains a combination of Adapalene and Nadifloxacin, which belongs to the group of medicines called topical retinoids and fluoroquinolone antibiotics. It is used in the management of acne. Acne is a condition of the skin when the root of your hair (hair follicle) or skin pores gets clogged by oil or dead skin, which becomes prone to bacterial infection resulting in pimples, blackheads and spots or scars.
Adapalene is a form of vitamin A, that acts as an antiacne agent by binding directly to the receptor of the skin which increases the rate of cell regeneration and decreases oil secretion managing clogging of the hair follicles and pores. It also reduces swelling/inflammation. Nadifloxacin is an antibiotic, that kills bacteria by suppressing a specific enzyme in their DNA that is necessary for their reproduction and growth. Before recommending TRICLEAR N GEL, your doctor may advise you to undergo tests to understand your existing condition for planning effective management methods. Stay well hydrated and protect your skin from exposure to sunlight or UV light.
Do not apply TRICLEAR N GEL if you are allergic to adapalene or nadifloxacin, or have bruises, cuts or burns on the skin, disease of the digestive system (colitis) or diseases of the immune system. The common side effects of using this medicine may include dry skin, burning, itching, redness or irritative sensation of the skin, scaling peeling of the skin.
Uses Of TRICLEAR N GEL
- To manage acne
How TRICLEAR N GEL Works
Adapalene, a form of vitamin A, works as an antiacne drug by attaching directly to the skin's receptor, which increases cell regeneration and decreases oil secretion managing blockage of the hair follicles and pores. It also reduces swelling/inflammation of the skin. Nadifloxacin kills bacteria by suppressing a specific enzyme in their DNA that is necessary for their reproduction and growth.
How to use TRICLEAR N GEL
Apply TRICLEAR N GEL as advised by your doctor. It is for external use on the skin only. Avoid applying TRICLEAR N GEL around or onto your eyes, including eyelids.
Side Effects Of TRICLEAR N GEL
Common
- dryness of the skin
- burning, itching, redness of the skin
- skin irritation
- scaling and or peeling of the skin
- Redness
- Discoloration of the skin
Uncommon
- flaring of acne
- sunburns
- local skin reaction
Stop using this medicine and contact your doctor immediately if you experience any of the following side effects:
- severe allergic reactions (such as skin rash, itching, swelling of the face, lips, tongue and other parts of the body, difficulty in breathing or wheezing, blisters on the skin, sore throat, fever, headache etc.)
How To Manage Side Effects
Dry Skin
Drink plenty of water and stay well hydrated. Use moisturizer as recommended by your doctor.
Warning & Precautions
Pregnancy
ContraindicatedTRICLEAR N GEL is not recommended for use in pregnant women. Consult your doctor for advice.
Breastfeeding
Use with CautionTRICLEAR N GEL is to be used with caution in breastfeeding mothers only if recommended by your doctor.
Driving and Using Machines
Use with CautionTRICLEAR N GEL may not interfere with your ability to drive or use the machine. However, protect your skin from sun or UV light while travelling and follow appropriate protective measures recommended by your doctor.
Alcohol
Consult your doctorThe risks associated with consuming alcohol are not known. It’s advised to avoid the consumption of alcohol while using TRICLEAR N GEL, as it could aggravate your existing condition.
Allergy
ContraindicatedTalk to your doctor if you are allergic to Adapalene and Nadifloxacin.
Use In Pediatrics
ContraindicatedTRICLEAR N GEL is not recommended for use in children less than 12 years of age. Consult your doctor for advice.
Use In Geriatrics
Use with CautionTRICLEAR N GEL should be taken with caution in the elderly only if recommended by your doctor.
Others
TRICLEAR N GEL is not recommended for use if you have:
- cuts or bruises on the skin
- sunburns
- skin conditions like eczema (itching, dry and red skin)
Before using TRICLEAR N GEL, inform your physician if you have:
- compromised immune system
- disease causing muscle weakness such as myasthenia gravis
- sensitivity to antibiotics followed by severe diarrhea
Interactions
A. Drug-Drug interactions:
Inform your physician, if you are taking or using:
- Medicated soap for skin, other cosmetic products with a high concentration of alcohol, astringents, sulfur etc.
- Resorcinol – used for itching or irritation of the skin and scalp, loss of hair, dandruff etc.
- Salicylic acid – used for skin acne, dandruff, etc.
B. Drug-Food interaction:
The interaction of foods with TRICLEAR N GEL is not known. Consult your doctor for diet advice.
Overdosage:
In case of using TRICLEAR N GEL in excess than recommended, you may experience dryness, scaling, redness and discomfort of the skin. Contact your doctor immediately if the symptoms worsen or persists.
Synopsis
| Drug | : | Adapalene, Nadifloxacin |
| Pharmacological Category | : | Topical retinoids and fluroquinolone antibiotics |
| Therapeutic Indication | : | Manage acne |
| Dosage Forms | : | Gel |
More Information
- Keep out of reach from children
- Store at room temperature.
- Keep away from sunlight
FAQs About TRICLEAR N GEL
Q: Can TRICLEAR N GEL be used for acne?
A: Yes. Adapalene is a form of vitamin A, which decreases swelling, inflammation and increases cell regeneration rate. Nadifloxacin helps to fight against bacterial infection of the skin.
Q: Can TRICLEAR N GEL be used in children?
A: TRICLEAR N GEL is generally not recommended for use in children less than 12 years of age. Consult your doctor for advice.
Q: Can TRICLEAR N GEL cause peeling of skin?
A: Yes. The side effects of using this medicine may include dryness of the skin, burning, itching, redness of the skin, skin irritation, scaling and or peeling of the skin
Q: Can [GBBNKEYWORD] cause dryness of the skin?
A: Yes. This medicine can cause dryness of your skin. Stay hydrated and apply the moisturizer as recommended by your doctor.
Q: How long can I use TRICLEAR N GEL?
A: Use TRICLEAR N GEL as advised by your doctor. Generally, it’s recommended for use depending on the severity of the existing skin condition.
Q: Can I stop using TRICLEAR N GEL on my own?
A: No. It is not recommended to stop using TRICLEAR N GEL on your own as it may worsen the existing skin condition. Consult your doctor for advice.
References
1. KD. Tripathi. Drugs act on skin and mucous membranes & miscellaneous drugs. Essentials of medical pharmacology. 8th Edition. 2019. Page – 953 to 954.
2. Laurence Brunton, Bruce Chabner, Bjorn Knollman. Dermatological Pharmacology. Goodman & Gilman’s The Pharmacological Basis of Therapeutics. 12th Edition. 2006. Page-1809.
3. Aura Rusu, Corneliu Tanase, Georgiana-Andreea Pascu and Nicoleta Todoran. Pharmaceuticals (MBPI). Recent Advances Regarding the Therapeutic Potential of Adapalene. [Revised on 28th August 2020] [Accessed on 29th March 2022] https://www.mdpi.com/1424-8247/13/9/217/pdf
4. Claudia Neumeistera, Rolf-Hasso Bödekerb, Ulrich Schwantesa, Claudia Borellic. Biomedicine Hub. Impact of Parallel Topical Treatment with Nadifloxacin and Adapalene on Acne Vulgaris. [Revised on 24th February 2021] [Accessed on 29th March 2022] https://www.karger.com/Article/Pdf/520447
5. Galderma (UK) Limited. Adapalene. [Revised on March 2021] [Accessed on 26th March 2022] https://www.medicines.org.uk/emc/files/pil.921.pdf
6. Berko Ilaç ve Kimya Sanayi A.S. Aknefloks 1% cream. [Revised on 4th January 2016] [Accessed on 29th March 2022] http://berkoilac.com.tr/wp-content/uploads/2018/08/aknefloks-cream-PIL-revH.pdf
7. Alembic Pharmaceuticals, Inc. National Library of Medicine (NIH). Adapalene gel [Revised on November 2021] [Accessed on 26th March 2022] https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=a3b6f3c3-d615-4b00-a76f-134b75e30a50&type=display
8. Galderma Laboratories, L.P. Adapalene gel. [Revised on February 2018] [Accessed on 26th March 2022] https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=a0031324-92a6-4c11-90e2-c2818f7278ec&type=display
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