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Introduction About TONOFERON SF CAPSULE
TONOFERON SF CAPSULE contains a combination of Ferrous succinate, Folic acid, and Succinic acid that belongs to the group of medicines called Iron salts, Vitamins, and Dicarboxylic acids derivatives respectively. It is used to manage or manage nutritional anaemia due to iron or folate deficiency.
It is also used to manage or manage iron deficiency states or depleted bone marrow iron (ferritin) stores during increased physical growth & physiological demand such as pregnancy, childhood, & adolescence, heavy/chronic blood loss after surgery, bleeding piles, and gynaecological disorders (from menarche to menopause).
It is also used while recovering from chronic illnesses (such as TB, malaria, kidney diseases, & liver diseases) or in old age. Anaemia is a condition in which the red blood cell count decreases abnormally due to deficiency of iron or folic acid or due to excessive blood loss conditions.
TONOFERON SF CAPSULE is not recommended for use in deficiency of vitamin B12, possibly caused by pernicious anaemia or if you have a vegetarian diet. Before using TONOFERON SF CAPSULE, inform your doctor if you are under therapy for a folate-dependent tumour, have a family history of neural tube defects (NTDs), are obese, or have diabetes.
TONOFERON SF CAPSULE should be used with caution in pregnant and breastfeeding women. The most common side effects associated with the use of TONOFERON SF CAPSULE are nausea/vomiting, constipation, diarrhoea, stomach upset. Consult your doctor if any of the symptoms worsens.
Uses Of TONOFERON SF CAPSULE
- It is used to manage or manage nutritional anaemia due to iron or folate deficiency
- It is used to manage or manage iron deficiency states or depleted bone marrow iron (ferritin) stores during periods of increased physical growth & physiological demand
How TONOFERON SF CAPSULE Works
TONOFERON SF CAPSULE helps in replenishing blood in the body where Ferrous succinate and succinic acid work by directly increasing the iron stores in the body, thereby enhancing the synthesis of haemoglobin and myoglobin (oxygen carrying pigment in muscles). Folic acid acts as a vital co-factor in the synthesis of the “heme” (iron) part of haemoglobin.
How to use TONOFERON SF CAPSULE
Take TONOFERON SF CAPSULE as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.
Side Effects Of TONOFERON SF CAPSULE
Common
- nausea/vomiting
- constipation
- diarrhoea
- stomach upset
Rare
Stop taking TONOFERON SF CAPSULE and contact your doctor if you experience any of the following side effects:
- signs of allergic reactions such as skin rash, flaking skin, boils, or sore lips and mouth
- signs of serious allergic reactions such as sudden noisy breathing, fluttering or tightness of the chest or collapse
How To Manage Side Effects
Constipation
Try to eat more high-fibre foods such as fresh fruit, vegetables, cereals, and drink plenty of water. Try doing exercise regularly (going for a daily walk or run). If this does not help, inform your doctor for receiving alternate managements for constipation.
Diarrhea
Drink lots of fluids, such as water to keep yourself hydrated. Try to avoid taking any medicine on your own to manage diarrhoea and consult your doctor if the symptom gets worse.
Nausea And Vomiting
Stick to simple meals. Avoid eating rich or spicy food. Consult your doctor if the symptom gets worse.
Warning & Precautions
Pregnancy
Use with CautionTONOFERON SF CAPSULE should be used with caution in pregnant women or women planning to have a baby. Consult your doctor before taking it.
Breastfeeding
Use with CautionTONOFERON SF CAPSULE should be used with caution in breastfeeding women. Consult your doctor before taking it.
Driving and Using Machines
Use with CautionTONOFERON SF CAPSULE has a negligible effect on your ability to drive or use machines.
Allergy
ContraindicatedTONOFERON SF CAPSULE is not recommended for use if you are allergic to Ferrous Succinate, Folic acid, Succinic Acid or any other ingredients of this medicine. Consult your doctor before taking.
Others
TONOFERON SF CAPSULE is not recommended for use if you:
- have a deficiency of vitamin B12 due to pernicious anaemia
- are in a vegetarian diet
Before taking TONOFERON SF CAPSULE, inform your doctor if you:
- are under management for a folate-dependent tumour
- have a family history of birth defects called neural tube defects
- have diabetes
- are obese
Interactions
A. Drug-Drug Interactions:
Before taking TONOFERON SF CAPSULE, inform your doctor, if you are taking any of the following medicine:
- anti-epileptics (medicines used to manage epilepsy and fits) Ex. phenytoin, phenobarbital, primidone
- antibacterials (medicines used to manage infections) Ex. chloramphenicol, co-trimoxazole
- sulfasalazine (medicines used to manage arthritis or inflammatory bowel disease, including ulcerative colitis or Crohn’s disease)
- methotrexate (medicines used to manage severe active rheumatoid arthritis, severe psoriasis, and certain types of cancer)
Overdosage:
If you or anyone else accidentally takes too much of TONOFERON SF CAPSULE, consult your doctor immediately or visit the nearby hospital. However, intake of folic acid in large doses is unlikely to cause harm.
Synopsis
| Drug | : | Ferrous succinate, Folic acid, and Succinic acid |
| Pharmacological Category | : | Iron salts, Vitamin, and Dicarboxylic acid derivatives |
| Therapeutic Indication | : | Prevention and management of nutritional anaemia, iron deficiency, depleted bone marrow iron (ferritin) |
| Dosage Forms | : | Capsule |
More Information
- Keep the medicine out of reach in children
- Store TONOFERON SF CAPSULE below 25°C
FAQs About TONOFERON SF CAPSULE
Q: What TONOFERON SF CAPSULE is used for?
A: TONOFERON SF CAPSULE is used to manage or manage nutritional anaemia due to iron or folate deficiency. It is used to manage or manage iron deficiency states or depleted bone marrow iron (ferritin) stores during periods of increased physical growth & physiological demand such as pregnancy, childhood, & adolescence, while recovering from chronic illnesses (such as TB, malaria, kidney diseases, & liver diseases), heavy/chronic blood loss after surgery, bleeding piles, gynaecological disorders (from menarche to menopause), etc.
Q: What happens if you take more TONOFERON SF CAPSULE than your required dose?
A: If you or anyone else accidentally takes too much of TONOFERON SF CAPSULE, consult your doctor immediately or visit the nearby hospital. However, intake of folic acid in large doses is unlikely to cause harm.
Q: What side effects are seen with TONOFERON SF CAPSULE?
A: The most common side effects associated with the use of TONOFERON SF CAPSULE are nausea/vomiting, constipation, diarrhoea, stomach upset. Consult your doctor if any of the symptoms worsens.
Q: Who should avoid taking TONOFERON SF CAPSULE?
A: TONOFERON SF CAPSULE is not recommended for use if you are allergic to folic acid or have a deficiency of vitamin B12 due to pernicious anemia or a vegetarian diet. Consult your doctor before taking it.
Q: How TONOFERON SF CAPSULE works?
A: TONOFERON SF CAPSULE helps in replenishing blood in the body where Ferrous succinate and succinic acid work by directly increasing the iron stores in the body, thereby enhancing the synthesis of haemoglobin and myoglobin (oxygen carrying pigment in muscles). Folic acid acts as a vital co-factor in the synthesis of the “heme” part of haemoglobin.
Q: Is TONOFERON SF CAPSULE safe to use in pregnancy and lactation?
A: TONOFERON SF CAPSULE is indicated for use in iron deficiency states or depleted bone marrow iron (ferritin) stores in pregnant women. However it should be used with caution in pregnant and breastfeeding women. Consult your doctor before taking.
References
1. KD. Tripathi. Haematinics and Erythropoietin. Seventh edition. Essentials of medical pharmacology. 2013. Page-603.
2. Minhthao Nguyen, Prasanna Tadi. Iron Supplementation. NIH National Library of Medicine. National Centre for Biotechnology Information. StatPearls [Internet]. July 2022. [Assessed on 16th September 2022] https://www.ncbi.nlm.nih.gov/books/NBK557376/
3. Feng-Zhi Xin, Ze-Hua Zhao, Rui-Nan Zhang, Qin Pan, Zi-Zhen Gong, Chao Sun, Jian-Gao Fan. Folic acid attenuates high-fat diet-induced steatohepatitis via deacetylase SIRT1-dependent restoration of PPARα. NIH National Library of Medicine. National Centre for Biotechnology Information. PMC PubMed Central. June 2020. [Assessed on 16th September 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7235203/
4. Irene Capelli, Giuseppe Cianciolo, Lorenzo Gasperoni, Fulvia Zappulo, Francesco Tondolo, Maria Cappuccilli, Gaetano La Manna. Folic Acid and Vitamin B12 Administration in CKD, Why Not? NIH National Library of Medicine. National Centre for Biotechnology Information. PMC PubMed Central. February 2019. [Assessed on 16th September 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6413093/
5. Parul Christian, Mary E. Morgan, Laura Murray-Kolb, Steven C. LeClerq, Subarna K. Khatry, Barbara Schaefer, Pamela M. Cole, Joanne Katz, James M. Tielsch. Preschool Iron-Folic Acid and Zinc Supplementation in Children Exposed to Iron-Folic Acid in Utero Confers No Added Cognitive Benefit in Early School-Age. NIH National Library of Medicine. National Centre for Biotechnology Information. PMC PubMed Central. September 2011. [Assessed on 16th September 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3192462/
6. E H Reynolds. Folic acid, aging, depression, and dementia. NIH National Library of Medicine. National Centre for Biotechnology Information. PMC PubMed Central. June 2002. [Assessed on 16th September 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1123448/
7. Clonmel Healthcare Ltd. Health Products Regulatory Authority (HPRA). [Revised in January 2019] [Assessed on 16th September 2022] https://www.hpra.ie/img/uploaded/swedocuments/b7d79cb3-6f64-46bd-81da-574bfaa8cba0.pdf
8. Tonoferon-SF. East India Pharmaceutical Works Limited. [Assessed on 16th September 2022] https://eastindiapharma.org/therapies/haematinic/tonoferon-sf/
Useful Diagnostic Tests
- Complete blood count (CBC)
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