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Aristo Pharmaceuticals Pvt Ltd

Telvas Beta 50mg Tablet 10'S

Hypertension
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    Introduction About TELVAS BETA 50MG TABLET

    Telvas Beta 50mg Tablet is a combination medication primarily used for managing high blood pressure (hypertension). It contains two active ingredients: Telmisartan, which relaxes and widens blood vessels by blocking angiotensin II receptors, and Metoprolol Succinate, a beta-blocker that reduces heart rate and decreases the heart's workload. Together, they help lower blood pressure effectively, reducing strain on the heart and blood vessels. This medication is ideal for patients diagnosed with hypertension, especially those needing comprehensive cardiovascular support to lower risks of stroke, heart attack, or kidney complications.

    This medicine is best taken once daily, preferably at the same time each day, with or without food. Patients should swallow the tablet whole with a glass of water without crushing or chewing it. Consistent adherence to the prescribed dosage is crucial for achieving the best long-term benefits. Directions for use include monitoring for dizziness or lightheadedness, particularly when standing up quickly, which may indicate lowered blood pressure.

    Important precautions include avoiding use during pregnancy and breastfeeding due to potential harm to the foetus and infant. Patients with severe liver or kidney dysfunction, allergies to the components, or certain heart and lung conditions should consult their doctor before use. Alcohol consumption is discouraged during treatment, as it can exacerbate side effects like low blood pressure. Elderly patients and those with pre-existing medical conditions should have regular check-ups to monitor therapy effects.

    Common side effects include headache, fatigue, dizziness, slow heart rate, cold extremities, and occasional gastrointestinal discomfort. Most side effects are mild and temporary, but patients should promptly seek medical advice if they experience severe symptoms like chest pain, persistent dizziness, or allergic reactions. Telvas Beta 50mg Tablet offers a well-rounded approach to blood pressure control, supporting cardiovascular health through its dual mechanism of action.

    Uses Of TELVAS BETA 50MG TABLET

    • High blood pressure (Hypertension)

    Benefits of TELVAS BETA 50MG TABLET

    Telvas Beta 50mg for Hypertension

    Telvas Beta 50mg Tablet is commonly prescribed for managing hypertension (high blood pressure). It combines Telmisartan and Metoprolol, which work together to relax blood vessels and reduce heart strain. By lowering blood pressure, it helps decrease the risks linked with uncontrolled hypertension, such as strain on the heart, kidneys, and blood vessels. Doctors may recommend it to patients who need dual therapy for effective blood pressure control. Taking it regularly as advised supports long-term blood pressure management.

    Telvas Beta 50mg for Cardiovascular Support

    Telvas Beta 50mg Tablet also provides cardiovascular support by reducing the workload on the heart and promoting smooth blood circulation. Metoprolol helps control heart rate, while Telmisartan keeps blood vessels relaxed, together easing pressure on the cardiovascular system. This combination supports overall heart health, especially in patients with additional risk factors like irregular heartbeat or high blood pressure. Regular monitoring and medical supervision ensure the best outcomes for cardiovascular well-being.

    How TELVAS BETA 50MG TABLET Works

    Telvas Beta 50mg Mechanism

    Telvas Beta 50mg Tablet works through a dual mechanism as it contains two active ingredients – Telmisartan and Metoprolol. Telmisartan belongs to a group of medicines called angiotensin II receptor blockers (ARBs). It relaxes blood vessels by blocking certain chemicals that tighten them, which makes it easier for blood to flow. Metoprolol is a beta-blocker that lowers heart rate and reduces the workload on the heart. Together, they help maintain healthy blood pressure and support heart function more effectively than single therapy.

    How to use TELVAS BETA 50MG TABLET

    How to Take Telvas Beta 50mg Tablet

    • Take the tablet exactly as prescribed by your doctor.
    • It can be taken with or without food, preferably at the same time every day.
    • Swallow the tablet whole with a glass of water – do not crush or chew it.
    • Follow your doctor’s instructions carefully for safe and effective use.
    • Do not stop taking the medicine suddenly without medical advice.

    Telvas Beta 50mg Dosage Instructions

    • The dosage is decided by your doctor based on your age, health condition, and blood pressure levels.
    • It is usually prescribed once daily, but your doctor may adjust the dose if needed.
    • Do not increase or decrease the dose on your own.
    • If you miss a dose, take it as soon as you remember, but skip it if the next dose is near.
    • Always complete the prescribed course to get the best results.

    What if I forgot to take TELVAS BETA 50MG TABLET

    • If you miss a dose, take it as soon as you remember.
    • If it is almost time for your next dose, skip the missed one and continue with your regular schedule.
    • Do not take two tablets at the same time to make up for the missed dose, as this may cause low blood pressure or slow heartbeat.
    • Try to take the medicine at the same time every day to avoid forgetting.
    • If you frequently miss doses, talk to your doctor for guidance or set reminders.

    Overdose

    An overdose of Telvas Beta 50mg tablet can cause serious symptoms such as severe dizziness, a significant drop in blood pressure, irregular or unusually slow heartbeat, and difficulty breathing. If an overdose occurs, it is critical to seek immediate medical care or contact a poison control centre. Overdosing may lead to life-threatening complications, including heart failure or circulatory collapse, requiring urgent treatment.

    Side Effects Of TELVAS BETA 50MG TABLET

    Common side effects of taking Telvas beta 50mg tablet are:

    • Tiredness
    • Dizziness
    • Depression
    • Shortness of breath
    • Slow heartbeat
    • Low blood pressure
    • Diarrhoea
    • Itchy skin
    • Rash
    • Vertigo (sudden internal or external spinning sensation)
    • Abdominal pain
    • Insomnia or sleep disturbances
    • Muscle cramps

    When to Seek Medical Attention?

    Stop taking Telvas beta 50mg tablet and consult your doctor immediately if you experience any of the following side effects:

    • Sepsis (a life-threatening severe infection occurring due to damage of whole-body immune response)
    • Angioedema (rapid and serious swelling of the skin and mucosa)

    How To Manage Side Effects

    Diarrhea

    • Stay hydrated: Sip water, clear broths, or oral rehydration solutions throughout the day to replace lost fluids and electrolytes.
    • Eat bland foods: Choose gentle options like bananas, rice, applesauce, and toast to ease digestion and reduce irritation.
    • Avoid irritants: Limit caffeine, alcohol, dairy, greasy, or spicy foods that can worsen diarrhoea
    • Rest the body: Take breaks and get enough sleep to help your system recover more quickly.
    • Monitor symptoms: Keep track of frequency, duration, and severity of diarrhoea, and contact a healthcare provider if it persists or worsens.

    Dizziness Or Drowsiness

    • Sit or Lie Down: If you feel dizzy, sit down or lie down immediately to prevent falling. Keep your head still and close your eyes if needed.
    • Hydrate: Dehydration can cause dizziness, so drink water or electrolyte-replenishing drinks like sports drinks.
    • Avoid Sudden Movements: When standing or sitting, do so slowly to avoid triggering dizziness. Take your time when getting up.
    • Eat Small, Regular Meals: Low blood sugar can cause dizziness, so eat small meals throughout the day and avoid skipping meals.
    • Fresh Air: Sometimes dizziness can be alleviated by taking slow, deep breaths in a well-ventilated area.

    Muscle Cramps

    • Gentle stretching: Slowly stretch the affected muscle and hold the stretch for 20–30 seconds. This helps relax tight muscles.
    • Massage: Gently massage the cramped area to improve blood flow and ease discomfort.
    • Heat therapy: Apply a warm towel or heating pad to relax tight muscles. A warm shower or bath can also help.
    • Cold therapy: If there is soreness after the cramp, apply an ice pack to reduce pain and inflammation.
    • Hydration: Drink enough water and include fluids rich in electrolytes like coconut water to prevent cramps caused by dehydration.
    • Balanced diet: Eat potassium, calcium, and magnesium-rich foods (like bananas, spinach, almonds, and yogurt) to support healthy muscle function.

    Skin rash Or Itching

    • Cool compress: Apply a cold, damp cloth to the itchy area for 5–10 minutes to reduce inflammation and soothe the skin.
    • Oatmeal bath: Add colloidal oatmeal to lukewarm bath water; it helps calm itching and moisturizes dry skin.
    • Moisturize regularly: Use fragrance-free moisturizers, creams, or natural oils like coconut or almond oil to prevent dryness, a common cause of itchiness.
    • Aloe vera gel: Apply pure aloe vera gel to itchy areas to soothe irritation and promote healing.
    • Avoid scratching: Scratching can worsen irritation and cause infection. Tap or gently pat the area instead.
    • Use gentle soaps: Switch to mild, fragrance-free soaps and avoid hot water which can dry out the skin.
    • Stay hydrated: Drink plenty of water to keep your skin hydrated from within.

    Warning & Precautions

    Pregnancy

    Contraindicated

    Use of Telvas Beta 50mg Tablet is not recommended during pregnancy. Studies in humans and animals have shown that telmisartan, a component of this medicine, may cause harm to the foetus. Therefore, this medicine is not recommended for pregnant women. If you are pregnant or suspect you might be, please consult your doctor before using this medication.

    Breastfeeding

    Contraindicated

    Telvas Beta 50mg Tablet is not recommended during breastfeeding. Animal studies indicate that telmisartan can pass into breast milk and could potentially cause harmful effects on the nursing infant. Breastfeeding women should consult their healthcare provider before using this medicine.

    Driving and Using Machines

    Use with Caution

    Use this medicine with caution if you experience dizziness or tiredness after taking it. Avoid driving or operating machinery until you know how the drug affects you. Always consult your doctor for personalized advice.

    Alcohol

    Contraindicated

    Avoid alcohol consumption while taking Telvas Beta 50mg Tablet, as it may worsen low blood pressure or increase side effects. Consult your doctor for guidance.

    Kidney

    Consult your doctor

    Telvas Beta 50mg Tablet is not recommended in patients with impaired kidney function treated with blood pressure medicines containing aliskiren. It should be used cautiously if you have kidney diseases such as renal artery stenosis or have undergone kidney transplant. Consult your doctor before use.

    Liver

    Consult your doctor

    This medicine is not recommended in patients with severe liver disease like cholestasis or biliary obstruction. Caution is advised for patients with hepatic impairment. Always seek your doctor’s advice before starting this medication.

    Allergy

    Contraindicated

    Do not take Telvas Beta 50mg Tablet if you are allergic to telmisartan, metoprolol, or any other ingredients in the formulation.

    Lungs

    Use with Caution

    Take with caution if you have bronchospastic diseases such as asthma, chronic obstructive pulmonary disease, emphysema, or lung infections. Consult your healthcare provider prior to use.

    Heart Disease

    Contraindicated

    This medication is not recommended in patients with severe heart conditions including severe bradycardia, heart block beyond first degree, cardiogenic shock, decompensated heart failure, or sick sinus syndrome. Use with caution if you have other heart problems and consult your doctor before taking this medicine.

    Use In Pediatrics

    Contraindicated

    Telvas Beta 50mg Tablet is not recommended for use in children and adolescents under 18 years, as animal studies have shown potential risks to kidney development and function.

    Use In Geriatrics

    Use with Caution

    Elderly patients (65 years and above) should use this medicine with caution. Regular monitoring of kidney and liver functions is advised. Always consult your healthcare provider before starting or continuing treatment.

    Other Warnings for TELVAS BETA 50MG TABLET

    Before taking Telvas beta 50mg tablet, inform your doctor if you:   

    • Have pheochromocytoma, a tumour of the adrenal glands located above the kidneys
    • Have diabetes or experience low blood sugar levels (hypoglycaemia)
    • Have a history of severe allergic (anaphylactic) reactions, which may include itching, flushed or pale skin, low blood pressure, nausea, or vomiting
    • Have thyrotoxicosis, a condition characterized by excessive thyroid hormone levels in the blood
    • Suffer from peripheral vascular disease, causing reduced blood flow to limbs due to narrowed blood vessels
    • Have elevated aldosterone levels, leading to water and salt retention as well as imbalances in various blood minerals
    • Experience low blood pressure caused by dehydration or significant fluid loss
    • Have salt deficiency caused by diuretic use, low-salt diets, diarrhoea, or vomiting
    • Have high potassium levels in the blood (hyperkalaemia)        

    Who should not take [GBNKEYWORD

    Telvas beta 50mg tablet is not recommended for use if you:

    • Are planned for non-cardiac surgery

    Safety Advice

    • Electrolyte monitoring: Long-term use may affect potassium levels; your doctor may recommend periodic blood tests.
    • Cold or heat sensitivity: Metoprolol may reduce circulation to extremities, causing hands or feet to feel cold.
    • Medication timing: Take consistently at the same time daily for optimal effect; irregular intake may reduce effectiveness.
    • Avoid sudden position changes: Stand up slowly from sitting or lying positions to prevent dizziness or fainting caused by blood pressure drop.
    • Illness or dehydration: Conditions like fever, diarrhoea, or vomiting can affect blood pressure; consult your doctor before adjusting doses.
    • Surgical procedures: Inform your surgeon or anaesthetist if you are taking this medicine before any surgery.
    • Exercise caution: Intense exercise may increase fatigue or dizziness; monitor your body’s response.

    Diet and Lifestyle Advice

    Diet Advice

    • Limit salt intake: Reduce processed and high-sodium foods to help control blood pressure.
    • Eat heart-healthy foods: Include fruits, vegetables, whole grains, and lean proteins in your daily diet.
    • Stay hydrated: Drink enough water throughout the day to support overall circulation.
    • Limit caffeine: It can affect blood pressure control and reduce medicine effectiveness.
    • Include potassium and magnesium-rich foods: Bananas, spinach, nuts, and seeds support heart and muscle function.

    Lifestyle Advice

    • Exercise regularly: Engage in moderate activities like walking, swimming, or yoga for at least 30 minutes most days.
    • Maintain healthy weight: Losing excess weight helps improve blood pressure and heart health.
    • Avoid smoking: Smoking increases heart and blood vessel strain.
    • Manage stress: Practice relaxation techniques like meditation, deep breathing, or mindfulness.
    • Monitor blood pressure: Keep track of your readings to ensure the medicine is effective.

    1. Telvas Beta 50mg Tablet and Atenolol 50mg Tablet for blood pressure control:

    Feature

    Telvas Beta 50mg Tablet

    Atenolol 50mg Tablet

    Composition

    Contains Telmisartan (ARB) + Metoprolol (Beta-blocker)

    Contains Atenolol (Beta-blocker only)

    Action on Blood Pressure

    Works in two ways: relaxes blood vessels (Telmisartan) and slows heart rate (Metoprolol).

    Mainly slows heart rate and reduces heart workload.

    Effectiveness

    More effective for patients whose blood pressure is not controlled with a single medicine.

    Useful in patients who need only heart rate control and blood pressure support.

    Use in Patients

    Suitable for people with high BP and additional heart strain or risk factors.

    Often used in patients with high BP, chest pain (angina), or irregular heartbeat.

    Side Effects

    May cause dizziness, fatigue, slow heartbeat, or stomach upset.

    May cause tiredness, cold hands/feet, or slow heartbeat.

    Doctor’s Advice

    Chosen when dual action is needed for better BP management.

    Chosen when single beta-blocker therapy is enough.

    2. Telvas Beta 50mg Tablet and Telma AM Tablet in a patient:

    Feature

    Telvas Beta 50mg Tablet

    Telma AM Tablet

    Composition

    Contains Telmisartan (ARB) + Metoprolol (Beta-blocker)

    Contains Telmisartan (ARB) + Amlodipine (Calcium channel blocker)

    Action on Blood Pressure

    Relaxes blood vessels (Telmisartan) and slows heart rate (Metoprolol).

    Relaxes blood vessels (Telmisartan) and prevents vessel tightening (Amlodipine).

    Effectiveness

    Suitable when BP control requires heart rate reduction along with vessel relaxation.

    Suitable when BP control requires stronger vessel relaxation and reduced stiffness.

    Use in Patients

    Often prescribed for patients with high BP and added heart strain or irregular heartbeat.

    Often prescribed for patients with high BP and risk of artery stiffness or angina.

    Side Effects

    May cause dizziness, tiredness, slow heartbeat, or stomach upset.

    May cause swelling in ankles/feet, headache, flushing, or dizziness.

    Doctor’s Choice

    Preferred if lowering heart rate is also needed.

    Preferred if reducing artery stiffness and vessel resistance is more important.

    Drug - Drug interaction

    1. Other Blood Pressure Medications:
    Interactions:  
    Combining Telvas Beta with other blood pressure medicines such as ACE inhibitors, ARBs, or diuretics can increase the risk of low blood pressure, dizziness, or kidney issues.
     Management: Your doctor may adjust the doses and monitor your blood pressure and kidney function regularly. Avoid self-adjusting your medications.

    2. Nonsteroidal Anti-Inflammatory Drugs (NSAIDs):
    Interactions:
    Medicines like ibuprofen or naproxen can reduce the effectiveness of Telmisartan and may increase the risk of kidney problems.
    Management: Use NSAIDs only under medical supervision and for short durations. Kidney function may be monitored if long-term use is necessary.

    3. Antiarrhythmic Medicines:
    Interactions:
    Drugs such as amiodarone or digoxin may enhance the heart rate–slowing effect of Metoprolol, increasing the risk of bradycardia or dizziness.
    Management: Your doctor may monitor your heart rate and adjust the dose if needed.

    4. Diabetes Medications:
    Interactions:
    Beta-blockers like Metoprolol may mask early warning signs of low blood sugar, such as a rapid heartbeat.
    Management: Regular blood sugar monitoring is important, and you should not adjust diabetes medications on your own.

    5. Lithium:
    Interactions:
    Telmisartan can increase lithium levels in the blood, raising the risk of lithium toxicity.
    Management: Your doctor may monitor lithium levels and adjust the dose if necessary.

    6. Potassium Supplements or Potassium-Sparing Diuretics:
    Interactions:
    Telmisartan may increase potassium levels in the body, which can be harmful if combined with potassium supplements or certain diuretics.
    Management: Your doctor may check potassium levels regularly and adjust your diet or medications.

    7. CYP2D6-Metabolized Drugs:
    Interactions:
    Some antidepressants or antiarrhythmic drugs are metabolized through CYP2D6, and Metoprolol may increase their levels, leading to more side effects like fatigue, dizziness, or slow heartbeat. 
    Management:
    Dose adjustments and monitoring by your doctor may be required.

    Drug - Food interaction

    1. Foods High in Potassium (e.g., bananas, oranges, spinach, potatoes):
    Interaction:
    Telmisartan may increase potassium levels in the blood. Consuming too many potassium-rich foods while taking this medicine can lead to hyperkalemia (high potassium), which may cause irregular heartbeat or weakness.
    Management: Eat a balanced amount of potassium and follow your doctor’s dietary guidance. Regular blood tests may be recommended to monitor potassium levels.

    2. Grapefruit and Grapefruit Juice:
    Interaction:
    Grapefruit can interfere with the metabolism of some beta-blockers, including Metoprolol, potentially increasing drug levels and side effects such as slow heartbeat, dizziness, or fatigue.
    Management: Avoid grapefruit and grapefruit juice while taking Telvas Beta 50mg Tablet.

    3. High-Sodium Foods (e.g., processed foods, pickles, chips):
    Interaction:
    Excess salt can reduce the effectiveness of blood pressure medicines like Telmisartan. High sodium intake may also worsen hypertension.
    Management: Follow a low-salt diet to improve the effectiveness of Telvas Beta 50mg and support heart health.

    4. Caffeine (coffee, tea, energy drinks):
    Interaction:
    Caffeine may temporarily raise blood pressure, counteracting the effect of the medicine and causing palpitations or jitteriness in some people.
    Management: Limit caffeine intake and monitor your blood pressure to ensure the medicine works effectively.

    Synopsis

    Drug :   Metoprolol, Telmisartan
    Pharmacological Category :   Beta-blockers, Angiotensin II receptor antagonists
    Therapeutic Indication :   Hypertension (high blood pressure)      
    Dosage Forms :   Tablet

    More Information

    Storage

    • Store the tablets in a cool, dry place away from direct sunlight.
    • Keep out of reach of children and pets to avoid accidental intake.

    FAQs About TELVAS BETA 50MG TABLET

    Q: What is Telvas Beta 50mg Tablet used for?

    A: Telvas Beta 50mg Tablet is a prescription medicine that helps support healthy blood pressure levels. It contains a combination of Telmisartan and Metoprolol, which work together to relax blood vessels and control heart rate. Doctors usually recommend it to people who need more than one medicine to keep blood pressure under control. Managing blood pressure is important for reducing strain on the heart. This medicine is taken under medical supervision only.

    Q: How should I take Telvas Beta 50mg Tablet?

    A: Take the tablet exactly as advised by your doctor. It is usually taken once a day with or without food. Try to take it at the same time every day for best results. Swallow it whole with water and do not crush or chew it. Follow your doctor’s instructions carefully for safe use.

    Q: Can Telvas Beta 50mg Tablet be taken on an empty stomach?

    A: Yes, this medicine can be taken with or without food. However, taking it after meals may help reduce stomach discomfort for some people. Always take it with a glass of water. The important thing is to take it regularly at the same time each day as advised by your doctor.

    Q: Are there any common side effects of Telvas Beta 50mg Tablet?

    A: Yes, some people may experience side effects like dizziness, tiredness, slow heartbeat, or stomach discomfort. Headache and lightheadedness may also occur in the beginning. Most of these effects are mild and improve with time. If side effects bother you or do not go away, inform your doctor.

    Q: Can I stop taking Telvas Beta 50mg Tablet suddenly?

    A: No, do not stop taking this medicine suddenly without consulting your doctor. Stopping it on your own may cause a sudden rise in blood pressure or worsen heart conditions. Your doctor may gradually reduce the dose if it needs to be stopped. Always follow medical advice when changing your medicine.

    Q: Does Telvas Beta 50mg Tablet cause dizziness?

    A: Yes, dizziness is a common side effect of this medicine, especially when you first start taking it. It happens because the medicine lowers blood pressure and slows heart rate. To reduce the risk, stand up slowly from sitting or lying positions. If dizziness is severe or persistent, consult your doctor.

    Q: Can Telvas Beta 50mg Tablet affect my heart rate?

    A: Yes, since it contains Metoprolol, it can lower your heart rate. This is usually intended, as it helps reduce strain on the heart. However, if your heartbeat becomes too slow or irregular, you should inform your doctor. Monitoring your pulse regularly may be advised.

    Q: Can Telvas Beta 50mg Tablet be taken with other medicines?

    A: Some medicines may interact with Telvas Beta 50mg Tablet, affecting its safety or effectiveness. Inform your doctor about all medicines you are taking, including herbal supplements. Medicines for heart problems, diabetes, or kidney conditions may require special monitoring. Never start or stop any medicine without medical advice.

    Q: Is Telvas Beta 50mg Tablet habit-forming?

    A: No, this medicine is not habit-forming and does not cause dependence. It is a prescription medicine used to support blood pressure management. However, it should not be taken without medical guidance. Always follow the prescribed dose and duration recommended by your doctor.

    Q: How long does it take for Telvas Beta 50mg Tablet to show results?

    A: You may start noticing improvements in blood pressure within a few hours to days. However, full benefits may take a few weeks of regular use. Since blood pressure medicines work best when taken consistently, continue taking it even if you feel well. Stopping early can reduce its benefits.

    Q: What precautions should I follow while using this medicine?

    A: Take the medicine exactly as prescribed and at the same time each day. Monitor your blood pressure regularly. Avoid alcohol and limit high-salt foods. Inform your doctor about any other medicines you take. Report symptoms like very slow heartbeat, chest pain, or fainting immediately.

    Q: Can Telvas Beta 50mg Tablet be used for anxiety or stress?

    A: Although Metoprolol in this medicine may sometimes reduce symptoms like fast heartbeat, it is not usually prescribed for anxiety or stress. Its main role is in blood pressure and heart-related conditions. Do not use it for anxiety unless specifically advised by your doctor.

    Q: Is it safe for people with diabetes?

    A: People with diabetes can take Telvas Beta 50mg Tablet if prescribed. However, Metoprolol may sometimes mask symptoms of low blood sugar, like rapid heartbeat. This means diabetics should monitor their blood sugar regularly while on this medicine. Inform your doctor if you notice unusual changes.

    Q: Can I take painkillers with Telvas Beta 50mg Tablet?

    A: Some painkillers, especially NSAIDs like ibuprofen, may reduce the effect of this medicine and increase blood pressure. Occasional use may be fine, but long-term use should be avoided without medical advice. Always check with your doctor before combining painkillers with this medicine.

    Q: What should I do in case of an overdose?

    A: Taking more than the prescribed dose may cause very low blood pressure, slow heartbeat, fainting, or breathing problems. If you or someone else has taken too much, seek medical help immediately. Always keep the medicine away from children to avoid accidental overdose.

    References

    1. KD. Tripathi. Antihypertensive Drugs. Essentials of medical pharmacology. Seventh edition. 2013. Page-561, 563.

    2. Jaekyu Shin, Marco Gonzales, and Mark J Pletcher. Risk of Emergent Bradycardia Associated with Initiation of Immediate- or Slow-Release Metoprolol. NIH National Library of Medicine. National Centre for Biotechnology Information. PubMed Central. [Revised in 27th June 2013]. [Accessed on 22nd September 2025] 

    3. AstraZeneca AB. Food and Drug Administration (FDA). [Revised in March 2006] [Accessed on 22nd September 2025] 

    4. Camber Pharmaceuticals, Inc. Metoprolol Succinate Extended-Release Tablets. [Revised in November 2020] [Accessed on 22nd September 2025] 

    Author Details

    Written By Dr. Karthikeyan Rajagopal - M.Pharm (Pharmacology)
    Reviewed For Accuracy By Dr. Thamada Manikanta Praveen - MBBS, MD (General Medicine)
    Last updated on 26 Sep 2025 | 12:12 PM(IST)
    Lab updated