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Emcure Pharmaceuticals Ltd

Sylate Injection 2ml

Bleeding Disorders
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    Introduction About SYLATE INJECTION

    SYLATE INJECTION contains Ethamsylate, which belongs to the group of medicines called Antihemorrhagic drugs. It is used to manage bleeding from the blood vessels and to manage bleeding before or after an operation.

    Ethamsylate exerts hemostatic action by improving platelet adhesiveness and restoring capillary (blood vessels) resistance. It decreases bleeding time and increases platelet clumping which reduces capillary bleeding and improves capillary wall stability. Before the management, your doctor might want to do certain blood tests to understand your existing condition.

    SYLATE INJECTION is not recommended for use if you have porphyria (defect in the synthesis of haemoglobin) or bronchial asthma. Before receiving SYLATE INJECTION inform your doctor if you have hypotension or unstable blood pressure. SYLATE INJECTION should be used with caution in pregnant women. It is not recommended for use in breastfeeding women. Consult your doctor if you experience any unusual effects while receiving SYLATE INJECTION.

    Uses Of SYLATE INJECTION

    • Prevents and manages bleeding from the blood vessels
    • Prevent bleeding before or after an operation

    How SYLATE INJECTION Works

    SYLATE INJECTION exerts hemostatic action by improving platelet adhesiveness and restoring capillary (blood vessels) resistance. It decreases bleeding time and increases platelet clumping which reduces capillary bleeding and improves capillary wall stability. It inhibits PGI-2 synthesis and corrects abnormal platelet function.

    How to use SYLATE INJECTION

    SYLATE INJECTION will be given to you only by a doctor or a nurse into the muscles (intramuscularly) or the veins (intravenously). Your doctor will decide the right dose and duration depending on your age, body weight and disease condition.

    Warning & Precautions

    Pregnancy

    SYLATE INJECTION should be used with caution in pregnant women or if you are planning to have a baby. Consult your doctor before receiving it.

    Breastfeeding

    SYLATE INJECTION is not recommended for use in breastfeeding women as it is unknown if the medicine is excreted in breast milk. Consult your doctor before receiving it.

    Allergy

    Do not receive SYLATE INJECTION if you are allergic to Ethamsylate or any other ingredients of this medicine.

    Lungs

    SYLATE INJECTION is not recommended for use in patients with bronchial asthma. Consult your doctor before receiving SYLATE INJECTION.

    Heart Disease

    SYLATE INJECTION should be used with caution in patients with hypotension and unstable blood pressure. Consult your doctor before receiving SYLATE INJECTION.

    Others

    SYLATE INJECTION is not recommended for use if you:

    • have porphyria (defect in the synthesis of haemoglobin)

    Interactions

    A. Drug-Drug interactions:

    Before receiving SYLATE INJECTION, inform your doctor if you are taking any prescription, nonprescription or herbal medicines.

    Overdosage:

    SYLATE INJECTION will be administered to you only by a doctor or a nurse in a hospital, so it is unlikely to receive an overdose. However, consult your doctor or nurse if you experience any unusual symptoms.

    Synopsis

    Drug :   Ethamsylate
    Pharmacological Category :   Antihemorrhagic agent
    Therapeutic Indication :   Bleeding from blood vessels, perioperative bleeding
    Dosage Forms :   Tablet, Injection

    More Information

    • Keep SYLATE INJECTION out of reach from children
    • Store below 30°C

    FAQs About SYLATE INJECTION

    What is SYLATE INJECTION used for?

    SYLATE INJECTION contains Ethamsylate which belongs to the group of medicines called Antihemorrhagic drugs. It is used to manage bleeding from the blood vessels and to manage bleeding before or after an operation.

    Can SYLATE INJECTION be received by pregnant or breastfeeding women?

    SYLATE INJECTION is not recommended for use in breastfeeding women. And it should be used with caution in pregnant women or women planning to have a baby. Consult your doctor before receiving SYLATE INJECTION.

    How SYLATE INJECTION works?

    It exerts hemostatic action by improving platelet adhesiveness and restoring capillary (blood vessels) resistance. It decreases bleeding time and increases platelet clumping which reduces capillary bleeding and improves capillary wall stability. It inhibits PGI-2 synthesis and corrects abnormal platelet function.

    When is SYLATE INJECTION contraindicated?

    SYLATE INJECTION is not recommended for use in patients with hypersensitivity to this medicine, porphyria (defect in the synthesis of haemoglobin) and bronchial asthma. Consult your doctor for more information.

    Can SYLATE INJECTION be used in patients with heart problems?

    SYLATE INJECTION should be used with caution in patients with hypotension and unstable blood pressure. Consult your doctor for more information on duration and dosage before receiving SYLATE INJECTION.

    References

    1. KD Tripathi. Drugs Affecting Coagulation, Bleeding and Thrombosis. Essentials of medical pharmacology. Eighth Edition. 2019. Page –662.

    2. Ricardo P Garay, Carlo Chiavaroli, Patrick Hannaert. Article name. Therapeutic efficacy and mechanism of action of ethamsylate, a long-standing hemostatic agent. National library of medicine, National center for biotechnology information. Pubmed.gov 2006 [Accessed on 9th July 2022] https://pubmed.ncbi.nlm.nih.gov/16772766/

    3. M.E.IMorgan I.W.TBenson JBenson R.W.I Cooke. Ethamsylate reduces the incidence of periventricular haemorrhage in very low birthweight babies. The lancet 1981. [Accessed on 9th July 2022] https://www.sciencedirect.com/science/article/abs/pii/S014067368191103X

    4. Ethamsylate. CIMS. [Accessed on 9th July 2022] https://www.mims.com/india/drug/info/etamsylate?type=full&mtype=generic

    Useful Diagnostic Tests

    • Blood tests

    Author Details

    Written By Dr. Dhivakaran R - BDS
    Reviewed For Accuracy By Dr. Venkatesh Poludasu - MBBS
    Last updated on 09 Nov 2022 | 04:57 PM(IST)
    Lab updated