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Introduction About STEMETIL MD 5MG TABLET
STEMETIL MD 5MG TABLET contains Prochlorperazine which belongs to the group of medicines called Phenothiazines. It is used for balance problems, dizziness, control nausea and vomiting. It is used for the management of the symptoms of psychotic disorders such as excessive anxiety, tension, confusion, delusions, and agitation.
Avoid exposure to direct sunlight while taking this medicine, as it may make your skin more sensitive to sunlight. Your doctor might prescribe regular tests while you are taking this medicine. These might include blood tests to determine the white blood cell count, blood sugar levels, and an ECG to check if your heart is working properly. Avoid consuming alcohol while taking STEMETIL MD 5MG TABLET, as it may cause serious breathing difficulties. STEMETIL MD 5MG TABLET is not recommended for use if you have brain damage, anemia (blood cell disorder), drowsiness, slower breathing, a weak pulse, a decrease in alertness because of taking certain medications or drinking alcohol, central nervous system depression or bone marrow depression.
STEMETIL MD 5MG TABLET should be used with caution in patients with liver or kidney problems, heart problems, or a family history of heart problems, diabetes, thyroid problems, glaucoma, stroke, and Parkinson’s disease. Consult your doctor before taking. STEMETIL MD 5MG TABLET is not recommended for use in pregnant and breast-feeding women. Consult your doctor before taking STEMETIL MD 5MG TABLET. It is not recommended for use in children under 1 year of age.
STEMETIL MD 5MG TABLET should be used with caution in elderly patients (aged 65 years and older), especially with dementia. The most common side effects of taking STEMETIL MD 5MG TABLET are constipation, dry mouth, drowsiness, and blurred vision. Consult your doctor if any of the side effects worsen.
Uses Of STEMETIL MD 5MG TABLET
It is used:
- for balance problems, dizziness
- to control nausea and vomiting
- for the management of the symptoms of psychotic disorders such as excessive anxiety, tension, confusion, delusions, and agitation
How STEMETIL MD 5MG TABLET Works
STEMETIL MD 5MG TABLET works by balancing the chemicals called dopamine and serotonin (which allow communication between nerve cells) and helps to manage mental illness. It also blocks the action of a chemical called dopamine (which transfers messages to a part of the brain called the vomiting center, which triggers nausea and vomiting) in the brain. Thus, it helps to manage nausea and vomiting effectively.
How to use STEMETIL MD 5MG TABLET
Take STEMETIL MD 5MG TABLET as advised by your doctor. Swallow STEMETIL MD 5MG TABLET with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration of medicine for you depending upon your age, body weight, and disease condition.
Side Effects Of STEMETIL MD 5MG TABLET
Common
- constipation
- dry mouth
- drowsiness, (akathisia) inability to remain still
- blurred vision
Uncommon
- low blood pressure
- peripheral oedema
- irregular heartbeat
- dermatitis
- maculopapular eruptions, erythema multiforme
- urticaria, photosensitivity, abnormal pigmentation
- menstrual irregularities
- gynaecomastia (enlargement of male breast tissue)
- intestinal obstruction
- urinary retention
- headache, insomnia
- increased body temperature
- respiratory depression
Stop taking STEMETIL MD 5MG TABLET and contact your doctor immediately if you experience any of the following side effects:
- rashes, difficulty in swallowing or breathing, swelling of the lips, face, throat or tongue (signs of allergic reaction)
- neuroleptic malignant syndrome which includes symptoms such as an unusually pale complexion, sweating, rise in temperature, rapid heartbeat, stiff muscles, increased breathing rate, confusion, drowsiness or agitation
- agranulocytosis or leukopenia (a blood disorder characterised by frequent infections such as fever, sore throat or mouth ulcers)
- jaundice (yellowing of skin or eyes)
- palpitations (fast, uneven and forceful heartbeats) and breathing problems like wheezing, shortness of breath and chest pain or tightness
- blood clots in the veins of the legs (swelling, pain and redness in the leg), which may travel through blood vessels to the lungs causing chest pain and difficulty in breathing)
- extrapyramidal symptoms such as rigid or stiff muscles, trembling or shaking, body spasm, unusual eye movements such as rolling of the eyes, exaggeration of reflexes, drooling, difficulty moving or loss of muscle power
- sore breast in both men and women
- seizures or fits
- long-lasting and painful erection of the penis
How To Manage Side Effects
Constipation
Try to eat more high-fiber foods such as fresh fruit, vegetables, cereals and drink plenty of water. If this does not help, inform your doctor for receiving alternate management for constipation.
Dizziness Or Drowsiness
Try to rest and relax. Get enough sleep. Avoid driving or operating machinery if you feel drowsiness. Avoid alcohol consumption as it aggravates drowsiness. Consult your doctor if the symptom does not improve.
Dry Mouth
Sip water regularly and other sugar free liquids. Do not use mouthwashes that contain alcohol because they can make your mouth dry, use mouthwash that is used only for dry mouth. Limit your caffeine intake. Avoid smoking or using tobacco products. Consult your doctor if the symptom does not improve.
Headache
Drink ample amount of water and avoid skipping meals. Get adequate rest. Try to be relaxed and stress free. Apply pain relieving balm on your forehead if necessary. Consult your doctor if the symptom does not improve.
Warning & Precautions
Pregnancy
ContraindicatedSTEMETIL MD 5MG TABLET is not recommended for use in pregnant women. Taking this medicine in the last trimester of pregnancy may lead to symptoms like shaking, muscle stiffness, weakness, sleepiness, agitation, breathing problems and difficulty in feeding the new-born baby. Consult your doctor before taking STEMETIL MD 5MG TABLET.
Breastfeeding
ContraindicatedSTEMETIL MD 5MG TABLET is not recommended for use in breastfeeding women. Consult your doctor before taking STEMETIL MD 5MG TABLET.
Driving and Using Machines
Use with CautionDo not drive or operate any machines if you feel sleepy after taking STEMETIL MD 5MG TABLET.
Alcohol
ContraindicatedDo not drink alcohol while you are taking STEMETIL MD 5MG TABLET as it may cause serious breathing difficulties.
Kidney
Use with CautionSTEMETIL MD 5MG TABLET should be used with caution in patients with kidney problems. Consult your doctor before taking STEMETIL MD 5MG TABLET.
Liver
Use with CautionSTEMETIL MD 5MG TABLET should be used with caution in patients with liver problems. Consult your doctor before taking STEMETIL MD 5MG TABLET.
Allergy
ContraindicatedDo not take STEMETIL MD 5MG TABLET if you are allergic to prochlorperazine or any other ingredients of this medicine.
Heart Disease
Use with CautionSTEMETIL MD 5MG TABLET should be used with caution in patients with heart problems or a family history of heart problems. Consult your doctor before taking STEMETIL MD 5MG TABLET.
Use In Pediatrics
ContraindicatedSTEMETIL MD 5MG TABLET is not recommended for use in children under 1 year of age. Contact your child’s doctor for advice.
Use In Geriatrics
Use with CautionSTEMETIL MD 5MG TABLET should be used with caution in elderly patients (aged 65 years and older), especially with dementia. Contact your doctor before taking STEMETIL MD 5MG TABLET.
Others
STEMETIL MD 5MG TABLET is not recommended for use if you have:
- pheochromocytoma (tumour of the adrenal gland)
- brain damage
- anaemia (blood cell disorder), neutropenia (low white blood cell count) and thrombocytopenia (low platelet count)
- drowsiness, slower breathing and weak pulse
- decrease in alertness because of taking certain medications or drinking alcohol
- circulatory collapse
- central nervous system depression (coma or drug intoxication)
Before taking STEMETIL MD 5MG TABLET, inform your doctor if you have:
- thyroid problems
- an enlarged prostate gland
- parkinson’s disease, dementia
- epilepsy or fits (seizures), depression
- myasthenia gravis (weakening of muscle)
- glaucoma (pain in eyes with blurred vision)
- low levels of potassium, calcium and magnesium in the blood
- loss of appetite
- abnormally low weight
- stroke and family history of blood clots
- a scheduled surgery which requires spinal anaesthesia
- to undergo blood test or urine test
- encephalopathy
Interactions
A. Drug-Drug Interactions:
Before taking STEMETIL MD 5MG TABLET, inform your doctor if you are taking any of the following medicines:
- diazepam, clonazepam, and barbiturates like butabarbital and pentobarbital (used to manage insomnia, anxiety, and panic attack)
- amitriptyline, citalopram, escitalopram, and venlafaxine (used to manage depression)
- levodopa (medicines used for Parkinson’s disease)
- carbamazepine (used to manage epilepsy)
- amiodarone, disopyramide, propranolol, or quinidine (used to correct the rhythm of the heartbeat)
- doxazosin, terazosin, guanethidine, guanadrel, bepridil, and clonidine (used to manage high blood pressure)
- glimepiride (used to manage diabetes mellitus)
- vincristine (used to manage cancer)
- clarithromycin, erythromycin, grepafloxacin, sparfloxacin, intravenous erythromycin (used to manage bacterial infections)
- aluminium hydroxide and magnesium hydroxide (used for indigestion and heartburn)
- hyoscyamine (used for irritable bowel syndrome)
- amphetamine (used to manage attention deficit hyperactivity disorder)
- adrenaline
- desferrioxamine (used in patients who have too much iron in the blood)
- lithium (used to manage some types of mental illnesses)
- morphine, codeine, methadone (used to manage severe pain)
- diphenhydramine (used to manage allergies)
- cabergoline (used to manage high levels of prolactin)
- metrizamide (used in radiological examination)
- cisapride (used to manage heartburn)
- sultopride, thioridazine (used to manage schizophrenia)
- intravenous vincamine (used to manage dementia)
- halofantrine (used to manage malaria)
- pentamidine (used to manage pneumonia)
- hydrochlorothiazide (used to manage high blood pressure)
- warfarin (used to manage blood clots)
- chlorzoxazone (medicine used to manage pain and muscle stiffness)
Overdosage:
If you or anyone else accidentally takes too much of STEMETIL MD 5MG TABLET, consult your doctor immediately or visit the nearby hospital. Overdosage symptoms include STEMETIL MD 5MG TABLET include feeling sleepy or dizzy, increased or rapid heartbeat, feeling very cold and confused, writhing movements, feeling restless, stiffness or shaking, and loss of consciousness.
Synopsis
| Drug | : | Prochlorperazine |
| Pharmacological Category | : | Phenothiazines |
| Therapeutic Indication | : | Vertigo, nausea and vomiting, schizophrenia, mania and anxiety |
| Dosage Forms | : | Tablet, Injection |
More Information
- Keep STEMETIL MD 5MG TABLET out of reach of children
- Store STEMETIL MD 5MG TABLET at room temperature
FAQs About STEMETIL MD 5MG TABLET
Q: What is STEMETIL MD Tablet used for?
A: STEMETIL MD Tablet is used in the management of vertigo (balance problems or dizziness arising due from ear-related issues such as Meniere's syndrome and other labyrinthine disorders), nausea and vomiting (due to migraine or other cause). It can serve as a short-term remedy for non-psychotic anxiety, schizophrenia and mania.
Q: How does STEMETIL MD Tablet work?
A: STEMETIL MD 5MG TABLET works by balancing the chemicals called dopamine and serotonin (that allows communication between nerve cells) and helps to manage mental illness. It also blocks the action of a chemical called dopamine (transfers messages to part of the brain called vomiting centre which triggers nausea and vomiting) in the brain. Thus, helps to reduce nausea and vomiting effectively.
Q: Can STEMETIL MD Tablet be used for vertigo?
A: Yes, STEMETIL MD Tablet may be prescribed to alleviate symptoms of vertigo, particularly in cases where nausea and vomiting are present.
Q: Is STEMETIL MD Tablet addictive?
A: STEMETIL MD Tablet is not considered addictive when used as prescribed. However, it should be used cautiously and only as directed by a healthcare professional.
Q: How should STEMETIL MD Tablet be taken?
A: STEMETIL MD Tablet is a mouth dissolving tablet. Place the medicine in the mouth and allow it to dissolve on its own. Do not swallow the medicine.
Q: Can STEMETIL MD Tablet be used during pregnancy?
A: STEMETIL MD 5MG TABLET is not recommended for use in pregnant women. Taking this medicine in the last trimester of pregnancy may lead to symptoms like shaking, muscle stiffness, weakness, sleepiness, agitation, breathing problems and difficulty in feeding the new-born baby. Consult your doctor before taking STEMETIL MD 5MG TABLET.
Q: Does STEMETIL MD Tablet cause drowsiness?
A: Yes, drowsiness is a common side effect of STEMETIL MD Tablet. It may impair your ability to perform tasks that require alertness, such as driving or operating machinery. It's important to avoid such activities until you know how the medication affects you.
Q: Can STEMETIL MD Tablet be used for migraine?
A: Yes, STEMETIL MD Tablet is sometimes prescribed off-label to manage migraines, particularly those accompanied by nausea and vomiting.
Q: What are the common side effects of STEMETIL MD Tablet?
A: Common side effects of STEMETIL MD Tablet may include drowsiness, dizziness, dry mouth, blurred vision, constipation, and weight gain.
Q: Can STEMETIL MD Tablet be used in children?
A: STEMETIL MD Tablet may be used in children under the supervision of a healthcare professional, but the dosage should be carefully adjusted based on the child's age and weight.
Q: How quickly does STEMETIL MD Tablet work for nausea and vomiting?
A: STEMETIL MD Tablet usually starts working within 30 minutes to an hour after administration, but individual responses may vary.
Q: How long can STEMETIL MD Tablet be taken?
A: The duration of STEMETIL MD Tablet management depends on the underlying condition being managed and the individual's response to the medication. It's essential to follow the healthcare professional's instructions regarding duration of use.
Q: Can STEMETIL MD Tablet be used for chemotherapy-induced nausea and vomiting?
A: Yes, STEMETIL MD Tablet is often used to manage nausea and vomiting caused by chemotherapy. However, there are other antiemetic medications available, and the choice depends on various factors, including the type of chemotherapy regimen and the individual's medical history.
Q: Is STEMETIL safe?
A: STEMETIL MD 5mg Tablet is generally safe when used as prescribed by a healthcare professional. However, like all medications, it may cause side effects in some individuals. It's important to follow the recommended dosage and discuss any concerns with your doctor.
Q: Can STEMETIL MD Tablet be used for vertigo?
A: Yes, STEMETIL MD 5mg Tablet may be used to alleviate symptoms of vertigo, particularly those accompanied by nausea and vomiting. It works by blocking dopamine receptors in the brain, which helps to reduce these symptoms.
References
1. K.D Tripathi. Gastrointestinal Drugs. Essentials of Medical Pharmacology. Seventh Edition. 2013. Page 664
2. Linda Skidmore-Roth. Prochlorperazine. Mosby’s 2021 Nursing drug Reference. 34th edition. 2021. Page- 1043
3. Din L, Preuss CV. Prochlorperazine. National Institute of Health. NLM. National Centre for Biotechnology Information. Statpearls. March 2022. [Accessed on 19th March 2024] https://www.ncbi.nlm.nih.gov/books/NBK537083/
4. Famar Health Care Services. Electronic Medicines Compendium (EMC). [Revised in January 2022] [Accessed on 19th March 2024] https://www.medicines.org.uk/emc/files/pil.99.pdf
5. Teva Pharma. (New Zealand) Limited. Medicines and Medical Devices Safety Authority (MEDSAFE). [Revised in August 2017] [Accessed on 19th March 2024] https://www.medsafe.govt.nz/profs/Datasheet/n/Nausafixtab.pdf
6. AA Pharma Inc. Prochlorperazine Tablet. [Revised in August 2012] [Accessed on 19th March 2024] https://www.aapharma.ca/downloads/en/PIL/Prochlorazine_PI.pdf
Useful Diagnostic Tests
- Complete blood count
- Serum Electrolytes
- Blood glucose levels
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