STAPHONEX 500mg Injection 1's
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Introduction About STAPHONEX 500MG INJECTION
STAPHONEX 500MG INJECTION contains Flucloxacillin that belongs to the group of medicines called the Antibiotics. It is used to manage wide range of bacterial infections in the chest (pneumonia, emphysema, lung abscess), tonsils (tonsillitis, quinsy), throat (pharyngitis), sinuses (sinusitis), ears (otitis media, otitis externa), skin & soft tissues (boils, abscesses, carbuncles, impetigo, cellulites, furunculosis, ulcers, acne), wounds, burns, heart (endocarditis), bones & joints (osteomyelitis), membranes of the brain (meningitis), gut (enteritis), blood (septicaemia), kidney, bladder, or the urethra.
STAPHONEX 500MG INJECTION is also used to manage infections occurring after skin grafting or during major surgeries, especially heart or orthopaedic surgery.
A bacterial infection occurs when the bacteria invade the body's defences, increase in number, and cause abnormal reactions in the body such as fever, lymph node swelling, inflammation of the skin, pain (in the heart, muscles, bones, and joints), generalised weakness, cough, soreness, and a burning sensation while urinating. The bacterial infection can become fatal if it spreads widely in the blood.
STAPHONEX 500MG INJECTION is not recommended for use in patients allergic to flucloxacillin, cephalosporins, or other antibiotics. STAPHONEX 500MG INJECTION is also not recommended for use if you have a history of liver diseases such as jaundice after taking flucloxacillin.
STAPHONEX 500MG INJECTION should be used with caution in patients who are being managed for liver problems, kidney problems such as severe kidney failure, or heart problems. STAPHONEX 500MG INJECTION should be used with caution by pregnant and breastfeeding women. STAPHONEX 500MG INJECTION should be used with caution in children and adolescents (below 14 years) and elderly patients (aged 50 years or above). Consult your doctor before taking it.
The common side effects associated with the use of STAPHONEX 500MG INJECTION are minor abdominal disturbances such as stomach upset or diarrhoea. Contact your doctor or a nearby hospital if any of the symptoms worsen.
Uses Of STAPHONEX 500MG INJECTION
It is used to manage wide range of bacterial infections in conditions such as:
- chest (pneumonia, emphysema, lung abscess)
- tonsils (tonsillitis, quinsy)
- throat (pharyngitis)
- sinuses (sinusitis)
- ears (otitis media, otitis externa)
- skin & soft tissues (boils, abscesses, carbuncles, impetigo, cellulites, furunculosis, ulcers, acne)
- wounds
- burns
- heart (endocarditis)
- bones & joints (osteomyelitis)
- membranes of the brain (meningitis)
- gut (enteritis)
- blood (septicaemia)
- kidney
- bladder
- urethra (the tube which carries urine from the bladder)
It is also used to manage infections in conditions such as:
- after skin grafting
- during major surgeries especially heart or orthopaedic surgery
How STAPHONEX 500MG INJECTION Works
STAPHONEX 500MG INJECTION manages the bacterial infection where Flucloxacillin binds to specific sites in the bacterial cell wall and inhibits its process of cell wall synthesis and then kills the bacteria by mediating certain enzymes into it, thereby causing the destruction of the bacterial cell.
How to use STAPHONEX 500MG INJECTION
STAPHONEX 500MG INJECTION will be given to you only by a doctor or a nurse into muscle (intramuscular) or into a vein (intravenous). It can also be given to you by injection into a joint, injection into the lining of the lung, or by breathing in the medicine from a mask (nebuliser). Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.
Side Effects Of STAPHONEX 500MG INJECTION
Common
- minor abdominal disturbances such as stomach upset or diarrhoea
Stop taking STAPHONEX 500MG INJECTION and contact your doctor if you experience any of the following side effects:
- severe diarrhoea with bleeding
- yellowing of eyes and skin
- dark urine faeces
- any unusual bleeding or bruising or skin discolouration
- convulsions (fits) at high doses
- signs of anaemia (low red blood cell count) such as tiredness, breathlessness, light-headedness, a rapid weak pulse, awareness of heartbeat, or headaches
- skin rashes and itching
- blisters in skin, mouth, eyes, or genitals
- sudden wheezing (noisy breathing), difficulty in breathing, or dizziness
- any swelling in face, tongue, or neck
- serious skin reactions
- exanthematous pustulosis (a red scaly rashes and blisters)
How To Manage Side Effects
Diarrhea
Drink lots of fluids, such as water to keep yourself hydrated. Try to avoid taking any medicine on your own to manage diarrhoea and consult your doctor if the symptom gets worse.
Stomach Pain
Try to eat more high-fibre foods such as fresh fruit, vegetables, cereals, and drink plenty of water. Try doing exercise regularly (going for a daily walk or run). If this does not help, inform your doctor for receiving alternate managements for constipation.
Warning & Precautions
Pregnancy
Use with CautionSTAPHONEX 500MG INJECTION should be used with caution if you are pregnant or planning to have a baby. Consult your doctor before taking it.
Breastfeeding
Use with CautionSTAPHONEX 500MG INJECTION should be used with caution in breastfeeding women. Consult your doctor taking it.
Kidney
Use with CautionSTAPHONEX 500MG INJECTION is used with caution in patients being managed for kidney problems such as severe kidney failure. In such cases, the doctor may lower or fewer your dose. Consult your doctor before taking it.
Liver
Consult your doctorSTAPHONEX 500MG INJECTION is not recommended for use in patients with the history of liver diseases such as jaundice (yellowing of skin and the whites of the eyes) after taking flucloxacillin. It should be used with caution in patients who are being managed for liver problems. Consult your doctor before taking it.
Allergy
ContraindicatedSTAPHONEX 500MG INJECTION is not recommended for use in patients allergic to flucloxacillin, cephalosporins, or other antibiotics. Consult your doctor before taking it.
Heart Disease
Use with CautionSTAPHONEX 500MG INJECTION is used with caution in patients being managed for heart problems. Consult your doctor before taking it.
Use In Pediatrics
Use with CautionSTAPHONEX 500MG INJECTION should be used with caution in children and (below 14 years). Consult your doctor before taking it.
Use In Geriatrics
Use with CautionSTAPHONEX 500MG INJECTION should be used with caution in elderly patients (aged 50 years or above). Consult your doctor before taking it.
Others
Before taking STAPHONEX 500MG INJECTION, inform your doctor if you:
- have any serious illness except from the infection for which this management is undertaken
- are taking sodium-restricted diet
- have history of swelling of the face or skin rash while taking an antibiotic
- are getting managed for infections such as syphilis or leptospirosis
- have porphyria (a disorders causing build-up of porphyrin in the body)
- are a carrier of the HLA-B* 5701 allele (gene that increases that makes you susceptible to get allergic reactions with certain drugs such as abacavir)
Interactions
A. Drug-Drug Interactions:
Before taking STAPHONEX 500MG INJECTION, inform your doctor, if you are taking any of the following medicine:
- medicines used to manage gout Ex. probenecid, sulfinpyrazone
- methotrexate (medicine used to manage cancer)
- other types of antibacterial managements such as bacteriostatic agents Ex. chloramphenicol or tetracyclines (Ex. doxycycline)
- paracetamol (medicine used to manage fever)
Overdosage:
STAPHONEX 500MG INJECTION will be given to you only by a doctor or nurse in a hospital, and so it is unlikely to receive an overdose. However, consult your doctor if you experience any unusual symptoms.
Synopsis
| Drug | : | Flucloxacillin |
| Pharmacological Category | : | Antibiotic |
| Therapeutic Indication | : | Bacterial infections |
| Dosage Forms | : | Tablet, Injection |
More Information
- Keep the medicine out of reach of children
- Store STAPHONEX 500MG INJECTION at room temperature
FAQs About STAPHONEX 500MG INJECTION
Q: What is STAPHONEX 500MG INJECTION used for?
A: STAPHONEX 500MG INJECTION is used to manage a wide variety of bacterial infections of the chest (pneumonia, emphysema, lung abscess), tonsils (tonsillitis, quinsy), throat (pharyngitis), sinuses (sinusitis), ears (otitis media, otitis externa), skin & soft tissues (boils, abscesses, carbuncles, impetigo,STAPHONEX 500MG INJECTION is also used to manage infections occurring after skin grafting or during major surgeries, especially heart or orthopaedic surgery.
Q: What happens if you take more STAPHONEX 500MG INJECTION than your required dose?
A: STAPHONEX 500MG INJECTION will be given to you only by a doctor or nurse in a hospital, and so it is unlikely that you will receive an overdose. However, consult your doctor or nurse if you experience any unusual symptoms.
Q: What side effects are seen with STAPHONEX 500MG INJECTION?
A: The common side effects associated with the use of STAPHONEX 500MG INJECTION are minor abdominal disturbances such as stomach upset or diarrhoea. Contact your doctor or a nearby hospital if any of the symptoms worsen.
Q: Who should avoid taking STAPHONEX 500MG INJECTION?
A: STAPHONEX 500MG INJECTION is not recommended for use in patients allergic to flucloxacillin, cephalosporins, or other antibiotics. STAPHONEX 500MG INJECTION is also not recommended for use if you have a history of liver diseases such as jaundice after taking flucloxacillin. Consult your doctor before taking.
Q: How does STAPHONEX 500MG INJECTION work?
A: STAPHONEX 500MG INJECTION manages the bacterial infection where Flucloxacillin binds to specific sites in the bacterial cell wall and inhibits its process of cell wall synthesis and then kills the bacteria by mediating certain enzymes into it, thereby causing the destruction of the bacterial cell.
Q: What is the method of taking STAPHONEX 500MG INJECTION?
A: STAPHONEX 500MG INJECTION will be given to you only by a doctor or a nurse and will be injected into a muscle (intramuscular) or into a vein (intravenous). STAPHONEX 500MG INJECTION can also be given to you by injection into a joint, injection into the lining of the lung, or by breathing in the medicine from a mask (a nebulizer). Your doctor will determine the correct dose and duration for you depending upon your age, body weight, and disease condition.
Q: Is STAPHONEX 500MG INJECTION safe to be used in children and elderly patients?
A: STAPHONEX 500MG INJECTION should be used with caution in children and adolescents (below 14 years of age) and elderly patients (aged 50 years or above) to avoid any potential side effects. Consult your doctor before taking STAPHONEX 500MG INJECTION.
Q: Is STAPHONEX 500MG INJECTION safe to be used in patients with liver disease?
A: STAPHONEX 500MG INJECTION is not recommended for use in patients with a history of liver diseases such as jaundice (yellowing of the skin and the whites of the eyes) after taking flucloxacillin. It should be used with caution in patients who are being managed for liver problems. Consult your doctor before taking STAPHONEX 500MG INJECTION.
Q: Is STAPHONEX 500MG INJECTION safe to be used in kidney patients?
A: STAPHONEX 500MG INJECTION is used with caution in managing patients. In such cases, the doctor may lower or reduce your dose. Consult your doctor before taking STAPHONEX 500MG INJECTION.
Q: Is STAPHONEX 500MG INJECTION safe to be used by pregnant or breastfeeding women?
A: STAPHONEX 500MG INJECTION should be used with caution if you are pregnant or planning to become pregnant, and with caution in women who are breastfeeding their babies. Consult your doctor before taking STAPHONEX 500MG INJECTION.
References
1. Andrew Kingsnorth, Aljafri Majid. Infections in Surgery. Principles of Surgical Practice. 2001. Page – 328.
2. Nick A. Francis, Kerenza Hood, Ronan Lyons, Christopher C. Understanding flucloxacillin prescribing trends and treatment non-response in UK primary care: a Clinical Practice Research Datalink (CPRD) study. NIH National Library of Medicine. National Centre for Biotechnology Information. PubMed Central (PMC). [Assessed on 11th August 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4896409/
3. Istituto Biochimico Italiano S.p.A. Electronic Medicines Compendium (EMC). [Revised in February 2021] [Assessed on 11th August 2022] https://www.medicines.org.uk/emc/files/pil.8745.pdf
Useful Diagnostic Tests
- Kidney Function Test
- Liver Function Test
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