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Introduction About SONADERM M CREAM
SONADERM M CREAM is a combination of Clobetasol and Miconazole which belongs to the group of medicines called Corticosteroids and Antifungals. It is used to manage resistant dermatoses (skin infections) with secondary fungal infections like psoriasis (except widespread plaque psoriasis) and recalcitrant dermatoses.
SONADERM M CREAM is not recommended for use in patients with rosacea, acne vulgaris, perioral dermatitis, pruritus without inflammation, perianal and genital pruritus. SONADERM M CREAM should be used with caution in patients with liver or kidney disease and psoriasis. Contact your doctor before applying.
Use of SONADERM M CREAM during pregnancy should only be considered if the expected benefit to the mother outweighs the risk to the foetus. Contact your doctor before applying. Use of SONADERM M CREAM during lactation should only be considered if the expected benefit to the mother outweighs the risk to the infant. Contact your doctor before applying.
SONADERM M CREAM is not recommended for use in children under 1 year of age and should be used with caution in children above 1 year of age. Contact your doctor before applying. SONADERM M CREAM should be used with caution in elderly patients. Contact your doctor before applying. The most common side effects of this medicine are pruritus, skin burning or skin pain. Contact your physician if any of the symptoms worsen.
Uses Of SONADERM M CREAM
It is used to manage:
- resistant dermatoses (skin infections) with secondary fungal infection Ex. psoriasis (except widespread plaque psoriasis)
- recalcitrant dermatoses
How SONADERM M CREAM Works
SONADERM M CREAM helps to manage infection, where Clobetasol belongs to Corticosteroids which blocks the production of certain chemical messengers (prostaglandins) that make the skin red, swollen, and itchy and Miconazole is an antifungal which inhibits the fungal growth.
How to use SONADERM M CREAM
Apply SONADERM M CREAM as directed by your physician. It is for external use only. Apply a thin layer of the medicine to the affected area of the skin and rub it gently. Avoid contact with eyes.
Side Effects Of SONADERM M CREAM
Common
- pruritus, skin burning or skin pain
Uncommon
- skin atrophy
- stretch marks
- inflammation of skin
- hypopigmentation
- application site irritation
Rare
Stop using SONADERM M CREAM and contact your physician immediately if you experience any of the following side effects:
- severe allergic reactions such as anaphylaxis or angioedema (skin rash, swelling of face, lips, tongue, or throat causing breathing difficulty)
Warning & Precautions

Pregnancy
Consult your doctorUse of SONADERM M CREAM during pregnancy should only be considered if the expected benefit to the mother outweighs the risk to the foetus. Contact your doctor before applying.

Breastfeeding
Consult your doctorUse of SONADERM M CREAM during lactation should only be considered if the expected benefit to the mother outweighs the risk to the infant. Contact your doctor before applying.

Kidney
Use with CautionSONADERM M CREAM should be used with caution in patients with kidney disease. Contact your doctor before applying.

Liver
Use with CautionSONADERM M CREAM should be used with caution in patients with liver disease. Contact your doctor before applying.

Allergy
ContraindicatedDo not use SONADERM M CREAM if you are allergic to Clobetasol, Miconazole or to any other ingredients of this medicine.

Use In Pediatrics
Consult your doctorSONADERM M CREAM is not recommended for use in children under 1 year of age and should be used with caution in children above 1 year of age. Contact your doctor before applying.

Use In Geriatrics
Use with CautionSONADERM M CREAM should be used with caution in elderly patients. Contact your doctor before applying.
Others
SONADERM M CREAM is not recommended for use if you have:
- rosacea
- acne vulgaris
- perioral dermatitis
- pruritus without inflammation
- perianal and genital pruritus
Before applying SONADERM M CREAM inform your doctor if you have:
- infections
- psoriasis
- chronic leg ulcers
Interactions
A. Drug-Drug interactions:
Before using SONADERM M CREAM inform your doctor if you are taking the following medicine:
- ritonavir (medicines used for HIV infections)
- itraconazole (medicines used for fungal infections)
- warfarin (medicines used to manage or manage blood clots)
Overdosage:
If you or anyone else accidentally uses too much of SONADERM M CREAM, consult your doctor immediately or visit the nearby hospital.
Synopsis
Drug | : | Clobetasol, Miconazole |
Pharmacological Category | : | Corticosteroids, Antifungals |
Therapeutic Indication | : | Skin infections |
Dosage Forms | : | Cream |
More Information
- Keep out of reach of children
- Store SONADERM M CREAM below 25°C
FAQs About SONADERM M CREAM
Q: What are the possible side effects of applying SONADERM M CREAM?
A: The most common side effects of this medicine are pruritis, skin burning sensation or skin pain. Contact your physician if any of the symptoms worsen.
Q: Can I stop applying SONADERM M CREAM?
A: Do not stop applying SONADERM M CREAM suddenly without consulting your doctor, as it leads to adrenal insufficiency. Therefore, it is important to apply SONADERM M CREAM until your doctor advice you to stop.
Q: Can I use SONADERM M CREAM for long time?
A: No. Do not apply SONADERM M CREAM for more than four weeks without medical supervision. If the condition worsens or does not improve within four weeks, Contact your doctor.
Q: Can I use SONADERM M CREAM in psoriasis?
A: SONADERM M CREAM should be used with caution in patients with psoriasis due to risk of rebound relapses, generalised pustular psoriasis, development of tolerance, local or systemic toxicity due to impaired skin barrier. Contact your doctor before applying.
Q: Can I use SONADERM M CREAM in children?
A: Yes. SONADERM M CREAM should be used with caution in children above 1 year of age. Contact your doctor before applying.
References
1. K.D. Tripathi. Drugs acting on the skin and mucous membrane & Antifungal drugs. Essentials of medical pharmacology. Seventh edition. 2013. Page – 895, 792.
2. Bethesda (MD). Clobetasol. National Institute of Health. NLM. National Centre for Biotechnology Information. PubChem Compound Summary. 2004. [Accessed on 17th June 2022] https://pubchem.ncbi.nlm.nih.gov/compound/5311051
3. Bethesda (MD). Miconazole. National Institute of Health. NLM. National Centre for Biotechnology Information. PubChem Compound Summary. 2004. [Accessed on 17th June 2022] https://pubchem.ncbi.nlm.nih.gov/compound/4189
4. GlaxoSmithKline Pharmaceuticals Limited. Clobetasol propionate and miconazole nitrate. [Revised on May 2021] [Accessed on 24th June 2022] https://india-pharma.gsk.com/media/6416/tenovate-m.pdf