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Introduction About S AMLEOD 5 TABLET
S AMLEOD 5 TABLET contains S-Amlodipine which belongs to the group of medicines called Antihypertensives. It is used to manage essential hypertension (abnormal high blood pressure which occurs mostly due to obesity, family history or unhealthy diet) and angina pectoris (type of chest pain due to reduced blood flow to the heart).
S AMLEOD 5 TABLET is not recommended for use in patients with certain heart problems. S AMLEOD 5 TABLET should be used with caution in patients having liver and kidney impairment. S AMLEOD 5 TABLET should be used with caution in pregnant and breastfeeding women only if clearly advised by the doctor.
S AMLEOD 5 TABLET should be used with caution in elderly patients so, consult your doctor before taking it. The most common side effects of taking S AMLEOD 5 TABLET are headache, nausea, abdominal pain, diarrhoea, indigestion and visual disturbances, etc. Consult your doctor if any of the side effects worsen.
Uses Of S AMLEOD 5 TABLET
Manages,
- essential hypertension
- angina pectoris
How S AMLEOD 5 TABLET Works
S AMLEOD 5 TABLET reduces blood pressure by a direct relaxant effect on smooth muscle of blood vessels. In angina, it works by reducing the pressure against which the heart works, stabilizing the heart rate and thus reducing energy consumption and oxygen requirements by the heart muscle. It also probably dilatates the main coronary arteries and increases oxygen delivery by heart muscle in patients with coronary artery spasm.
How to use S AMLEOD 5 TABLET
Take S AMLEOD 5 TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Correct dosage and duration of S AMLEOD 5 TABLET will be prescribed to you by your doctor depending upon your age, body weight and disease condition.
Side Effects Of S AMLEOD 5 TABLET
Common
- somnolence (over sleepiness), dizziness, headache
- visual disturbance including double vision
- palpitation (irregular and fast heartbeat)
- flushing
- dyspnoea (breathing difficulties)
- stomach pain, nausea, indigestion, altered bowel habits (diarrhoea and constipation)
- ankle swelling, muscle cramps
- edema (fluid retention)
- fatigue (weakness), asthenia (reduced muscle strength)
Uncommon
- depression, mood changes (including anxiety), lack of sleep
- tremor (shaking movements of hands), altered taste sensation
- syncope (fainting), numbness
- tingling or prickling sensation in hands, legs or feet
- tinnitus (ringing in ears)
- irregular heartbeat including slow and fast heartbeat
- low blood pressure
- cough, rhinitis (runny nose)
- vomiting, dry mouth
- hair loss, purpura (purple spots in skin), skin discolouration
- excessive sweating, pruritus (itchiness), rash (with or without disease or fever), hives
- joint, muscle or back pain
- urination disorder, frequent urination at night, increased urinary frequency
- impotence, gynaecomastia (breast enlargement in males)
- chest pain, pain, malaise (general unwell feeling)
- increased or decreased weight
Rare
- confusion
How To Manage Side Effects

Constipation
Eat plenty of fibre rich foods such as fresh fruits, vegetables, and cereals and drink plenty of water. Exercise more regularly. Consult your doctor if the symptom does not improve .

Diarrhea
Drink lot of fluids such as water to keep yourself hydrated. Avoid eating high-fat or spicy foods. Do not take any medicine on your own to manage diarrhea without consulting your doctor.

Headache
Apply hot or cold-water bag on your head. Try to take rest in a quiet and dark room. Drink tea or coffee. Massage the scalp or head with mild pressure. Consult your doctor if the symptom gets worse.

Indigestion
Raise your head and shoulders up while sleeping as this can manage stomach acid from coming up. Do not eat 3 to 4 hours before going to bed and avoid tea, coffee, cola, or alcohol. If indigestion does not improve, consult your doctor.

Nausea And Vomiting
Take S AMLEOD 5 TABLET with or just after meals. Stick to simple meals. Avoid eating oily, fried or spicy foods. Do not lie down or sleep immediately after eating. Consult your doctor if the symptom does not improve

Stomach Pain
Try to rest and relax. Eat and drink slowly or try to eat smaller meals more frequently. Keep a heat pad on your stomach. If you stomach still aches, consult your doctor.
Warning & Precautions

Pregnancy
Monitoring requiredS AMLEOD 5 TABLET should be used with caution in pregnant women only if considered clearly necessary. Consult your doctor before taking S AMLEOD 5 TABLET.

Breastfeeding
Monitoring requiredS AMLEOD 5 TABLET should be used with caution in breastfeeding women only if considered clearly necessary. Consult your doctor taking S AMLEOD 5 TABLET

Driving and Using Machines
Use with CautionDo not drive or operate any machines if you experience dizziness, headache, fatigue (extreme tiredness), impaired ability to react or nausea after taking S AMLEOD 5 TABLET.

Kidney
Use with CautionS AMLEOD 5 TABLET should be used with caution in patients having kidney impairment. Consult your doctor before taking S AMLEOD 5 TABLET.

Liver
Use with CautionS AMLEOD 5 TABLET should be used with caution in patients having liver impairment. Consult your doctor before taking S AMLEOD 5 TABLET.

Allergy
ContraindicatedS AMLEOD 5 TABLET is not recommended for use if you are allergic to dihydropyridine derivatives (such as felodipine, nimodipine), S-Amlodipine, or any of the other ingredients of this medicine.

Heart Disease
Consult your doctorS AMLEOD 5 TABLET is not recommended for use in patients with severe hypotension (low blood pressure), shock including cardiogenic shock (serious condition caused by the sudden drop in blood flow through the body, high grade aortic stenosis (obstruction of the outflow tract of the left ventricle), or haemodynamically unstable heart failure after heart attack. S AMLEOD 5 TABLET should be used with caution in patients with congestive heart failure. Consult your doctor before taking S AMLEOD 5 TABLET

Use In Pediatrics
Consult your doctorSafety and effectiveness of S AMLEOD 5 TABLET is not established in children. Consult child’s doctor for advice.

Use In Geriatrics
Use with CautionS AMLEOD 5 TABLET should be used with caution in elderly patients. Consult your doctor before taking it.
Interactions
A. Drug - Drug interactions:
Before taking S AMLEOD 5 TABLET, inform your doctor if you are taking any of the following medicines:
- medicines used to manage certain viral infections (Ex. indinavir, ritonavir)
- medicines used to manage fungal infections (Ex. ketoconazole, miconazole)
- certain medicines used to manage bacterial infections (Ex. erythromycin, clarithromycin, rifampicin)
- certain medicines used to lower blood pressure (Ex. verapamil, diltiazem)
- dantrolene infusion (used to manage muscle stiffness)
- medicines used to manage graft rejection (Ex. tacrolimus, cyclosporine)
- simvastatin (used to reduce blood cholesterol)
- st. john's wort (used to manage depression)
B. Drug - Food interaction:
Avoid eating grapefruit or drinking grapefruit juice while taking S AMLEOD 5 TABLET as it may drop your blood pressure further.
Overdosage:
If you or anyone else accidentally take too much of S AMLEOD 5 TABLET, consult your doctor immediately or visit the nearby hospital. The common symptoms of overdose are low blood pressure and fast heartbeat.
Synopsis
Drug | : | S-Amlodipine |
Pharmacological Category | : | Calcium Channel Blockers |
Therapeutic Indication | : | Essential hypertension, Angina pectoris |
Dosage Forms | : | Tablet |
More Information
- Keep S AMLEOD 5 TABLET out of reach of children
- Store at room temperature
FAQs About S AMLEOD 5 TABLET
Q: What is S AMLEOD 5 TABLET and why is it given?
A: S AMLEOD 5 TABLET contains S-Amlodipine which is used in the management of essential hypertension (high blood pressure that is not caused by any other condition is called essential hypertension) and angina pectoris (chest pain).
Q: Is S AMLEOD 5 TABLET safe in pregnant women?
A: S AMLEOD 5 TABLET is only recommended for use in pregnant women when there is no safer alternative and when the disease itself carries greater risk for the mother and the baby. If you are pregnant, think you may be pregnant or planning to get pregnant, consult your doctor before taking this medicine. Inform your doctor immediately if you become pregnant during management with S AMLEOD 5 TABLET.
Q: Can S AMLEOD 5 TABLET be taken by patients with heart disease?
A: S AMLEOD 5 TABLET is not recommended for use in patients with severe hypotension (low blood pressure), shock including cardiogenic shock (life threatening condition caused by the sudden drop in blood flow through the body), blood flow obstruction to left ventricle (Ex. high grade aortic stenosis), haemodynamically unstable heart failure after heart attack and it should be used with caution in patients with congestive heart failure. Consult your doctor for advice before taking S AMLEOD 5 TABLET
Q: Does S AMLEOD 5 TABLET cause skin rash?
A: Yes, S AMLEOD 5 TABLET may cause skin rash in some people. Try to avoid hot showers because it may cause skin irritation. Avoid frequent contact and rubbing over the affected area. Use sunscreen and protective clothing when going outdoors. If this symptom does not get better, consult your doctor for advice
Q: What are the common side effects of S AMLEOD 5 TABLET?
A: The common side effects of taking S AMLEOD 5 TABLET are somnolence (over sleepiness), dizziness, headache, visual disturbance including double vision, palpitation, flushing, shortness of breath, stomach pain, nausea, indigestion, altered bowel habits (diarrhoea and constipation), muscle cramps, weakness, reduced muscle strength, fluid retention and ankle swelling
Q: Can I take other medicines with S AMLEOD 5 TABLET?
A: Before taking S AMLEOD 5 TABLET, inform your doctor if you are taking, have taken, or might take any other medicine, including prescription, over the counter or any herbal medicine, as these might cause serious unusual effect by interacting with each other.
References
1. KD. Tripathi. Antianginal and Other Anti-Ischaemic Drugs. Essentials of medical pharmacology. Eighth edition. 2019. Page –595.
2. Thacker, Hemant P. S-amlodipine--the 2007 clinical review. Europe PMC. April 2007. [Accessed on 29th July 2022] https://europepmc.org/article/med/17822186
3. Selcuk Sen, Meral Demir, Zerrin Yigit, and Ali Yagiz Uresin. Efficacy and Safety of S-Amlodipine 2.5 and 5 mg/d in Hypertensive Patients Who Were Treatment-Naive or Previously Received Antihypertensive Monotherapy. NIH National Library of Medicine, National center for biotechnology information. PubMed Central. July 2018. [Accessed on 29th July 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974697/
4. Torrent Pharmaceuticals Ltd. Esam (S-Amlodipine Besylate Tablets). [Revised in January 2017]. [Accessed on 29th June 2022] https://www.torrentian.com/pisheet/Upload/PI_Sheet/1626.pdf
5. Zuventus healthcare. Eslo Tablet (S (-) Amlodipine). [Accessed on 29th July 2022] http://www.zuventus.co.in/patient_wise_products_selected.aspx?Medi_Id=25
Useful Diagnostic Tests
- Complete Blood Count (CBC)
- Electrocardiogram (ECG)