RENOLOG Tablet 15's

Introduction About RENOLOG TABLET

Renolog Tablet is a nutritional supplement enriched with Alpha Ketoanalogue. It is used as a part of dietary support for individuals aiming to maintain kidney health, particularly in cases of chronic kidney conditions. When taken in combination with a low-protein diet, it provides targeted nutritional assistance to help support kidney function and aids in the management of metabolic waste build-up, including urea, in the body. This formulation is often included in nutritional plans recommended by healthcare professionals for improved metabolic balance.

Renolog Tablet should be taken orally, with or without food, exactly as directed by your doctor. For best results, it is often recommended to be used alongside a low-protein diet, ensuring you meet your daily calorie requirements during the course. Your doctor may advise periodic monitoring of serum calcium levels to ensure safe and effective use. Always follow the prescribed dose and duration without altering your regimen on your own.

The most common side effects of this medicine include increased calcium levels (hypercalcemia), nausea, vomiting, diarrhea, and abdominal pain. Before using Renolog Tablet, inform your doctor about any other medicines you are taking for existing health conditions. Do not use this supplement if you are allergic to any of its components or if you have elevated calcium levels (hypercalcemia). Your doctor may recommend regular calcium level checks during the course of use to ensure safe consumption.

Avoid taking Renolog Tablet together with calcium-based supplements or certain antibiotics such as tetracyclines or quinolones, unless advised by your doctor, as these may affect absorption. If you are pregnant or breastfeeding, or have liver-related health issues, consult your doctor before use. Refrain from driving or operating machinery until you know how this supplement affects your alertness.

Uses Of RENOLOG TABLET

• Chronic kidney disease

Benefits of RENOLOG TABLET

1)Supports Kidney Function and Reduces Urea Levels: Renolog Tablet provides essential amino acids as alpha ketoanalogues which support kidney function by minimizing the accumulation of nitrogenous waste products like urea. This helps ease the workload on the kidneys and supports metabolic balance in individuals with chronic kidney conditions.

2)Nutritional Support Alongside Low-Protein Diets: Designed for use with a low-protein diet, Renolog supports nutritional status by supplying critical amino acid building blocks. This supplementation helps preserve muscle mass and metabolic health during kidney disease management.

3)May Delay Progression of Chronic Kidney Disease: By improving protein metabolism and reducing the strain on renal function, Renolog Tablet potentially assists in slowing the advancement of chronic kidney disease, thereby supporting better long-term kidney health.

4)Promotes Metabolic Balance and Reduces Toxic Waste: Renolog facilitates nitrogen recycling by converting ketoanalogues into essential amino acids. This process reduces toxic nitrogenous waste, contributing to improved metabolic function and patient well-being.

5)Supports Safe and Monitored Kidney Care: When used as part of a medically supervised plan that includes regular serum calcium monitoring, Renolog Tablet offers a safe nutritional approach to kidney health, complementing other dietary and medical interventions.

How RENOLOG TABLET Works

Renolog Tablet is formulated with essential amino acids in the form of Alpha Ketoanalogue. This nutritional supplement helps lower blood levels of urea and other nitrogenous waste products by promoting nitrogen recycling. It is ideal for individuals following a low or very low protein diet, supporting metabolic balance, and helping maintain kidney wellness.

How Renolog Tablet Works in the Body:

After ingestion, the alpha ketoanalogues in Renolog are converted into essential amino acids by utilizing nitrogen from non-essential amino acids. This process reduces the nitrogen load on the kidneys, thereby helping to preserve remaining kidney function without increasing metabolic waste.

Renolog Tablet: Mechanism of Action Explained:

Renolog functions by following metabolic pathways similar to amino acids, supporting protein metabolism while minimizing the accumulation of toxic metabolites like urea. This mechanism helps reduce kidney strain in chronic kidney conditions.

Alpha Ketoanalogue – The Science Behind Renolog:

Alpha ketoanalogues are precursors to essential amino acids that do not contribute to nitrogenous waste. Their supplementation with Renolog helps maintain amino acid balance and metabolic health in patients with impaired kidney function.

Benefits of Nitrogen Recycling with Renolog Tablet:

Renolog facilitates nitrogen recycling by converting ketoanalogues into amino acids, reducing the accumulation of nitrogenous waste. This supports metabolic stability and helps delay progression of kidney impairment.

Role of Renolog in Protein Metabolism and Kidney Support:

By improving protein metabolism through Ketoanalogue supplementation, Renolog supports nutritional status and reduces metabolic complications associated with kidney dysfunction.

Why Urea Reduction Matters in Renolog Supplementation:

Elevated urea is a common metabolic waste in kidney disease. Renolog helps decrease blood urea levels, thereby alleviating the toxic burden on kidneys and helping maintain overall renal health.

Understanding Catabolic Pathway Modulation by Renolog Tablet:

Renolog modulates catabolic pathways by supplying essential protein building blocks without increasing nitrogen intake, enabling safer metabolic processing, and supporting the kidneys in chronic disease management.

How to use RENOLOG TABLET

• Take Renolog Tablet orally with or without food, exactly as prescribed by your doctor.
• Swallow the tablet whole with a glass of water; do not chew, crush, or break it.
• For optimal results, use Renolog alongside a low-protein diet while maintaining adequate daily calorie intake.
• Follow the prescribed dose and schedule consistently.

How to Take Renolog Tablet for Best Results:

• Take Renolog Tablet at the same time each day, preferably during meals to enhance absorption.
• Adhering to your doctor’s dosage instructions and combining the tablet with a renal-friendly diet can help maximize its benefits for kidney health.

Renolog Tablet Dosage Guidelines:

• Dosage is typically individualized based on body weight and kidney function.
• Your healthcare provider will determine the correct dose and duration.
• Do not alter the dose or stop management without consulting your doctor.

Administration: When and How to Consume Renolog Tablet:

• Take the tablet three times daily or as directed, ideally with meals.
• Always swallow the tablet whole.
• Maintaining consistent administration timing supports steady metabolic effects and kidney function support.

Important Dosage and Safety Instructions:

• Never exceed the prescribed dose.
• Ensure regular medical check-ups, especially for monitoring serum calcium levels during use.
• Inform your doctor if you experience any unusual symptoms or side effects.

What if I forgot to take RENOLOG TABLET

• If you miss a dose, take it as soon as you remember.
• If it is almost time for the next dose, skip the missed one.
• Do not double the dose to compensate for missed medication.

Side Effects Of RENOLOG TABLET

Like all medicines, Renolog Tablet may cause certain side effects in some individuals, although not everybody gets them.

The most common side effects of taking Renolog Tablet are:

• Increased calcium levels (hypercalcemia)
• Nausea
• Vomiting
• Diarrhea
• Abdominal pain

When to consult your doctor?

• Severe allergic reactions such as skin rash, itching, swelling of the face, tongue, or throat
• Difficulty breathing or shortness of breath
• Severe dizziness, fainting, or loss of consciousness

How To Manage Side Effects

Headache

• Rest in a Quiet, Dark Room: Find a calm environment away from bright lights and loud noises. Lie down, close your eyes, and relax to help ease discomfort.
• Stay Hydrated: Drink plenty of water or clear fluids throughout the day, as dehydration can trigger or worsen headaches.
• Apply a Cold or Warm Compress: Place a cold pack on your forehead to numb the pain or use a warm compress on your neck and shoulders to relieve muscle tension.
• Take Pain Relief if Appropriate: If advised by your doctor, you may use mild over-the-counter pain relievers such as acetaminophen or ibuprofen. Always follow the recommended dosage.
• Practice Relaxation Techniques: Gentle stretching, yoga, meditation, or deep breathing exercises can help reduce stress and alleviate headache intensity.
• Monitor Symptoms: If headaches become severe, persistent, or are accompanied by other symptoms such as vision changes or dizziness, seek medical advice immediately.
• Follow Your Doctor’s Recommendations: Keep track of headache episodes and discuss them during your follow-up visits so your management can be adjusted if needed.

Nausea And Vomiting

• Rest in a Comfortable Position: Sit or lie down in a quiet, well-ventilated space to help ease nausea sensations. Avoid sudden movements.
• Stay Hydrated: Drink small sips of water, oral rehydration solutions, or clear fluids frequently to reduce dehydration caused by vomiting.
• Eat Light and Bland Foods: Consume easily digestible foods such as crackers, toast, bananas, rice, or applesauce to reduce stomach irritation.
• Avoid Strong Odors and Spicy Foods: These may trigger or worsen nausea and vomiting symptoms.
• Take Medication with Food: Taking Renolog Tablet with meals may help reduce the chances of nausea.
• Use Anti-Nausea Remedies if Recommended: Consult your doctor about safe over-the-counter remedies or prescription antiemetics if nausea is persistent.
• Monitor Symptoms: If nausea or vomiting worsens, becomes severe, or leads to dehydration, contact your healthcare provider promptly for evaluation.
• Follow Doctor’s Instructions: Always take Renolog Tablet exactly as prescribed and report any side effects during your medical check-ups.

Stomach Pain

• Rest and Avoid Straining: If you experience abdominal discomfort, try resting and avoid activities that increase stomach strain or pressure.
• Monitor Your Symptoms: Mild abdominal pain is common and often resolves on its own. Keep track of the intensity and duration of your pain.
• Eat Small, Bland Meals: Consuming light, easy-to-digest foods like rice, toast, or bananas may help reduce stomach irritation.
• Stay Hydrated: Drinking plenty of fluids can help maintain digestion and reduce discomfort.
• Avoid Alcohol and Spicy Foods: These can worsen abdominal pain or cause irritation.
• Inform Your Doctor: If abdominal pain worsens, persists, or is accompanied by other symptoms like vomiting, severe cramps, or fever, seek medical advice promptly.
• Follow Prescribed Dosage: Ensure you take Renolog Tablet as directed to minimize side effects, and do not self-adjust the dosage.

Warning & Precautions

Pregnancy

Consult your doctor

Use Renolog Tablet during pregnancy only if clearly needed and prescribed by your doctor. The safety and effectiveness in pregnant women have not been established. Always consult your healthcare provider before use to weigh potential benefits and risks.

Breastfeeding

Use with Caution

Caution is advised when taking Renolog Tablet while breastfeeding. There is limited information about its safety in nursing mothers. Consult your doctor before use to ensure it is appropriate for you and your baby.

Driving and Using Machines

Use with Caution

Renolog Tablet may cause drowsiness or affect mental alertness in some individuals. Avoid driving or operating machinery until you know how this medication affects you to reduce accidents.

Alcohol

Consult your doctor

Alcohol consumption should be avoided during Renolog Tablet management as it may increase the risk of side effects or interfere with the medication’s effectiveness. Discuss with your doctor if you consume alcohol.

Kidney

Consult your doctor

Renolog Tablet is generally considered safe for patients with kidney disease when prescribed by a doctor. No dose adjustment is typically required, but regular monitoring and follow-up are important to ensure safe use.

Liver

Use with Caution

Use Renolog Tablet cautiously if you have liver impairment. There is limited data on its safety in liver disease, and your doctor will decide if the benefits outweigh the risks. Inform your healthcare provider about any liver conditions before starting management.

Allergy

Contraindicated

Do not take Renolog Tablet if you are allergic to alpha ketoanalogues or any of its ingredients. Inform your doctor immediately if you notice any allergic reactions such as rash, itching, swelling, or difficulty breathing.

Use In Pediatrics

Consult your doctor

The safety and efficacy of Renolog Tablet in children have not been established. It is generally not recommended for pediatric use unless specifically prescribed by a healthcare professional.

Use In Geriatrics

Use with Caution

Elderly patients may use Renolog Tablet with caution and under medical supervision. Regular monitoring is advised to manage any age-related changes in kidney or liver function and to avoid potential side effects.

Other Warnings for RENOLOG TABLET

Before taking the RENOLOG Tablet, inform your doctor if you have:

• Hereditary phenylketonuria

Who should not take [GBNKEYWORD

RENOLOG Tablet is not recommended for use if you have:

• Hypercalcemia (high levels of calcium in the blood)
• Disturbed amino acid metabolism

Diet and Lifestyle Advice

Drug - Drug interaction

Inform your physician if you are taking any of the following medicine before taking Renolog Tablet:

1. Calcium-Containing Supplements (e.g., Calcium carbonate, Calcium citrate)
   • Interaction: May reduce the absorption of Renolog Tablet, decreasing its effectiveness.
   • Effects: Lower bioavailability of alpha ketoanalogue, potentially reducing therapeutic benefits.
   • Management: Avoid concurrent use without medical advice. If co-administered, doctors may recommend spacing the doses apart and close monitoring of management effectiveness.
2. Certain Antibiotics (e.g., Tetracyclines, Quinolones such as Ciprofloxacin)
   • Interaction: These antibiotics can interfere with the absorption of Renolog Tablet.
   • Effects: Reduced efficacy of Renolog and possible suboptimal kidney support.
   • Management: Inform your doctor if taking these antibiotics. They may adjust dosing schedules or monitor clinical response carefully.
3. Safinamide and Tranylcypromine (Monoamine Oxidase Inhibitors)
   • Interaction: Concurrent use may increase risk of serotonin syndrome, a rare but serious condition.
   • Effects: Symptoms may include mental status changes, autonomic dysfunction, and neuromuscular abnormalities.
   • Management: Avoid combination unless closely supervised by a healthcare professional. Immediate medical attention is necessary if symptoms occur.
4. Drugs that Affect Serum Calcium Levels
   • Interaction: Renolog can increase serum calcium; combining with other drugs affecting calcium may cause hypercalcemia.
   • Effects: Risk of elevated calcium leading to nausea, vomiting, muscle weakness, or cardiac arrhythmias.
   • Management: Regular monitoring of serum calcium is recommended. Adjust medications under doctor’s supervision to maintain safe calcium levels.

Drug - Food interaction

1. Protein Intake Considerations
   • Interaction: High-protein foods like meat, cheese, and eggs should be limited while taking Renolog Tablet.
   • Effects: Excess protein intake can increase nitrogenous waste, counteracting the supplement's purpose which is to support kidney function alongside a low-protein diet.
   • Management: Adhere to a low-protein diet as recommended by your healthcare provider to maximize the benefits of Renolog Tablet in managing chronic kidney disease.
2. Calcium-Rich Foods
   • Interaction: Since Renolog Tablet can increase serum calcium levels, excessive consumption of calcium-rich foods or supplements might contribute to elevated calcium.
   • Effects: High calcium levels (hypercalcemia) can lead to nausea, vomiting, or other adverse symptoms.
   • Management: Monitor calcium intake and serum calcium levels regularly under medical supervision. Avoid unnecessary calcium supplementation or extremely high-calcium diets unless prescribed.
3. Alcohol Consumption
   • Interaction: Alcohol may potentially worsen kidney function or increase side effects during Renolog Tablet therapy.
   • Effects: Increased risk of dizziness, drowsiness, and reduced management effectiveness.
   • Management: Avoid alcohol or consult your doctor on safe practices regarding alcohol use while on Renolog Tablet.

Synopsis

More Information

01.Comparing Renolog’s ingredients, benefits, and administration with alternative supplements provide clarity and support confident purchasing decisions.

02.How Renolog Tablet Supports Kidney Function in Chronic Kidney Disease (CKD) and Nutritional Management

Renolog Tablet contains Alpha Ketoanalogues, which are nitrogen-free precursors of essential amino acids. This unique composition plays a key role in supporting kidney health, especially for individuals with chronic kidney disease (CKD), as follows:

• Nitrogen Recycling and Reduced Nitrogenous Waste:
  Alpha Ketoanalogues in Renolog utilize nitrogen from non-essential amino acids in the body to form essential amino acids without adding to the nitrogenous waste load. This process lowers the production and blood levels of urea and other toxic nitrogenous waste products, which tend to accumulate in CKD due to impaired kidney filtration. By reducing this toxic burden, Renolog helps ease the workload on damaged kidneys and preserves residual kidney function.
• Supports Protein Metabolism with Low-Protein Diets:
  Renolog is designed to be used alongside a low or very low protein diet, a common nutritional strategy in CKD management to limit nitrogen waste. The ketoanalogues supply the body with essential amino acids, helping maintain proper nutrition and metabolic balance without the need for high dietary protein, which would otherwise increase urea levels. This supplementation helps reduce malnutrition and muscle wasting often seen in CKD patients.
• Slows Progression of CKD:
  By minimizing the accumulation of toxic metabolites and supporting metabolic balance, Renolog contributes to slowing the progression of CKD. It reduces kidney strain by lowering the need for excessive nitrogen filtration and helps delay the onset of end-stage renal disease and the need for dialysis.
• Mechanism of Action Summary:
  After ingestion, the alpha ketoanalogues are converted into essential amino acids through the transfer of amino groups from non-essential amino acids. This transamination process does not generate additional nitrogenous waste, unlike normal amino acid metabolism. The intake of ketoanalogues therefore supports protein synthesis and metabolic needs without worsening nitrogenous burden or uremia.
• Additional Benefits:
  Regular monitoring, especially of serum calcium levels, is advised during Renolog therapy because the tablet contains calcium salts as carriers of the ketoanalogues. Taking it with food and avoiding certain antibiotic or calcium supplements ensures optimal absorption and efficacy.

Conclusion:
Renolog Tablet is a nutritional supplement that aids kidney function in CKD by providing essential amino acid precursors without increasing nitrogenous waste, supporting low-protein diets, improving protein metabolism, and helping to slow kidney disease progression. Its action is grounded in the science of nitrogen recycling and metabolic pathway modulation to reduce uremic toxins and preserve residual renal function.

FAQs About RENOLOG TABLET

References

1. Wu CH, Yang YW, Hung SC, Kuo KL, Wu KD, Wu VC, and Hsieh TC; National Taiwan University Study Group on Acute Renal Failure (NSARF). Ketoanalogues supplementation decreases dialysis and mortality risk in patients with anemic advanced chronic kidney disease. NIH, National Library of Medicine. National Center for Biotechnology Information. [Revised in 2017] [Accessed on 11th August 2025] 

2. Centaur Pharma Pvt. Ltd., NEFROGAURD. [Revised in January 2021] [Accessed on 11th August 2025]. 

3. La Renon Healthcare Pvt. Ltd. RENOLOG. [Revised in January 2021] [Accessed on 11th August 2025] 

Useful Diagnostic Tests

• Complete Blood Count (CBC)/ Hemogram
• Kidney Function Test (KFT)
• Kidney Profile (Kft) With Electrolytes
• Glomerular Filtration Rate (Gfr)

Author Details

Written By Dr. Karthikeyan Rajagopal - M.Pharm (Pharmacology)

Reviewed For Accuracy By Dr. Pushpraj Singh - MBBS

Last updated on 11 Aug 2025 | 04:52 PM(IST)