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Introduction About REFZIL O 250MG SUSPENSION
REFZIL O 250MG SUSPENSION is used in children for the management of bacterial infections such as bronchitis, respiratory tract infections (such as pneumonia), sinusitis, urinary tract infections, skin infections, ear infections, tonsils, throat infections, etc. It contains Cefprozil which is a cephalosporin antibiotic which works by killing the susceptible bacteria that causes the infection.
REFZIL O 250MG SUSPENSION should be used under careful medical supervision. It can be taken with or without meals. Do not skip doses or stop taking this medicine without consulting your doctor, even if your child feels better, as it could make the medicine less effective against complete eradication of the infections.
Before adminsitering REFZIL O 250MG SUSPENSION inform your doctor if your child is allergic to cephalosporin antibiotics, penicillins, cefdinir or similar medicines, have a previous history of developing severe diarrhea and stomach pain after taking antibiotics, is suffering from colitis or any kidney problems.
The most common side effects of taking REFZIL O 250MG SUSPENSION are nausea, vomiting, headache and dizziness. Consult your doctor if they trouble your child. Inform your doctor immediately if your child experiences severe stomach pain with blood diarrhea or fever, chills and flu-like symptoms after administering this medicine.
Uses Of REFZIL O 250MG SUSPENSION
Used in children for the management of bacterial infections such as:
- Bronchitis, sinusitis, tonsilitis, throat infections
- Respiratory tract infections (pneumonia)
- Skin infections
- Ear infections
How REFZIL O 250MG SUSPENSION Works
REFZIL O 250MG SUSPENSION contains Cefprozil which is a powerful antibiotic. It works by binding to the bacteria cell wall and inhibiting peptidoglycan synthesis, an essential component in bacterial cells that is required to keep cell wall stronger. This action, causes lysis of bacterial cell wall, disrupting cell components, followed by inactivation of the bacteria cells. Hence, Cefdinir is effective in managing severe bacterial infections.
How to use REFZIL O 250MG SUSPENSION
Administer REFZIL O 250MG SUSPENSION to your child as advised by your physician. It can be taken with or without meals.
Shake the bottle well to loosen the dry powder. Add the sterile water provided with this pack up to the ring mark present on the bottle surface. Add extra water if required to adjust the volume up to the ring mark. Close the bottle tightly and shake the mixture well.
Measure and consume the reconstituted mixture as advised by your doctor. Store the reconstituted mixture in refrigerator.
Your doctor will decide the correct dose and duration of therapy for your child depending upon your child’s age, body weight and severity of the infection.
Do not stop using REFZIL O 250MG SUSPENSION once the symptoms subside. It is important to complete course of therapy with REFZIL O 250MG SUSPENSION to achieve better control over the infection.
Side Effects Of REFZIL O 250MG SUSPENSION
Common
- Nausea, vomiting
- Mild diarrhea
- Stomach pain
- Headache, dizziness
- Vaginal itching or discharge
Stop administering REFZIL O 250MG SUSPENSION and consult your doctor immediately if your child experiences any of the following side effects such as:
- Allergic reactions (such as skin rashes, itching, swelling of lips, face, throat causing difficulty in breathing or swallowing)
- Severe blistering and peeling of skin with fever, sore throat
- Bloody diarrhea
- Chest pain, fever, chills, body aches, flu-like symptoms
How To Manage Side Effects
Nausea And Vomiting
Taking the antibiotic with food can help, as it can reduce stomach irritation. However, check if the specific antibiotic can be taken with food, as some require an empty stomach for proper absorption. Staying hydrated is essential; drinking small sips of water throughout the day can help ease nausea. Eating smaller, more frequent meals with bland, easy-to-digest foods like crackers, toast, or rice can also alleviate symptoms. Ginger, whether in tea or as a supplement, is known to help with nausea. If the nausea persists or worsens, it’s important to consult a healthcare provider, as they might adjust the dosage or switch to a different antibiotic.
Warning & Precautions
Kidney
Use with CautionREFZIL O 250MG SUSPENSION should be used with caution in children with kidney problems. Therefore, consult your doctor for advice before administration.
Allergy
ContraindicatedDo not administer REFZIL O 250MG SUSPENSION if your child is allergic to Cefprozil, penicillins or any other medicines of cephalosporin drug class.
Use In Pediatrics
ContraindicatedREFZIL O 250MG SUSPENSION should not be used in infants aged below 6 months, due to lack of safety data. Children aged above 6 months must use this medicine under medical supervision.
Others
Before administering REFZIL O 250MG SUSPENSION, inform your doctor if your child:
- Is chronically ill
- Have or have ever had gastrointestinal diseases such as ulcerative colitis
- Have phenylketonuria
Interactions
A. Drug-Drug Interactions:
- Aminoglycoside antibiotics (such as streptomycin, gentamicin, kanamycin)
- Probenecid (used for gout management)
- Iron supplements
Overdosage:
If your child or anyone else accidentally took too many doses of REFZIL O 250MG SUSPENSION, consult your doctor for advice immediately. Symptoms of overdosage might include nausea, vomiting, epigastric distress, diarrhea, and convulsions.
Synopsis
| Drug | : | Cefprozil |
| Pharmacological Category | : | Cephalosporin |
| Therapeutic Indication | : | Bacterial infections |
| Dosage Forms | : | Tablet, syrups, Oral drops |
FAQs About REFZIL O 250MG SUSPENSION
Q: What is REFZIL O 250MG SUSPENSION used for?
A: REFZIL O 250MG SUSPENSION is used in children for the management of bacterial infections such as bronchitis, respiratory tract infections (such as pneumonia), sinusitis, urinary tract infections, skin infections, ear infections, tonsils, throat infections, etc. It contains Cefprozil which is a cephalosporin antibiotic which works by killing the susceptible bacteria that causes the infection.
Q: How REFZIL O 250MG SUSPENSION works in the body?
A: REFZIL O 250MG SUSPENSION contains Cefdinir which is a powerful antibiotic. It works by binding to the bacteria cell wall and inhibiting peptidoglycan synthesis, an essential component in bacterial cells that is required to keep cell wall stronger. This action, causes lysis of bacterial cell wall, disrupting cell components, followed by inactivation of the bacteria cells. Hence, Cefdinir is effective in managing severe bacterial infections.
Q: Can I stop taking REFZIL O 250MG SUSPENSION once I feel better?
A: Follow the dosing schedule as advised by your physician to achieve better results. Do not skip doses or stop taking this medicine without consulting your doctor, even if you feel better, as it could make the medicine less effective against complete eradication of the infections.
Q: Is REFZIL O 250MG SUSPENSION safe?
A: REFZIL O 250MG SUSPENSION is safe when used under careful medical supervision. It may cause nausea, vomiting, stomach upset, headache or dizziness in some individuals. Therefore, consult your doctor for advice if they trouble you.
Q: When can I see an improvement in my condition after taking REFZIL O 250MG SUSPENSION?
A: It may take around 1-2 weeks of therapy to start noticing improvement. However, the therapy duration can take around 1 month or more based on the severity of infection.
Q: Can REFZIL O 250MG SUSPENSION be used in children?
A: REFZIL O 250MG SUSPENSION should not be used in infants aged below 6 months, due to lack of safety data. Children aged above 6 months must use this medicine under medical supervision.
References
1. KD. Tripathi. Essentials of Medical Pharmacology. 8th Edition. Beta-Lactam antibiotics. Page-777.
2. Cefprozil. A review of its antibacterial activity, pharmacokinetic properties, and therapeutic potential. NCBI. National Center for Biotechnology information. National library of Medicine. February 1993. [Accessed on 14th August 2024] https://pubmed.ncbi.nlm.nih.gov/7681376/
3. Cefprozil. National Library of Medicine. MedlinePlus. [Revised in January 2022]. [Accessed on 14th August 2024] https://medlineplus.gov/druginfo/meds/a698022.html
4. Sandoz Canada Inc. Cefprozil Tablets (cefprozil as cefprozil monohydrate). Tablets, 250 mg and 500 mg. [Revised in October 2020]. [Accessed on 14th August 2024] https://pdf.hres.ca/dpd_pm/00058690.PDF
5. Central Drugs Standard Control Organisation (CDSCO). Cefprozil tablet & powder for oral suspension. August 2006. Cefprozil 125mg/250mg Dispersible Tablet. June 2004. [Accessed on 14th August 2024] https://cdscoonline.gov.in/CDSCO/Drugs
Useful Diagnostic Tests
- Complete blood count (CBC)
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