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Torrent Pharmaceuticals Ltd

RANITIN 150 Tablet 40's

Ulcer/Reflux/Flatule...
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    Introduction About RANITIN 150 TABLET

    RANITIN 150 TABLET contains Ranitidine which belongs to the group of medicines called H2 receptor antagonists. It is used in the management of intestinal, benign and post-operative ulcers. Peptic or intestinal ulcers are open sores that develop on the inside lining of your stomach and the upper part of your small intestine, causing stomach pain.

    RANITIN 150 TABLET is also used to manage reflux oesophagitis (inflammation of lower food pipe due to backflow of acidic stomach contents) and Zollinger-Ellison Syndrome (small tumour in the first part of your intestine due to excessive gastrin secretion).

    Your doctor may occasionally perform tests to make sure RANITIN 150 TABLET is working and to manage side effects. Visit your doctor routinely for a check-up.

    Avoid smoking during the management with RANITIN 150 TABLET, as it may delay healing or worsen the ulcers. Before taking RANITIN 150 TABLET, inform your doctor if you have stomach cancer, kidney, lung or immunity problems, porphyria (rare blood disorder) or diabetes.

    RANITIN 150 TABLET is not recommended for use in pregnant or breastfeeding women unless your doctor finds it essential. For children, your doctor will determine a proper dose depending on your child’s age, body weight and disease condition. Contact your doctor if you experience any side effects or if any of the symptoms worsen.

    Uses Of RANITIN 150 TABLET

    Manage:

    • and manages intestinal, benign and post-operative ulcers
    • reflux oesophagitis
    • Zollinger-Ellison Syndrome

    How RANITIN 150 TABLET Works

    RANITIN 150 TABLET contains Ranitidine that works by reducing the amount of acid made by the stomach, which helps relieve pain and also allows healing of an ulcer or reflux disease.

    How to use RANITIN 150 TABLET

    Take RANITIN 150 TABLET as advised by your physician. Do not crush or chew it. Swallow RANITIN 150 TABLET as whole with a glass of water. Your doctor will decide the right dose and duration of therapy according to your age, body weight and disease condition. Do not stop taking RANITIN 150 TABLET unless your doctor advises you to stop.

    Side Effects Of RANITIN 150 TABLET

    Uncommon

    • stomach pain
    • constipation
    • nausea

    Rare

    • skin rashes
    • increase in serum creatinine levels (kidney function test)
    • changes in the liver function

    Stop taking RANITIN 150 TABLET and contact your doctor immediately if you experience any of the following side effects:

    • allergic reactions (rash, itching, hives, swelling of the face, lips, tongue or other body parts, chest pain, wheezing or breathing difficulties, feeling faint especially when standing up, unexplained fever)
    • kidney problems (changes in the amount and colour of urine you pass leading to back pain, fever, pain when urinating, blood in urine and changes in the blood test)
    • pancreatitis (severe stomach pain)
    • irregular or slow heartbeat
    • change in blood counts (unusual tiredness, breathlessness or tendency to infections or bruising)
    • pain or indigestion occurring during management
    • beginning to vomit blood or food
    • passing black (blood-stained) stools

    How To Manage Side Effects

    Nausea:

    Take RANITIN 150 TABLET with or just after meals. Stick to simple meals. Avoid eating oily or spicy foods. If symptom persists, contact your doctor.

    Constipation:

    Have plenty of fiber rich foods like fresh fruits, vegetables, cereals and drink ample amount of water. Exercise more regularly. If symptom persists, contact your doctor.

    Stomach pain:

    Try to rest and relax. Eat and drink slowly or try to eat smaller meals in small breaks. Keep a heat pad on your stomach. If symptom persists, contact your doctor.

    Skin rash:

    Avoid hot showers because hot water can further irritate your skin. Do not scratch the affected area. Use protective clothing when going outdoors. Regularly moisturize your skin. Consult your doctor if your skin rash persists.

    Warning & Precautions

    Pregnancy

    RANITIN 150 TABLET is not recommended for use in pregnant women unless considered clearly necessary. Consult your doctor before taking it.

    Breastfeeding

    RANITIN 150 TABLET is not recommended for use in breastfeeding women unless considered clearly necessary. Consult your doctor before taking it.

    Driving and Using Machines

    RANITIN 150 TABLET has no or negligible effect on driving or using any heavy machineries.

    Kidney

    RANITIN 150 TABLET should be taken with caution in patients with kidney problems. Consult your doctor before taking it.

    Liver

    RANITIN 150 TABLET should be taken with caution in patients with liver disease. Consult your doctor before taking it.

    Allergy

    Do not take RANITIN 150 TABLET if you are allergic to Ranitidine or any of the other ingredients of this medicine.

    Lungs

    RANITIN 150 TABLET should be taken with caution in patients with lung disease, cough or chest infection. Consult your doctor before taking it.

    Others

    Before taking RANITIN 150 TABLET, inform your doctor if you:

    • have a history of stomach ulcers
    • have stomach cancer
    • have acute porphyria (a rare genetic condition)
    • have diabetes (high blood sugar)
    • have problems with your immune system

    Use in paediatrics:

    Your doctor will prescribe the right dose of RANITIN 150 TABLET depending on age, body weight and health condition of your child. Consult your child’s doctor for advice.

    Use in geriatrics:

    RANITIN 150 TABLET should be used with caution in elderly patients (aged above 65 years). Consult your doctor before taking it.

    Interactions

    A. Drug - Drug interactions:

    Before taking RANITIN 150 TABLET, inform your doctor if you are taking any of the following medicines:

    • medicines used to reduce pain and inflammation (Ex. aspirin, ibuprofen, naproxen)
    • lidocaine (used to make you feel insensitive to pain)
    • medicines used to manage heart problems (Ex. propranolol, procainamide, n-acetylprocainamide)
    • diazepam (used for worrying or anxiety problems)
    • phenytoin (used to manage fits)
    • theophylline (used to manage breathing problems)
    • warfarin (used to manage blood clots)
    • glipizide (used to reduce blood glucose levels)
    • medicines used to manage HIV infection (Ex. atazanavir, delavirdine)
    • gefitinib (used in lung cancer management)
    • medicines used to manage fungal and yeast infections (Ex. itraconazole, ketoconazole)
    • sucralfate (used to manage intestinal ulcers)
    • medicines used to produce sleepiness and drowsiness during surgeries or to manage insomnia (Ex. midazolam, triazolam)

    Overdosage:

    If you or anyone else accidentally take too much of RANITIN 150 TABLET, consult your doctor immediately or visit the nearby hospital.

    Synopsis

    Drug :   Ranitidine
    Pharmacological Category :   H2 receptor antagonist
    Therapeutic Indication :   Peptic ulcers, reflux oesophagitis,Zollinger-Ellison Syndrome
    Dosage Forms :   Tablet, Capsule, Injection, Liquid, Oral solution, Syrup

    More Information

    • Keep RANITIN 150 TABLET out of reach of children
    • Do not store RANITIN 150 TABLET above 25°C

    FAQs About RANITIN 150 TABLET

    Is RANITIN 150 TABLET good for acid reflux?

    Yes. RANITIN 150 TABLET heals and stops problems caused by acid in the food pipe or too much acid in the stomach and thus relieves acid reflux or heartburn. Consult your doctor for further queries.

    Can I stop taking RANITIN 150 TABLET on my own?

    If you suddenly stop taking RANITIN 150 TABLET the symptoms that existed before the management may return. It is always better to consult your physician before stopping the medicine, even if you feel better.

    Can RANITIN 150 TABLET cause erectile dysfunction?

    Certain acid reflux medicines (H2 blockers) can also affect histamine and cause erectile dysfunction. Whereas some medicines of this class have the highest risk for ED, RANITIN 150 TABLET have a lower risk. Consult your doctor for further queries.

    Can I receive RANITIN 150 TABLET before an operation?

    Before undergoing any operation, inform your doctor if you are receiving RANITIN 150 TABLET. This is because the doctor or surgeon can give you midazolam to make you fall asleep before operation and it can interact with RANITIN 150 TABLET. Consult your doctor for further queries.

    What if I forget to take a dose of RANITIN 150 TABLET?

    Doubling the dose of RANITIN 150 TABLET to make up for a forgotten dose would not substitute the missing amount but increase the risk of overdosing. Continue the management according to the schedule. If there are any further questions on the use of this medicine, call your doctor.

    References

    1. KD Tripathi. Gastrointestinal Drugs. Essentials of Medical Pharmacology. Eighth Edition, 2019. Page – 698.

    2. Morgan KA, Ahlawat R. Ranitidine. NIH: National Library of Medicine, National center of biotechnology Information. StatPearls [Internet]. December 2021. [Accessed on 27th October 2022] https://www.ncbi.nlm.nih.gov/books/NBK532989/

    3. Yeomans, N. D., Svedberg, L. E., & Naesdal, J. Is ranitidine therapy sufficient for healing peptic ulcers associated with non-steroidal anti-inflammatory drug use? NIH National Library of Medicine, National center for biotechnology information. Pubmed Central. November 2006. [Accessed on 27th October 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1636688/

    4. Accord Healthcare Limited. Electronic Medicines Compendium (EMC). [Revised in August 2014] [Accessed on 27th October 2022] https://www.medicines.org.uk/emc/files/pil.6040.pdf

    5. GlaxoSmithKline Bangladesh Limited. Zantac (Ranitidine hydrochloride). [Revised in February 2013] [Accessed on 27th October 2022] https://gskpro.com/content/dam/global/hcpportal/en_BD/PI/Zantac_Tablet_1_03_2019.pdf

    6. Apotex Pty Ltd. APO-Ranitidine (Ranitidine hydrochloride tablet). [Revised in March 2019] [Accessed on 27th October 2022] https://media.healthdirect.org.au/medicines/GuildLink_Information/122014/CMI/txcranit10319.pdf

    Useful Diagnostic Tests

    • Urea breath test
    • Upper GI endoscopy

    Author Details

    Written By Dr. Jeenal Rajani - Pharm.D.
    Reviewed For Accuracy By Dr. Vrushabhakumar Jitendra Shah. - MBBS
    Last updated on 07 Nov 2022 | 05:24 PM(IST)
    Lab updated