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Eisai Pharmaceuticals India Pvt Ltd

QUICOBAL Oral Disintegrating Strips 1's

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    Introduction About QUICOBAL ORAL DISINTEGRATING STRIPS

    QUICOBAL ORAL DISINTEGRATING STRIPS contains Methylcobalamin, which belongs to the group of medicines called Vitamins. QUICOBAL ORAL DISINTEGRATING STRIPS is used to manage peripheral neuropathies (peripheral nerve damage that affects hands, feet, and arms) and megaloblastic anaemia (blood disorder that occurs due to abnormal production of red blood cells) caused by vitamin B12 deficiency in affected individuals.

    QUICOBAL ORAL DISINTEGRATING STRIPS is not recommended for use in patients allergic to mecobalamin and/or other B12-containing medicines. It is also not recommended for use in patients with Leber’s disease (an inherited form of vision loss).

    Before taking QUICOBAL ORAL DISINTEGRATING STRIPS, inform your doctor if you are in an occupation of handling mercury and/or have kidney problems (such as renal failure) or liver problems (such as hepatic impairment).

    QUICOBAL ORAL DISINTEGRATING STRIPS is not recommended for use in pregnant and breastfeeding women. It should be used with caution in children and adolescents (aged 6 months to 18 years) and is advised to be used with caution in elderly patients (aged 65 years and above) after consulting the doctor.

    The most common side effects of taking QUICOBAL ORAL DISINTEGRATING STRIPS are weakness, headache, back pain, muscle pain, indigestion, nausea, and/or vomiting. Consult your doctor if any of these side effects worsen.

    Uses Of QUICOBAL ORAL DISINTEGRATING STRIPS

    • Manage peripheral neuropathies
    • Manage megaloblastic anaemia (caused by vitamin B12 deficiency) in affected individuals

    How QUICOBAL ORAL DISINTEGRATING STRIPS Works

    QUICOBAL ORAL DISINTEGRATING STRIPS works by aiding in the synthesis of myelin (a lipid-rich material that covers nerve fibers), which helps in protecting the nerve fibers and thereby providing relief from painful diabetic neuropathy in affected individuals. It also promotes nucleic acid synthesis in the bone marrow, which helps in the maturation and division of erythroblasts, thus managing poor production of red blood cells and thereby improving megaloblastic anemia in affected individuals.

    How to use QUICOBAL ORAL DISINTEGRATING STRIPS

    Tablet:

    Take QUICOBAL ORAL DISINTEGRATING STRIPS as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight, and disease condition.

    Oral Disintegrating Tablet:

    Take QUICOBAL ORAL DISINTEGRATING STRIPS as advised by your physician. Place QUICOBAL ORAL DISINTEGRATING STRIPS inside your mouth and allow it to dissolve completely. Do not swallow or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight, and disease condition.

    Sublingual Tablet:

    Take QUICOBAL ORAL DISINTEGRATING STRIPS as advised by your physician. Place QUICOBAL ORAL DISINTEGRATING STRIPS under the tongue till it dissolves. Your doctor will decide the correct dose and duration for you depending upon your age, body weight, and disease condition.

    Side Effects Of QUICOBAL ORAL DISINTEGRATING STRIPS

    Common

    • Weakness, headache, back pain, generalized pain, muscle pain
    • Infection
    • Indigestion, nausea, vomiting, diarrhea
    • Swollen tongue, burning/prickling sensation
    • Anorexia (eating disorder)
    • Rash

    How To Manage Side Effects

    Diarrhea

    Drink plenty of water and stay hydrated. Try to avoid taking any medicine on your own to manage diarrhea. Consult your doctor if diarrhea worsens.

    Headache

    If QUICOBAL ORAL DISINTEGRATING STRIPS causes headache, then take rest and drink plenty of fluids. Try to avoid drinking alcohol. Ask your doctor to recommend a painkiller. Headaches should usually go away after the first week of taking QUICOBAL ORAL DISINTEGRATING STRIPS. Consult your doctor if a headache persists.

    Indigestion

    Try to have smaller and more frequent meals and drink slowly. Reduce consumption of coffee, cola, tea, or alcohol and lose weight if you are obese. Try to avoid smoking and don’t have rich, fatty, or spicy foods. Consult your doctor if the digestion does not improve.

    Nausea And Vomiting

    Take QUICOBAL ORAL DISINTEGRATING STRIPS with or just after a meal. Stick to simple meals. Avoid eating oil-rich or spicy foods, sugary snacks, and drinks. Avoid drinking too much liquid along with your meals, drink slowly in between meals. Talk with your doctor if the nausea and vomiting worsen.

    Warning & Precautions

    Pregnancy

    Contraindicated

    QUICOBAL ORAL DISINTEGRATING STRIPS is not recommended for use in pregnant women. Consult your doctor before taking QUICOBAL ORAL DISINTEGRATING STRIPS.

    Breastfeeding

    Contraindicated

    QUICOBAL ORAL DISINTEGRATING STRIPS is not recommended for use in breastfeeding women. Consult your doctor before taking QUICOBAL ORAL DISINTEGRATING STRIPS.

    Kidney

    Use with Caution

    QUICOBAL ORAL DISINTEGRATING STRIPS should be used with caution in patients with kidney problems such as renal failure. Consult your doctor before taking the medicine.

    Liver

    Use with Caution

    QUICOBAL ORAL DISINTEGRATING STRIPS should be used with caution in patients with liver problems such as hepatic impairment. Consult your doctor before taking the medicine.

    Allergy

    Contraindicated

    Do not take QUICOBAL ORAL DISINTEGRATING STRIPS if you are allergic to mecobalamin, other B12-containing medicines, and/or any other ingredients of this medicine.

    Use In Pediatrics

    Use with Caution

    QUICOBAL ORAL DISINTEGRATING STRIPS should be used with caution in children and adolescents (aged 6 months to 18 years). Consult your doctor before administering the medicine to the child.

    Use In Geriatrics

    Use with Caution

    QUICOBAL ORAL DISINTEGRATING STRIPS should be used with caution in elderly patients (aged above 65 years). Consult your doctor before taking the medicine.

    Others

    QUICOBAL ORAL DISINTEGRATING STRIPS is not recommended for use if you:

    • Have Leber’s disease (an inherited form of vision loss)

    Before taking QUICOBAL ORAL DISINTEGRATING STRIPS, inform your doctor if you: 

    • Are in an occupation of handling mercury

    Interactions

    A. Drug-Drug interactions:

    Before taking QUICOBAL ORAL DISINTEGRATING STRIPS, inform your doctor if you are taking any of the following medicine:

    • Neomycin (used to manage bacterial skin infections)
    • Amino salicylic acid (used to manage tuberculosis)
    • Histamine H2-antagonists (used to manage recurrence of duodenal ulcers) Ex. ranitidine, famotidine 
    • Colchicine (used in the management of gout)
    • Oral contraceptives (used to manage pregnancy) Ex. ethinyl estradiol and norethindrone
    • Chloramphenicol (used to manage bacterial infections)
    • Omeprazole (used to manage gastric and duodenal ulcers, erosive esophagitis, and gastroesophageal reflux disease)

    Overdosage:

    If you or anyone else accidentally takes too much of QUICOBAL ORAL DISINTEGRATING STRIPS, consult your doctor immediately or visit the nearby hospital to manage overdose symptoms.

    Synopsis

    Drug :   Mecobalamin
    Pharmacological Category :   Vitamin B12
    Therapeutic Indication :   Peripheral neuropathy, Megaloblastic anaemia
    Dosage Forms :   Tablet, Oral disintegrating strip, Injection, Nasal spray

    More Information

    Storage

    • Keep QUICOBAL ORAL DISINTEGRATING STRIPS out of reach of children
    • Store QUICOBAL ORAL DISINTEGRATING STRIPS below 30°C

    FAQs About QUICOBAL ORAL DISINTEGRATING STRIPS

    Q: What is QUICOBAL ORAL DISINTEGRATING STRIPS used for?

    A: QUICOBAL ORAL DISINTEGRATING STRIPS is used to manage peripheral neuropathies (peripheral nerve damage that affects hands, feet, and arms) and megaloblastic anaemia (blood disorder that occurs due to abnormal production of red blood cells), which occurs due to deficiency of vitamin B12 in affected individuals.

    Q: How QUICOBAL ORAL DISINTEGRATING STRIPS be taken?

    A: For Tablet: Take QUICOBAL ORAL DISINTEGRATING STRIPS as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight, and disease condition.

    For Oral Disintegrating Tablet: Take QUICOBAL ORAL DISINTEGRATING STRIPS as advised by your physician. Place QUICOBAL ORAL DISINTEGRATING STRIPS inside your mouth and allow it to dissolve completely. Do not swallow or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight, and disease condition.

    For Sublingual Tablet:

    Take QUICOBAL ORAL DISINTEGRATING STRIPS as advised by your physician. Place QUICOBAL ORAL DISINTEGRATING STRIPS under the tongue till it dissolves. Your doctor will decide the correct dose and duration for you depending upon your age, body weight, and disease condition.

    Q: What are the side effects of QUICOBAL ORAL DISINTEGRATING STRIPS?

    A: The most common side effects of taking QUICOBAL ORAL DISINTEGRATING STRIPS are weakness, headache, back pain, muscle pain, indigestion, nausea, and/or vomiting. Consult your doctor if any of these side effects worsen.

    Q: How QUICOBAL ORAL DISINTEGRATING STRIPS works?

    A: QUICOBAL ORAL DISINTEGRATING STRIPS works by aiding in the synthesis of myelin (lipid-rich material that covers nerve fibers), which helps in protecting the nerve fibers and thereby providing relief from painful diabetic neuropathy in affected individuals. It also promotes nucleic acid synthesis in the bone marrow, which helps in the maturation and division of erythroblasts, thus managing poor production of red blood cells and thereby improving megaloblastic anaemia in affected individuals.

    Q: Can QUICOBAL ORAL DISINTEGRATING STRIPS be used in pregnant and breastfeeding women?

    A: No, QUICOBAL ORAL DISINTEGRATING STRIPS is not recommended for use in pregnant and breastfeeding women since it may cause some undesirable effects to the foetus and breastfed baby. Consult your doctor before taking QUICOBAL ORAL DISINTEGRATING STRIPS.

    Q: Is QUICOBAL ORAL DISINTEGRATING STRIPS safe for kids?

    A: QUICOBAL ORAL DISINTEGRATING STRIPS should be used with caution in children and adolescents (aged 6 months to 18 years). Consult your doctor before administering the medicine to the child.

    Q: What precautions must be taken while using QUICOBAL ORAL DISINTEGRATING STRIPS?

    A: QUICOBAL ORAL DISINTEGRATING STRIPS should be used with caution in patients with kidney problems such as renal failure and liver problems such as hepatic impairment. Consult your doctor before taking the medicine.

    Q: Who should not take QUICOBAL ORAL DISINTEGRATING STRIPS?

    A: QUICOBAL ORAL DISINTEGRATING STRIPS is not recommended for use if you have Leber’s disease (inherited form of vision loss), are allergic to mecobalamin, or are taking other B12-containing medicines.

    Q: Can I take QUICOBAL ORAL DISINTEGRATING STRIPS daily?

    A: Always take QUICOBAL ORAL DISINTEGRATING STRIPS as advised by your doctor. Do not take more than the recommended daily dose. Your doctor will decide the correct dose and duration for you depending upon your age, body weight, and disease condition.

    Q: Is QUICOBAL ORAL DISINTEGRATING STRIPS good for nerves?

    A: QUICOBAL ORAL DISINTEGRATING STRIPS is a form of vitamin B12 that helps in the production of DNA, RNA, and proteins. It also helps regenerate nerves and aids in the formation of lecithin, which helps repair damaged nerves.

    References

    1. KD. Tripathi. Drugs affecting blood and blood formation, Vitamins. Essentials of Medical Pharmacology. Seventh Edition. 2013. Page – 606.

    2. Advait Vasavada; Devang Sanghavi. Cyanocobalamin.  NIH National Library of Medicine. National Center for Biotechnology Information. StatPearls [Internet]. September 2022. [Accessed on 2nd August 2024] https://www.ncbi.nlm.nih.gov/books/NBK555964/

    3. A S M Al Amin; Vikas Gupta. Vitamin B12 (cobalamin).  NIH National Library of Medicine. National Center for Biotechnology Information. StatPearls [Internet]. June 2022. [Accessed on 2nd August 2024] https://www.ncbi.nlm.nih.gov/books/NBK559132/

    4. Rabia G. Sezer, Abdulkadir Bozaykut, Handan A. Akoglu, and Gül N. Özdemir. The Efficacy of Oral Vitamin B12 Replacement for Nutritional Vitamin B12 Deficiency. NIH National Library of Medicine. National Center for Biotechnology Information. PubMed.gov. March 2018. [Accessed on 2nd August 2024] https://pubmed.ncbi.nlm.nih.gov/29189512/

    5. Emmanuel Andrès, Thomas Vogel, Laure Federici, Jacques Zimmer, Ecaterina Ciobanu, and Georges Kaltenbach. Cobalamin Deficiency in Elderly Patients: A Personal View. NIH National Library of Medicine. National Center for Biotechnology Information. PMC PubMed Central. May 2008. [Accessed on 2nd August 2024] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2672039/

    6. Getz Pharma (Pvt) Ltd. Nervon. [Accessed on 2nd August 2024] https://getzpharma.com/wp-content/uploads/2016/08/Nervon-Range-Leaflet-Export-GA.pdf

    7. Mova Pharmaceutical Pvt Ltd. MOVACOBAL MD 3. [Accessed on 2nd August 2024] http://movapharma.com/cod-division.php

    8. Micro Labs Ltd. Meconerv Tablet. [Accessed on 2nd August 2024] https://www.microlabsltd.com/elibrary/node/1908

    9. Kivonyx Healthcare. Vibicol SL. [Accessed on 2nd August 2024] https://www.kivonyx.com/product/Vibicol-SL

    Useful Diagnostic Tests

    • Nerve conduction test 
    • Complete Blood Count (CBC)/ Hemogram
    • Vitamin B-12
    • Complete Vitamins Profile
    • Healthy Midlife Checkup
    • Men Health Checkup - Advanced
    • Complete Women Checkup
    • Women Health Checkup - Essential
    • Full Body Checkup – Gold
    • Full Body Checkup – Silver

    Author Details

    Written By Dr. N. Sai Swaroop - Pharm.D
    Reviewed For Accuracy By Dr. Shruthi Raikar - BDS
    Last updated on 05 Aug 2024 | 04:44 PM(IST)
    Lab updated