Prolop Infusion 100ml
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Introduction About PROLOP INFUSION
PROLOP INFUSION contains Paracetamol which belongs to the group of medicines called Analgesics and Antipyretics. It is used for short-term management of moderate pain (especially after surgery) and fever when administered by the intravenous route is clinically justified.
Before receiving PROLOP INFUSION, inform your doctor if you have heart, lung, liver or kidney problems or if you suffer from alcoholism or alcohol abuse, malnourishment and severely low blood volume due to dehydration or blood loss.
PROLOP INFUSION should be used with caution in pregnant and breastfeeding women only if clearly advised by the doctor. PROLOP INFUSION should be used with caution in children and elderly patients.
The most common side effects of receiving PROLOP INFUSION are nausea, vomiting, headache, sleep problems and itching. Inform your doctor if any of these side effect worsens.
Uses Of PROLOP INFUSION
- For short-term management of moderate pain (especially after surgery) and fever
How PROLOP INFUSION Works
PROLOP INFUSION relieves pain by increasing the pain threshold by inhibiting certain enzymes (COX-1 and COX-2) involved in the synthesis of chemicals responsible for inducing pain (prostaglandins). It reduces fever by directly acting on heat-regulating centers in the brain, resulting in vessel relaxation, sweating and loss of body heat.
How to use PROLOP INFUSION
PROLOP INFUSION will be given to you only by a doctor or a nurse into the vein as an intravenous infusion. Your doctor will decide the correct dose and duration for you based on your age, body weight and disease condition.
Side Effects Of PROLOP INFUSION
Common
- nausea, vomiting, constipation
- headache
- sleep problems
- itching
Rare
- feeling generally unwell
- drop in blood pressure
- abnormal levels of liver enzymes
Inform your doctor immediately if you experience any of the following side effects while receiving PROLOP INFUSION:
- serious allergic reaction or skin rash
How To Manage Side Effects
Constipation
Try to eat more high-fibre foods such as fresh fruit, vegetables, cereals and drink plenty of water. If this does not help, inform your doctor to receive alternate management for constipation.
Headache
Drink ample amount of water and avoid skipping meals. Get adequate rest. Try to be relaxed and stress-free. Apply pain relieving balm on your forehead if necessary. Inform your doctor if the symptom does not improve.
Nausea And Vomiting
Stick to simple meals while receiving this medicine. Avoid eating oily rich, fried or spicy foods. Do not lie down or sleep immediately after eating. Inform your doctor if the symptom does not improve.
Warning & Precautions
Pregnancy
Monitoring requiredPROLOP INFUSION should be used with caution in pregnant women only if considered clearly necessary. Your doctor may use the lowest possible dose to reduce the pain and fever only for shorter duration in pregnant women. Consult your doctor before receiving it.
Breastfeeding
Monitoring requiredPROLOP INFUSION can be used in breastfeeding women only if considered clearly necessary. Consult your doctor before receiving it.
Alcohol
Consult your doctorPROLOP INFUSION should be used with caution in patients with alcoholism or those who suffer from alcohol abuse.
Kidney
Use with CautionPROLOP INFUSION should be used with caution in patients with kidney disease. Consult your doctor before receiving it.
Liver
Consult your doctorPROLOP INFUSION is not recommended for use in patients with severe liver disease. It should be used with caution in patients with liver disease. Consult your doctor before receiving it.
Allergy
ContraindicatedDo not receive PROLOP INFUSION if you are allergic to Paracetamol, propacetamol or any other ingredients of this medicine.
Lungs
ContraindicatedRepeated use of PROLOP INFUSION is not recommended for use in patients with lung disease. Consult your doctor before receiving it.
Use In Pediatrics
Use with CautionPROLOP INFUSION should be used with caution in children and your child’s doctor may adjust the dose depending upon the child’s age and body weight. Consult your child’s doctor for advice before administration of PROLOP INFUSION.
Use In Geriatrics
Use with CautionPROLOP INFUSION should be used with caution in elderly patients. Consult your doctor before receiving it.
Others
PROLOP INFUSION is not recommended for use if you:
- have anaemia
Before receiving PROLOP INFUSION, inform your doctor if you:
- have severe hypovolemia (low blood volume due to dehydration or blood loss)
- have chronic malnutrition
Interactions
A. Drug-Drug interactions:
Before receiving PROLOP INFUSION, inform your doctor if you are taking any of the following medicines:
- other medicines containing paracetamol or propacetamol
- probenecid (used to manage gout)
- medicines used for blood thinning (Ex. warfarin)
Overdosage:
PROLOP INFUSION will be administered to you only by a doctor or a nurse in a hospital and so it is unlikely to receive an overdose. However, consult your doctor if you experience any unusual symptoms such as nausea, vomiting, anorexia (eating disorder), paleness, stomach pain and a risk of liver injury.
Synopsis
| Drug | : | Paracetamol |
| Pharmacological Category | : | Para aminophenol derivative |
| Therapeutic Indication | : | Pain, Fever |
| Dosage Forms | : | Tablet, Dispersible tablet, Drops, Syrup, Oral suspension, Liquid, Oral solution, Suppositories, Infusion, Injection |
More Information
Storage
- Store below 25°C
FAQs About PROLOP INFUSION
Q: What is PROLOP INFUSION used for?
A: PROLOP INFUSION is used for short-term management of moderate pain (especially after surgery) and fever and when administered by the intravenous route is clinically justified. Consult your doctor for advice before administration of PROLOP INFUSION.
Q: What should I tell my doctor before receiving PROLOP INFUSION?
A: Patients receiving PROLOP INFUSION must inform their doctor about pre-existing conditions like heart, lung, liver or kidney problems, alcoholism, malnourishment or dehydration. Patients should also inform the doctor if they are pregnant, breastfeeding or allergic to anything. Inform your doctor if you experience any unusual symptoms during management with this medicine.
Q: Can PROLOP INFUSION be used during pregnancy?
A: PROLOP INFUSION should be used with caution in pregnant women only if clearly advised by the doctor. Your doctor may use the lowest possible dose to reduce the pain and fever only for a shorter duration in pregnant women. Consult your doctor before receiving PROLOP INFUSION.
Q: How does PROLOP INFUSION work?
A: PROLOP INFUSION relieves pain by increasing the pain threshold by inhibiting certain enzymes (COX-1 and COX-2) involved in the synthesis of chemicals responsible for inducing pain (prostaglandins). It reduces fever by directly acting on heat-regulating centers in the brain, resulting in vessel relaxation, sweating and loss of body heat.
Q: Is PROLOP INFUSION safe to use in patients with liver disease?
A: PROLOP INFUSION is not recommended for use in patients with severe liver disease. It should be used with caution in patients with liver disease. Your doctor may monitor your liver function test before and during management with this medicine to manage the risk of liver damage. Consult your doctor before receiving PROLOP INFUSION.
References
1. Tilo Grosser, Emer Smyth and Garret A. FitzGerald. Anti-inflammatory, Antipyretic and Analgesic agents; Pharmacotherapy of gout. Goodman & Gilman’s: The Pharmacological basics of Therapeutics. 12th Edition. New York McGraw Hill Medical 2011. Page-693.
2. KD. Tripathi. NSAIDs and Antipyretic-Analgesics. Essentials of Medical Pharmacology. Seventh edition. 2013. Page-206.
3. Ulderico Freo, Chiara Ruocco, Alessandra Valerio, Irene Scagnol and Enzo Nisoli. Paracetamol: A Review of Guideline Recommendations. NIH National Library of Medicine, National center for biotechnology information. PubMed Central. August 2021. [Accessed on 16th August 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8347233/
4. Olivier Malaise, Olivier Bruyere and Jean-Yves Reginster. Intravenous paracetamol: A review of efficacy and safety in therapeutic use. ResearchGate. November 2007. [Accessed on 16th August 2022] https://www.researchgate.net/publication/247872458_Intravenous_paracetamol_A_review_of_efficacy_and_safety_in_therapeutic_use
5. Altan Pharmaceutical. Electronic Medicines Compendium (EMC). [Revised in December 2021] [Accessed on 16th August 2022] https://www.medicines.org.uk/emc/files/pil.13649.pdf
6. B. Braun Medical Inc. U.S. Food & Drug Administration. [Revised in February 2021] [Accessed on 16th August 2022] https://www.accessdata.fda.gov/drugsatfda_docs/label/2021/204957s000lbl.pdf
7. Therapeutic Pharmaceuticals. Aeknil injection (Paracetamol). [Revised in May 2016] [Accessed on 16th August 2022] https://aeknil.com/pi/aekinj.pdf
8. Central Drugs Standard Control Organization (CDSCO). Paracetamol. [Accessed on 16th August 2022] https://cdscoonline.gov.in/CDSCO/Drugs
Useful Diagnostic Tests
- Complete blood count
- Liver function test
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