Prolomet AM 50mg Tablet 10'S

Introduction About PROLOMET AM 50MG TABLET

What is Prolomet AM 50mg Tablet 10'S?

Prolomet AM 50mg Tablet is a combination of Amlodipine and Metoprolol commonly used to manage high blood pressure and heart-related conditions such as angina pectoris. By relaxing blood vessels and supporting heart function, this tablet helps maintain optimal blood flow and supports cardiovascular health.

During management with Prolomet AM 50mg Tablet, practice regular exercise (such as walking), eating healthy and salt-restricted diet and managing weight will also help to control your blood pressure effectively. Avoid taking grapefruit or its juice while taking Prolomet AM 50mg Tablet as it may increase the blood pressure lowering effect of this medicine.

Take Prolomet AM 50mg Tablet at the same time each day, with or without food, as advised by your healthcare provider. Swallow the tablet whole with a glass of water. Do not crush, chew, or break it. Maintain a healthy lifestyle, regular exercise, balanced diet, and weight management can further support your heart health.

Consult your doctor before starting Prolomet AM 50mg Tablet, if you have liver, kidney, or respiratory conditions, or if you are pregnant or breastfeeding. Avoid grapefruit or grapefruit juice while taking this medicine, as it may increase side effects. Regular monitoring of blood pressure and kidney function may be recommended during use. Do not stop taking the medicine abruptly without consulting your healthcare provider

The most common side effects of taking Prolomet AM 50mg Tablet are headache, dizziness, or tiredness, nausea, abdominal pain, or constipation, slow heart rate, ankle swelling, or flushing, sleepiness or muscle cramps. Most side effects are mild and temporary, consult your doctor if persistent.

Uses Of PROLOMET AM 50MG TABLET

Used to manage,

• high blood pressure
• heart-related conditions such as angina pectoris

Key Features of Prolomet AM 50mg Tablet

• Combination of Amlodipine (5mg) and Metoprolol (50mg)
• Supports healthy blood pressure levels
• Helps reduce the workload on the heart
• Promotes better blood circulation
• Convenient once-daily dosage

Benefits of PROLOMET AM 50MG TABLET

1. Dual-Action Formula for Cardiovascular Support

• Combines two widely recommended medicines, amlodipine (a calcium channel blocker) and metoprolol (a beta-blocker) to help improve blood vessel relaxation and reduce the heart's workload
• This synergy supports smoother blood flow and more efficient heart function.

2. Consistent Blood Pressure Control

• Helps maintain healthy blood pressure throughout the day, contributing to improved overall cardiovascular stability
• The dual medicine formulation addresses both systolic and diastolic blood pressure, offering more comprehensive support

3. Enhanced Exercise Tolerance & Activity Support

• By enabling better control of heart rate and blood pressure, the tablet can help users participate more comfortably in daily activities and light exercise without undue cardiac strain
• This benefit is particularly valuable for urban patients with active or stressful lifestyles

4. Convenient Once-Daily Dosing

• Designed for easy, once-daily intake, which aids in routine adherence and better patient compliance

How PROLOMET AM 50MG TABLET Works

Mechanism of Action of Prolomet AM 50mg Tablet

Prolomet AM helps to reduce high blood pressure, where Amlodipine works by inhibiting the movement of calcium ions into both vascular smooth muscle and cardiac muscle resulting in lower blood pressure by relaxing the blood vessels and improving the flow of blood to the heart muscles. Metoprolol works by reducing the force of contraction of the heart muscles by the blocking the effects of certain hormones called adrenaline and making the heart to beat more easily thus it lowers the blood pressure.

How Prolomet AM 50mg Tablet Supports Blood Flow

• Relaxation of Blood Vessels (Vasodilation)
• Reduced Heart Workload
• Improved Oxygen Supply to the Heart
• Comprehensive Cardiovascular Support

How to use PROLOMET AM 50MG TABLET

• Take the tablet at the same time each day, with or without food, as advised by your healthcare provider
• Swallow the tablet whole with a glass of water
• Do not crush, chew, or break the medicine
• Maintain a healthy lifestyle like regular exercise, balanced diet, and weight management can further support your heart health

Recommended Dosage of Prolomet AM 50mg Tablet

Typical Adult Dosage:

The usual recommended dosage for adults is one tablet (50mg metoprolol + 5mg amlodipine) taken once daily. However, the exact dose and duration should always be determined by your healthcare provider based on your specific condition, response to therapy, and medical history.

Adjustment Needs:

Lower starting doses may be recommended for elderly patients or those with certain pre-existing conditions, such as liver or kidney problems.

What if I forgot to take PROLOMET AM 50MG TABLET

• Take the missed dose as soon as you remember
• If it is almost time for your next scheduled dose, skip the missed one, do not take two doses at the same time or within close proximity
• Resume your regular dosing schedule

Overdose

• If you or anyone else accidentally takes too much of PROLOMET AM 50MG TABLET, consult your doctor immediately or visit the nearby hospital
• Overdosage symptoms of PROLOMET AM 50MG TABLET are low blood pressure (fatigue and dizziness), slow pulse, heart conduction problems, shortness of breath, unconsciousness, nausea and vomiting, blue colouring of the skin, low blood sugar levels and high levels of potassium in the blood

Side Effects Of PROLOMET AM 50MG TABLET

Common

• headache
• dizziness
• tiredness
• nausea
• abdominal pain
• constipation
• slow heart rate
• ankle swelling
• flushing
• sleepiness
• muscle cramps

When to consult a doctor?

• allergic reaction (such as itching, difficulty breathing or swelling of the face, lips, throat or tongue)
• wheeziness, chest pain, shortness of breath or difficulty in breathing
• severe skin reactions including intense skin rash, hives, reddening of the skin over the whole body, severe itching, blistering, peeling and swelling of the skin, inflammation of mucous membranes (stevens johnson syndrome, toxic epidermal necrolysis) or other allergic reaction
• abnormal heartbeat
• inflamed pancreas which may cause severe abdominal and back pain accompanied with feeling very unwell

How To Manage Side Effects

Headache

Drink ample amount of water and avoid skipping meals. Get adequate rest. Try to be relaxed and stress free. Apply pain relieving balm on your forehead if necessary.

Nausea And Vomiting

Stick to simple meals while taking this medicine. Avoid eating oily rich, fried or spicy foods. Do not lie down or sleep immediately after eating

Stomach Pain

Rest and relax. Eat and drink slowly or try to have smaller and frequent meals. Keep a heat pad on your stomach. Do not self-manage on your own and consult your doctor if the symptom did not improve on its own.

Tiredness

Drink plenty of fluid and eat balanced diet and frequent meals. Do regular minimal exercise and follow regular sleep schedule.  

Warning & Precautions

Pregnancy

Contraindicated

Prolomet AM 50mg is not recommended for use in pregnant women.  

Breastfeeding

Contraindicated

Prolomet AM 50mg is not recommended for use in breast-feeding women.  

Driving and Using Machines

Use with Caution

Do not drive or handle any machines if you experience tiredness or dizziness while taking Prolomet AM 50mg.

Alcohol

Consult your doctor

Avoid consumption of alcohol during management with Prolomet AM 50mg as it may increase the blood pressure lowering effect of this medicine.

Kidney

Contraindicated

Prolomet AM 50mg is not recommended for use in patients with kidney disease or failure.  

Liver

Consult your doctor

Prolomet AM 50mg is not recommended for use in patients with liver disease. It should be used with caution in patients with liver cirrhosis.

Allergy

Contraindicated

Do not take Prolomet AM 50mg if you are allergic (hypersensitive) to Amlodipine or Metoprolol or any other ingredients of this medicine.

Lungs

Contraindicated

Prolomet AM 50mg is not recommended for use in patients with breathing difficulties or asthma including COPD (chronic obstructive pulmonary disease causing cough, wheezing or breathlessness, phlegm or increase in chest infections).  

Heart Disease

Consult your doctor

Prolomet AM 50mg is not recommended for use in patients with heart conduction or rhythm problems, severe or uncontrolled heart failure, shock caused by heart problems, heart attack, prinzmetal’s angina (suffer from a tight, painful feeling in the chest in periods of rest). It should be used with caution in patients with controlled heart failure and slow heart rate.

Use In Pediatrics

Contraindicated

Prolomet AM 50mg is not recommended for use in children and adolescents (aged less than 18 years).

Use In Geriatrics

Use with Caution

Prolomet AM 50mg should be used with caution in elderly patients (aged 65 years or above), usually the management will be initiated with a lower dosage by your doctor.

Other Warnings for PROLOMET AM 50MG TABLET

Before taking Prolomet AM 50mg, inform your doctor if you have:

• diabetes mellitus
• blood vessel disorder
• psoriasis (severe skin rashes)
• myasthenia gravis
• dry eyes
• hypertensive crisis (severe increase in blood pressure)

Who should not take [GBNKEYWORD

Prolomet AM 50mg is not recommended for use if you have:

• blocked blood vessels including blood circulation problems
• unmanaged phaeochromocytoma
• metabolic acidosis
• low blood pressure
• diabetes associated with frequent episodes of low blood sugar (hypoglycaemia)

Diet and Lifestyle Advice

Diet and Exercise Recommendations

     1. Regular Exercise:

• Engage in consistent physical activity, such as brisk walking, cycling, or moderate exercise, to help control blood pressure and improve cardiovascular health
• Exercise increases your tolerance and helps keep blood pressure stable during activity while on Prolomet AM 50mg Tablet
• Aim for at least 30 minutes of moderate exercise most days of the week, as advised by your doctor

1. Healthy, Balanced Diet:

• Prioritize a diet low in saturated fats and salt to support blood pressure control
• Increase intake of fresh fruits, vegetables, whole grains, and lean proteins
• Reducing salt is especially important, as excess salt can elevate blood pressure further

1. Weight Management:

• Achieving or maintaining a healthy weight enhances medication effectiveness and cardiovascular function

Foods and Activities to Avoid

Foods to Avoid:

• Grapefruit and grapefruit juice: These can enhance the blood pressure-lowering effects of the medicine and increase the risk of side effects. Avoid altogether while on Prolomet AM 50mg Tablet.
• High-salt foods: Minimize processed, packaged, or restaurant foods high in salt, such as chips, pickles, and canned soups.
• Potassium-rich foods and supplements: There is a risk of raised potassium levels with this medication. Unless specifically advised by your doctor, moderate your intake of potassium-rich foods (e.g., bananas, oranges) and avoid potassium supplements.

Activities to Avoid:

• Driving or operating heavy machinery: Until you know how the medicine affects you, avoid tasks requiring full alertness, as dizziness or fatigue may occur, especially when starting therapy.
• Strenuous physical activity: Begin new exercise routines gradually and seek your doctor’s advice, particularly if you experience symptoms such as dizziness, fainting, or excessive fatigue while being active

Drug - Drug interaction

Risk of interactions: Prolomet AM 50mg Tablet can interact with several other medicines, including:

• Other blood pressure medications
• Medicines for irregular heartbeats
• MAO inhibitors
• Some diabetes medications (can affect blood sugar recognition and control)
• Always inform your doctor about all prescription drugs, over-the-counter products, supplements, and herbal medicines you are taking before starting Prolomet AM 50mg
• Abruptly stopping Prolomet AM 50mg (especially with certain heart medicines) is not advised unless supervised by a healthcare provider

Drug - Food interaction

Avoid grapefruit/grapefruit juice: Grapefruit and its juice can interact with the components of Prolomet AM 50mg (particularly amlodipine), potentially increasing drug levels in your blood and the risk of side effects.

Synopsis

More Information

Management Tips:

How to handle mild side effects at home (hydration, rest, dietary adjustments)?

1. Hydration

• Drink plenty of water, especially if experiencing fatigue, dizziness, or muscle cramps.
• Staying hydrated can help combat tiredness and reduce the risk of low blood pressure.

2. Rest

• If you feel tired, dizzy, or have a headache, take a break and rest in a comfortable position.
• Avoid sudden movements like stand up slowly from sitting or lying positions to prevent orthostatic hypotension (sudden drop in blood pressure when standing).

3. Dietary Adjustments

• Nausea/Vomiting: Stick to simple, light meals; avoid oily, rich, fried, or spicy foods. Do not lie down or sleep immediately after eating.
• Headache: Drink ample water, avoid skipping meals, get adequate rest, and use a pain-relief balm if necessary.
• Tiredness: Eat regular, balanced meals, keep a consistent sleep schedule, and include minimal but regular exercise appropriate to your condition.
• Diarrhea: Drink water or fruit juices to stay hydrated. Avoid self-medicating for diarrhea and consult your doctor if it persists.
• Stomach Pain: Eat small and frequent meals, avoid heavy or spicy foods, and rest as needed

What symptoms require immediate medical attention? (e.g., severe dizziness, fainting, irregular heart beat)

Precautions and Safety: Who should avoid the Prolomet AM 50mg Tablet

FAQs About PROLOMET AM 50MG TABLET

References

1. KD Tripathi. Antihypertensive drugs. Essentials of Medical Pharmacology. Seventh edition. May 2013. Page – 561.

2. N. Srinivasa Rao, Abraham Oomman, P. L. Bindumathi, Vikram Sharma, Satish Rao, Latha Subramanya Moodahadu, Ashis Patnaik and B. R. Naveen Kumar. Efficacy and tolerability of fixed dose combination of metoprolol and amlodipine in Indian patients with essential hypertension. Jul-Sep. 2013. [Accessed on 11th July 2025] 

3. Padmini Devi, Denis Xavier, Alben Sigamani, Sudhanshu Pandey, Tinku Thomas, Sreenivas Murthy, Kamal Sharma, Balraj Bosco, Ketan Mehta, Sindhu Joshi, Rajeev Gupta, Girija Singh, Jagadish Hiremath, Chadha Ds, Ashokan Nambiar, Prem Pais. Effect of fixed dose combinations of metoprolol and amlodipine in essential hypertension: MARS--a randomized controlled trial. NIH National Library of Medicine, National center for biotechnology information. Pubmed.gov. December 2011. [Accessed on 11th July 2025] 

4. Torrent pharmaceuticals Ltd. Tolol AM 50 (Metoprolol Succinate Prolonged release and Amlodipine Tablets). [Revised in May 2020] [Accessed on 11th July 2025] 

Useful Diagnostic Tests

• Kidney Function Test

Author Details

Written By Dr. Karthikeyan Rajagopal - M.Pharm (Pharmacology)

Reviewed For Accuracy By Dr. Thamada Manikanta Praveen - MBBS, MD (General Medicine)

Last updated on 16 Jul 2025 | 02:52 PM(IST)