Placida Tablet 10'S

INTRODUCTION ABOUT PLACIDA TABLET

PLACIDA TABLET contains Flupenthixol and Melitracen, which belong to the group of medicines called antipsychotics and tricyclic antidepressants. It is used in the management of anxiety, depression, and asthenia. It is also used to manage neurasthenia, psychogenic depression, masked depression, menopausal depression, dysphoria, depression in alcoholics and drug addicts, and psychosomatic affections that are accompanied by anxiety and apathy with depressive neuroses.

Anxiety is a feeling of fear, dread, and uneasiness that is generally characterized by symptoms such as a fast heart rate, rapid breathing, sweating, and tiredness. Depression is a mood disorder that causes a persistent feeling of sadness and loss of interest, leading to emotional and physical problems accompanied by symptoms such as changes in sleep, appetite, and daily behaviour.

Avoid taking PLACIDA TABLET if you are a manic patient and/or have heart diseases such as circulatory collapse, a depressed level of consciousness, blood disorders, or hereditary problems of galactose (sugar) intolerance. Before taking PLACIDA TABLET, inform your doctor if you have convulsions, organic brain syndrome, a history of suicide-related events, diabetes, planned surgeries, or reduced liver or kidney function.

PLACIDA TABLET is not recommended for use by pregnant women unless recommended by your doctor. Because it can pass through breast milk, it should be used with caution in breastfeeding women. PLACIDA TABLET is not recommended for use in children and adolescents (below 18 years of age). The most common symptoms of taking PLACIDA TABLET are sleeplessness, restlessness, agitation, dizziness, tremors (involuntary movements of muscles), dry mouth, and constipation. Consult your doctor if any of the symptoms are worse.

USES OF PLACIDA TABLET

• Manages anxiety, depression, and asthenia (weakness) and also includes neurasthenia, psychogenic depression, masked depression, menopausal depression, dysphoria and depression in alcoholics and drug addicts
• Manages psychosomatic affections accompanied by anxiety and apathy with depressive neuroses

HOW PLACIDA TABLET WORKS

PLACIDA TABLET effectively manages anxiety, depression, and asthenia. Flupenthixol reduces depression and anxiety by blocking the release of dopamine. Melitracen reduces depression by increasing the level of chemical messengers in the brain that result in the regulation of mood and improvement from depression.

DIRECTIONS FOR USE

Take PLACIDA TABLET as advised by your doctor. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending on your age, disease condition, and body weight.

SIDE EFFECTS OF PLACIDA TABLET

HOW TO MANAGE SIDE EFFECTS

Constipation

Consume high-fiber foods like fruits and vegetables, cereals, and plenty of water. Maintain regular exercise (going for a daily walk or run), and if this does not help, consult your doctor immediately.

Dizziness Or Drowsiness

Try to rest and get enough sleep. Try to avoid driving or operating any tools or machines while you feel dizzy. Avoid the consumption of alcohol, as it can aggravate dizziness. Consult your doctor if the symptom does not improve.

Dry Mouth

Try to drink plenty of water to keep yourself hydrated, and use lip balm if your lips are dry. Brush your teeth twice a day and use mouthwash. Consult and inform your doctor if the symptom gets worse.

WARNING & PRECAUTIONS

PREGNANCY

Monitoring required

PLACIDA TABLET is generally not recommended for use by pregnant women unless recommended by your doctor. Consult your doctor before taking it.

BREASTFEEDING

Use with Caution

PLACIDA TABLET should be used with caution by breastfeeding mothers as it can pass through the breast milk. Consult your doctor before taking it.

DRIVING AND USING MACHINES

Use with Caution

Do not drive or operate any machines if you feel a loss of attention or concentration after taking PLACIDA TABLET.

ALCOHOL

Consult your doctor

Avoid consumption of alcohol while taking PLACIDA TABLET as it may worsen your condition.

KIDNEY

Use with Caution

PLACIDA TABLET should be used with caution in patients having reduced kidney function. Consult your doctor before taking it.

LIVER

Use with Caution

PLACIDA TABLET should be used with caution in patients with liver diseases such as advanced hepatic impairment and reduced liver function. Consult your doctor before taking it.

ALLERGY

Contraindicated

Do not take PLACIDA TABLET if you are allergic to Flupenthixol and/or Melitracen.

HEART DISEASE

Contraindicated

PLACIDA TABLET is not recommended for use in patients having heart diseases such as recent myocardial infarction, any degree of heart block, disorders of cardiac rhythm and coronary artery insufficiency. Consult your doctor before taking it.

USE IN PEDIATRICS

Contraindicated

PLACIDA TABLET is not recommended for use in children and adolescents below 18 years of age. Consult your doctor before taking it.

USE IN GERIATRICS

Use with Caution

PLACIDA TABLET should be used with caution in elderly patients (aged above 75 years of age). Consult your doctor before taking it.

INTERACTIONS

A. Drug-Drug Interactions:

Inform your physician if you are taking any of the following drugs before taking PLACIDA TABLET:

• Medicines used to manage depression, such as MAO inhibitors (Ex. moclobemide and selegiline) and SSRIs (Ex. citalopram)
• Medicines used to manage nasal congestion (Ex. phenylephrine, phenylpropanolamine)
• Medicines used in general anaesthetics (Ex. adrenaline, ephedrine, isoprenaline, and noradrenaline)
• Medicines used in antihypertensive therapies (Ex. guanethidine, betanidine, reserpine, and clonidine)
• Anticholinergic agents (Ex. atropine)
• Medicines used to manage mental illness (Ex. lithium) and Parkinson’s disease (Ex. levodopa)

Overdosage:

If you or someone else has accidentally taken too much PLACIDA TABLET, contact your doctor right away or go to a nearby hospital. The symptoms of overdosage are excessive sleepiness, irritability, agitation, hallucinations, dilated pupils, fast heartbeat, irregular heartbeat, cardiac failure, low blood pressure, cardiogenic shock, urinary retention, mucosal dryness, intestinal hypomotility (infrequent bowel movements), convulsions, fever, a depressed level of consciousness, a coma, respiratory depression, metabolic acidosis (serious electrolyte imbalance), and a low potassium level.

SYNOPSIS

MORE INFORMATION

• Keep PLACIDA TABLET out of reach of children
• Store at room temperature

FAQs ABOUT PLACIDA TABLET

Q: What is the PLACIDA TABLET and why is it given?

A: PLACIDA TABLET contains Flupenthixol and Melitracen, which belong to the group of medicines called antipsychotics and tricyclic antidepressants and are used to manage anxiety, depression, and asthenia.

Q: Can PLACIDA TABLET cause alterations in concentration?

A: Yes. PLACIDA TABLET can cause difficulty paying attention or concentrating. Therefore, it is advised not to drive or operate any machinery or tools until you feel normal again after taking PLACIDA TABLET.

Q: Is PLACIDA TABLET safe for pregnant and breastfeeding women?

A: PLACIDA TABLET is not recommended for use in pregnant women unless the expected benefit outweighs the risk to the fetus. It should be used with caution by breastfeeding mothers, as it can pass through the breast milk. Consult your doctor before taking it.

Q: Can PLACIDA TABLET be given to children?

A: No, PLACIDA TABLET is not recommended for use in children and adolescents (below 18 years of age). If PLACIDA TABLET is accidentally ingested by a child or adolescent, go to the hospital immediately and consult the doctor for further management.

Q: What important things shall I take care of while taking PLACIDA TABLET?

A: PLACIDA TABLET acts on the central nervous system. Hence, if you notice any unusual changes in behaviour or suicidal behaviour or thoughts, stop taking PLACIDA TABLET and contact your doctor immediately.

Q: Can PLACIDA TABLET be taken with other medications?

A: Before taking PLACIDA TABLET, inform your doctor about all other medications, supplements, or herbal products you are currently taking. Certain medications may interact with PLACIDA TABLET, potentially increasing the risk of side effects or reducing its effectiveness.

Q: How long does it take for PLACIDA TABLET to start working?

A: It may take several weeks for PLACIDA TABLET to start working effectively. It's essential to continue taking the medication as prescribed by your doctor, even if you do not notice immediate improvement in your symptoms.

Q: Can PLACIDA TABLET be addictive?

A: PLACIDA TABLET is not typically considered addictive when used as prescribed for the management of depression and anxiety disorders. However, sudden discontinuation of the medication may lead to withdrawal symptoms, so it's essential to taper off the dosage under medical supervision if discontinuation is necessary.

Q: Are there any dietary restrictions or considerations while taking PLACIDA TABLET?

A: While there are no specific dietary restrictions associated with PLACIDA TABLET it's essential to maintain a balanced diet and avoid excessive alcohol consumption, as alcohol can exacerbate certain side effects of the medication.

Q: How does PLACIDA TABLET work?

A: PLACIDA TABLET effectively manages anxiety, depression, and asthenia. Flupenthixol reduces depression and anxiety by blocking the release of dopamine. Melitracen reduces depression by increasing the level of chemical messengers in the brain that result in mood regulation and improvement from depression.

Q: What are the side effects of taking PLACIDA TABLET?

A: The most common symptoms of taking PLACIDA TABLET are sleeplessness, restlessness, agitation, dizziness, tremors (involuntary movements of muscles), dry mouth, constipation, and weakness (accommodation disorder). Consult your doctor if any of the symptoms are worse.

Q: What precautions must be taken while using PLACIDA TABLET?

A: Before taking PLACIDA TABLET, inform your doctor if you have liver, kidney disease, convulsions, organic brain syndrome, urinary retention, signs of hyperthyroidism such as unintentional weight loss, rapid and irregular heartbeat, a history of suicide-related events, diabetes, or have planned surgeries.

Q: Who should not take PLACIDA TABLET?

A: Do not take PLACIDA TABLET if you are allergic to Flupenthixol and/or Melitracen or have heart diseases such as recent myocardial infarction, any degree of heart block, disorders of cardiac rhythm and coronary artery insufficiency, circulatory collapse, depressed level of consciousness due to any cause, blood disorders, coma, phaeochromocytoma (neuroendocrine tumour), hereditary problems related to galactose intolerance, total lactase deficiency or glucose-galactose malabsorption, excitability, overactivity, or mania, or dementia-related behavioural disturbance.

Q: How to purchase PLACIDA TABLET online?

A: If you wish to buy PLACIDA TABLET on Netmeds, you need a prescription from a registered medical practitioner. Netmeds has made buying online medicines more easy for consumers and is one of India's leading online pharmacies.

REFERENCES

1. KD. Tripathi. Drugs Used in Mental Illness: Antipsychotic and Antimanic Drugs. Seventh 7th edition. 2013. Page – 441.

2. Flupenthixol. NIH National Library of Medicine, National center for biotechnology information. Pubchem. [Revised in July 2022] [Accessed on 22nd March 2024] https://pubchem.ncbi.nlm.nih.gov/compound/cis-Flupentixol#section=MeSH-Pharmacological-Classification

3. Melitracen. NIH. National Library of Medicine, National center for biotechnology information. Pubchem. [Revised in July 2022] [Accessed on 22nd March 2024] https://pubchem.ncbi.nlm.nih.gov/compound/Melitracen#section=Pharmacology-and-Biochemistry

4. Lynn Gers, Mirko Petrovic, Stany Perkisas, and Maurits Vandewoude. NIH National Library of Medicine, National center for biotechnology information. PMC PubMed Central. [Revised in May 2018] [Accessed on 22nd March 2024] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6199683/

5. C.G. Papaloisou Ltd. Deanxit. [Revised in Aug 2020] [Accessed on 22nd March 2024] https://www.papaloizou.com/PublicDocsPDF/SPCs/Deanxit_SPC.pdf

USEFUL DIAGNOSTIC TESTS

• Complete Blood Count (CBC)/ Hemogram
• Thyroid Stimulating Hormone (TSH)
• Free Thyroxine (Ft4)
• Free Triiodothyronine (Ft3)
• Urine Routine & Microscopy
• Random Blood Sugar (Rbs)
• Healthy Midlife Checkup
• Men Health Checkup - Advanced
• Complete Women Checkup
• Senior Citizen Checkup - Female
• Senior Citizen Checkup – Male
• Women Health Checkup – Essential
• Full Body Checkup - Gold
• Elderly Checkup - Female
• Elderly Checkup - Male
• Full Body Checkup – Silver

AUTHOR DETAILS

Written By Dr. N. Sai Swaroop - Pharm.D

Last updated on 04 Apr 2024 | 09:48 AM(IST)