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Glaxosmithkline Pharmaceuticals Ltd

Phexin Paediatric Drops 10ml

Bacterial Infections
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    Introduction About PHEXIN PAEDIATRIC DROPS

    PHEXIN PAEDIATRIC DROPS contains Cephalexin which belongs to the group of medicines called Antibiotics. It is used to manage bacterial infections of the breathing tract (Ex. tonsillitis, pharyngitis, and bronchitis), middle ear (otitis media), skin and soft tissue, bone and joints, reproductive organs, and urinary tract (cystitis, prostatitis).

    PHEXIN PAEDIATRIC DROPS can also be used to manage dental infections. Bacterial infections are usually characterized by fever, extreme tiredness, swollen lymph nodes in the neck, armpits, groin or elsewhere, headache, nausea or vomiting.

    Before taking PHEXIN PAEDIATRIC DROPS, inform your doctor if you have any kidney problems or if you are due for a blood or urine test as PHEXIN PAEDIATRIC DROPS may interfere with these tests.

    PHEXIN PAEDIATRIC DROPS should be used with caution in pregnant and breastfeeding women so, contact your doctor before taking it. PHEXIN PAEDIATRIC DROPS can be used in children, however, your doctor will decide the exact dose and duration of the medicine for your child.

    The most common side effect of taking PHEXIN PAEDIATRIC DROPS is diarrhea. Contact your doctor if any of the symptoms are getting worse.

    Uses Of PHEXIN PAEDIATRIC DROPS

    Manages bacterial infections that occur in:

    • respiratory tract (Ex. tonsillitis, pharyngitis, and bronchitis)
    • middle ear
    • skin and soft tissue
    • bone and joint
    • reproductive and urinary tract (Ex. cystitis, prostatitis)
    • dental parts

    How PHEXIN PAEDIATRIC DROPS Works

    PHEXIN PAEDIATRIC DROPS is a broad-spectrum antibiotic that shows bactericidal action (kills the bacteria) by inhibiting the formation of bacterial cell wall.

    How to use PHEXIN PAEDIATRIC DROPS

    Take PHEXIN PAEDIATRIC DROPS as advised by your physician. Add advised amount of water slowly, then replace the cap back. Shake it well, discard the cap and fit the dropper. Dose and duration of PHEXIN PAEDIATRIC DROPS will be decided by your physician depending upon your age, body weight and disease condition.

    Side Effects Of PHEXIN PAEDIATRIC DROPS

    Common

    • diarrhoea

    Rare

    • transient hepatitis, cholestatic jaundice (yellowish discolouration of skin and eyes)

    Stop taking PHEXIN PAEDIATRIC DROPS and contact your doctor immediately if you experience any of the following side effects:

    • allergic reaction
    • acute generalized exanthematous pustulosis (red scaly widespread rash with bumps under the skin and blisters along with fever at the beginning of the management)

    How To Manage Side Effects

    Diarrhea:

    Have plenty of fluids like water or fruit juice to maintain hydration. If symptom persists, contact your doctor.

    Warning & Precautions

    Pregnancy

    PHEXIN PAEDIATRIC DROPS should be used with caution in pregnant women. Contact your doctor before taking it.

    Breastfeeding

    PHEXIN PAEDIATRIC DROPS should be used with caution in breastfeeding women as it is excreted in human milk. Contact your doctor before taking it.

    Driving and Using Machines

    PHEXIN PAEDIATRIC DROPS does not affect your ability to drive or operate machines.

    Kidney

    PHEXIN PAEDIATRIC DROPS should be used with caution in patients with markedly impaired kidney function. Contact your doctor before taking it.

    Liver

    There is no relevant information about the use of PHEXIN PAEDIATRIC DROPS in liver patients. Consult your doctor before taking it.

    Allergy

    Do not take PHEXIN PAEDIATRIC DROPS if you are allergic to cephalexin, other cephalosporins, or any of the other ingredients of this medicine.

    Others

    Before taking PHEXIN PAEDIATRIC DROPS tell your doctor if you:

    • are due for a blood or urine test
    • have penicillin sensitivity

    Use in Paediatrics:

    PHEXIN PAEDIATRIC DROPS can be used for children, however, your doctor will decide the exact dose and duration of the medicine. Hence, contact your child’s doctor for advice.

    Use in Geriatrics:

    PHEXIN PAEDIATRIC DROPS should be used with caution in elderly patients, as they are more likely to have reduced kidney function. Consult your doctor before taking it

    Interactions

    A. Drug-Drug Interactions:

    Before taking PHEXIN PAEDIATRIC DROPS, inform your doctor if you are taking any of the following medicines:

    • other medicines used for bacterial infections (Ex. gentamicin, tobramycin, cefuroxime, colistin)
    • water tablets used to manage water retention (Ex. furosemide, ethacrynic acid)
    • probenecid (used to manage gout)
    • metformin (used to manage diabetes)
    • polymyxin (used to manage fungal infections)
    • medicines used to manage leukaemia (Ex. daunorubicin, cytarabine)
    • medicines used for blood thinning (Ex. rivaroxaban, dabigatran)
    • live typhoid vaccine
    • medicines used to manage pregnancy (Ex. estradiol, progestin)

    Overdosage:

    If you or anyone else accidentally take too much of PHEXIN PAEDIATRIC DROPS, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose include nausea, vomiting, distress in upper abdomen, diarrhoea and blood in urine.

    Synopsis

    Drug :   Cephalexin
    Pharmacological Category :   Cephalosporin antibiotic
    Therapeutic Indication :   Bacterial infections
    Dosage Forms :   Tablet, Capsule, Dispersible tablet, Drops, Dry syrup, Syrup, Oral suspension, Premix

    More Information

    • Keep PHEXIN PAEDIATRIC DROPS out of sight and reach of children
    • Store PHEXIN PAEDIATRIC DROPS below 30°C

    FAQs About PHEXIN PAEDIATRIC DROPS

    Can PHEXIN PAEDIATRIC DROPS be used for cough and cold?

    Antibiotic medicines such as PHEXIN PAEDIATRIC DROPS will not work for colds, flu, or other viral infections. Using antibiotics when they are not required increases your risk of getting an infection later that resist antibiotic management. Consult your doctor for further queries.

    Can PHEXIN PAEDIATRIC DROPS be taken in pregnancy?

    PHEXIN PAEDIATRIC DROPS should be used with caution in pregnancy. If you are pregnant, think you may be pregnant or are planning to have a baby, consult your doctor before taking it.

    Can I take PHEXIN PAEDIATRIC DROPS if I am diabetic?

    Ask your doctor if you can take PHEXIN PAEDIATRIC DROPS while having diabetes but, inform your doctor if you are taking metformin (a medicine used to manage diabetes) as this can cause a potential drug interaction.

    What if I forget to take a dose of PHEXIN PAEDIATRIC DROPS?

    If you forget to take a dose of PHEXIN PAEDIATRIC DROPS, take it as soon as you remember. However, skip that dose if it's almost time for the next one. Do not take PHEXIN PAEDIATRIC DROPS two times to make up for the missed dose.

    Can PHEXIN PAEDIATRIC DROPS cause diarrhea?

    Yes. Diarrhea is a common problem caused by antibiotics like PHEXIN PAEDIATRIC DROPS and usually resolves when the medicine is discontinued. Sometimes, frequent watery or bloody diarrhea may occur and may be a sign of a more serious bowel infection. In case you experience anything like that, contact your doctor.

    Can I stop taking PHEXIN PAEDIATRIC DROPS?

    Continue taking PHEXIN PAEDIATRIC DROPS until your doctor tells you to stop, unless you experience any unwanted effects, worsening of your condition or any new symptoms. Contact your doctor in such case.

    References

    1. Dan L. Longo, Anthony S. Fauci, Dennis L. Kasper, Stephen L. Hauser, J. Larry Jameson, Joseph Loscalzo. Streptococcal/Enterococcal Infections. Harrison’s Manual of Medicine. 18th edition. Page- 595.

    2. K.D. Tripathi. Antimicrobial Drugs. Essentials of Medical Pharmacology. 8th edition. 2019. Page 776.

    3. Derrick CW Jr, Reilly K. The role of cephalexin in the treatment of skin and soft-tissue infections. NIH National Library of Medicine, National center for biotechnology information. Pubmed.gov. 1983. [Accessed on 29th October 2022] https://pubmed.ncbi.nlm.nih.gov/6364089/

    4. Disney FA. Cephalexin in the treatment of upper respiratory tract infections. NIH National Library of Medicine, National center for biotechnology information. Pubmed.gov. 1983. [Accessed on 29th October 2022] https://pubmed.ncbi.nlm.nih.gov/6364087/

    5. Pragma Pharmaceuticals, LLC. U.S. Food and Drugs Administration. [Revised in December 2018] [Accessed on 29th October 2022] https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/050406s013lbl.pdf

    6. Glaxo SmithKline Pharmaceuticals Limited. Phexin BD (Cephalexin). [Revised in June 2020] [Accessed on 29th October 2022] https://india-pharma.gsk.com/media/6398/phexin-oral-formulations.pdf

    7. GlaxoSmithKline Pharmaceuticals. Ceporex Oral Drops (Cephalexin). [Revised in September 2016] [Accessed on 29th Oct 2022] https://gskpro.com/content/dam/global/hcpportal/en_PH/Pdf/Homepage/elsevier-and-pharmacist/Ceporex.pdf

    Useful Diagnostic Tests

    • Complete Blood Count (CBC)

    Author Details

    Written By Dr. Jeenal Rajani - Pharm.D.
    Reviewed For Accuracy By Dr. Salem Gill - MBBS
    Last updated on 03 Nov 2022 | 02:03 PM(IST)
    Lab updated