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Introduction About PHENSEDYL CR SYRUP
PHENSEDYL CR SYRUP is a combination of Ambroxol, Guaiphenesin, Levocetirizine, Menthol which belongs to the group of medicines called Mucolytics, Expectorants, Antihistamines and Antitussives respectively. It is used to manage allergic cold, bronchitis, nasopharyngitis (common cold), bronchial asthma, allergic cough, and maxillary sinusitis. Bronchitis is the inflammation of lungs with symptoms of coughing up thickened mucus (phlegm) and difficulty to breath.
Bronchial asthma has the symptoms of wheezing, chest tightness, excessive coughing, difficulty to breath. Maxillary sinusitis is an inflammation to sinus cavity by bacteria, virus, or fungi with symptoms of thick nasal discharge, nasal block, pain, and pressure around eyes. PHENSEDYL CR SYRUP is not recommended for use in patients who are pregnant, breast-feeding women, with severe kidney diseases and in children and adolescents below 12 years of age.
PHENSEDYL CR SYRUP should be used with caution if you are having diabetes or following sodium-controlled diet. The most common side effects of PHENSEDYL CR SYRUP are dry mouth, tiredness, sedation, constipation, nausea, vomiting, stomach pain, urinary discomfort. Contact your doctor if any of the above side effects worsen or persists for a longer duration.
Uses Of PHENSEDYL CR SYRUP
It is used to manage:
- allergic cold
- nasopharyngitis
- bronchitis
- bronchial asthma
- allergic productive cough
- maxillary sinusitis
How PHENSEDYL CR SYRUP Works
PHENSEDYL CR SYRUP is a combination of Ambroxol, Guaiphenesin, Levocetirizine and Menthol. Levocetirizine blocks histamine receptors and manage the release of allergy causing chemicals. Ambroxol is a mucolytic agent, controls the overproduction of mucus and reduces the viscosity of the phlegm, making it easier to cough up. Guaiphenesin promotes mucus clearance, facilitates coughing up and spit out the sputum. Menthol is added into the combination because of its cooling effect on the throat. Thus PHENSEDYL CR SYRUP eliminates phlegm and relieves the symptoms of allergy, cold and asthma.
How to use PHENSEDYL CR SYRUP
Take PHENSEDYL CR SYRUP as advised by your physician. Shake well before use. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.
Side Effects Of PHENSEDYL CR SYRUP
Common
- taste changes
- excessive sleep
- numbness in throat, mouth, tongue
- nausea
- tiredness
- common cold
- fever
- nose bleeds
Uncommon
- dry mouth
- diarrhoea
- digestive problems
- vomiting
- stomach pain
Rare
- hypersensitivity reactions
- running nose
- rashes, hives
Stop taking PHENSEDYL CR SYRUP and contact your doctor immediately if you experience any of the following side effects:
- allergic contact dermatitis
- decrease in blood pressure, difficulty in breathing, wheezing, faster heart rate, confusions, fainting (symptoms of anaphylactic shock)
- painless swelling under skin due to medicines or any other substance (angioneurotic edema)
- lesions on inner membrane of throat, mouth, throat, eyes and genitals
How To Manage Side Effects

Diarrhea
Keep yourself hydrated by drinking plenty of fluids and electrolytes such as ORS. Consult doctor before taking any medication.

Headache
Drink plenty of fluids and stay hydrated. Try to be tension free and relaxed. Take adequate sleep and rest. Avoid consumption of alcohol. Apply pain balm if required. Consult your doctor if it is getting worsened.

Nausea And Vomiting
Avoid eating fried and greasy food. Take simple, light, small meals at frequent intervals. Keep yourself hydrated by drinking lots of fluids.
Warning & Precautions

Pregnancy
ContraindicatedPHENSEDYL CR SYRUP is not recommended for use if you are pregnant. Consult your doctor before taking.

Breastfeeding
ContraindicatedPHENSEDYL CR SYRUP is not recommended for use in breast feeding mothers. Consult your doctor before taking.

Driving and Using Machines
Use with CautionDo not drive or operate machines if you are feeling sleepy, dizzy after taking PHENSEDYL CR SYRUP. Consult your doctor before taking.

Kidney
ContraindicatedPHENSEDYL CR SYRUP is not recommended to use in patients suffering from kidney failure (renal impairment) or in patients who are at the end stage renal disease (severe kidney disease). Consult your doctor before taking PHENSEDYL CR SYRUP.

Liver
Use with CautionPHENSEDYL CR SYRUP should be taken with caution in patients suffering from serious liver diseases. Consult your doctor before taking PHENSEDYL CR SYRUP.

Allergy
ContraindicatedDo not take PHENSEDYL CR SYRUP if you are allergic to Ambroxol, Levocetirizine, Guaiphenesin, Menthol, or any other ingredients of this medicine.

Lungs
Use with CautionPHENSEDYL CR SYRUP should be taken with caution in patients suffering from chronic cough, asthmatic attack and in patients suffering from a bronchial motor activity disorder along with a large production of mucus. Consult your doctor before taking PHENSEDYL CR SYRUP.

Use In Pediatrics
ContraindicatedPHENSEDYL CR SYRUP is not recommended to use in children and adolescents below 12 years of age. Consult your doctor before taking.

Use In Geriatrics
Use with CautionPHENSEDYL CR SYRUP should be used with caution in elderly patients. Consult your doctor before taking.
Others
Before taking PHENSEDYL CR SYRUP inform your doctor if you:
- have sensitivity to any food or medicine
- have diabetes
- are following a sodium-controlled diet
- having blood disorder (porphyria)
- have ulcer in stomach or intestine
Interactions
A. Drug-Drug interactions:
Before taking PHENSEDYL CR SYRUP inform your doctor if you are taking following medicines:
- medicines used to manage infections (Ex. amoxycillin, cefuroxime, doxycycline, erythromycin)
- medicines used to manage cough (Ex. pholcodine, diphenhydramine)
Overdosage:
If you or anyone else accidentally took too much of PHENSEDYL CR SYRUP, consult your doctor immediately. Symptoms of overdose include nausea, vomiting and feeling sick.
Synopsis
Drug | : | Ambroxol, Guaiphenesin, Levocetirizine, Menthol |
Pharmacological Category | : | Mucolytics, Expectorants, Antihistamines |
Therapeutic Indication | : | Manages symptoms of common cold, allergic cold, bronchitis, bronchial asthma |
Dosage Forms | : | Syrup, Expectorant |
More Information
- Keep PHENSEDYL CR SYRUP out of reach of children
- Store PHENSEDYL CR SYRUP at room temperature
FAQs About PHENSEDYL CR SYRUP
Q: What is PHENSEDYL CR SYRUP used for?
A: PHENSEDYL CR SYRUP is for the management of allergic cold, common cold, bronchitis, bronchial asthma, chronic productive cough, and maxillary sinusitis. Consult your doctor before taking PHENSEDYL CR SYRUP.
Q: What are the most common side effects of taking PHENSEDYL CR SYRUP?
A: The most common side effects of PHENSEDYL CR SYRUP are dry mouth, tiredness, sedation, constipation, nausea, vomiting, stomach pain, urinary discomfort, contact your doctor if any of the symptoms worsen.
Q: How PHENSEDYL CR SYRUP works?
A: PHENSEDYL CR SYRUP is a combination of Ambroxol, Guaiphenesin, Levocetirizine and Menthol. Levocetirizine blocks histamine receptors and manage the release of allergy causing chemicals. Ambroxol is a mucolytic agent, controls the overproduction of mucus and reduces the viscosity of the phlegm, making it easier to cough up. Guaiphenesin promotes mucus clearance, facilitates coughing up and spit out the sputum. Menthol is added into the combination because of its cooling effect on the throat. Thus PHENSEDYL CR SYRUP eliminates phlegm and relieves the symptoms of allergy, cold and asthma.
Q: In which all conditions PHENSEDYL CR SYRUP is contraindicated?
A: PHENSEDYL CR SYRUP is not recommended for use in patients who are pregnant, breast feeding, having severe kidney diseases and in children and adolescents below 12 years of age. Consult your doctor before taking.
Q: What happens if someone take too much of PHENSEDYL CR SYRUP?
A: If you or anyone else accidentally took too much of this medicine, consult your doctor immediately. Symptoms of overdose includes nausea, vomiting and feeling sick.
References
1. R.Eccles. Menthol and related cooling compounds. Eccles, R. Menthol, and related cooling compounds. Journal of Pharmacy and Pharmacology 46, no. 8 (1994): 618-630. [Published in August 1994] [Accessed on 9th August 2022] https://onlinelibrary.wiley.com/doi/abs/10.1111/j.2042-7158.1994.tb03871.x
2. Rekkitt Benckiser Health Care. Electronic Medicines Compendium. (emc). [Revised in May 2016] [Accessed on 9th August 2022] https://www.medicines.org.uk/emc/files/pil.8440.pdf
3. Reckitt Benckiser Healthcare. Health Products Regulatory Authority (HPRA). [Accessed on 9th August 2022] http://www.hpra.ie/img/uploaded/swedocuments/33802379-fb3b-42e2-a664-44a2ae2b4657.pdf
4.Rotapharm. Ambroxol [Accessed on 9th August 2022] http://www.rotapharm.co.uk/wp-content/uploads/Bronolac.pdf
5. Centaur. Levocetirizine, Ambroxol, Menthol. [Accessed on 9th August 2022] https://www.centaurpharma.com/downloads/entchestphysician/cold/Sinarest%20LP%20neo%20Syrup.pdf
6. Sandoz d.d. Ambroxol. [Revised in June 2016] [Accessed on 9th August 2022] https://www.ravimiregister.ee/Data/PIL_ENG/PIL_10403_ENG.pdf
7. Ambroxol+ Guaiphenesin + Levocetirizine + Menthol. Invision medical pharma [Accessed on 9th August 2022] http://www.invisionmedi.com/category/intriz-plus-syrup-.htm
Useful Diagnostic Tests
- Chest Xray
- Sputum culture