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Introduction About OVAA SHIELD DS COMBIPACK
OVAA SHIELD DS COMBIPACK contains a combination of Clomiphene, Acetylcysteine and Astaxanthin which belongs to the group of medicines called Ovulatory stimulant, Mucolytic and Antioxidant respectively. It is used to manage infertility (inability to get pregnant) resulting from ovulatory dysfunction (problems with release of an egg), Polycystic ovary syndrome (hormonal disorder causing infrequent or prolonged menstrual periods).
OVAA SHIELD DS COMBIPACK is also used to manage infertility due to Amenorrhea-galactorrhea syndrome (characterized by the over-production of breast milk (galactorrhea), lack of ovulation (anovulation) and the absence of regular menstrual periods (amenorrhea) and Psychogenic amenorrhea (absence of menstruation due to hypothalamic dysfunction or stress related).
OVAA SHIELD DS COMBIPACK is not recommended for use in patients with bronchial asthma, liver disease. Consult your doctor before taking it.
OVAA SHIELD DS COMBIPACK is not recommended for use in pregnant and breastfeeding women. Consult your doctor before taking it.
OVAA SHIELD DS COMBIPACK is not recommended for use in children and adolescents below 18 years of age. If you experience any side effects after taking this medicine, consult your doctor.
Uses Of OVAA SHIELD DS COMBIPACK
To manage infertility resulting from:
- Ovulatory dysfunction
- Polycystic ovary syndrome
- Amenorrhea-galactorrhea syndrome
- Psychogenic amenorrhea
How OVAA SHIELD DS COMBIPACK Works
OVAA SHIELD DS COMBIPACK is a combination of Clomiphene, Acetylcysteine and Astaxanthin which helps to manage female infertility where clomiphene helps in the production and development of healthy eggs in women. This improves fertility in women and increases the chance of a successful pregnancy in women with polycystic ovary syndrome (PCOS) who experience infertility. Astaxanthin is an antioxidant and reduces damage to egg cells, improves egg quality and thus enhances fertility. Acetylcysteine has some beneficial impacts on endometrial thickness and helps to improve the ovulation and pregnancy rates.
How to use OVAA SHIELD DS COMBIPACK
Take OVAA SHIELD DS COMBIPACK as advised by your physician. Swallow the medicine with water. Do not crush or chew the medicine. Your doctor will decide the right dose and duration depending on your age, body weight and disease condition.
Side Effects Of OVAA SHIELD DS COMBIPACK
Rare
Stop taking OVAA SHIELD DS COMBIPACK and contact your doctor immediately if you experience any of the following side effects:
- shock (severe drop in blood pressure, paleness, restlessness, weak pulse, clammy skin, decreased consciousness) due to widening of blood vessels because of severe allergic reactions
- signs of an allergic reaction such as skin rash, itching, swelling of your lips, face, throat or tongue causing swallowing or breathing problems, cold clammy skin, palpitations, dizziness, weakness or fainting
- signs of a stroke such as numbness, weakness or paralysis on one side of your body, slurred speech, sudden blurred vision, confusion or unsteadiness
- over-stimulation of the ovary causing pain in the pelvis, stomach, swelling or feeling bloated, passing less urine, difficulty in breathing or an increase in weight
- blurring of vision or spots or flashes in front of the eyes
- liver problems include yellowish discoloration of eyes or skin (jaundice)
- sudden and severe headaches
- mental illness such as ‘psychosis’
How To Manage Side Effects
Skin rash Or Itching
Avoid hot bath because hot water can irritate your skin further. Do not scratch the affected area. Use sunscreen and wear protective clothing while going outside. Use unscented moisturizers to soothe and hydrate the affected area. Contact your doctor if your rashes worsen.
Warning & Precautions
Pregnancy
ContraindicatedOVAA SHIELD DS COMBIPACK is not recommended for use in pregnant women or women planning to have a baby. Consult your doctor before taking OVAA SHIELD DS COMBIPACK.
Breastfeeding
ContraindicatedOVAA SHIELD DS COMBIPACK is generally not recommended for use in breastfeeding women as it lowers the amount of breast milk produced. Consult your doctor before taking it.
Driving and Using Machines
Use with CautionDo not drive or use machines while taking OVAA SHIELD DS COMBIPACK as it can cause blurred vision.
Liver
ContraindicatedOVAA SHIELD DS COMBIPACK is not recommended for use in patients who have or ever had liver disease. Consult your doctor before taking OVAA SHIELD DS COMBIPACK.
Allergy
ContraindicatedDo not take OVAA SHIELD DS COMBIPACK if you are allergic to Clomiphene, Acetylcysteine, Astaxanthin or any other ingredients of this medicine.
Lungs
ContraindicatedOVAA SHIELD DS COMBIPACK is not recommended for use in patients with bronchial asthma. Consult your doctor before taking it.
Others
OVAA SHIELD DS COMBIPACK is not recommended for use if you have:
- unusual menstrual bleeding with unknown cause
- a type of cancer that is worsened by hormones
Before taking OVAA SHIELD DS COMBIPACK, inform your doctor if you have:
- early menopause or have been told you are infertile
- stopped having periods because you are underweight
- had fits or seizures in the past
- ovarian cysts (except those from polycystic ovary syndrome)
- fibroids in your womb
- a pituitary tumor
- thyroid disease
- adrenal disease
- hypertriglyceridemia (an excess of fats in the blood) or a family history of hypertriglyceridemia
- intolerance to certain sugars
Use in Pediatrics:
OVAA SHIELD DS COMBIPACK is not recommended for use in children and adolescents below 18 years of age. Consult your doctor before taking OVAA SHIELD DS COMBIPACK.
Interactions
A. Drug-Drug interactions:
Before taking OVAA SHIELD DS COMBIPACK, inform your doctor if you are taking any of the following medicine:
- nitroglycerine (used to manage chest pain)
- activated charcoal (used to manage travelers disease)
- cough suppressants (used to suppress cough) Ex. promethazine
- antibiotics (medicines used to manage bacterial infections) Ex. eythromycin
Overdosage:
If you or anyone else accidentally take too much of OVAA SHIELD DS COMBIPACK, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose include over-stimulation of the ovary causing pain in the pelvis, stomach, swelling or feeling bloated, passing less urine, difficulty in breathing or an increase in weight. Other effects include nausea, vomiting and diarrhea.
Synopsis
| Drug | : | Clomiphene, Acetylcysteine and Astaxanthin |
| Pharmacological Category | : | Ovulatory stimulant, Mucolytic and Carotenoids |
| Therapeutic Indication | : | Infertility in women |
| Dosage Forms | : | Combi pack, Kit, Capsule |
More Information
- Keep OVAA SHIELD DS COMBIPACK out of reach of children
- Store OVAA SHIELD DS COMBIPACK below 25°C
FAQs About OVAA SHIELD DS COMBIPACK
Q: How OVAA SHIELD DS COMBIPACK helps to manage Poly cystic ovary syndrome?
A: OVAA SHIELD DS COMBIPACK helps to maintain the normal hormonal balance in the body and improve pregnancy rates in women who have a problem with ovulation (release of an egg) or have a condition called polycystic ovary syndrome (PCOS). Consult your doctor before taking it.
Q: Can I stop taking OVAA SHIELD DS COMBIPACK?
A: Take OVAA SHIELD DS COMBIPACK according to the doctor advice. Keep taking this medicine until your doctor tells you to stop. Otherwise, it may lead to management failure.
Q: Is OVAA SHIELD DS COMBIPACK safe in pregnant women?
A: No. OVAA SHIELD DS COMBIPACK is not recommended for use in pregnant women or women who are planning to have a baby. Consult your doctor before taking OVAA SHIELD DS COMBIPACK.
Q: What if I forget to take OVAA SHIELD DS COMBIPACK?
A: If you forget a dose of OVAA SHIELD DS COMBIPACK, talk to your doctor as you may need to change your management cycle. Do not take a double dose.
Q: Does OVAA SHIELD DS COMBIPACK cause multiple pregnancies?
A: Yes. OVAA SHIELD DS COMBIPACK increases the chance of multiple pregnancy (twins or more) and cause ectopic pregnancy (pregnancies where the baby grows outside of the womb). Consult your doctor before taking it.
References
1. KD Tripathi. Estrogens, Progestins and Contraceptives. Essentials of medical pharmacology. Seventh Edition. 2013. Page –312.
2. Bethesda (MD). Clomiphene. NIH. National Library of Medicine, National Center for Biotechnology Information. PubChem Compound Summary. 2004. [Accessed on 12th September 2022]. https://pubchem.ncbi.nlm.nih.gov/compound/Clomiphene
3. Bethesda (MD). Acetylcysteine. NIH. National Library of Medicine, National Center for Biotechnology Information. PubChem Compound Summary. 2004. [Accessed on 12th September 2022]. https://pubchem.ncbi.nlm.nih.gov/compound/Acetylcysteine
4. Bethesda (MD). Astaxanthin. NIH. National Library of Medicine, National Center for Biotechnology Information. PubChem Compound Summary. 2004. [Accessed on 12th September 2022]. https://pubchem.ncbi.nlm.nih.gov/compound/Astaxanthin
5. Zentiva k.s. Electronic Medicines Compendium (EMC). [Revised in June 2021] [Accessed on 12th September 2022]. https://www.medicines.org.uk/emc/files/pil.961.pdf
6. Elara Pharmaservices Limited. Electronic Medicines Compendium (EMC). [Revised in January 2022] [Accessed on 12th September 2022]. https://www.medicines.org.uk/emc/files/pil.8576.pdf
7. Astaxanthin. General Pharmaceuticals Limited. [Accessed on 12th September 2022]. https://generalpharma.com/pdf/astagen.pdf
8. Thrioshot combi kit (Clomiphene + N-Acetylcysteine + Astaxanthin). LeeWell Pharmaceuticals Pvt. Ltd. [Accessed on 12th September 2022]. https://leewellpharma.com/shop/ols/products/thri-o-shot-ds-combo-kit-acetylcysteine-600mg-astaxanthin-4mg-clomiphene-100mg
9. Satova (Clomiphene + N-Acetylcysteine + Astaxanthin). Saturn Formulations Pvt. Ltd. [Accessed on 12th September 2022]. https://saturnformulations.in/product/clomifene-citrate-n-acetylcysteine-tablets/
10. Feofer-Ova Kit (Clomiphene + N-Acetylcysteine + Astaxanthin). Alna Biotech Pvt. Ltd. [Accessed on 12th September 2022]. https://www.alnabiotech.com/gynaecology-drugs-for-franchise.html
11. Bethesda (MD). Clomiphene. National Institute of Health: National Library of Medicine. Medline Plus. September 2017. [Accessed on 12th September 2022]. https://medlineplus.gov/druginfo/meds/a682704.html
Useful Diagnostic Tests
- Anti-Mullerian Hormone
- FSH (Follicle stimulating Hormone)
- LH (Luteinizing Hormone)
- Progesterone, estradiol
- Thyroid Stimulating Hormone
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