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Introduction About OSEVIR 45MG CAPSULE
OSEVIR 45MG CAPSULE contains oseltamivir, which belongs to the group of medicines called antivirals. It is used in adults, adolescents, children, and infants (including full-term new-born babies) for the management of flu (influenza) and is also used as management management in a global flu pandemic and when the seasonal flu vaccine may not provide sufficient protection.
OSEVIR 45MG CAPSULE can be used when you have flu symptoms, and the flu virus is known to be spreading in your community. It can also be used to manage flu in adults, adolescents, children, and infants above 1 year of age, but only if you have been in contact with someone affected by flu.
OSEVIR 45MG CAPSULE should be taken with caution in patients with long-term respiratory or heart disease or kidney problems. Consult your doctor before taking this medicine.
OSEVIR 45MG CAPSULE should be used by pregnant and breastfeeding women only if it is considered clearly necessary. Consult your doctor before taking the medicine.
OSEVIR 45MG CAPSULE should be used with caution in children from 1 to 12 years of age and in infants younger than 1 year. It is also used with caution in elderly patients (above 65 years of age). Consult your doctor before taking this medicine.
The most common side effects of taking OSEVIR 45MG CAPSULE are headache, nausea, vomiting, stomach ache, headache, and pain. Contact your doctor if any of the symptoms get worse.
Uses Of OSEVIR 45MG CAPSULE
- Manages flu (influenza) symptoms in adults, adolescents, children, and infants (including full-term new-born babies).
- Prevents flu in adults, adolescents, children, and infants above 1 year of age (including full-term new-born babies in a flu pandemic).
How OSEVIR 45MG CAPSULE Works
OSEVIR 45MG CAPSULE manages the spread of the flu virus inside the body by blocking the action of chemicals required for the survival of the virus. This helps to ease or manage the symptoms of the flu virus infection.
How to use OSEVIR 45MG CAPSULE
Take OSEVIR 45MG CAPSULE as advised by your physician. Swallow OSEVIR 45MG CAPSULE with a glass of water and do not crush or chew it. Take it with food to reduce the chance of nausea and vomiting.
Your doctor will decide the correct dose and duration for you depending on your age, body weight, and the severity of the infection.
Side Effects Of OSEVIR 45MG CAPSULE
Common
- nausea, vomiting, stomach ache, bloating
- headache
- bronchitis (lung infection)
- signs of a cold sore virus (painful, fluid-filled skin blisters)
- cough
- dizziness
- fever
- pain, limb pain
- runny nose
- difficulty sleeping
- sore throat
- tiredness
- upper respiratory tract infections (infections in the nose, throat, and sinuses)
- nasal congestion
- conjunctivitis (red eyes and discharge or pain in the eye)
- ear inflammation and other ear disorders
Uncommon
- allergic reactions
- change in consciousness level
- convulsion (fits)
- heart rhythm abnormalities (fluttering feeling in the chest, chest pain, fainting, or dizziness)
- signs of skin reactions (inflamed, red and itchy rash, scaling skin)
- eardrum disorder
- diaper rash in infants
Rare
- disturbances in vision
Stop taking OSEVIR 45MG CAPSULE and consult your doctor immediately if you experience any of the following side effects:
- anaphylactic and anaphylactoid reactions (severe allergic reactions causing face and skin swelling, itchy rashes, low blood pressure, and breathing difficulties)
- signs of liver disorders such as fulminant hepatitis, hepatic function disorder, and jaundice (yellowing of the skin and eyes, change in stool colour, behavioural changes)
- angioneurotic oedema (sudden onset of severe swelling of the skin mainly around the head and neck area, including the eyes and tongue, with breathing difficulties)
- complicated and life-threatening allergic reaction like Stevens-Johnson syndrome and toxic epidermal necrolysis (severe inflammation of the outer and possibly inner skin, initially with fever, sore throat, fatigue, and skin rashes, leading to blisters, peeling, shedding of larger areas of skin, breathing difficulties, and low blood pressure)
- signs of gastrointestinal bleeding (prolonged bleeding from the large bowel or spitting up blood)
- signs of neuropsychiatric disorders (convulsions and delirium with changed consciousness level, behavioural changes such as confusion, delusions, hallucinations, agitation, anxiety, nightmares, and self-injury)
How To Manage Side Effects
Dizziness Or Drowsiness
Try to rest and relax. Get enough sleep. Avoid driving or operating any machines while you are feeling dizzy. Do not drink alcohol, as it can aggravate your dizziness. Contact your doctor if your dizziness does not improve.
Headache
Rest and relax. Drink plenty of fluids, such as water or ORS (Oral Rehydrating Solution), and apply a pain-relieving balm to the head if necessary. Contact your doctor if the headache does not improve.
Nausea And Vomiting
Take OSEVIR 45MG CAPSULE along with or just after meals. Stick to simple meals. Avoid eating oil-rich or spicy foods. If nausea and vomiting do not improve, contact your doctor.
Stomach Pain
Try to rest and relax. Eat and drink slowly or try to have smaller and more frequent meals. Keep a heat pad on your stomach. If the stomach pain persists, contact your doctor.
Warning & Precautions
Pregnancy
Monitoring requiredOSEVIR 45MG CAPSULE should be used in pregnant women only if it is considered clearly necessary. Consult your doctor before taking the medicine.
Breastfeeding
Monitoring requiredOSEVIR 45MG CAPSULE should be used in breastfeeding women only if considered necessary, as it may pass through the breast milk. Consult your doctor before taking this medicine.
Driving and Using Machines
Use with CautionOSEVIR 45MG CAPSULE does not affect your abilities to drive or while operating machines. Consult your doctor before taking this medicine.
Alcohol
Consult your doctorAvoid or limit the consumption of alcohol while taking OSEVIR 45MG CAPSULE because it might make the medicine less effective.
Kidney
Use with CautionOSEVIR 45MG CAPSULE should be taken with caution in patients with kidney problems and may need dose adjustment. Consult your doctor before taking this medicine.
Liver
Monitoring requiredOSEVIR 45MG CAPSULE can be used safely for management in patients with hepatic dysfunction with no dose adjustment. Consult your doctor before taking OSEVIR 45MG CAPSULE.
Allergy
Use with CautionDo not take OSEVIR 45MG CAPSULE if you are allergic to oseltamivir or any of the other ingredients in this medicine.
Lungs
Use with CautionOSEVIR 45MG CAPSULE should be taken with caution in patients with long-term (chronic) respiratory disease. Consult your doctor before taking OSEVIR 45MG CAPSULE.
Heart Disease
Use with CautionOSEVIR 45MG CAPSULE should be taken with caution in patients with long-term (chronic) heart disease. Consult your doctor before taking this medicine.
Use In Pediatrics
Use with CautionOSEVIR 45MG CAPSULE should be used with caution in children from 1 to 12 years of age and infants less than 1 year. There is no information on the use of OSEVIR 45MG CAPSULE in paediatric patients with hepatic disorders. Consult your doctor before taking this medicine.
Use In Geriatrics
Use with CautionOSEVIR 45MG CAPSULE should be used with caution in elderly patients (above 65 years of age). Consult your doctor before taking this medicine.
Others
Before taking OSEVIR 45MG CAPSULE, inform your doctor if:
- are allergic to other medicines
- have a severe medical condition that might require immediate hospitalisation
- have poor immunity
Interactions
A. Drug- Drug interactions:
Before taking OSEVIR 45MG CAPSULE, inform your doctor if you are taking any of the following medicines:
- chlorpropamide (a medicine used in the management of diabetes)
- methotrexate (used to manage rheumatoid arthritis)
- phenylbutazone (used to reduce pain and inflammation)
- probenecid (a medicine used in the management of gout
Overdosage:
If you or anyone else accidentally takes too much of OSEVIR 45MG CAPSULE, consult your doctor immediately or visit the nearby hospital.
Synopsis
| Drug | : | Oseltamivir |
| Pharmacological Category | : | Neuraminidase inhibitors |
| Therapeutic Indication | : | Management and management of influenza (flu) |
| Dosage Forms | : | Capsule, Oral suspension, Syrup |
More Information
- Keep OSEVIR 45MG CAPSULE out of reach of children
- Store below 25°C
FAQs About OSEVIR 45MG CAPSULE
Q: Is OSEVIR 45MG CAPSULE a substitute for the flu vaccine?
A: No, getting the flu vaccine is the best way to protect against the flu virus and control the spread of the flu infection. Though OSEVIR 45MG CAPSULE manages and manages the flu virus from spreading, it will not change the effectiveness of a flu vaccine, and your doctor will advise both for you. However, talk to your doctor for more information.
Q: What should I do if I am not able to swallow OSEVIR 45MG CAPSULE?
A: If you have trouble swallowing OSEVIR 45MG CAPSULE capsules, you can use a liquid medicine. This can be made by pouring all the powder into a bowl and mixing the powder with a small amount of sweetened liquid, such as regular or sugar-free chocolate syrup, to cover up the bitter taste of the medicine. Give the whole contents of the bowl to the patient right away.
Q: What are the most common side effects of OSEVIR 45MG CAPSULE?
A: The most common side effects of OSEVIR 45MG CAPSULE are nausea and vomiting. Usually, they are not severe and happen in the first 2 days of management. Taking OSEVIR 45MG CAPSULE along with food may lessen the chance of getting these side effects. Other side effects include stomach pain, headache, cough and nasal congestion.
Q: What are the other measures to follow along with OSEVIR 45MG CAPSULE?
A: The important measures to be followed along with OSEVIR 45MG CAPSULE in the management of flu infection include avoiding unnecessary close contact between sick people, covering coughs and sneezes and washing hands frequently. Most importantly, the flu vaccine should be taken.
Q: How long should I take OSEVIR 45MG CAPSULE?
A: OSEVIR 45MG CAPSULE should be taken as soon as possible, ideally within two days of the flu symptoms starting. It is important to take the medicine exactly as advised by the doctor. Usually, the course of management is 5 to 10 days, depending on the disease condition. However, consult your doctor before starting the medicine.
References
1. KD. Tripathi. Antiviral drugs. Essentials of medical pharmacology. Seventh edition. 2013. Page – 802.
2. Karen McClellan & Caroline M. Perry. Oseltamivir -A Review of its Use in Influenza. Drugs journal. January 2013. [Accessed on 12th May 2022] https://link.springer.com/article/10.2165/00003495-200161020-00011
3. Nicholson KG, Aoki FY, Osterhaus AD, Trottier S, Carewicz O, Mercier CH, Rode A, Kinnersley N, Ward P. Efficacy and safety of oseltamivir in treatment of acute influenza: a randomised controlled trial. The Lancet. May 2000. [Accessed on 12th May 2022] https://www.thelancet.com/journals/lancet/article/PIIS0140673600022881/fulltext
4. Roche Products Ltd. Electronic Medicines Compendium (EMC). [Revised in January 2022] [Accessed on 12th May 2022] https://www.medicines.org.uk/emc/files/pil.8050.pdf https://www.medicines.org.uk/emc/files/pil.1194.pdf
5. ANTIFLU Capsules/ Suspension (Oseltamivir phosphate). Ciplamed.com. [Revised in April 2020] [Accessed on 12th May 2022] https://www.ciplamed.com/content/antiflu-capsules-suspension
6. Oselet Capsules (Oseltamivir). Ikon remedies. [Accessed on 12th May 2022] https://www.ikonremedies.com/product/oselet-capsules/
Useful Diagnostic Tests
- Complete blood count
- Viral culture
- Rapid antigen testing
- Reverse transcription polymerase chain reaction (RT-PCR)
- Immunofluorescence assays
- Rapid molecular assays
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