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Introduction About ONICID TABLET
ONICID TABLET contains Omeprazole which belongs to the group of medicines called Proton pump inhibitors. It is used in the management of gastro-oesophageal reflux disease (acid contents in the stomach flow back into the tube connecting your mouth and stomach causing heartburn, nausea, vomiting, bitter taste and discomfort in the upper abdomen) in children (above 1 year of age) and adults.
It is used in adults to manage gastric (stomach), duodenal ulcers (upper part of the intestine), ulcers infected with Helicobacter pylori bacteria in addition to antibiotics (including children) and ulcers due to the use of non-steroidal anti-inflammatory drugs (NSAIDs).
Also, it is used in adults to manage Zollinger-Ellison syndrome (increased acid secretion in the stomach due to growth in the pancreas resulting in abdominal pain, diarrhoea, gnawing or discomfort in the upper abdomen, heartburn, nausea and vomiting).
ONICID TABLET is not recommended for use in patients with history of allergic reactions to omeprazole or any other proton pump inhibitors (Ex. pantoprazole, lansoprazole, rabeprazole and esomeprazole).
Before taking ONICID TABLET, tell your doctor if you have any severe liver problems, weight loss, swallowing problems, stomach pain or indigestion, osteoporosis (a condition in which bones become weak and brittle), vitamin B12 deficiency, schedule for a specific blood test (chromogranin A).
ONICID TABLET can be used in pregnant and breastfeeding women only if advised by the doctor. ONICID TABLET should be used with caution in elderly patients (aged above 65 years) due to the increased risk of fractures.
The most common side effects of taking ONICID TABLET are headache, diarrhoea, stomach pain, constipation and flatulence. Consult your doctor if any of the side effects bother you.
Uses Of ONICID TABLET
Used in the management of the following conditions:
- gastro-oesophageal reflux disease (in adults and children)
- gastric (stomach) ulcer, duodenal ulcer
- ulcers infected with Helicobacter pylori bacteria in addition to antibiotics (in adults and children)
- ulcers due to non-steroidal anti-inflammatory drugs (NSAIDs)
- Zollinger-Ellison syndrome
How ONICID TABLET Works
ONICID TABLET effectively lowers the amount of acid produced in the stomach by irreversibly binding to and inhibiting the hydrogen-potassium ATPase pump that resides on the lining of the digestive tract. This kind of action helps to reduce vomiting, and promote healing of damaged stomach tissue in ulcers.
How to use ONICID TABLET
Take ONICID TABLET as advised by your physician. Swallow ONICID TABLET with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration of ONICID TABLET for you depending on your age, body weight and disease condition.
Side Effects Of ONICID TABLET
Common
- headache
- diarrhoea, stomach pain, constipation, flatulence
- nausea, vomiting
- benign polys in the stomach
Uncommon
- swelling of the feet and ankles
- disturbed sleep (insomnia)
- dizziness, tingling or prickling sensation, feeling sleepy
- spinning feeling (vertigo)
- skin rash, lumpy rash (hives) and itchy skin
- generally feeling unwell and lacking energy
- fracture in the hip, wrist or spine
Rare
- feeling agitated, confused or depressed
- taste changes
- eyesight problems such as blurred vision
- suddenly feeling wheezy or short of breath (bronchospasm)
- dry mouth
- inflammation inside of the mouth, sore mouth or ulcers
- hair loss (alopecia)
- skin rash on exposure to sunshine
- severe kidney problems (interstitial nephritis)
- joint pains (arthralgia) or muscle pains (myalgia)
- increased sweating
Stop taking ONICID TABLET and contact your doctor immediately if you experience any of the following side effects:
- signs of a severe allergic reaction (sudden wheezing, swelling of lips, tongue, throat or body, skin rash, fainting, and difficulty in breathing or swallowing)
- signs of toxic epidermal toxic necrolysis or stevens-johnson syndrome (reddening of the skin with peeling or blisters, also severe blisters and bleeding in the lips, eyes, mouth, nose and genitals)
- liver problems (signs include yellowing of skin, dark urine and tiredness)
How To Manage Side Effects
Constipation:
Take fiber-rich foods in your diet such as fresh fruits, vegetables, whole grain cereals and drink plenty of fluids. Exercise more regularly and stay active. Consult your doctor if the symptom does not improve.
Headache:
Rest and relax. Drink plenty of fluids such as water or electrolytes. Apply a pain-relieving balm on the forehead if required. Do not consume too much alcohol. Consult your doctor if the symptom does not improve.
Nausea or vomiting:
Try to take ONICID TABLET with or just after a meal or a snack. Stick to simple meals. Avoid eating oil rich, fried or spicy foods. Consult your doctor if the symptom does not improve.
Diarrhoea:
Drink lot of fluids such as water or fruit juices to keep yourself hydrated. Avoid taking any medicine on your own for managing diarrhea. Consult your doctor if the symptom does not improve.
Stomach pain:
Rest and relax. Eat and drink slowly or try to have smaller and more frequent meals. Keep a heating pad on your stomach. Do not self-manage on your own and consult your doctor if the symptom does not improve.
Warning & Precautions
Pregnancy
ONICID TABLET can be used in pregnant women or women planning for pregnancy only if advised by the doctor. Therefore, consult your doctor for advice before taking ONICID TABLET.
Breastfeeding
ONICID TABLET is recommended for use in breastfeeding women only if advised by the doctor. Therefore, consult your doctor for advice before taking ONICID TABLET.
Driving and Using Machines
Do not drive or operate any machines if you experience dizziness and visual disturbances after taking ONICID TABLET.
Liver
ONICID TABLET should be used with caution in patients with severe liver problems. Consult your doctor for advice before taking ONICID TABLET.
Allergy
Do not take ONICID TABLET if you are allergic to omeprazole or any other proton pump inhibitors (Ex. pantoprazole, lansoprazole, rabeprazole and esomeprazole).
Others
Before taking ONICID TABLET, inform your doctor if you:
- lose weight for no reason and have swallowing problems
- have stomach pain or indigestion
- vomit the food regularly or the vomit contains blood
- pass black stools (blood-stained faeces)
- have osteoporosis (a condition in which bones become weak and brittle)
- have reduced body stores or risk factors for reduced vitamin B12
- are due to have a specific blood test (chromogranin A)
- are intolerant to certain sugars
Use in pediatrics:
ONICID TABLET should be used with caution in children and adolescents (above 1 year of age). Your child’s doctor may adjust the dose depending on the child’s age and body weight. Consult your child’s doctor for advice.
Use in Geriatrics:
ONICID TABLET should be used with caution in elderly patients (aged above 65 years) due to the increased risk of fractures, especially if used in higher doses and over long durations (>1 year). Consult your doctor for advice before taking ONICID TABLET.
Interactions
A. Drug - Drug interactions:
Before taking ONICID TABLET, inform your doctor if you are taking any of the following medicines:
- medicines used in fungal infections (Ex. itraconazole, ketoconazole, posaconazole or voriconazole)
- digoxin (used to manage heart problems)
- diazepam (used to manage anxiety and epilepsy)
- St. John’s wort (used to manage depression)
- medicines used to manage HIV infection (Ex. atazanavir, saquinavir, nelfinavir)
- rifampicin (used to manage tuberculosis)
- phenytoin (used to manage epilepsy)
- tacrolimus (used to manage organ rejection after transplant)
- cilostazol (used to manage intermittent claudication)
- blood thinning medicines (Ex. warfarin, clopidogrel)
- erlotinib, methotrexate (used to manage cancer)
Overdosage:
If you or anyone else accidentally take too much of ONICID TABLET, contact your doctor immediately or go to a hospital straight away. Overdosage symptoms of ONICID TABLET includes nausea or vomiting, feeling dizzy, stomach pain, diarrhoea, headache, lack of interest, feeling depressed and confusion.
Synopsis
| Drug | : | Omeprazole |
| Pharmacological Category | : | Proton Pump Inhibitors |
| Therapeutic Indication | : | Gastro -oesophageal reflux disease, Stomach and Duodenal ulcer, Zollinger-Ellison syndrome |
| Dosage Forms | : | Tablet, Capsule, Injection, Oral suspension, Powder |
More Information
- Keep ONICID TABLET out of reach of children
- Store at room temperature
FAQs About ONICID TABLET
How does ONICID TABLET work?
ONICID TABLET effectively lowers the amount of acid produced in the stomach by irreversibly binding to and inhibiting the hydrogen-potassium ATPase pump that resides on the lining of the digestive tract. This kind of action helps to reduce vomiting and promote the healing of damaged stomach tissue in ulcers.
Does ONICID TABLET cause constipation?
Yes, ONICID TABLET may cause constipation in some individuals. To manage this effect, take fibre-rich foods in your diet such as fresh fruits, vegetables and whole grain cereals and drink plenty of fluids. Exercise more regularly (such as daily walk) and stay active. Consult your doctor if the symptom does not improve.
Can ONICID TABLET be used in elderly patients?
ONICID TABLET should be used with caution in elderly patients (aged above 65 years) due to the increased risk of fractures, especially if used in higher doses and over long durations (>1 year). Consult your doctor for advice before taking ONICID TABLET.
Can I drive or ride a bike after taking ONICID TABLET?
Do not drive or operate any machines if you experience dizziness and visual disturbances after taking ONICID TABLET. Consult your doctor for advice before taking this medicine.
What are the common side effects of ONICID TABLET?
The most common side effects of taking ONICID TABLET are headache, diarrhoea, stomach pain, nausea, vomiting, constipation and flatulence. Consult your doctor if any of the side effects bother you.
References
1. KD. Tripathi. Gastrointestinal Drugs. Essentials of medical pharmacology. Seventh edition. 2013. Page – 706.
2. Forgerini, Marcela, Stephania Mieli, and Patrícia de Carvalho Mastroianni. Safety assessment of omeprazole use: a review. Sao Paulo Medical Journal. December 2018. [Accessed on 28th May 2022] https://doi.org/10.1590/1516-3180.2018.0019220318
3. Higuera-de-la-Tijera, Fatima. Efficacy of omeprazole/sodium bicarbonate treatment in gastroesophageal reflux disease: a systematic review. Medwave. Europe PMC. [Revised in March 2018][Accessed on 28th May 2022] https://europepmc.org/article/med/29547594
4. Mylan Hungary Kft. The Health Products Regulatory Authority (HPRA). [Revised in March 2017] [Accessed on 28th May 2022] https://www.hpra.ie/img/uploaded/swedocuments/Leaflet-2191137-11072017125746-636353746685625000.pdf
5. Pharmachemie B.V. Omeprazole capsules. [Revised in June 2021] [Accessed on 28th May 2022] https://products.tevauk.com/mediafile/id/51245.pdf
Useful Diagnostic Tests
- Liver Function Test
- Electrolyte panel
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