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Introduction About OMNIPAQUE INJECTION
OMNIPAQUE INJECTION is a radio-contrast agent used for diagnostic purposes only. It helps in diagnosing an illness by taking a clear picture of internal body parts which helps your doctor to tell if there is any abnormality in organ shape and size. It can be used for X-rays of urinary system, spine and blood vessels, including blood vessels supplying the heart, salivary gland, stomach and intestines and for scanning uterus, joints, breasts, ovaries, head and entire body (CAT scan).
OMNIPAQUE INJECTION contains a medicine called Iohexol which is a radio contrast agent. It works by absorbing the X-rays due to its iodine content, making certain areas appear white on scans like CT or X-rays. This helps doctors clearly see blood vessels, organs, and tissues for accurate diagnosis.
Make sure to drink plenty of fluids before and after receiving OMNIPAQUE INJECTION, especially if you have diabetes, myeloma, kidney problems, aged above 65 years or have generally poor health conditions.
Before receiving OMNIPAQUE INJECTION inform your doctor if you have liver, kidney or heart problems. You must also inform your doctor if you are pregnant or breastfeeding or having diabetes, epilepsy, thyroid problems, cancers of bone marrow, muscle weakness, brain problems, etc as a precaution.
The most common side effects of receiving OMNIPAQUE INJECTION are feeling hot or flushed, shortness of breath, respiratory problems, headache, nausea, vomiting, diarrhea, dizziness, Inflammation of pancreas and pain around stomach, Increased/abnormal sweating and feeling cold. Consult your doctor if any of these side effect troubles you.
Uses Of OMNIPAQUE INJECTION
- Radio-contrast agent used for diagnostic purposes
- Takes a clear picture of internal body parts
- Diagnosis illness, abnormality in organ shape and size
- Can be used prior to X-rays of urinary system, spine and blood vessels, including blood vessels supplying the heart, salivary gland, stomach and intestines
- Can be used prior to scanning uterus, joints, breasts, ovaries, head and entire body
How OMNIPAQUE INJECTION Works
OMNIPAQUE INJECTION contains Iohexol which is a contrast agent used in medical imaging to help doctors see blood vessels, organs, and other tissues more clearly during scans like CT or X-rays. It works by absorbing X-rays due to its iodine content, making the areas where it is injected appear white on the scan. This contrast helps to differentiate various structures in the body, aiding in accurate diagnosis.
How to use OMNIPAQUE INJECTION
OMNIPAQUE INJECTION will be given to you only by a doctor or a trained medical professional into your veins (as intravenous injection), into the blood vessels (as intraarterial injection), into the spine, inside joints, or other body cavities (like uterus, ovaries) or by mouth. The route of administration depends up on the organ which needs to be examined. Make sure to drink plenty of water or fluids before and after administration of OMNIPAQUE INJECTION.
Side Effects Of OMNIPAQUE INJECTION
Common
- Feeling hot or flushed
- Shortness of breath, respiratory problems (after an intraarterial injection)
- Headache, nausea, vomiting, diarrhea
- Inflammation of pancreas
- Pain around stomach
Uncommon
- Increased/abnormal sweating
- Feeling cold
- Dizziness/Fainting
- Pain and discomfort (after an intraarterial injection)
- Inflammation of the membranes that surround the brain and spinal cord
Rare
- Slow rate
- Fever
- Irregular heartbeats, cough, stopped breathing, fever, general discomfort
- Feeling weak, muscle weakness
- Intolerance to bright light
- Feeling abnormally tired
- Skin rash and itching, skin redness, reduced eyesight
- fits, pain in arms or legs, neck pain, back pain
Inform your doctor immediately if you experience any of the following side effects after receiving OMNIPAQUE INJECTION such as:
Severe allergic reactions (such as skin rashes with severe itching, itchy spots, blisters on skin and in mouth, red/itchy eyes, cough, running nose, sneezing, wheeziness, difficulty in breathing or tightness or pain in your chest, swelling of your face, dizziness)
- Signs of Encephalopathy (such as)
- Thyroid disorders
- A short-term decrease in formation of urine due to decreased kidney damage
How To Manage Side Effects
Nausea And Vomiting
To manage nausea and vomiting after iohexol therapy, it's recommended to stay hydrated by sipping clear fluids and eating small, bland meals. Resting in a comfortable position and avoiding strong odors can also help. If the symptoms persist or are severe, over-the-counter anti-nausea medications like ginger supplements or prescription medications might be necessary. Always consult a healthcare provider for proper guidance and if symptoms do not improve.
Warning & Precautions
Pregnancy
Monitoring requiredOMNIPAQUE INJECTION should be used in pregnancy only if the potential benefits outweigh the risks of iohexol injection. Therefore, inform your doctor before receiving OMNIPAQUE INJECTION if you are pregnant or think you may be pregnant.
Breastfeeding
Monitoring requiredOMNIPAQUE INJECTION can be used in breastfeeding women when considered necessary by the physician. Mothers can continue breastfeeding normally after examination with this medicine.
Driving and Using Machines
Use with CautionDo not drive or handle any heavy tools or machines if you experience dizziness or any side effect that affects your concentration after receiving OMNIPAQUE INJECTION.
Kidney
Use with CautionOMNIPAQUE INJECTION should be used with caution in patients having kidney problems. Therefore, consult your doctor for advice.
Liver
Use with CautionOMNIPAQUE INJECTION should be used with caution in patients having liver problems. Therefore, consult your doctor for advice.
Allergy
ContraindicatedBefore receiving OMNIPAQUE INJECTION, talk to your doctor if you have any allergies to Iohexol or any other contrast agent.
Lungs
Use with CautionOMNIPAQUE INJECTION should be used with caution in patients suffering from asthma. Therefore, consult your doctor for advice.
Heart Disease
Use with CautionOMNIPAQUE INJECTION should be used with caution in patients suffering from severe cardiac disease (involving heart or blood vessels) including high blood pressure, blood clots, stroke, and arrhythmias. Therefore, consult your doctor for advice.
Use In Pediatrics
Use with CautionOMNIPAQUE INJECTION should be used with caution in children (aged below 18 years) specifically in infants as a precaution. Therefore, consult your doctor for advice. Make sure your child drinks plenty of water or fluids before and after examination.
Use In Geriatrics
Use with CautionOMNIPAQUE INJECTION should be used with extreme caution in elderly patients (aged 65 years or above). Therefore, inform your doctor if you have any pre-existing disease conditions.
Others
OMNIPAQUE INJECTION should not be used if you:
- Have severe thyroid problems
Before receiving OMNIPAQUE INJECTION, inform your doctor if you:
- Have any thyroid problems
- Have ever had any allergies
- Have diabetes
- Have any brain disease (such as brain tumours, swelling or inflammation of the brain, problems in blood vessels supplying the brain, including blood clot or bleeding)
- Have ‘myasthenia gravis’ (a condition causing severe muscle weakness)
- Have phaeochromocytoma
- Have homocystinuria (a condition with increased excretion of the amino acid cysteine in urine)
- Have any problems with your blood or bone marrow
- Have a disease of immune system
- Have ever had alcohol dependence or addiction to any drugs
- Have epilepsy
- Have a thyroid function test in the next few weeks
- Have pulmonary hypertension
- Have paraproteinaemias (the presence of excessive amount of an abnormal protein in your blood)
- are having any blood or urine test on the same day
- have myeloma (cancer of bone marrow)
Interactions
A. Drug-Drug Interactions:
- Antidiabetic agents
- Cardiac agents (such as betablockers, vasoactive substances, ACE - enzyme inhibitors or angiotensin antagonists
- Interleukin-2 or interferons (used for immune system diseases)
- Antidepressants
Synopsis
| Drug | : | Iohexol |
| Pharmacological Category | : | Radio-Contrast Agent |
| Therapeutic Indication | : | Diagnostic agent |
| Dosage Forms | : | Injection, Infusion |
More Information
Storage
- Keep OMNIPAQUE INJECTION out of reach of children
- Store below 30°C
FAQs About OMNIPAQUE INJECTION
Q: What is OMNIPAQUE INJECTION used for?
A: OMNIPAQUE INJECTION is a radio-contrast agent used for diagnostic purposes only. It helps in diagnosing an illness by taking a clear picture of internal body parts which helps your doctor to tell if there is any abnormality in organ shape and size. It can be used for X-rays of urinary system, spine and blood vessels, including blood vessels supplying the heart, salivary gland, stomach and intestines and for scanning uterus, joints, breasts, ovaries, head and entire body (CAT scan).
Q: How OMNIPAQUE INJECTION works?
A: OMNIPAQUE INJECTION contains Iohexol which is a contrast agent used in medical imaging to help doctors see blood vessels, organs, and other tissues more clearly during scans like CT or X-rays. It works by absorbing X-rays due to its iodine content, making the areas where it is injected appear white on the scan. This contrast helps to differentiate various structures in the body, aiding in accurate diagnosis.
Q: Is OMNIPAQUE INJECTION safe?
A: Iohexol is generally safe, but like all medical procedures, it can have side effects. Most are mild, like nausea or a warm sensation. Serious allergic reactions are rare but possible.
Q: What are the common side effects of taking OMNIPAQUE INJECTION?
A: The most common side effects of receiving OMNIPAQUE INJECTION are feeling hot or flushed, shortness of breath, respiratory problems, headache, nausea, vomiting, diarrhea, dizziness, Inflammation of pancreas and pain around stomach, Increased/abnormal sweating and feeling cold. Consult your doctor if any of these side effect troubles you.
Q: Can OMNIPAQUE INJECTION be used during pregnancy?
A: OMNIPAQUE INJECTION should be used in pregnancy only if the potential benefits outweigh the risks of iohexol injection. Therefore, inform your doctor before receiving OMNIPAQUE INJECTION if you are pregnant or think you may be pregnant.
Q: What precautions must be taken before receiving OMNIPAQUE INJECTION?
A: Make sure to drink plenty of fluids before and after receiving OMNIPAQUE INJECTION, especially if you have diabetes, myeloma, kidney problems, aged above 65 years or have generally poor health conditions. Before receiving OMNIPAQUE INJECTION inform your doctor if you have liver, kidney or heart problems. You must also inform your doctor if you are pregnant or breastfeeding or having diabetes, epilepsy, thyroid problems, cancers of bone marrow, muscle weakness, brain problems, etc as a precaution. Inform your doctor immediately if you experience any allergic reactions after receiving OMNIPAQUE INJECTION.
Q: Which medicines should be avoided while taking OMNIPAQUE INJECTION?
A: Before receiving OMNIPAQUE INJECTION inform your doctor if you are taking any antidiabetic agents, heart medicines, (such as betablockers, vasoactive substances, ACE - enzyme inhibitors or angiotensin antagonists), Interleukins and interferons (used for immune system diseases) and antidepressants as a precaution.
Q: Can I take OMNIPAQUE INJECTION when I have thyroid problems?
A: Before receiving OMNIPAQUE INJECTION inform your doctor if you have any thyroid problems. OMNIPAQUE INJECTION should not be used in patients with severe thyroid problems.
Q: Can I take OMNIPAQUE INJECTION when I have cancer?
A: Before receiving OMNIPAQUE INJECTION inform your doctor if you have cancers of bone marrow as a precaution, as your doctor will monitor your health condition more closely.
References
1. Goodman and Gilman’s: The Pharmacological Basics of Therapeutics. 12th Edition. Thyroid and Anti-thyroid Drugs. Page-1153.
2. Iohexol. ScienceDirect. Clinical Biochemistry. 2013. [Accessed on 2nd September 2024] https://www.sciencedirect.com/topics/medicine-and-dentistry/iohexol
3. Omnipaque 140 mg I/ml solution for injection. GE Healthcare Limited. EMC.UK [Revised in March 2024]. [Accessed on 2nd September 2024] https://www.hpra.ie/img/uploaded/swedocuments/92f98b2a-368a-4753-a4a9-6805045a3113.pdf
4. OMNIPAQUE injection 140 and 350 mg iodine/mL. U.S. Food and Drug Administration (USFDA). [Revised in April 2023]. [Accessed on 2nd September 2024] https://www.gehealthcare.com/-/jssmedia/8a5df56afa4f4ea78352d110b227e956.pdf
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