Olmezest 40mg Tablet 10'S
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Introduction About OLMEZEST 40MG TABLET
Olmezest 40mg Tablet helps support healthy blood pressure levels by relaxing blood vessels. It combines effective components that work together to assist in maintaining cardiovascular wellness.
It contains Olmesartan which belongs to the group of medicines called Antihypertensives. Your doctor may advice you to take regular exercise such as walking or swimming, low salt diet, giving up smoking and alcohol drinking, which helps to reduce blood pressure effectively during management with this medicine.
OLMEZEST 40MG TABLET should be used with caution in patients with kidney, liver or heart problems. Your doctor may check your kidney function test, blood pressure and the amount of electrolytes (Ex. potassium) in the body prior to the management with OLMEZEST 40MG TABLET or at regular intervals along with the management.
It is not recommended in early pregnancy and must not be taken when more than 3 months pregnant and in breastfeeding women. This medicine should be used with caution in elderly patients (aged 65 years and above). The most common side effects are dizziness, nausea, headache, diarrhoea and stomach pain.
Uses Of OLMEZEST 40MG TABLET
- Used to manage high blood pressure
Benefits of OLMEZEST 40MG TABLET
- Effectively supports the lowering of high blood pressure by relaxing blood vessels, which helps ease blood flow and reduce strain on the heart.
- Helps in reducing the risk of serious cardiovascular events such as heart attacks and strokes by managing blood pressure levels.
- Assists in preventing kidney damage associated with elevated blood pressure conditions.
- May help reduce fluid retention and swelling by promoting the elimination of excess salt and water from the body.
- Supports overall cardiovascular health by aiding in maintaining optimal blood pressure.
- Suitable for use in patients who may benefit from combination medications for enhanced hypertension control.
How OLMEZEST 40MG TABLET Works
Olmezest 40mg contains Olmesartan Medoxomil, which helps relax blood vessels by blocking a natural substance called angiotensin II. Angiotensin II usually tightens blood vessels and raises blood pressure. By blocking its action, Olmezest allows blood vessels to stay open and relaxed. This helps blood flow more easily and supports healthy blood pressure levels. It also helps the body get rid of extra salt and water, reducing strain on the heart.
This way, Olmezest supports overall heart and blood vessel health in a gentle and effective manner.
How to use OLMEZEST 40MG TABLET
Recommended Dosage of Olmezest 40mg Tablet
The usual starting dose of Olmezest 40mg Tablet is one tablet once daily, or as prescribed by your healthcare provider. The dose may be adjusted based on individual response and medical condition, ensuring optimal support for blood pressure management.
How to Take Olmezest 40mg Tablet
Take Olmezest exactly as directed by your doctor. It can be taken with or without food, preferably at the same time every day to maintain consistent medicine levels in your body. Swallow the tablet whole with water; do not crush or chew.
Dosage Guidelines for Different Age Groups
- Adults: Typically one 40mg tablet once a day, adjusted as needed under medical supervision.
- Elderly: May require dose adjustments depending on kidney and liver function, as advised by the doctor.
- Pediatric use: Safety and effectiveness in children have not been established; consult a healthcare professional.
Timing and Frequency of Olmezest 40mg
Olmezest is usually taken once daily, either in the morning or evening, based on personal convenience and healthcare provider instructions. Consistency in timing helps maintain steady blood pressure control.
Important Instructions for Olmezest 40mg Administration
- Follow your healthcare provider’s instructions strictly.
- Do not stop taking Olmezest without consulting your doctor, even if you feel well.
- Keep regular medical appointments for blood pressure and kidney function monitoring.
- Inform your doctor about all other medications you are taking to avoid interactions.
Dosage Adjustments and Monitoring
Dosage may be adjusted based on blood pressure response and kidney function tests. Patients with kidney or liver conditions might need careful monitoring and modified doses. Always follow healthcare professional recommendations for safe use.
What if I forgot to take OLMEZEST 40MG TABLET
If you miss a dose, take it as soon as you remember on the same day. If it is almost time for the next dose, skip the missed dose—do not double up. Maintain your regular dosing schedule and consult your healthcare provider if you miss doses frequently.
Overdose
If you or anyone else accidentally takes too much of OLMEZEST 40MG TABLET, consult your doctor immediately or visit the nearby hospital. Overdosage symptoms are low blood pressure, fast heart rate, slow heart rate (bradycardia) if vagal nerve stimulation occurs.
Side Effects Of OLMEZEST 40MG TABLET
Common Side Effects of OLMEZEST 40MG TABLET:
- dizziness
- nausea, vomiting
- stomach pain, diarrhoea
- gastroenteritis (stomach flu)
- sore throat, cough
- runny or stuffy nose
- feeling of spinning (vertigo)
- muscular pain
Less Frequent Side Effects of Olmezest 40mg Tablet
- Fatigue or feeling unusually tired
- Mild muscle or joint pain
- Increased urination frequency
When to seek medical advice?
- allergic reactions (signs include swelling of the face, mouth and/or larynx (voice box), itching and rash)
- reduced blood pressure in susceptible individuals or because of allergic reaction which could cause severe light-headedness or fainting (more often in older people)
Warning & Precautions
Pregnancy
ContraindicatedOLMEZEST 40MG TABLET is not advised in early pregnancy and must not be taken when more than 3 months pregnant, as it may cause serious harm to the baby if used after the third month of pregnancy.
Breastfeeding
ContraindicatedOLMEZEST 40MG TABLET is not advised for use in breastfeeding women. Your doctor may choose another management especially if you want to breastfeed when your baby is a newborn or born prematurely.
Driving and Using Machines
Use with CautionDo not drive or operate any machines if you feel dizzy or sleepy after taking OLMEZEST 40MG TABLET.
Kidney
Use with CautionOLMEZEST 40MG TABLET should be taken cautiously in patients with kidney problems.
Liver
Consult your doctorOLMEZEST 40MG TABLET is not advised for use in patients with jaundice (yellowing of the skin and eyes). It should be used with caution in patients having liver disease.
Allergy
ContraindicatedDo not take OLMEZEST 40MG TABLET if you are allergic to Olmesartan or any of the other ingredients of this medicine.
Heart Disease
Use with CautionOLMEZEST 40MG TABLET should be taken cautiously in patients with heart failure or problems with heart valves or heart muscles.
Use In Pediatrics
Consult your doctorOLMEZEST 40MG TABLET is not recommended for use in children below 6 years of age. Your child’s doctor may adjust the dose based on the body weight of the child.
Use In Geriatrics
Use with CautionOLMEZEST 40MG TABLET should be use cautiously in elderly patients (aged 65 years and above
Other Warnings for OLMEZEST 40MG TABLET
Before taking OLMEZEST 40MG TABLET, inform your doctor if you:
- severe vomiting, diarrhoea or if you are on a low salt diet
- take high doses of diuretics for the management
- problems with adrenal glands
- increased levels of potassium in the blood
Who should not take [GBNKEYWORD
OLMEZEST 40MG TABLET is not recommended for use if you:
- problems with the drainage of the bile from the gallbladder ((biliary obstruction Ex. gallstones)
Drug - Drug interaction
- Aliskiren: Avoid using Olmezest with aliskiren, especially in patients with diabetes or kidney problems, due to increased risk of side effects.
- Potassium Supplements and Salt Substitutes: Use caution as Olmezest may increase potassium levels, raising the risk of hyperkalemia.
- Diuretics (Water Pills): Combining with diuretics can increase the risk of low blood pressure and kidney problems, requiring dose adjustments.
- Nonsteroidal Anti-Inflammatory Drugs (NSAIDs): Such as ibuprofen and naproxen, may reduce the blood pressure-lowering effect of Olmezest and worsen kidney function.
- Lithium: Olmezest may increase lithium levels, enhancing toxicity risk.
- Other Blood Pressure Medications: Combining with ACE inhibitors, ARBs, or other antihypertensives requires medical supervision due to additive effects on blood pressure and kidney function.
- Colesevelam: May affect absorption of Olmesartan if taken together.
- Certain Antibiotics and Antifungals: Drugs like ciprofloxacin and clarithromycin may interact, necessitating monitoring.
Drug - Food interaction
- Alcohol: May increase dizziness when taken with Olmezest.
- Grapefruit Juice: Generally not recommended as it may interfere with medication efficacy.
Synopsis
| Drug | : | Olmesartan |
| Pharmacological Category | : | Angiotensin Receptor Blockers |
| Therapeutic Indication | : | Hypertension |
| Dosage Forms | : | Tablet |
More Information
Comparison with similar medication
|
Feature |
Olmezest (Olmesartan) |
Losartan |
Valsartan |
Telmisartan |
|
Effectiveness |
Generally shows greater reduction in blood pressure compared to losartan and valsartan, with faster onset of action |
Effective but may have a shorter half-life and slightly less potent BP lowering effect |
Effective, often used in heart failure as well |
Strong BP control with longer half-life, also reduces cardiovascular risks in diabetics |
|
Dosing Frequency |
Once daily, with a long half-life supporting 24-hour control |
Usually once daily |
Usually once daily |
Once daily, longest half-life among ARBs |
|
Combination Products |
Available with hydrochlorothiazide (Benicar HCT), amlodipine (Azor), or both (Tribenzor) |
Available with hydrochlorothiazide (Hyzaar) |
Commonly combined with hydrochlorothiazide (Diovan HCT) |
Combined with hydrochlorothiazide (Micardis HCT) and amlodipine |
|
Additional Benefits |
Shows potentially stronger anti-inflammatory effects and kidney protection |
Widely used, well-studied |
FDA approved for heart failure |
Approved to reduce cardiovascular events and diabetic nephropathy progression |
|
Side Effects |
Similar to other ARBs; rare risk of sprue-like enteropathy |
Common ARB side effects, less associated with sprue-like enteropathy |
Comparable side effect profile |
Similar safety profile, long-acting benefits |
|
Use in Special Populations |
Suitable under medical supervision, dose adjustments for elderly or kidney impairment |
Widely used including in patients with kidney issues |
Used broadly with careful monitoring |
Beneficial in patients with metabolic syndrome |
FAQs About OLMEZEST 40MG TABLET
Q: What is Olmezest 40mg Tablet used for?
A: Olmezest is used to support the management of high blood pressure (hypertension), helping to keep blood vessels relaxed and promote healthy blood flow.
Q: How should I take Olmezest 40mg Tablet?
A: Take Olmezest once daily, with or without food, at the same time each day. Swallow the tablet whole with water — do not crush or chew it.
Q: What should I do if I miss a dose?
A: Take the missed dose as soon as you remember on the same day. If it is near the time for your next dose, skip the missed dose. Do not double the dose.
Q: Are there any common side effects?
A: Some may experience dizziness, headache, or mild gastrointestinal symptoms. Contact a healthcare provider if side effects persist or worsen.
Q: Can I take Olmezest with other medications?
A: Inform your doctor about all medicines and supplements you take, as some may interact. Avoid potassium supplements or NSAIDs without medical advice.
Q: Is Olmezest safe during pregnancy?
A: Olmezest should not be used during pregnancy as it may harm the unborn baby. Inform your healthcare provider if you are pregnant or planning to become pregnant.
Q: How long will I need to take Olmezest?
A: Treatment is often long-term to maintain healthy blood pressure. Do not stop without consulting your healthcare provider.
Q: Can Olmezest cause serious side effects?
A: Serious allergic reactions and kidney problems are rare. Seek immediate medical help if you experience swelling, difficulty breathing, or significant swelling in your legs or feet.
Q: Can OLMEZEST 40MG TABLET be used to manage high blood pressure?
A: OLMEZEST 40MG TABLET is used to manage high blood pressure. It contains olmesartan which helps to relax the blood vessels and then normalize the blood pressure.
Q: Can OLMEZEST 40MG TABLET be given to children and adolescents?
A: OLMEZEST 40MG TABLET is not recommended for use in children below 6 years of age. Your child’s doctor may adjust the dose based on the body weight of the child.
Q: What happens if I stop taking OLMEZEST 40MG TABLET?
A: Do not stop taking the medicine without talking to your doctor first. Stopping this medicine suddenly can cause your blood pressure to spike up and may increase the risk for heart conditions.
Q: Can OLMEZEST 40MG TABLET be taken by patients with kidney problems?
A: It should be taken with caution in patients with kidney problems. Your doctor may monitor your kidney function test before and during management with this medicine to manage the risk of kidney damage or any unusual effects due to the accumulation of medicine in the body.
Q: What precautions do I need to follow while taking OLMEZEST 40MG TABLET?
A: Patients taking OLMEZEST 40MG TABLET must inform their doctor about their pre-existing disease conditions like kidney, heart or liver problems.
References
1. KD. Tripathi. Drugs Affecting Renin Angiotensin System. Essentials of medical pharmacology. Eighth edition. 2019. Page –535-538.
2. Xiaoshen Zhang, Han Zhang, Yuxia Ma, Wenliang Che and Michael R. Hamblin. Management of Hypertension Using Olmesartan Alone or in Combination. NIH National Library of Medicine, National center for biotechnology information. PubMed Central. June 2017. [Accessed on 21st August 2025] 
3. Kazuomi Kario, Ikuo Saito, Toshio Kushiro, Satoshi Teramukai, Mai Yaginuma, Yoshihiro Mori, Yasuyuki Okuda, Fumiaki Kobayashi and Kazuyuki Shimada. Persistent olmesartan-based blood pressure–lowering effects on morning hypertension in Asians: the HONEST study. NIH National Library of Medicine, National center for biotechnology information. PubMed Central. May 2016. [Accessed on 21st August 2025] 
4. Accord Healthcare Limited. Electronic Medicines Compendium (EMC). [Revised in February 2022] [Accessed on 21st August 2025]
5. Daiichi Sankyo. U.S. Food & Drug Administration. [Revised in May 2011] [Accessed on 21st August 2025]
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