Nodosis Gst 500mg Tablet 10'S

Introduction About NODOSIS GST 500MG TABLET

Nodosis GST 500mg Tablet is an alkalinizing agent that helps restore the body’s acid-base balance in conditions linked with increased acidity. It contains Sodium Bicarbonate, which works by neutralizing excess acid in the blood, stomach, or urine. This makes it beneficial in situations like metabolic acidosis, heartburn, indigestion, urinary alkalinization, and certain intoxications involving acidic compounds. By helping maintain optimal pH levels, it supports normal cellular metabolism and promotes kidney function efficiency.

It is generally recommended for individuals who experience acidic imbalance, digestive discomfort, or require urinary pH adjustment as advised by their doctor. It is suitable for patients needing support in managing acid-related concerns caused by underlying metabolic or dietary conditions. The tablet should be taken after meals with a glass of water to minimize gastric irritation. The dosage and duration depend on the patient’s medical needs and physician’s advice. Avoid taking it with acidic drinks or immediately after large meals to maintain its neutralizing effect.

Before taking Nodosis GST 500mg Tablet, patients should inform their healthcare provider about any existing kidney, liver, or heart conditions, or if they are on a low-sodium diet. Overuse or prolonged intake without guidance may lead to electrolyte imbalance or increased sodium levels in the blood. It is important not to self-adjust the dose or use it for extended periods without medical supervision. Always maintain a gap of at least 2 hours between this tablet and other oral medicines to avoid potential drug interactions.

It should be used during pregnancy and breastfeeding only under medical supervision. Your doctor will weigh the benefits and potential risks before recommending its use. Most people tolerate this medicine well, but some may experience nausea, bloating, mild stomach discomfort, or increased thirst. If any unusual symptoms occur, it is advisable to seek medical advice promptly. Overall, when taken as prescribed, Nodosis GST 500mg Tablet supports healthy acid balance and contributes to better metabolic and digestive health.

Uses Of NODOSIS GST 500MG TABLET

• To manage metabolic acidosis, certain intoxications (Ex. methyl alcohol, phenobarbital, salicylates), severe diarrhoea, and haemolytic reactions requiring alkalinization of the urine
• As an adjunct in hyperkalaemia
• To correct acidosis
• in advanced cardiac life support (ACLS) during cardiopulmonary resuscitation (CPR)

Benefits of NODOSIS GST 500MG TABLET

Nodosis GST 500mg Tablet for Metabolic Acidosis

Nodosis GST 500mg Tablet is often used to support individuals with metabolic acidosis, a condition where the body produces too much acid or when the kidneys cannot remove enough acid. It helps restore the body’s normal acid-base balance by neutralizing excess acid levels. By improving the body’s buffering capacity, this tablet supports cellular and metabolic stability. It is generally used under the guidance of a healthcare professional for better metabolic balance.

Nodosis GST 500mg Tablet for Indigestion and Heartburn

For people experiencing discomfort from indigestion or heartburn, Nodosis GST 500mg Tablet can help by reducing excessive stomach acid. Its alkaline nature helps in relieving the burning sensation and bloating often linked to acidity or reflux issues. This supportive action helps improve digestive comfort and eases the feeling of fullness. Regular use should only be as advised by a healthcare provider to maintain proper acid balance in the stomach.

Nodosis GST 500mg Tablet for Urinary Alkalinization

Nodosis GST 500mg Tablet plays an important role in urinary alkalinization a process that increases the pH of urine. This helps make the urine less acidic, supporting better kidney function and easing the excretion of certain substances. It can be useful for individuals with high uric acid levels or those needing urine pH management for medical reasons. Always consult your doctor before using it for urinary health purposes.

Nodosis GST 500mg Tablet for Adjunct Treatment

Nodosis GST 500mg Tablet is often recommended as an adjunct or supportive option alongside other prescribed medications. Its alkalinizing property helps maintain pH balance in the body, improving the overall effectiveness of certain therapeutic plans. It may assist in stabilizing body functions affected by acid-base disturbances. The tablet should be used only under medical supervision to ensure compatibility with other ongoing treatments.

Nodosis GST 500mg Tablet for Intoxications

Nodosis GST 500mg Tablet can be used under medical guidance in certain intoxication cases, especially where acidic substances or drugs are involved. By alkalinizing the blood and urine, it assists in neutralizing acids and promoting faster elimination of toxins. This supportive mechanism can help reduce the harmful impact of specific toxic agents. Such use should always be guided by healthcare professionals in controlled clinical settings.

How NODOSIS GST 500MG TABLET Works

Mechanism of Action of Nodosis GST 500mg Tablet

Nodosis GST 500mg Tablet works primarily by neutralizing excess acid in the body through its active ingredient, Sodium Bicarbonate, an alkalinizing agent. When dissolved, it releases bicarbonate ions, which combine with hydrogen ions in the body to form carbonic acid. This carbonic acid then breaks down into water and carbon dioxide, which are safely eliminated through the lungs and kidneys.

This mechanism helps restore the acid-base balance in the blood and tissues, relieving acidity-related discomfort and maintaining optimal pH levels. Additionally, the alkalinization of urine helps enhance the excretion of acidic drugs and toxins, supporting detoxification processes. Overall, Nodosis GST 500mg Tablet promotes internal balance by reducing acid overload and aiding in the smooth functioning of metabolic and renal systems.

How to use NODOSIS GST 500MG TABLET

How to Take Nodosis GST 500mg Tablet

• Take Nodosis GST 500mg Tablet exactly as advised by your doctor or as directed on the product label.
• It is usually taken after meals with a full glass of water to reduce stomach irritation.
• Swallow the tablet whole; do not crush, chew, or break it unless instructed by your healthcare provider.
• The dosage and duration depend on your medical condition, age, and response to the medicine.
• Avoid taking it together with acidic beverages like orange juice or soft drinks, as they may reduce its effectiveness.
• If you are on other medicines, maintain a gap of at least 2 hours before or after taking Nodosis GST 500mg Tablet to avoid interaction.
• Do not exceed the recommended dose or use it for an extended period without medical supervision.

What if I forgot to take NODOSIS GST 500MG TABLET

• Take the missed dose as soon as you remember, unless it is almost time for your next scheduled dose.
• If it is close to your next dose, skip the missed tablet and continue with your regular schedule.
• Do not take a double dose to make up for the missed one, as this may cause electrolyte imbalance or other side effects.
• For occasional use (as needed for heartburn or gas), simply take the tablet when symptoms appear.
• Keep a reminder or note to avoid missing doses if you are using it regularly.
• If you frequently forget doses or symptoms persist, consult your doctor for advice.

Overdose

An overdose of Nodosis GST 500mg Tablet may cause nausea, vomiting, stomach pain, severe bloating, muscle cramps, weakness, or confusion. You may also experience irregular heartbeat, restlessness, or unusual tiredness due to electrolyte imbalance. In rare cases, excessive intake can lead to metabolic alkalosis, causing rapid or irregular breathing and dizziness. If any of these symptoms occur, seek immediate medical attention.

Side Effects Of NODOSIS GST 500MG TABLET

Common side effects of Nodosis Gst 500mg tablet:

• Increased thirst
• Dry mouth
• Bloating, gas
• Nausea
• Loss of appetite
• Stomach cramps or mild stomach discomfort

When to Seek Medical Attention?

Stop taking Nodosis Gst 500mg tablet and contact your doctor immediately if you experience any of the following side effects:

• Persistent nausea, vomiting, or stomach pain: These may indicate irritation or excessive alkalinity in the stomach.
• Severe bloating, swelling of the face, feet, or ankles: Could signal fluid retention or sodium overload, especially in patients with kidney or heart issues.
• Muscle cramps, weakness, confusion, or irregular heartbeat: May suggest electrolyte imbalance such as low potassium or high sodium levels.
• Unusual fatigue, dizziness, or difficulty breathing: Could indicate changes in blood pH or fluid build-up in the body.
• Severe headache or restlessness: These symptoms may be linked to metabolic alkalosis, a condition where the body becomes too alkaline.
• Allergic reactions: Stop taking the medicine immediately if you notice rash, itching, swelling, or trouble breathing.
• Worsening of existing health conditions: People with kidney disease, liver problems, hypertension, or heart failure should report any deterioration in their symptoms promptly.

How To Manage Side Effects

Dry Mouth

• Stay Hydrated Throughout the Day: Drink plenty of water at regular intervals to keep your mouth moist. Sip small amounts frequently instead of drinking large quantities at once. You can also keep a water bottle nearby to stay hydrated during work or sleep hours.
• Chew Sugar-Free Gum or Lozenges: Chewing sugar-free gum or sucking on sugar-free lozenges helps stimulate saliva production. Opt for products containing xylitol, which not only boosts moisture but also helps reduce the risk of cavities.
• Use a Humidifier at Night: Running a cool-mist humidifier in your bedroom adds moisture to the air and prevents your mouth from drying out while you sleep. It’s especially helpful in air-conditioned or heated environments.
• Rinse with Alcohol-Free Mouthwash: Choose an alcohol-free, moisturizing mouthwash containing ingredients like aloe vera or glycerine. Alcohol-based rinses can worsen dryness, so opt for soothing alternatives designed for dry mouth relief
• Avoid Caffeine, Alcohol, and Tobacco: Coffee, tea, alcohol, and smoking can dehydrate the oral tissues and worsen dryness. Try switching to herbal teas or decaffeinated drinks and avoid smoking to protect your oral health.
• Eat Moist, Soft Foods: Include foods that are naturally hydrating such as soups, yogurt, smoothies, or stews. Avoid overly salty, dry, or spicy foods as they can irritate the mouth and worsen dryness.
• Practice Good Oral Hygiene: Brush your teeth twice daily with fluoride toothpaste and gently clean your tongue. Regular oral hygiene helps prevent infections, bad breath, and discomfort often linked with dry mouth.

Nausea And Vomiting

• Ginger Tea or Raw Ginger: Ginger is one of the best-known natural remedies for nausea. You can chew a small piece of fresh ginger or sip warm ginger tea. It helps soothe the stomach and reduce the urge to vomit by promoting better digestion and reducing stomach contractions.
• Peppermint or Mint Leaves: The menthol in peppermint has a cooling and calming effect on the stomach. You can drink peppermint tea, chew fresh mint leaves, or inhale peppermint essential oil to help relieve nausea sensations.
• Stay Hydrated with Clear Fluids: Drink small sips of water, coconut water, or clear soup frequently to prevent dehydration, especially if nausea is accompanied by vomiting. Avoid carbonated or sugary drinks as they may worsen stomach discomfort.
• Eat Small, Light Meals: Avoid heavy, oily, or spicy foods. Instead, have small portions of bland foods such as rice, toast, bananas, or applesauce. Eating slowly and in smaller amounts can prevent overloading your digestive system.
• Try Lemon or Citrus Aromas: The scent of fresh lemon or citrus fruits can help reduce nausea for many people. You can inhale the aroma, sip diluted lemon water, or add a few drops of lemon juice to warm water for mild relief.
• Rest and Fresh Air: Sometimes nausea worsens with motion or poor ventilation. Rest in a cool, quiet, and well-ventilated place, or step outside for fresh air. Avoid lying flat immediately after eating; instead, sit upright for better digestion.
• Apply Acupressure: Gentle pressure on the P6 (Neiguan) point located on the inner wrist about three finger-widths below the palm can help reduce nausea and vomiting. You can use your thumb to apply light pressure for 1–2 minutes.

Warning & Precautions

Pregnancy

Consult your doctor

Nodosis GST 500mg Tablet should be used during pregnancy only if clearly needed and under medical advice. Excessive intake may alter the acid-base balance in the body, which could affect both mother and baby. Always consult your doctor before use during pregnancy.

Breastfeeding

Consult your doctor

It is not known whether the components of Nodosis GST 500mg Tablet pass into breast milk. Since sodium bicarbonate may affect the infant’s acid-base balance, breastfeeding women should use this medicine only on a doctor’s recommendation.

Driving and Using Machines

Use with Caution

Nodosis GST 500mg Tablet does not usually affect alertness or coordination. However, if you experience dizziness, headache, or unusual tiredness after taking it, avoid driving or operating heavy machinery until you feel better.

Kidney

Use with Caution

Patients with kidney problems should use Nodosis GST 500mg Tablet with caution. The medicine contains sodium, which may accumulate and cause electrolyte imbalance or fluid retention in those with impaired kidney function. Dose adjustment and regular monitoring of electrolytes are advisable.

Liver

Consult your doctor

Individuals with liver impairment should take Nodosis GST 500mg Tablet only under medical supervision. The sodium content may worsen fluid retention or influence metabolic balance in severe liver conditions. Inform your doctor about any liver issues before starting the medicine.

Allergy

Contraindicated

Do not take Nodosis GST 500mg Tablet if you are allergic to sodium bicarbonate, simethicone, or any of its inactive ingredients. Seek medical attention immediately if you experience rash, itching, swelling, or difficulty breathing after taking the medicine.

Lungs

Consult your doctor

While not directly affecting lung function, patients with respiratory conditions such as chronic obstructive pulmonary disease (COPD) or asthma should consult their doctor before use, as metabolic changes may indirectly affect breathing patterns.

Heart Disease

Use with Caution

People with heart conditions, including high blood pressure, heart failure, or fluid retention, should use Nodosis GST 500mg Tablet cautiously. Its sodium content can increase blood pressure and may worsen heart symptoms if taken in excess.

Use In Pediatrics

Consult your doctor

Nodosis GST 500mg Tablet is not recommended for use in children unless prescribed by a doctor. The dosage must be carefully calculated based on age and weight.

Use In Geriatrics

Monitoring required

Elderly patients should take Nodosis GST 500mg Tablet under strict medical guidance. Due to the risk of electrolyte imbalance or fluid overload, the lowest effective dose is usually recommended with regular monitoring.

Who should not take [GBNKEYWORD

Nodosis Gst 500mg tablet is not recommended for use if you have:

• Low calcium levels (hypocalcaemia): The medicine may increase the risk of muscle twitching or spasms in such cases.
• Metabolic alkalosis: Do not use if your body fluids are already too alkaline, as this medicine may worsen the condition.
• Salt-restricted diets: Patients on a low-sodium diet should consult their doctor before using it.

Safety Advice

• Avoid taking this tablet immediately after large meals, as it may increase stomach distension or discomfort.
• Do not use antacids or other alkali-containing medicines simultaneously unless prescribed, to prevent excessive alkalinity.
• Monitor blood pressure regularly if you have hypertension, as the sodium content may elevate it.
• Avoid using this medicine for acid reflux linked to overeating or alcohol use without consulting a doctor.
• If you are on a weight-loss or low-salt diet, inform your healthcare provider before taking this tablet.
• If you are scheduled for lab tests, inform the technician that you are taking sodium bicarbonate, as it can alter some test results.
• Avoid long-term use in patients with weak bones (osteoporosis), since chronic alkalinity may affect calcium balance.
• In case of frequent heartburn or gas even after using this tablet, consult a doctor instead of increasing the dose.
• Store the medicine tightly closed, away from moisture and children’s reach to prevent accidental ingestion.

Diet and Lifestyle Advice

• Eat small, frequent meals: Instead of heavy meals, choose lighter portions spread throughout the day to reduce stomach acid build-up and bloating.
• Avoid gas-forming foods: Limit intake of beans, cabbage, carbonated drinks, and fried or spicy foods, as they can worsen acidity and bloating.
• Stay hydrated: Drink plenty of water throughout the day to help maintain electrolyte balance and support digestion.
• Limit sodium-rich foods: Since Nodosis GST contains sodium bicarbonate, avoid salty foods like pickles, chips, and processed snacks to prevent fluid retention.
• Avoid caffeine: It can increase stomach acid production and reduce the effectiveness of the medicine.
• Eat slowly and chew food well: This helps reduce gas formation and supports better digestion.
• Maintain a healthy weight: Excess weight can increase pressure on the stomach, leading to acidity and reflux.
• Avoid lying down immediately after eating: Wait at least 2–3 hours before lying down or sleeping to prevent acid reflux.
• Exercise regularly: Gentle activities like walking, yoga, or stretching after meals can help improve digestion and reduce bloating.
• Manage stress: Stress can worsen acidity. Try relaxation techniques such as deep breathing, meditation, or light physical activity.

1. Nodosis GST 500mg Tablet and Proton Pump Inhibitors (PPIs)

2. Nodosis GST 500mg Tablet and H2 Blockers

Drug - Drug interaction

1. Interaction with Tetracycline Antibiotics (e.g., Doxycycline, Tetracycline)

• Interaction: Sodium bicarbonate can reduce the absorption of tetracyclines, making them less effective.
• Management: Take Nodosis GST at least 2 hours before or after the antibiotic. Follow your doctor’s instructions carefully.

2. Interaction with Iron Supplements

• Interaction: High stomach alkalinity may decrease iron absorption.
• Management: Take iron supplements 2–3 hours apart from Nodosis GST. Pair with vitamin C if advised to improve absorption.

3. Interaction with Antifungal Medications (e.g., Ketoconazole, Itraconazole)

• Interaction: Reduced stomach acidity can lower the absorption of antifungals that require an acidic environment.
• Management: Maintain a 2-hour gap between the antifungal and Nodosis GST. Follow your doctor’s guidance.

4. Interaction with Digoxin

• Interaction: Changes in electrolytes caused by sodium bicarbonate may increase the risk of digoxin toxicity.
• Management: Monitor heart rate and digoxin levels closely. Consult your doctor if unusual symptoms occur.

5. Interaction with Other Antacids or Alkalizing Agents

• Interaction: Combining multiple antacids may cause excessive alkalinity, leading to electrolyte imbalance or metabolic disturbances.
• Management: Avoid using multiple antacids at the same time. Follow the prescribed dosing schedule carefully.

6. Interaction with Salicylates (e.g., Aspirin)

• Interaction: Sodium bicarbonate may increase absorption of salicylates, increasing the risk of side effects.
• Management: Maintain a time gap between aspirin and Nodosis GST and monitor for unusual symptoms.

7. Interaction with Medications Requiring Acidic Stomach (e.g., Atazanavir)

• Interaction: Reduced stomach acidity may lower the absorption and effectiveness of these drugs.
• Management: Take these medications 2–3 hours apart from Nodosis GST. Consult your doctor for alternatives if necessary.

Drug - Food interaction

1. Interaction with High-Sodium Foods (e.g., pickles, processed snacks, salted foods)

• Interaction: Sodium bicarbonate in Nodosis GST may add to dietary sodium, potentially increasing blood pressure or causing fluid retention in sensitive individuals.
• Management: Limit intake of high-sodium foods while using this medicine. Maintain a balanced diet and monitor for swelling or increased blood pressure.

2. Interaction with Carbonated Drinks (e.g., soda, sparkling water)

• Interaction: Carbonated beverages can increase bloating and gas, reducing the comfort effect of the medicine.
• Management: Avoid carbonated drinks around the time of taking Nodosis GST to maximize relief from gas and bloating.

3. Interaction with Caffeine-Containing Foods and Drinks (e.g., coffee, tea, energy drinks)

• Interaction: Caffeine can increase stomach acid production, which may counteract the antacid effect of Nodosis GST.
• Management: Limit caffeine intake, especially close to doses of Nodosis GST, to maintain its effectiveness.

4. Interaction with Fatty or Fried Foods

• Interaction: Heavy, oily foods may delay stomach emptying and worsen bloating, reducing the effectiveness of Nodosis GST.
• Management: Opt for lighter meals and avoid large amounts of fried or fatty foods while using the tablet.

5. Interaction with Spicy Foods

• Interaction: Spices can irritate the stomach lining, potentially worsening heartburn and acidity symptoms.
• Management: Reduce intake of very spicy foods during therapy and observe whether symptoms improve with Nodosis GST.

6. Interaction with Alcohol

• Interaction: Alcohol can increase stomach acid and may irritate the digestive system, reducing the effectiveness of Nodosis GST.
• Management: Avoid or limit alcohol consumption while taking the tablet to achieve better symptom relief.

7. Interaction with Dairy Products (e.g., milk, cheese, yogurt) in Excess

• Interaction: Large amounts of dairy can temporarily buffer stomach acid but may increase calcium and magnesium levels, interacting with sodium bicarbonate’s effect.
• Management: Moderate dairy intake and maintain a balanced diet while using the medicine.

Synopsis

More Information

• Keep Nodosis GST Tablet out of the reach and sight of children
• Store below 30°C away from light

FAQs About NODOSIS GST 500MG TABLET

References

1.Steadfast Medishield. Nodosis (Sodium bicarbonate). [Accessed on 17th October 2025] 

2.  WebMD. Nodosis (Sodium bicarbonate). [Accessed on 17th October 2025] 

3. Niluk Leon Senewiratne; Allison Woodall; Ahmet S. Can. Nododsis (Sodium bicarbonate). NIH National Library of Medicine, National centre for biotechnology information. [Revised in 12th February 2024][Accessed on 17th October 2025]

Author Details

Written By Dr. Jeenal Rajani - Pharm.D.

Reviewed For Accuracy By Dr. Vrushabhakumar Jitendra Shah. - MBBS

Last updated on 25 Mar 2023 | 04:06 PM(IST)