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Introduction About NEBIRITE 5 TABLET
NEBIRITE 5 TABLET is used in the management of essential hypertension (high blood pressure). It also controls heart pumping strength and in the management of mild and moderate chronic heart failure (above 70 years of age). It contains Nebivolol which belongs to the group of medicines called Beta blockers.
Along with NEBIRITE 5 TABLET, your doctor might advise you to make certain lifestyle changes, such as healthy eating, sleep, weight and stress management, quitting smoking and alcohol. Your doctor may ask you to undergo some blood tests before starting the management with the medicine. It is not recommended for use in patients having liver, kidney, lungs, or heart disease, circulation problems, unmanaged pheochromocytoma, or diabetic ketoacidosis.
Before starting the management with NEBIRITE 5 TABLET, inform your doctor if you have diabetes or an overactive thyroid gland. No studies of this medicine were conducted in pregnant women. Use of this medicine during pregnancy only if the potential benefit justifies the potential risk to the fetus. It is not recommended for use in nursing mother. Some of the most common side effects are headache, dizziness, fatigue, weakness, and insomnia. Inform your doctor if any of the above side effects worsen.
Uses Of NEBIRITE 5 TABLET
It is used to manage:
- high blood pressure (hypertension)
- mild and moderate chronic heart failure in addition to standard therapies in elderly patients above 70 years
How NEBIRITE 5 TABLET Works
NEBIRITE 5 TABLET works specifically on the heart by slowing down the heart rate and making the heart more efficient at pumping blood around the body. This results in a lowering of the blood pressure.
How to use NEBIRITE 5 TABLET
- Take NEBIRITE 5 TABLET as advised by your doctor
- Swallow the medicine with a glass of water. Do not crush or chew the medicine
- Your doctor will decide the correct dose and duration for you depending upon your age, body weight, and disease condition
Side Effects Of NEBIRITE 5 TABLET
Common Side Effects of NEBIRITE 5 TABLET:
- dizziness
- tiredness
- diarrhoea, constipation
Stop taking NEBIRITE 5 TABLET and contact your doctor immediately if you experience any of the following side effects:
- severe allergic reactions, with generalized skin eruptions (hypersensitive reactions)
- rapid onset of swelling around the lips, eyes, or tongue with sudden difficulties in breathing (angioedema)
- skin rash involving pale red, raised, itchy bumps of allergic or non-allergic causes
- breathlessness, such as in asthma, tightening of the chest, difficulty breathing, or wheezing
Warning & Precautions
Pregnancy
Consult your doctorNo studies of this medicine were conducted in pregnant women. Use of NEBIRITE 5 TABLET during pregnancy only if the potential benefit justifies the potential risk to the fetus.
Breastfeeding
Consult your doctorIt is not known whether this medicine is excreted in human milk. NEBIRITE 5 TABLET is not recommended during nursing.
Driving and Using Machines
Use with CautionDo not drive or operate any machines if you experience dizziness or fatigue after taking NEBIRITE 5 TABLET.
Kidney
Use with CautionNEBIRITE 5 TABLET should be used with caution in patients with severe kidney disease or patients who are undergoing dialysis.
Liver
ContraindicatedNEBIRITE 5 TABLET is not recommended for use in patients with liver disease.
Allergy
ContraindicatedDo not take NEBIRITE 5 TABLET if you are allergic to Nebivolol or to any other ingredients of this medicine.
Lungs
ContraindicatedNEBIRITE 5 TABLET is not recommended for use in patients with lung disease such as asthma or wheezing.
Heart Disease
Consult your doctorNEBIRITE 5 TABLET is not recommended in patients having heart diseases such as low blood pressure, very slow heartbeat, heart rhythm problems, or heart failure. It should be used with caution in patients having Prinz metal angina, unmanaged chronic heart failure, and first-degree heart block.
Use In Pediatrics
Consult your doctorSafety and effectiveness in pediatric patients have not been established. Pediatric studies in ages newborn to 18 years old have not been conducted because of incomplete characterization of developmental toxicity and possible adverse effects on long-term fertility.
Use In Geriatrics
Consult your doctorNo overall differences in efficacy or in the incidence of adverse events were observed between older and younger patients.
Others
It is not recommended for use if you:
- have serious circulation problems in arms or legs
- have unmanaged pheochromocytoma (tumor of the adrenal gland)
- have diabetic ketoacidosis
Before taking NEBIRITE 5 TABLET, inform your doctor if you:
- have diabetes
- have an overactive thyroid gland
- have planned surgery and require anesthesia
- have lactose intolerance
Interactions
A. Drug-Drug interactions:
Before taking the medicine, inform your doctor if you are taking any of the following medicine:
- Antihypertensive agents (Ex. amiodarone, amlodipine, cibenzoline, clonidine, digoxin, diltiazem, disopyramide, felodipine, flecainide, guanfacin, nicardipine, nimodipine, nitrendipine, propafenone, quinidine, rilmenidine, verapamil, hydroquinidine, lacidipine, lidocaine, methyldopa, mexiletine, moxonidine, nifedipine)
- Sedative-hypnotic agents (Ex. barbiturates, phenothiazine, thioridazine)
- Antidepressants (Ex. amitriptyline, paroxetine, fluoxetine)
- medicines used for anesthesia during operation
- medicines used for asthma, blocked nose, glaucoma, or dilation
- antispasmodic agents (Ex. baclofen)
- H2 blockers (Ex. cimetidine)
- Cytoprotectants (Ex. amifostine)
- Anti-malarial agents (Ex. mefloquine)
Overdosage:
If you or anyone else accidentally takes too much of NEBIRITE 5 TABLET, consult your doctor immediately or visit the nearby hospital.
Synopsis
| Drug | : | Nebivolol |
| Pharmacological Category | : | Selective Beta-blockers |
| Therapeutic Indication | : | Hypertension, Mild to moderate chronic heart failure |
| Dosage Forms | : | Tablet |
FAQs About NEBIRITE 5 TABLET
Q: What is NEBIRITE 5 TABLET used for?
A: NEBIRITE 5 TABLET is used in the management of essential hypertension (high blood pressure). It also controls heart pumping strength and in the management of mild and moderate chronic heart failure (above 70 years of age).
Q: Can I stop taking NEBIRITE 5 TABLET on my own?
A: No, do not alter or discontinue the daily dose of NEBIRITE 5 TABLET after feeling better without consulting your doctor. Your doctor will decide the correct dose and duration of this medicine for you depending upon your age, body weight, and disease condition.
Q: Does NEBIRITE 5 TABLET have side effects?
A: NEBIRITE 5 TABLET can cause tiredness, diarrhea, constipation. Consult a doctor immediately if any of the effects worsen or continue for a long time.
Q: Can NEBIRITE 5 TABLET cause constipation?
A: Yes, constipation is a common side effect of taking NEBIRITE 5 TABLET. In case you are suffering from constipation, take foods rich in fiber in your diet for better digestion, such as fresh fruits, vegetables, and whole grain cereals, and drink plenty of fluids. Exercise more regularly and stay active.
Q: How and when should NEBIRITE 5 TABLET be taken?
A: Take NEBIRITE 5 TABLET as advised by your doctor. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight, and disease condition.
Q: Can NEBIRITE 5 TABLET cause headache?
A: Yes, headache is one of the most common side effects of taking NEBIRITE 5 TABLET. In case you are experiencing a headache after taking the medicine, try to rest and relax. Keep drinking plenty of fluids, such as water or electrolytes. Apply a pain-relieving balm on the forehead if needed. Do not consume too much alcohol. Consult your doctor if the headache persists for a long time.
Q: Can NEBIRITE 5 TABLET be taken by pregnant women?
A: No studies of this medicine were conducted in pregnant women. Use of NEBIRITE 5 TABLET during pregnancy only if the potential benefit justifies the potential risk to the fetus.
Q: Is NEBIRITE 5 TABLET safe for children?
A: Safety and effectiveness in pediatric patients have not been established. Pediatric studies in ages newborn to 18 years old have not been conducted because of incomplete characterization of developmental toxicity and possible adverse effects on long-term fertility.
Q: Who should not use NEBIRITE 5 TABLET?
A: NEBIRITE 5 TABLET is not recommended for use if you have serious circulation problems in arms or legs, unmanaged pheochromocytoma (tumor of the adrenal gland), or have diabetic ketoacidosis, liver disease, lung disease such as asthma or wheezing, heart diseases such as low blood pressure, a very slow heartbeat, heart rhythm problems, or heart failure, or are allergic to Nebivolol.
Q: What precautions must be taken while using NEBIRITE 5 TABLET?
A: Before taking NEBIRITE 5 TABLET, inform your doctor if you have diabetes, an overactive thyroid gland, have planned surgery and require anesthesia, or have lactose intolerance, severe kidney disease, patients who are undergoing dialysis, Prinz metal angina, unmanaged chronic heart failure, and first-degree heart block.
References
1. KD. Tripathi. Antiadrenergic Drugs and Drugs for Glaucoma. Essentials of medical pharmacology. Seventh edition. 2013. Page – 149.
2. Shivani Priyadarshni, Bryan H. Curry. Nebivolol. NIH. National Library of Medicine, National Center for Biotechnology Information. Nov 2021. [Accessed on 24th August 2024] click here
3. Glenmark Pharmaceuticals Europe Limited. Electronic Medicines Compendium (EMC). [Revised in July 2019] [Accessed on 24th August 2024] click here
4. Glenmark Pharmaceuticals Europe Limited. Electronic Medicines Compendium (EMC). [Revised in Dec 2018] [Accessed on 24th August 2024] click here
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