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Introduction About NEBICARD 2.5MG TABLET
Nebicard 2.5mg Tablet contains the active ingredient nebivolol and is primarily used to help manage high blood pressure (hypertension) and support heart function in adults with mild to moderate chronic heart failure, particularly those aged 70 and older. This medication belongs to a class known as beta-blockers, which help relax blood vessels and slow the heart rate. This action reduces the workload on the heart and supports healthy circulation, which can help lower the risk of serious heart-related events.
Nebicard 2.5mg Tablet is typically recommended for adults diagnosed with hypertension or certain types of heart failure, especially older adults and those with risk factors for heart disease. It may also be considered for those with mild to moderate kidney or liver concerns but should not be used by individuals with severe liver disease, very slow heart rate, advanced heart block, or decompensated heart failure. Always consult your healthcare provider to ensure this medication is suitable for your health needs.
The tablet should be taken by mouth, with or without food, at the same time each day as prescribed by your doctor. Consistency is important for optimal results, and you should not stop taking Nebicard 2.5mg Tablet suddenly without medical advice. Common side effects may include headache, dizziness, fatigue, nausea, or stomach discomfort—contact your doctor if these persist. Regular monitoring of heart rate and blood pressure is recommended during treatment.
Special precautions are necessary for women who are pregnant or breastfeeding, as Nebicard 2.5mg Tablet may pose risks to the baby. Use in these situations should only be considered if clearly needed and under close medical supervision. Patients with diabetes should monitor their blood sugar carefully, as nebivolol may mask certain symptoms of low blood sugar. Always inform your doctor about all medications and supplements you are taking to avoid potential interactions.
Uses Of NEBICARD 2.5MG TABLET
- Management of high blood pressure (hypertension)
- Support for heart function in adults with mild to moderate chronic heart failure
- Helps improve heart function and blood flow by relaxing blood vessels and slowing heart rate
Benefits of NEBICARD 2.5MG TABLET
Nebicard 2.5mg Tablet for high blood pressure
Nebicard 2.5mg Tablet is widely used to assist in the management of high blood pressure, also known as hypertension. Its active ingredient, nebivolol, is a type of beta-blocker that helps relax blood vessels and slow the heart rate. This effect makes it easier for the heart to circulate blood efficiently, which can help maintain healthy blood pressure levels. Nebicard 2.5mg Tablet should be used exactly as directed by your healthcare provider, and it is important to discuss your full medical history and any other medications you are taking before starting this medicine.
How Nebicard 2.5mg Tablet Supports Heart Health
Nebicard 2.5mg Tablet supports heart health in several ways. Unlike many other beta-blockers, nebivolol not only slows the heart rate but also encourages the production of nitric oxide, which helps blood vessels relax and improves blood flow. This combination can reduce the workload on the heart and help keep blood pressure within a healthy range. By supporting better circulation and heart function, Nebicard 2.5mg Tablet may help lower the risk of heart-related complications.
Nebicard 2.5mg Tablet for heart failure
Nebicard 2.5mg Tablet is sometimes prescribed as part of a broader approach to managing mild to moderate chronic heart failure, particularly in older adults. Alongside other standard therapies, it can help maintain heart function and make everyday activities more manageable for those living with heart failure. The way Nebicard 2.5mg Tablet relaxes blood vessels and supports a steady heart rate can contribute to improved well-being and quality of life. Always follow your doctor’s instructions regarding how and when to take this medication for the best results.
How NEBICARD 2.5MG TABLET Works
How Nebicard 2.5mg Tablet lowers blood pressure
Nebicard 2.5mg Tablet contains nebivolol, a selective beta-1 adrenergic receptor blocker. This means it works by reducing the impact of stress hormones on the heart, specifically by blocking beta-1 receptors. As a result, the heart beats more slowly and with less force, which helps to lower both the top (systolic) and bottom (diastolic) numbers of your blood pressure.
In addition to its beta-blocker effects, nebivolol also stimulates the production of nitric oxide in the blood vessel walls. Nitric oxide helps blood vessels relax and widen, which decreases resistance to blood flow and makes it easier for the heart to pump blood throughout the body. This dual action helps Nebicard 2.5mg Tablet effectively lower and maintain healthy blood pressure levels.
Nebivolol mechanism of action for heart failure
For individuals with mild to moderate chronic heart failure, Nebicard 2.5mg Tablet is used as part of a broader management plan. Its main action is to block beta-1 receptors in the heart, which slows the heart rate and reduces the force of heart contractions. This helps to decrease the workload on the heart and support more efficient function.
Nebivolol also has a unique property: it stimulates beta-3 receptors, leading to increased nitric oxide production. Nitric oxide helps blood vessels relax, which lowers resistance and improves blood flow to the heart and other organs. Together, these effects help relieve symptoms of heart failure, support better heart function, and may reduce the risk of heart-related complications.
How Nebicard 2.5mg Tablet supports heart health
Nebicard 2.5mg Tablet supports heart health by combining the effects of a selective beta-blocker with those of a vasodilator. By blocking beta-1 receptors, it helps regulate heart rate and reduce the heart’s workload, which is especially helpful for people with high blood pressure or heart failure.
The vasodilating action, achieved through increased nitric oxide production, further benefits heart health by relaxing blood vessels and improving circulation. This not only helps to lower blood pressure but also ensures that the heart and other organs receive an adequate supply of blood. When used as prescribed, Nebicard 2.5mg Tablet can help maintain stable heart function, reduce the risk of serious heart events, and support overall cardiovascular well-being.
How to use NEBICARD 2.5MG TABLET
Recommended Dosage of Nebicard 2.5mg Tablet
- The usual starting dose for most adults is higher, but Nebicard 2.5mg Tablet is prescribed when a lower initial dose is needed.
- Your doctor may start with 2.5 mg once daily for certain patients, especially if you have other health conditions.
- Your doctor will adjust the dose as needed based on your response and overall health.
How and When to Take Nebicard 2.5mg Tablet
- Take Nebicard 2.5mg Tablet by mouth, with or without food, as directed by your doctor.
- Try to take your tablet at the same time every day to help you remember.
- Swallow the tablet whole with a glass of water.
- Do not stop taking Nebicard 2.5mg Tablet suddenly without talking to your doctor.
Special Instructions for Patients with Kidney or Liver Issues
- If you have severe kidney problems, your doctor may start you on 2.5 mg once daily.
- If you have moderate liver impairment, the starting dose is also usually 2.5 mg once daily.
- Nebicard 2.5mg Tablet is not recommended for people with severe liver disease.
- Your doctor may monitor you more closely if you have kidney or liver issues.
Nebicard 2.5mg Tablet initial dose and titration
- The initial dose is often 2.5 mg once daily for people who may be more sensitive to the medicine or who have kidney or liver problems.
- Your doctor may increase your dose slowly if needed, usually waiting at least two weeks between changes.
- Do not change your dose without your doctor’s advice.
How Long Should You Take Nebicard 2.5mg Tablet?
- Take Nebicard 2.5mg Tablet for as long as your doctor prescribes.
- Do not stop taking the medicine without first talking to your doctor, even if you feel well.
- Regular check-ups with your doctor are important to monitor your health.
What if I forgot to take NEBICARD 2.5MG TABLET
If you miss a dose of Nebicard 2.5mg Tablet, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one, as this can increase the risk of side effects. Maintaining a consistent daily routine helps ensure the medication works effectively. If you are unsure or have missed multiple doses, consult your healthcare provider for guidance.
Overdose
Taking more Nebicard 2.5mg Tablets than prescribed can lead to an overdose, which may cause symptoms such as severe dizziness, very slow or irregular heartbeat, fainting, difficulty breathing, or extreme fatigue. If an overdose is suspected, seek immediate medical attention or contact emergency services. It is important to keep the medication out of reach of children and to follow the prescribed dosage carefully to avoid accidental overdose. In case of any unusual symptoms after taking the medication, contact your healthcare provider promptly.
Side Effects Of NEBICARD 2.5MG TABLET
Common Side Effects of NEBICARD 2.5MG TABLET:
- dizziness
- tiredness
- diarrhoea, constipation
When to Seek Medical Attention?
Stop taking NEBICARD 2.5MG TABLET and contact your doctor immediately if you experience any of the following side effects:
- severe allergic reactions, with generalized skin eruptions (hypersensitive reactions)
- rapid onset of swelling around the lips, eyes, or tongue with sudden difficulties in breathing (angioedema)
- skin rash involving pale red, raised, itchy bumps of allergic or non-allergic causes
- breathlessness, such as in asthma, tightening of the chest, difficulty breathing, or wheezing
How To Manage Side Effects

Constipation
- Increase fiber intake: Eat more fruits, vegetables, whole grains, and legumes to promote regular bowel movements.
- Stay hydrated: Drink plenty of water throughout the day to help soften stools.
- Exercise regularly: Physical activity can help stimulate bowel function.
- Consider gentle laxatives if needed: Use only as recommended by your doctor or pharmacist if lifestyle changes are not effective.
- Consult your doctor: If constipation persists or is severe, seek medical advice.

Diarrhea
- Stay hydrated: Drink plenty of water and oral rehydration solutions to replace lost fluids and electrolytes.
- Avoid irritating foods: Limit intake of spicy, fatty, or dairy-rich foods until symptoms improve.
- Eat bland foods: Choose simple foods like bananas, rice, applesauce, and toast (BRAT diet) to help settle your stomach.
- Consult your doctor: If diarrhoea is severe, persistent, or accompanied by fever, seek medical advice.

Dizziness Or Drowsiness
- Move slowly: When getting up from sitting or lying down, rise slowly to prevent lightheadedness or falls.
- Avoid sudden movements: Take your time when changing positions to reduce the risk of dizziness.
- Stay hydrated: Drink enough fluids to help maintain blood pressure.
- Avoid alcohol: Alcohol can worsen dizziness.
- Consult your doctor: If dizziness is severe, persistent, or accompanied by fainting, seek medical attention
Warning & Precautions

Pregnancy
Consult your doctorNo studies of this medicine were conducted in pregnant women. Use of NEBICARD 2.5MG TABLET during pregnancy only if the potential benefit justifies the potential risk to the fetus.

Breastfeeding
Consult your doctorIt is not known whether this medicine is excreted in human milk. NEBICARD 2.5MG TABLET is not recommended during nursing.

Driving and Using Machines
Use with CautionDo not drive or operate any machines if you experience dizziness or fatigue after taking NEBICARD 2.5MG TABLET.

Kidney
Use with CautionNEBICARD 2.5MG TABLET should be used with caution in patients with severe kidney disease or patients who are undergoing dialysis.

Liver
ContraindicatedNEBICARD 2.5MG TABLET is not recommended for use in patients with liver disease.

Allergy
ContraindicatedDo not take NEBICARD 2.5MG TABLET if you are allergic to Nebivolol or to any other ingredients of this medicine.

Lungs
ContraindicatedNEBICARD 2.5MG TABLET is not recommended for use in patients with lung disease such as asthma or wheezing.

Heart Disease
Consult your doctorNEBICARD 2.5MG TABLET is not recommended in patients having heart diseases such as low blood pressure, very slow heartbeat, heart rhythm problems, or heart failure. It should be used with caution in patients having Prinz metal angina, unmanaged chronic heart failure, and first-degree heart block.

Use In Pediatrics
Consult your doctorSafety and effectiveness in pediatric patients have not been established. Pediatric studies in ages newborn to 18 years old have not been conducted because of incomplete characterization of developmental toxicity and possible adverse effects on long-term fertility.

Use In Geriatrics
Consult your doctorNo overall differences in efficacy or in the incidence of adverse events were observed between older and younger patients.
Other Warnings for NEBICARD 2.5MG TABLET
Before taking NEBICARD 2.5MG TABLET, inform your doctor if you:
- have diabetes
- have an overactive thyroid gland
- have planned surgery and require anesthesia
- have lactose intolerance
Who should not take [GBNKEYWORD
It is not recommended for use if you:
- have serious circulation problems in arms or legs
- have unmanaged pheochromocytoma (tumor of the adrenal gland)
- have diabetic ketoacidosis
Safety Advice
Monitoring and Regular Check-ups with Nebicard 2.5mg Tablet
- Regular monitoring of your blood pressure and heart rate is essential while taking Nebicard 2.5mg Tablet.
- Your doctor may schedule periodic check-ups to assess your response to the medication and to monitor for any side effects.
- If you have diabetes, monitor your blood sugar levels closely, as Nebicard 2.5mg Tablet may mask symptoms of low blood sugar.
- Report any new or worsening symptoms, such as shortness of breath, swelling in your legs, or unusual fatigue, to your doctor promptly.
- Keep all follow-up appointments and discuss any concerns or side effects with your healthcare provider.
Nebicard 2.5mg Tablet surgery precautions
- If you are scheduled for any surgery or medical procedure, inform your surgeon or dentist that you are taking Nebicard 2.5mg Tablet.
- Your doctor may advise you to stop taking Nebicard 2.5mg Tablet several days before surgery, depending on your condition and the type of procedure.
- Do not stop or change your medication without your doctor’s instructions, as sudden discontinuation can be dangerous for your heart.
- Your healthcare team will monitor your blood pressure and heart function closely before, during, and after surgery to ensure your safety.
Diet and Lifestyle Advice
Eating a balanced diet and making healthy lifestyle choices can help you get the best results from Nebicard 2.5mg Tablet and support your heart health.
Low-Salt Diet
Cut down on salty foods and avoid adding extra salt to your meals. Processed foods, canned soups, salty snacks, and fast foods are often high in sodium, so it’s best to limit these. Reducing salt intake helps lower blood pressure and makes your medication more effective.
Low-Fat Diet
Choose lean proteins, low-fat dairy products, and healthy fats from nuts, seeds, and olive oil. Try to avoid fried foods, pastries, and fatty meats, which contain saturated and trans fats that can harm your heart.
Heart-Healthy Foods
Make sure to include plenty of whole grains, fruits, and vegetables in your daily meals. These foods are packed with fiber, vitamins, and minerals that help keep your heart strong and healthy.
Regular Physical Activity
Stay active by doing exercises like walking, swimming, or cycling for at least 30 minutes most days of the week. Regular physical activity helps lower blood pressure, improves circulation, and helps you maintain a healthy weight.
Weight Management
Aim to keep a healthy weight by eating well and staying active. Losing extra weight can help lower your blood pressure and reduce the strain on your heart.
Avoid Alcohol and Smoking
It’s best to avoid alcohol while taking Nebicard 2.5mg Tablet, as it can cause dizziness and lower your blood pressure too much. If you smoke, try to quit—smoking increases your risk of heart disease and can make your medication less effective.
Stress Management
Find ways to manage stress, such as practicing meditation, yoga, or deep breathing exercises. Lowering stress levels can help reduce blood pressure and improve your overall well-being.
Regular Monitoring
Keep track of your blood pressure and overall health as advised by your doctor. Attend all your medical check-ups to make sure your treatment is working well.
Nebicard 2.5mg Tablet vs other beta-blockers
Feature |
Nebicard (Nebivolol) |
Metoprolol |
Propranolol |
Carvedilol |
Type |
Beta-1 selective with vasodilation |
Beta-1 selective |
Non-selective |
Non-selective with alpha-1 blockade |
Vasodilation |
Yes (NO-mediated) |
No |
No |
Yes (via alpha-1 blockade) |
Primary Use |
Hypertension, heart failure |
Hypertension, angina, heart failure |
Anxiety, migraine, hypertension |
Heart failure, hypertension |
Effect on Heart Rate |
Moderate |
Strong |
Strong |
Strong |
Metabolic Effects |
Neutral |
May worsen lipids or glucose |
May worsen lipids or glucose |
Neutral or mild impact |
CNS Side Effects |
Low |
Moderate |
High (crosses blood-brain barrier) |
Moderate |
Asthma/COPD Suitability |
Relatively safer |
Caution advised |
Not recommended |
Not recommended |
Dosing Frequency |
Once daily |
Once or twice daily |
Usually twice daily |
Twice daily |
Special Benefit |
Improves endothelial function, suitable for elderly |
Effective post-MI and in heart failure |
Useful in anxiety, tremors, migraine |
Effective in heart failure with hypertension |
Drug - Drug interaction
Nebicard 2.5mg Tablet (nebivolol) can interact with many other medications, which may change how it works or increase the risk of side effects. It is important to inform your doctor about all prescription and over-the-counter medicines, vitamins, supplements, and herbal products you are using before starting nebivolol. Your doctor can help manage these interactions to keep you safe and ensure the best results from your treatment.
1. Antidepressants (such as fluoxetine, paroxetine)
Interaction: When taken with nebivolol, certain antidepressants can increase the level of nebivolol in your body. This may raise the risk of side effects like a very slow heart rate or low blood pressure.
Management: Your doctor may adjust your nebivolol dose or choose a different medication. Regular monitoring of your heart rate and blood pressure will help keep you safe.
2. Heart Medications (such as digoxin, verapamil, diltiazem, disopyramide)
Interaction: Taking nebivolol with other heart medicines can cause your heart rate to become very slow or increase the risk of irregular heart rhythms.
Management: Your doctor will monitor your heart function closely and may need to adjust your medications.
3. Irregular Heart Rhythm Drugs (such as quinidine, propafenone)
Interaction: These medicines can increase the amount of nebivolol in your body, which may lead to more side effects.
Management: Your doctor may lower your nebivolol dose or consider alternative treatments.
4. Other Beta-Blockers
Interaction: Using nebivolol with other beta-blockers can cause excessive slowing of the heart and very low blood pressure.
Management: Combining beta-blockers is generally not recommended. If needed, your doctor will monitor you very closely.
5. Medications for Asthma or COPD (such as theophylline, aminophylline)
Interaction: Nebivolol may reduce the effectiveness of these medicines or worsen breathing problems in people with asthma or COPD.
Management: These medicines should generally not be used together. If they must be used, your doctor will watch for symptoms like breathlessness or dizziness.
6. Medications for High Blood Pressure or Diabetes
Interaction: Nebivolol can interact with other blood pressure or diabetes medicines, increasing the risk of low blood pressure or masking symptoms of low blood sugar.
Management: Your doctor will monitor your blood pressure and blood sugar and may adjust your medications as needed.
Drug - Food interaction
Most foods are safe to eat with Nebicard 2.5mg Tablet, but some foods, drinks, and supplements might interact with it and affect how it works in your body. Knowing about these possible interactions helps you use your medication safely and get the best results. Always talk to your healthcare provider before making changes to your diet or supplement routine while taking Nebicard 2.5mg Tablet.
1. Alcohol
Interaction: Drinking alcohol while taking Nebicard 2.5mg Tablet may increase the risk of side effects such as dizziness, lightheadedness or fainting. Both alcohol and nebivolol can lower blood pressure and their combined effect can be stronger than expected.
Management: Avoid or limit alcohol. If you do drink, do so in moderation and watch for symptoms like dizziness or weakness.
2. Caffeine
Interaction: Caffeine in coffee, tea, energy drinks, and some sodas may reduce the effectiveness of nebivolol or cause it to stay in your body longer.
Management: Limit your caffeine intake. If you notice changes in how you feel after consuming caffeine, talk to your healthcare provider.
3. Potassium-Rich Foods
Interaction: Eating large amounts of potassium-rich foods like bananas, oranges, potatoes, or spinach could potentially raise your potassium levels, especially if you have kidney problems.
Management: Maintain a balanced diet and avoid excessive intake of potassium-rich foods unless your doctor advises otherwise.
Synopsis
Drug |
: |
Nebivolol |
Pharmacological Category |
: |
Selective Beta-blockers |
Therapeutic Indication |
: |
Hypertension, Mild to moderate chronic heart failure |
Dosage Forms |
: |
Tablet |
More Information
Storage
- Keep Nebicard 2.5mg Tablet out of the sight and reach of children
- Store Nebicard 2.5mg Tablet below 30°C
FAQs About NEBICARD 2.5MG TABLET
Q: What is Nebicard 2.5mg Tablet used for?
A: Nebicard 2.5mg Tablet is used to treat high blood pressure and mild to moderate heart failure. It helps relax blood vessels and slow the heart rate, improving heart function. It is part of a comprehensive plan for cardiovascular health.
Q: How does Nebicard 2.5mg Tablet work?
A: Nebicard 2.5mg Tablet works by blocking adrenaline effects on the heart and blood vessels. It also stimulates nitric oxide production, helping blood vessels widen. This dual action lowers blood pressure and eases heart workload.
Q: Who should not take Nebicard 2.5mg Tablet?
A: People with severe heart failure, very slow heartbeats, severe heart block, or allergies to nebivolol should avoid it. Those with severe liver disease or certain lung conditions like asthma should also not take it. Always inform your doctor of your medical history.
Q: Can I drink alcohol while taking Nebicard 2.5mg Tablet?
A: It is best to avoid or limit alcohol while taking this medication. Alcohol can increase dizziness and lower blood pressure too much. If you do drink, do so in moderation.
Q: Can I take Nebicard 2.5mg Tablet during pregnancy?
A: Nebicard 2.5mg Tablet is generally not recommended during pregnancy. It may affect the baby, especially in later stages. Consult your doctor before starting or stopping this medication.
Q: How long does it take for Nebicard 2.5mg Tablet to work?
A: It may start lowering blood pressure within hours, but full effects can take days to weeks. Consistent use is important for best results. Your doctor may adjust your dose as needed.
Q: Can Nebicard 2.5mg Tablet be taken with other blood pressure medications?
A: It can be taken with other blood pressure medications if prescribed by your doctor. Combining certain medications may increase side effects. Always inform your doctor about all medicines you take.
Q: Can Nebicard 2.5mg Tablet be used in elderly patients?
A: It can be used in elderly patients, but they may be more sensitive to its effects. Doctors may start with a lower dose and monitor closely. Regular check-ups are important.
Q: Can I stop taking Nebicard 2.5mg Tablet if my blood pressure is normal?
A: Do not stop taking Nebicard 2.5mg Tablet without consulting your doctor. Stopping suddenly can cause blood pressure to rise again. Your doctor will guide you on managing your medication.
Q: Can Nebicard 2.5mg Tablet be taken with diabetes medications?
A: It can be taken with diabetes medications, but may mask low blood sugar symptoms. Monitor your blood sugar closely. Inform your doctor about all medications you are taking.
Q: What lifestyle changes should I make while taking Nebicard 2.5mg Tablet?
A: Eat a low-salt, low-fat diet and exercise regularly. Maintain a healthy weight and avoid smoking and excessive alcohol. These changes support your heart health and medication effectiveness.
Q: How often should I monitor my blood pressure while taking Nebicard 2.5mg Tablet?
A: Monitor your blood pressure as advised by your doctor. This may be daily, weekly, or at regular intervals. Keep a record and share it with your healthcare provider.
Q: What should I do if I have kidney or liver problems and need to take Nebicard 2.5mg Tablet?
A: Inform your doctor if you have kidney or liver issues. Your doctor may start with a lower dose and monitor you closely. Severe liver disease is a contraindication for use.
Q: Can Nebicard 2.5mg Tablet be taken before surgery?
A: Inform your surgeon if you are taking Nebicard 2.5mg Tablet. Your doctor may advise you to stop it before surgery. Do not stop or change your medication without medical advice.
References
1. KD. Tripathi. Antiadrenergic Drugs and Drugs for Glaucoma. Essentials of medical pharmacology. Seventh edition. 2013. Page – 149.
2. Shivani Priyadarshni, Bryan H. Curry. Nebivolol. NIH. National Library of Medicine, National Center for Biotechnology Information. Nov 2021. [Accessed on 25th June 2025]
3. Glenmark Pharmaceuticals Europe Limited. Electronic Medicines Compendium (EMC). [Revised in July 2019] [Accessed on 25th June 2025]
4. Glenmark Pharmaceuticals Europe Limited. Electronic Medicines Compendium (EMC). [Revised in Dec 2018] [Accessed on 25th June 2025]