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Aristo Pharmaceuticals Pvt Ltd

NEBI T Tablet 10's

Hypertension
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    Introduction About NEBI T TABLET

    NEBI T TABLET is a combination of Nebivolol and Telmisartan which belongs to the group of medicines called Antihypertensive agents. It is used to manage hypertension (high blood pressure) when management with single agents is not effective. Hypertension (also known as high blood pressure) is a medical condition in which the force of the blood exerted against the walls of the artery remains very high and as a result it may lead to severe damage to the blood vessels supplying several vital organs, such as heart, kidney or brain. If left unmanaged, it may cause serious complications such as heart attack, heart failure, stroke or even blindness.

    By lowering blood pressure, NEBI T TABLET can also reduce the risk of heart attack (myocardial infarction) or stroke. During management with NEBI T TABLET your doctor will constantly monitor kidney functions, blood pressure, electrolyte levels and blood sugar levels to avoid the risk of unwanted side effects. Before taking NEBI T TABLET inform your doctor if you have any heart, liver or kidney problems. You must also inform your doctor if you have diabetes, low blood pressure or are severely dehydrated due to excessive vomiting or diarrhea.

    NEBI T TABLET is not suitable for use in pregnant or breastfeeding women as it may cause serious harm to the growing baby. Stop taking NEBI T TABLET and inform your doctor immediately if you become pregnant while undergoing therapy with NEBI T TABLET. The most common side effects of taking NEBI T TABLET are low blood pressure, headache, dizziness, high blood potassium levels, pins and needles, muscle pain, diarrhoea, constipation and erectile dysfunction. Contact your doctor if any of these side effect worsens.

    Uses Of NEBI T TABLET

    It is used to:

    • manage hypertension (high blood pressure)
    • manage the risk of heart attack or stroke

    How NEBI T TABLET Works

    NEBI T TABLET is an antihypertensive medicine which relaxes your blood vessels and improves blood flow across them. It also slows down the heart rate and reduces the force of contraction of heart muscles. As a result, it reduces the strain on the heart, improves blood flow across the blood vessels and makes the heart to pump blood more smoothly and efficiently with less pressure.

    How to use NEBI T TABLET

    Take NEBI T TABLET as directed by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Try to take NEBI T TABLET at the same time each day. NEBI T TABLET can be taken with or without food. Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and health condition.

    Side Effects Of NEBI T TABLET

    Common

    • headache
    • dizziness
    • tiredness
    • tingling sensation or unusual itching in the body
    • diarrhoea
    • constipation
    • nausea
    • shortness of breath
    • swollen hands or feet
    • low blood pressure

    Uncommon

    • urinary tract infections
    • sore throat, sinus inflammation, common cold, cough
    • anaemia
    • high blood potassium levels
    • lack of sleep
    • nightmares
    • vertigo
    • depression
    • feeling faint
    • low blood pressure causing dizziness while standing up
    • stomach pain
    • diarrhoea
    • flatulence
    • vomiting
    • increased sweating
    • back pain
    • muscle spasm or pain
    • abnormal vision
    • impotency (problems in reaching orgasm)
    • skin rash or itching

    Rare

    • low platelet count in blood
    • low blood sugar levels
    • dry mouth
    • changes in taste
    • increased levels of uric acid in blood
    • liver problems

    Stop taking NEBI T TABLET and contact your doctor immediately if you experience any of the following side effects:

    • severe allergic reactions (such as skin rash, itching, swelling of the face, lips, mouth or throat which can lead to difficulty in breathing or swallowing)
    • sepsis (blood infection)

    How To Manage Side Effects

    Dizziness Or Drowsiness

    Try to rest and relax. Get enough sleep. Avoid driving or operating any tools or machines completely while you are feeling dizzy. Do not consume excessive alcohol, as it could aggravate your dizziness. Consult your doctor if your dizziness worsens.

    Headache

    Rest and relax. Keep yourself hydrated by drinking plenty of fluids such as water or electrolytes. Applying a pain-relieving balm on your forehead can be beneficial. Do not consume excessive alcohol, as it could aggravate your headache. Consult your doctor if your headache worsens.

    Nausea And Vomiting

    Take NEBI T TABLET with or just after a meal or a snack. Stick to simple meals. Avoid eating rich or spicy food. Consult your doctor if your nausea worsens.

    Warning & Precautions

    Pregnancy

    Contraindicated

    NEBI T TABLET is not recommended for use in pregnant women as it may cause serious harm to the growing fetus. Therefore, inform your doctor before taking NEBI T TABLET if you are pregnant, think you may be pregnant or planning to have a baby. If you become pregnant while undergoing therapy with NEBI T TABLET, stop taking it and consult your doctor immediately.

    Breastfeeding

    Contraindicated

    NEBI T TABLET is not recommended for use in breastfeeding women. Therefore, consult your doctor before taking it.

    Driving and Using Machines

    Use with Caution

    Do not drive or handle any heavy tools or machines if your ability is affected by NEBI T TABLET.

    Alcohol

    Consult your doctor

    Avoid consumption of alcohol while taking NEBI T TABLET as it might make you feel dizzier and drowsier.

    Kidney

    Consult your doctor

    NEBI T TABLET is not recommended for use in patients with severe kidney problems. It should be used with caution in patients with other kidney problems (such as kidney transplant, narrowing of renal arteries). Therefore, consult your doctor before taking it.

    Liver

    Consult your doctor

    NEBI T TABLET is not recommended for use in patients with severe liver impairment (such as cholestasis, jaundice, biliary obstruction). It should be used with caution in patients with mild to moderate liver problems. Therefore, consult your doctor before taking it.

    Allergy

    Contraindicated

    Do not take NEBI T TABLET if you are allergic to Nebivolol or Telmisartan or any other ingredients of this medicine.

    Lungs

    Consult your doctor

    NEBI T TABLET is not recommended for use in patients with asthma or other breathing problems. It should be used with caution in patients with chronic bronchitis (inflammation of the airways). Therefore, consult your doctor before taking the medicine.

    Heart Disease

    Consult your doctor

    NEBI T TABLET is not recommended for use in patients with slow heartbeat, serious heart rhythm problems or recent heart failure. It should be used with caution in patients having angina (chest pain) or heart block. Therefore, consult your doctor before taking it.

    Use In Pediatrics

    Contraindicated

    NEBI T TABLET is not recommended for use in children and adolescents (aged below 18 years). Therefore, consult your doctor for advice.

    Use In Geriatrics

    Use with Caution

    NEBI T TABLET should be used with caution in the elderly patients. Therefore, consult your doctor before taking it.

    Others

    NEBI T TABLET is not recommended for use if you:

    • have low blood pressure
    • have poor blood circulation in the arms and legs
    • have metabolic acidosis
    • have unmanaged phaeochromocytoma
    • have diabetes related kidney problems

    Before taking NEBI T TABLET inform your doctor if you:

    • have a slow heartbeat with shortness of breath and dizziness
    • have Raynaud’s disease
    • have leg pain, tension or weakness
    • have diabetes
    • have overactivity of thyroid gland
    • have psoriasis
    • are going to undergo an operation
    • have primary hyperaldosteronism
    • are severely dehydrated (due to diarrhea, vomiting or excess sweating)
    • are on a low-salt diet

    Interactions

    A. Drug-Drug interactions:

    Before taking NEBI T TABLET inform to your doctor, if you are taking any of the following medicines such as:

    • calcium channel blockers (used to manage heart problems) such as verapamil, diltiazem, amlodipine, felodipine, lacidipine, nifedipine, nicardipine, nimodipine and nitrendipine
    • other medicines used to manage high blood pressure (such as clonidine, guanfacine, moxonidine, methyldopa, rilmenidine, aliskiren, captopril, enalapril, ramipril, losartan, valsartan)
    • medicines used to manage uneven heartbeat (such as digoxin, quinidine, hydroquinidine, amiodarone, cibenzoline, ­ecainide, disopyramide, lidocaine, mexiletine and propafenone)
    • medicines used to manage anxiety (such as phenobarbital, chlorpromazine)
    • medicines used to manage depression (such as lithium, amitriptyline, trazodone, paroxetine, fl­uoxetine and thioridiazine)
    • medicines used to manage asthma (such as salbutamol, salmeterol, budesonide)
    • medications used to manage cough and cold (such as pseudoephedrine)
    • medicines used to manage glaucoma (such as timolol, pindolol)
    • medicines used to manage diabetes (such as insulin, metformin, gliclazide, glibenclamide)
    • anaesthetics (used to cause numbness or loss of sensation) such as lidocaine, sevoflurane, halothane
    • cimetidine (a medicine used to manage stomach ulcers)
    • antacids (medicines used to neutralise stomach acid) such as aluminium hydroxide, magaldrate
    • medicines used for pain and inflammation (such as aspirin, ibuprofen, diclofenac)
    • baclofen (a medicine used for relaxing muscles)
    • amifostine (a kidney protectant used along with chemotherapeutic agents)
    • potassium supplements or potassium-sparing diuretics such as spironolactone, triamterene or amiloride (used to retain or increase potassium levels in the body)
    • heparin (a medicine used to manage or manage blood clots)
    • trimethoprim (a medicine used to manage bacterial infections)
    • medicines used to suppress immune functions (such as tacrolimus, cyclosporin)
    • narcotic drugs (used for pain relief) such as morphine, fentanyl, pethidine

    Overdosage:

    If you or anyone else accidentally took excessive amount of this medicine, consult your doctor immediately or visit the nearby hospital straight away. Symptoms of overdosage might include low blood pressure, fast or slow heart rate, dizziness, kidney problems and shortness of breath.

    Synopsis

    Drug :   Nebivolol, Telmisartan
    Pharmacological Category :   Beta-Blockers, Angiotensin-II receptor blockers
    Therapeutic Indication :   Hypertension          
    Dosage Forms :   Tablet

    More Information

    Storage

    • Keep NEBI T TABLET out of reach to children
    • Store NEBI T TABLET at room temperature

    FAQs About NEBI T TABLET

    Q: What are the uses of NEBI T TABLET?

    A: NEBI T TABLET is used to manage hypertension. It can also be used to manage the risk of heart attack or stroke.

    Q: What type of a medicine is NEBI T TABLET?

    A: NEBI T TABLET is an antihypertensive medicine. It relaxes your blood vessels and improves blood flow across them. It also slows down the heart rate and reduces the force of contraction of heart muscles. As a result, it reduces the strain on the heart, improves blood flow across the blood vessels and makes the heart to pump blood more smoothly and efficiently with less pressure.

    Q: What happens when I stop taking NEBI T TABLET?

    A: Do not stop taking NEBI T TABLET without consulting your doctor as your blood pressure may raise once again. Make sure to take NEBI T TABLET for the stipulated duration recommended by your doctor to achieve maximum results.

    Q: What is the best time to take NEBI T TABLET?

    A: NEBI T TABLET can be taken with or without meals. Your doctor will decide the best time for you to take NEBI T TABLET based on your age, body weight and disease condition.

    Q: What to do if I forgot to take a dose of NEBI T TABLET?

    A: If you forgot to take a dose of NEBI T TABLET, take it as soon as you remember. However, if it is time for the next dose of NEBI T TABLET, skip the missed dose and take the next one regularly. Do not take a double dose of NEBI T TABLET to compensate the missed ones.

    Q: What precautions should be followed while taking NEBI T TABLET?

    A: Before taking NEBI T TABLET, inform your doctor if you have any heart, liver or kidney problems. You must also inform your doctor if you have diabetes, low blood pressure volume or are severely dehydrated. Stop taking NEBI T TABLET and consult your doctor immediately if you become pregnant. Regularly visit your doctor and take all the necessary blood test recommended by your doctor without fail.

    Q: Can I consume alcohol while taking NEBI T TABLET?

    A: Avoid consumption of alcohol while taking NEBI T TABLET as it might make you feel dizzier and drowsier.

    Q: What happens if I accidentally take more NEBI T TABLET?

    A: If you or anyone else accidentally took excessive amount of this medicine, consult your doctor immediately or visit the nearby hospital straight away. Symptoms of overdosage might include low blood pressure, fast or slow heart rate, dizziness, kidney problems and shortness of breath.

    Q: Can I take NEBI T TABLET daily?

    A: Take NEBI T TABLET as advised by your physician. Your doctor will evaluate your health condition and suggests whether can you take NEBI T TABLET every day or not.

    Q: Is NEBI T TABLET safe to use in diabetic patients?

    A: NEBI T TABLET may alter the blood sugar levels in the body. Therefore, it is necessary to inform your doctor if you have diabetes before taking NEBI T TABLET as a precaution. Your doctor will closely monitor you blood sugar levels to avoid the risk of side effects.

    Q: What are the common side effects of NEBI T TABLET?

    A: The most common side effects of taking NEBI T TABLET are low blood pressure, headache, dizziness, high blood potassium levels, pins and needles, muscle pain, diarrhoea, constipation and erectile dysfunction. Contact your doctor if any of these side effect worsens.

    Q: Can I stop taking NEBI T TABLET once my symptoms subside?

    A: No. Do not stop taking NEBI T TABLET without consulting your doctor. As hypertension is a chronic condition, long term management may be necessary to control its symptoms. Therefore, take NEBI T TABLET as advised by your doctor for the stipulated duration. Premature discontinuation of therapy may increase your blood pressure once again.

    Q: Can NEBI T TABLET be taken during pregnancy?

    A: NEBI T TABLET is not recommended for use in pregnant women as it may cause serious harm to the growing fetus. Therefore, inform your doctor before taking NEBI T TABLET if you are pregnant, think you may be pregnant or planning to have a baby. If you become pregnant while undergoing therapy with NEBI T TABLET, stop taking it and consult your doctor immediately.

    Q: Is NEBI T TABLET safe to use in kidney disease?

    A: NEBI T TABLET is not recommended for use in patients with severe kidney problems. It should be used with caution in patients with other kidney problems (such as kidney transplant, narrowing of renal arteries). Your doctor will access your health condition and suggest a suitable dose for you. Therefore, it is important to inform your doctor if you have any kidney problems before taking NEBI T TABLET as a precaution.

    Q: Can the use of NEBI T TABLET affect the liver?

    A: Yes. NEBI T TABLET may affect the way your liver work. It can elevate the levels of certain liver enzymes in your body. Therefore, it is strictly not recommended for use in patients with severe liver diseases. It should be used with caution in patients with other minor liver problems. Consult your doctor before taking it.

    References

    1. KD. Tripathi. Antiadrenergic Drugs (Adrenergic Receptor Antagonists) and Drugs for Glaucoma & Drugs Affecting Renin-Angiotensin System And Plasma Kinin. Essentials of medical pharmacology. Seventh edition. 2013. Page-149 & 507.

    2. Cockcroft John. A review of the safety and efficacy of nebivolol in the mildly hypertensive patient. NIH. National Library of Medicine. National Center for Biotechnology Information. PMC. PubMed Central. December 2007. [Accessed on 30th December 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2350132/

    3. Philippe Gosse. A Review of Telmisartan in the Treatment of Hypertension: Blood Pressure Control in the Early Morning Hours. NIH. National Library of Medicine. National Center for Biotechnology Information. PMC. PubMed Central. September 2006. [Accessed on 30th December 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1993985/

    4. Accord Healthcare Limited. Electronic Medicines Compendium (EMC). [Revised in April 2022] [Accessed on 30th December 2022] https://www.medicines.org.uk/emc/files/pil.5828.pdf

    5. Actavis Ltd. Health Products Regulatory Authority (HPRA). [Revised in July 2021] [Accessed on 30th December 2022] http://www.hpra.ie/img/uploaded/swedocuments/8c0fc811-cf88-4bd5-818e-609e07fe1190.pdf

    6. Torrent Pharmaceuticals Ltd. Nebicart T. [Revised in February 2022] [Accessed on 30th December 2022] https://www.torrentian.com/pisheet/Upload/PI_Sheet/2751.pdf

    Useful Diagnostic Tests

    • Kidney Function Test

    Author Details

    Written By Dr. Janet.C - Pharm.D
    Reviewed For Accuracy By Dr. Thamada Manikanta Praveen - MBBS, MD (General Medicine)
    Last updated on 20 Sep 2024 | 10:06 AM(IST)
    Lab updated