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Introduction About MONOCEF O CV 100/62.5 ORAL SUSPENSION

MONOCEF O CV 100/62.5 ORAL SUSPENSION is a combination of Cefpodoxime and Clavulanic acid which belongs to the group of medicines called Cephalosporins and Beta-lactamase inhibitors, respectively. MONOCEF O CV 100/62.5 ORAL SUSPENSION is used in children to manage mild to moderate infections such as otitis media (middle ear infection), nose & throat infections, respiratory tract infection, urinary tract infection, reproductive tract infection, and skin infection.

MONOCEF O CV 100/62.5 ORAL SUSPENSION is not recommended for use in children allergic to Cefpodoxime, Clavulanic acid, and/or other cephalosporin group of antibiotics. It is also not recommended for use in children suffering from galactose intolerance, Lapp lactase deficiency (lactose intolerance), and glucose-galactose malabsorption (condition marked by body’s inability to absorb glucose and galactose sugars).

Before administering MONOCEF O CV 100/62.5 ORAL SUSPENSION, inform your doctor if the child has previous history of hypersensitivity reactions to medicines such as cefpodoxime, other cephalosporins, penicillin, and/or have kidney problems (such as mild/moderate/severe renal impairment), and liver problems (such as hepatic insufficiency/impairment).

MONOCEF O CV 100/62.5 ORAL SUSPENSION is not recommended for use in pregnant and breastfeeding women since it is used only in children (aged below 12 years). It is also not recommended for use in elderly patients.

The most common side effects of administering MONOCEF O CV 100/62.5 ORAL SUSPENSION in child are diarrhoea, nausea, vomiting, abdominal pain, headache, vaginal fungal infections, and/or vulvovaginal infections. Consult your doctor if any of these symptoms worsens.

Uses Of MONOCEF O CV 100/62.5 ORAL SUSPENSION

Used in paediatric patients:

To manage mild to moderate infections such as otitis media (middle ear infection), nose & throat infections, respiratory tract infection, urinary tract infection, reproductive tract infection, and skin infection

How MONOCEF O CV 100/62.5 ORAL SUSPENSION Works

MONOCEF O CV 100/62.5 ORAL SUSPENSION helps to manage mild to moderate infections, where Cefpodoxime works by managing the formation of the protective covering of the bacteria which is essential for the survival of bacteria and Clavulanic acid works by reducing the resistance and enhancing the activity of Cefpodoxime against bacteria thus managing the occurrence of infections in affected children.

How to use MONOCEF O CV 100/62.5 ORAL SUSPENSION

Dry Syrup/ Oral Suspension:

Administer MONOCEF O CV 100/62.5 ORAL SUSPENSION as advised by your physician. Shake the dry powder loose and reconstitute the dry powder in required quantity of water before consuming. Your doctor will decide the exact dose and duration of management for your child depending on child’s age, body weight and disease condition.

Syrup:

Administer MONOCEF O CV 100/62.5 ORAL SUSPENSION as advised by your physician. Shake well before use. Your doctor will decide the exact dose and duration of management for your child depending on child’s age, body weight and disease condition.

Side Effects Of MONOCEF O CV 100/62.5 ORAL SUSPENSION

Common

Diarrhoea, vomiting
Diaper rash/fungal skin rash
Non-fungal skin rash

Uncommon

Localized/generalized abdominal pain, abdominal cramp, headache, weakness, fever, fungal infection
Nausea, altered taste, anorexia (eating disorder), dry mouth, oral mucositis, pseudomembranous colitis (inflammation of colon)
Thrombocythemia (low platelet count)
Muscle spasm/pain, hallucination, nervousness, excessive sleepiness
Bleeding from nose, stuffy nose
Fungal infection of skin and nail, red itchy welts, acne, exfoliative dermatitis (severe inflammation of skin), rash

Rare

Stop administering MONOCEF O CV 100/62.5 ORAL SUSPENSION and consult your doctor immediately in case the child experiences:

Signs of allergic reactions such as runny nose, sneezing, breathlessness, itchy skin, and/or raised rash
Seizures

How To Manage Side Effects

Diarrhea

Ask the child to drink lots of fluids such as water or fruit juices so that the child is sufficiently hydrated. Do not administer any medicine to manage the condition on your own. Consult your doctor if the symptom does not improve or becomes worse.

Headache

Ask the child to take rest and drink plenty of fluids. Headaches usually go away after first week of administration of MONOCEF O CV 100/62.5 ORAL SUSPENSION. If it lasts more than a week or becomes severe, then inform your doctor.

Nausea And Vomiting

Have the child take this medicine with or just after a meal or a snack. Let the child stick to simple meals and avoid having rich or spicy food.

Warning & Precautions

Pregnancy

Contraindicated

MONOCEF O CV 100/62.5 ORAL SUSPENSION is not recommended for use in pregnant women as it is used only in children.

Breastfeeding

Contraindicated

MONOCEF O CV 100/62.5 ORAL SUSPENSION is not recommended for use in breastfeeding women as it is used only in children.

Kidney

Use with Caution

MONOCEF O CV 100/62.5 ORAL SUSPENSION should be administered with caution in children with kidney problems such as mild, moderate, and severe renal impairment. Consult your doctor before administering MONOCEF O CV 100/62.5 ORAL SUSPENSION to the child.

Liver

Use with Caution

MONOCEF O CV 100/62.5 ORAL SUSPENSION should be administered with caution in children with liver problems such as hepatic impairment/insufficiency. Consult your doctor before administering MONOCEF O CV 100/62.5 ORAL SUSPENSION to the child.

Allergy

Contraindicated

Use In Pediatrics

Consult your doctor

MONOCEF O CV 100/62.5 ORAL SUSPENSION is recommended for use in children (aged below 12 years). Consult your doctor before administering the medicine to infants (less than 2 years) as safety and efficacy of the medicine have not been established.

Use In Geriatrics

Contraindicated

MONOCEF O CV 100/62.5 ORAL SUSPENSION is not recommended for use in elderly patients as it is used only in children.

Others

MONOCEF O CV 100/62.5 ORAL SUSPENSION is not recommended for use in child, if it has:

Galactose intolerance, Lapp lactase deficiency (lactose intolerance), glucose-galactose malabsorption (condition marked by inability of the body to absorb glucose and galactose sugars)

Before taking MONOCEF O CV 100/62.5 ORAL SUSPENSION inform your doctor if the child has:

Previous hypersensitivity reactions to cefpodoxime, other cephalosporins, penicillin, and/or other medicines

Interactions

A. Drug-Drug Interactions:

Before administering MONOCEF O CV 100/62.5 ORAL SUSPENSION, inform your doctor, if your child is taking any of the following medicine:

Antacids (medicines used to relieve indigestion and heartburn) Ex. sodium bicarbonate, aluminium hydroxide
Probenecid (used to manage gout)
Nephrotoxic drugs (medicines that can damage kidney via various mechanisms) Ex. aminoglycosides, amphotericin B

Overdosage:

If the child or anyone else accidentally take too much of MONOCEF O CV 100/62.5 ORAL SUSPENSION, consult and inform your doctor immediately or visit the nearby hospital. The symptoms of overdosage of MONOCEF O CV 100/62.5 ORAL SUSPENSION may include nausea, vomiting, epigastric distress, and diarrhoea.

Synopsis

Drug	:	Cefpodoxime, Clavulanic Acid
Pharmacological Category	:	Cephalosporins, Beta-lactamase inhibitors
Therapeutic Indication	:	Mild to moderate infections (caused by susceptible strains of microorganisms) in children
Dosage Forms	:	Tablet, Dispersible Tablet, Dry Syrup, Dry Suspension, Oral Suspension, Suspension, Syrup

More Information

Storage

Keep MONOCEF O CV 100/62.5 ORAL SUSPENSION out of reach of children
Store MONOCEF O CV 100/62.5 ORAL SUSPENSION below 25°C

FAQs About MONOCEF O CV 100/62.5 ORAL SUSPENSION

Q: What is MONOCEF O CV 100/62.5 ORAL SUSPENSION used for?

A: MONOCEF O CV 100/62.5 ORAL SUSPENSION is used in children to manage mild to moderate infections such as otitis media (middle ear infection), nose & throat infections, respiratory tract infection, urinary tract infection, reproductive tract infection, and skin infection.

Q: How MONOCEF O CV 100/62.5 ORAL SUSPENSION works?

A: MONOCEF O CV 100/62.5 ORAL SUSPENSION helps to manage mild to moderate infections, where Cefpodoxime works by managing the formation of the protective covering of the bacteria which is essential for the survival of bacteria and Clavulanic acid works by reducing the resistance and enhancing the activity of Cefpodoxime against bacteria thus managing the occurrence of infections in affected children.

Q: What are the most common side effects of taking MONOCEF O CV 100/62.5 ORAL SUSPENSION?

A: The most common side effects of administering MONOCEF O CV 100/62.5 ORAL SUSPENSION in child are diarrhoea, nausea, vomiting, abdominal pain, headache, vaginal fungal infections, and/or vulvovaginal infections. Consult your doctor if any of these symptoms worsens.

Q: Can MONOCEF O CV 100/62.5 ORAL SUSPENSION cause diarrhoea?

A: Yes, MONOCEF O CV 100/62.5 ORAL SUSPENSION causes diarrhoea as it is the most common side effect associated with the use of medicine. If such side effects experienced, then ask the child to drink lots of fluids such as water or fruit juices so that the child is sufficiently hydrated. Do not administer any medicine to manage the condition on your own. Consult your doctor if the symptom does not improve or becomes worse.

Q: How MONOCEF O CV 100/62.5 ORAL SUSPENSION is administered in the child?

A: Administer MONOCEF O CV 100/62.5 ORAL SUSPENSION in child as advised by your physician. Shake the dry powder loose and reconstitute the dry powder in required ml of water before consuming. Your doctor will decide the exact dose and duration of management for your child depending on child’s age, body weight and disease condition.

References

1. K.D. Tripathi. Beta-Lactam Antibiotics. Essentials of Medical Pharmacology. Seventh Edition. 2013. Page – 724 & 728.

2. P Gehanno, B Barry, S Bobin, C Safran. Twice daily cefpodoxime proxetil compared with thrice daily amoxicillin/clavulanic acid for treatment of acute otitis media in children. NIH National Library of Medicine. National Center for Biotechnology Information. PubMed.gov. [Revised in 1994] [Accessed on 7th July 2022] https://pubmed.ncbi.nlm.nih.gov/7855555/

3. CiplaMed. CEFOPROX CV Tablets. [Revised in October 2018] [Accessed on 7th July 2022] https://ciplamed.com/content/cefoprox-cv-tablets-suspension

4. Leeford Healthcare Limited. CEKODA CV DRY SYRUP. [Accessed on 7th July 2022] https://www.leeford.in/product/375/cekoda-cv-dry-syrup

Useful Diagnostic Tests

Complete Blood Count (CBC)/ Hemogram
Kidney Function Test (KFT)
Peripheral Smear Examination By Pathologist
Serum Electrolytes/ Electrolytes Profile
Culture & Sensitivity, Blood
Healthy Midlife Checkup
Urine Routine & Microscopy
Women Health Checkup - Essential
Full Body Checkup – Gold

Author Details

Written By Dr. N. Sai Swaroop - Pharm.D

Reviewed For Accuracy By Dr. Salem Gill - MBBS

Last updated on 26 Jul 2024 | 11:36 AM(IST)

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