New Revised MRP, 100% GST benefit passed MICAFUNG PLUS 50 Injection 1's
Netmeds First Membership
INTRODUCTION
MICAFUNG PLUS 50 INJECTION contains Micafungin which belongs to the group of medicine called Antifungal agents. It is used to treat systemic fungal infections such as invasive candidiasis. It can also be used in treating fungal infections of the food pipe where treatment with an injection is considered appropriate.
It also helps in preventing fungal infections among patients who have undergone bone-marrow transplantation and in patients who are risk of developing neutropenia (low WBC count in blood).
MICAFUNG PLUS 50 INJECTION should be used under careful medical supervision. Make sure to take the full course of the therapy to achieve better control over infection. Failure or skipping doses in between the therapy may not result in adequate infection control.
Talk to your doctor before receiving MICAFUNG PLUS 50 INJECTION if you have any liver or kidney problems. You must also inform your doctor if have anemia or any other blood related problems as a precaution. MICAFUNG PLUS 50 INJECTION is not recommended for use in breastfeeding women. It should be used in pregnant women only if considered necessary by the physician.
The most common side effects of receiving MICAFUNG PLUS 50 INJECTION are pain and swelling at the site of injection, headache, loss or disturbed taste sensation, tiredness, fever, chills, shortness of breath, diarrhea, stomach pain and high or low blood pressure. Consult your doctor if any of these side effect worsens.
USES OF MICAFUNG PLUS 50 INJECTION
- Treats and prevents fungal infections (both systemic and non-systemic)
HOW MICAFUNG PLUS 50 INJECTION WORKS
MICAFUNG PLUS 50 INJECTION is an antifungal medication. It acts by blocking the actions of certain cellular proteins (beta-glucan) which is essential for the fungal cell to maintain the rigid cell structure. As a result, it makes the fungal cells weak and fragile and eventually destroys them.
DIRECTIONS FOR USE
MICAFUNG PLUS 50 INJECTION will be given to you only by a doctor or a nurse into the vein (intravenously). Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and severity of infection.
SIDE EFFECTS OF MICAFUNG PLUS 50 INJECTION
COMMON
- low RBC, WBC and platelet counts in blood
- low blood potassium, magnesium and calcium levels
- headache
- pain and inflammation at the injection-site
- nausea, vomiting
- diarrhoea, stomach pain
- liver problems, increased levels of bile pigment in the blood
- increased heart rate, high or low blood pressure
- increased blood urea levels
UNCOMMON
- low albumin levels in blood
- increased sweating
- low sodium and phosphate levels in blood
- high blood potassium levels
- anorexia (eating disorder)
- insomnia (trouble sleeping)
- anxiety, confusion
- tiredness, shakiness, dizziness
- loss or disturbed taste sensation
- shortness of breath
- constipation
- jaundice (yellowing of the skin or whites of the eyes)
- problems in bile circulation (cholestasis)
- skin rash, itching and flushing
- kidney problems, edema
Contact your doctor immediately if you experience any of the following side effects after receiving MICAFUNG PLUS 50 INJECTION:
- severe skin reactions (such as widespread skin rash, blistering, peeling or bleeding on any part of the skin with fever, chills, enlarged lymph nodes and malaise or pink or reddish skin lesions on palms or soles)
HOW TO MANAGE SIDE EFFECTS
Application Site Reactions
Place an ice pack on the injected site. Do not move the affected area frequently. If the symptom worsens, consult your doctor.
Constipation
Eat plenty of fiber rich foods such as fresh fruits, vegetables and cereals. Drink plenty of fluids. Exercise more regularly. Consult your doctor if this side effect bothers you.
Dizziness Or Drowsiness
Try to rest and relax. Get enough sleep. Avoid driving or operating any tools or machines completely while you are feeling dizzy. Consult your doctor if your dizziness worsens.
Headache
Rest and relax. Keep yourself hydrated by drinking plenty of fluids such as water or electrolytes. Applying a pain-relieving balm on your forehead can be beneficial. Do not consume excessive alcohol, as it could aggravate your headache. Consult your doctor if your headache worsens.
Nausea And Vomiting
Stick to simple meals and avoid oil rich or spicy foods. Consult your doctor if nausea worsens.
WARNING & PRECAUTIONS
PREGNANCY
Monitoring requiredMICAFUNG PLUS 50 INJECTION is not recommended for use in pregnant women unless considered necessary by the physician. Therefore, consult your doctor before receiving it.
BREASTFEEDING
ContraindicatedMICAFUNG PLUS 50 INJECTION is not recommended for use in breastfeeding women. Therefore, consult your doctor before receiving it.
DRIVING AND USING MACHINES
Use with CautionMICAFUNG PLUS 50 INJECTION is unlikely to affect your ability for driving and using machines. However, it may cause slight dizziness among few people. Therefore, do not drive or operate any heavy tools or machines if your ability is affected by this medicine.
KIDNEY
Use with CautionMICAFUNG PLUS 50 INJECTION should be used with caution in patients with kidney problems. Therefore, inform your doctor before receiving it.
LIVER
Use with CautionMICAFUNG PLUS 50 INJECTION should be used with caution in patients with severe liver problems. Therefore, inform your doctor before receiving it.
ALLERGY
ContraindicatedInform your doctor before receiving MICAFUNG PLUS 50 INJECTION if you are allergic to Micafungin or to any other ingredients of this medicine.
USE IN PEDIATRICS
Use with CautionMICAFUNG PLUS 50 INJECTION should be used with caution in children and adolescents (aged below 18 years). Therefore, consult your doctor before receiving it.
USE IN GERIATRICS
Use with CautionMICAFUNG PLUS 50 INJECTION can be used with caution in elderly patients. Therefore, consult your doctor before receiving it.
OTHERS
Before receiving MICAFUNG PLUS 50 INJECTION, inform your doctor if you:
- have hemolytic anemia (low RBC count in blood)
- have hemolysis (breakdown of RBCs)
INTERACTIONS
A. Drug-Drug Interactions:
Before receiving MICAFUNG PLUS 50 INJECTION, inform your doctor if you are taking any of the following medicines:
- sirolimus (a medicine used to prevent rejection of organ transplant or cause immune system suppression)
- antifungal antibiotics (used for fungal infections) such as Amphotericin B, desoxycholate or itraconazole
- nifedipine (a medicine used to treat high blood pressure)
B. Drug-Food interaction:
No interactions found between MICAFUNG PLUS 50 INJECTION and any food or drinks.
Overdosage:
MICAFUNG PLUS 50 INJECTION will be given to you only by a doctor or nurse in a hospital, and so it is unlikely to receive an overdose. However, if you are worried that you may have been given too much of MICAFUNG PLUS 50 INJECTION, contact your doctor immediately.
SYNOPSIS
| Drug | : | Micafungin |
| Pharmacological Category | : | Echinocandins |
| Therapeutic Indication | : | Fungal infections |
| Dosage Forms | : | Injection |
MORE INFORMATION
- Keep MICAFUNG PLUS 50 INJECTION out of reach of children
- Store MICAFUNG PLUS 50 INJECTION at room temperature
FAQs ABOUT MICAFUNG PLUS 50 INJECTION
Q: What is MICAFUNG PLUS 50 INJECTION used for?
A: MICAFUNG PLUS 50 INJECTION is used to treat systemic fungal infections such as invasive candidiasis. It can also be used in treating fungal infections of the food pipe where treatment with an injection is considered appropriate. It also helps in preventing fungal infections among patients who have undergone bone-marrow transplantation and in patients who are risk of developing neutropenia (low WBC count in blood).
Q: Is MICAFUNG PLUS 50 INJECTION an antibiotic?
A: No. MICAFUNG PLUS 50 INJECTION is an antifungal medicine that acts by making the fungal cells weak and fragile. This helps in destroying them and stopping the further spread of infection.
Q: Does MICAFUNG PLUS 50 INJECTION affect liver?
A: MICAFUNG PLUS 50 INJECTION may unusually cause decreased bile flow, enlarged liver, liver disorder or injury, and jaundice (yellowing of the skin and whites of the eyes). Therefore, caution should be undertaken if you have or ever had any liver problems. Therefore, consult your doctor before receiving it.
Q: What are the side effects of MICAFUNG PLUS 50 INJECTION?
A: The most common side effects of receiving MICAFUNG PLUS 50 INJECTION are pain and swelling at the site of injection, headache, loss or disturbed taste sensation, tiredness, fever, chills, shortness of breath, diarrhea, stomach pain and high or low blood pressure. Consult your doctor if any of these side effect worsens.
Q: Can a person taking MICAFUNG PLUS 50 INJECTION breastfeed?
A: MICAFUNG PLUS 50 INJECTION is not recommended for use in breastfeeding women. Therefore, consult your doctor before receiving it.
Q: How long should I receive MICAFUNG PLUS 50 INJECTION?
A: You need to receive therapy with MICAFUNG PLUS 50 INJECTION for the stipulated duration prescribed by your doctor. Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition.
Q: Is MICAFUNG PLUS 50 INJECTION safe?
A: MICAFUNG PLUS 50 INJECTION is safe at doses prescribed by the physician. Therefore, do not alter the dose of MICAFUNG PLUS 50 INJECTION without consulting your doctor.
Q: Can I stop receiving MICAFUNG PLUS 50 INJECTION without consulting your doctor?
A: No. You should not stop receiving MICAFUNG PLUS 50 INJECTION without consulting your doctor as it may reduce its effectiveness. Therefore, receive MICAFUNG PLUS 50 INJECTION for the stipulated duration recommended by your doctor to achieve maximum results.
REFERENCES
1. KD. Tripathi. Antifungal Drugs. Essentials of Medical Pharmacology. 7th Edition. 2013. Page – 790.
2. Maria Kotsopoulou, Christina Papadaki, Konstantinos Anargyrou, Alexandros Spyridonidis, Ioannis Baltadakis, Helen A. Papadaki, Maria Angelopoulou, Vasiliki Pappa, Kleoniki Liakou, Manto Tzanetakou, Marina Moustaka and George Vassilopoulos. Effectiveness and Safety of Micafungin in Managing Invasive Fungal Infections among Patients in Greece with Hematologic Disorders: The ASPIRE Study. NIH. National Library of Medicine. National Center for Biotechnology Information. PMC. PubMed Central. February 2019. [Accessed on 24th March 2023] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6522581/
3. Flynn Pharma Limited. Micafungin 50 mg and 100mg powder for concentrate for solution for infusion. European Medicines Compendium. [Revised in May 2022]. [Accessed on 24th March 2023] https://www.medicines.org.uk/emc/files/pil.11840.pdf
4. Astellas Pharma US, Inc. MYCAMINE® (micafungin for injection), for intravenous use. U.s Food and Drug Administration. [Revised in July 2020]. [Accessed on 24th March 2023] https://www.astellas.us/docs/mycamine.pdf
USEFUL DIAGNOSTIC TESTS
- Complete Blood Count
AUTHOR DETAILS
Written By Srilekha. R, B.Pharm
Last updated on 24 Mar 2023 | 05:50 PM(IST)