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Introduction About MEZOLAM 7.5MG TABLET
MEZOLAM 7.5MG TABLET contains Midazolam, which belongs to the group of medicines called benzodiazepines (sedatives). MEZOLAM 7.5MG TABLET is used to management of insomnia (inability to sleep) and to produce sleepiness or drowsiness and to relieve anxiety before a medical test or a procedure. MEZOLAM 7.5MG TABLET is also used to manage sudden repetitive attacks of fits (epilepsy).
Epilepsy (fits) is a central nervous system (neurological) disorder which affects the brain creating a disturbance in nerve cells and electrical activity leading to sudden, uncontrolled body movements.
Before taking MEZOLAM 7.5MG TABLET, inform your doctor if you have chronic respiratory problems, myasthenia gravis (muscle weakness), a history of drug abuse or depression, narrow-angle glaucoma, sleep apnoea syndrome (sleep disorder in which breathing stops and starts repeatedly), kidney, heart, liver problems.
MEZOLAM 7.5MG TABLET is generally not recommended during pregnancy especially in the last trimester and breastfeeding, unless deemed necessary. MEZOLAM 7.5MG TABLET should be used with caution in elderly patients, and is contraindicated in children. MEZOLAM 7.5MG TABLET has a few side effects like nausea, vomiting, headache, drowsiness, runny nose, throat irritation, nasal discomfort, and dizziness in some cases. If any of these symptoms worsen, contact your doctor for advice.
Uses Of MEZOLAM 7.5MG TABLET
In adults:
- Manage short-term insomnia (inability to sleep)
- Manage sudden repetitive attacks of fits (epilepsy)
- For procedural sedation
How MEZOLAM 7.5MG TABLET Works
MEZOLAM 7.5MG TABLET contains midazolam which works by increasing a particular chemical messenger in the brain that acts as a natural nerve-calming agent (GABA) resulting in sedative, hypnotic (sleep-inducing), anxiolytic (anti-anxiety), anticonvulsant, and muscle relaxant properties. Hence MEZOLAM 7.5MG TABLET helps manage fits by stabilizing the altered, electrical activity of nerve cells in the brain.
How to use MEZOLAM 7.5MG TABLET
Take MEZOLAM 7.5MG TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending on your age, body weight and disease condition.
Side Effects Of MEZOLAM 7.5MG TABLET
Common
- nausea
- vomiting
- headache
- drowsiness
- runny nose
- throat irritation
- nasal discomfort
Uncommon
- hypersensitivity reactions
- feeling confused
- feeling very happy or excited (euphoria)
- loss of libido
- feeling depressed
- restlessness, agitation, irritability, aggression, delusion, anger, nightmares, hallucinations, psychosis, or inappropriate behaviour
- feeling tired or sleepy or being sedated for a long time
- difficulty co-ordinating muscles
- temporary loss of memory
- seeing double
- stomach upsets
- skin reactions including rash
- muscle weakness
- fatigue
- an increased risk of falling and fractures in the elderly
Rare
Stop taking MEZOLAM 7.5MG TABLET and contact your doctor immediately if you experience any of the following side effects:
- signs of heart attack symptoms like include chest pain
- breathing problems, sometimes causing the breathing to stop
How To Manage Side Effects
Stomach upsets:
Drink lots of fluids and water to keep yourself hydrated. Try to avoid taking any medicine on your own to manage diarrhoea and consult your doctor if the symptom gets worse.
Nasal discomfort:
Try to take steam inhalation. Do not take any other medication without consulting your doctor.
Nausea:
Try to relax and rest. Eat and drink slowly or try to have smaller and more frequent meals. If symptoms do not improve, contact your doctor.
Headache:
Try a cold pack or use a heating pad or hot compress. Ease pressure on your scalp or head. Dim the lights. Hydrate yourself and practice relaxation.
Warning & Precautions
Pregnancy
MEZOLAM 7.5MG TABLET is generally not recommended for use in pregnant women unless considered clearly necessary. Consult your doctor before taking it.
Breastfeeding
MEZOLAM 7.5MG TABLET is generally not recommended for use in breastfeeding women as it may pass through the breast milk. Consult your doctor before taking it.
Driving and Using Machines
Do not drive or operate any machines if you feel dizzy after taking MEZOLAM 7.5MG TABLET.
Alcohol
Do not consume alcohol if you are on MEZOLAM 7.5MG TABLET as this may cause breathing problems.
Kidney
MEZOLAM 7.5MG TABLET should be used with caution in patients with kidney diseases. Consult your doctor before taking MEZOLAM 7.5MG TABLET.
Liver
MEZOLAM 7.5MG TABLET should be used with caution in patients with liver diseases. Consult your doctor before taking MEZOLAM 7.5MG TABLET.
Allergy
Do not take MEZOLAM 7.5MG TABLET if you are allergic to midazolam. Symptoms of Allergic reactions include rashes, swelling, and shortness of breath.
Lungs
MEZOLAM 7.5MG TABLET should be used with caution in patients with respiratory diseases. Consult your doctor before taking MEZOLAM 7.5MG TABLET.
Heart Disease
MEZOLAM 7.5MG TABLET should be used with caution in patients with heart diseases. Consult your doctor before taking MEZOLAM 7.5MG TABLET.
Others
MEZOLAM 7.5MG TABLET is not recommended for use if you:
- are hypersensitive to midazolam
Before taking MEZOLAM 7.5MG TABLET, inform your doctor if you:
- if you regularly take large amounts of alcohol or have had problems with alcohol or drug abuse in the past
- have breathing problems
- have high or low blood pressure
- suffer from mental disorders including depression, psychosis, or schizophrenia
Use in paediatrics:
MEZOLAM 7.5MG TABLET is contraindicated in children and adolescents Consult your doctor before taking it.
Use in geriatrics:
MEZOLAM 7.5MG TABLET should be used with caution in elderly (65years and above) patients. Consult your doctor for advice.
Interactions
A. Drug-Drug interactions:
Before taking MEZOLAM 7.5MG TABLET, inform your doctor if you are taking any of the following medicine:
- medicines for depression (Ex. citalopram)
- hypnotic medicines, to make you sleep (Ex. zopiclone)
- sedatives to make you feel calm or sleepy (Ex. barbiturates, benzodiazepines)
- tranquilliser medicines for anxiety or to help you sleep (Ex. pentobarbital)
- carbamazepine or phenytoin (these may be used for fits or seizures)
- rifampicin to manage tuberculosis
- medicines for HIV called protease inhibitors (Ex. saquinavir)
- antibiotics to manage infection (Ex. erythromycin or clarithromycin)
- medicines to manage fungal infections (Ex. ketoconazole, voriconazole, fluconazole, itraconazole,)
- strong pain killers (Ex. ketorolac)
- antihistamines to manage allergic reactions (Ex. cetirizine)
- any kind of herbal medicine for depression
- medicines for high blood pressure (Ex. diltiazem)
Overdosage:
If you or anyone else accidentally take too much of MEZOLAM 7.5MG TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose may include feeling sick (nausea), vomiting, dizziness, slowing of breathing, drowsiness or coma, slurred speech, loss of balance, and slow reactions.
Synopsis
| Drug | : | Midazolam |
| Pharmacological Category | : | Benzodiazepines |
| Therapeutic Indication | : | Insomnia (inability to sleep), fits or seizure, and relieves anxiety |
| Dosage Forms | : | Tablet, nasal spray, injection, syrup |
More Information
- Keep MEZOLAM 7.5MG TABLET out of reach from children
- Store at room temperature
FAQs About MEZOLAM 7.5MG TABLET
What are the uses of MEZOLAM 7.5MG TABLET?
MEZOLAM 7.5MG TABLET is used in the management of short-term insomnia (inability to sleep), to manage sudden repetitive attacks of fits (epilepsy) and procedural sedation. Conscious sedation is a technique which uses a combination of medicines to help you relax (sedate) and to block pain and reduce anxiety during a medical procedure. You will stay awake but may not be able to speak and is referred to as procedural sedation and analgesia.
How to use MEZOLAM 7.5MG TABLET?
Take MEZOLAM 7.5MG TABLET as advised by your physician. Swallow MEZOLAM 7.5MG TABLET with a glass of water and do not chew or crush the medicine. Your doctor will decide the correct dose for you depending on your age, body weight and disease condition.
Does MEZOLAM 7.5MG TABLET has any side effects?
MEZOLAM 7.5MG TABLET has few side effects like any other medicine. The symptoms include nausea, vomiting, headache, drowsiness, runny nose, throat irritation, and nasal discomfort. If any of these symptoms become worsen, contact your doctor for advice.
Can we use MEZOLAM 7.5MG TABLET for pregnant women?
If you are pregnant or think you may be pregnant or are planning to have a baby, ask your doctor for advice before taking MEZOLAM 7.5MG TABLET. It is generally not recommended during pregnancy and breastfeeding. Consult your doctor for advice.
How does MEZOLAM 7.5MG TABLET work?
MEZOLAM 7.5MG TABLET contains midazolam which works by increasing a particular chemical messenger in the brain that acts as a natural nerve-calming agent (GABA) resulting in sedative, hypnotic (sleep-inducing), anxiolytic (anti-anxiety), anticonvulsant, and muscle relaxant properties. Hence MEZOLAM 7.5MG TABLET helps manage fits by stabilizing the altered, electrical activity of nerve cells in the brain.
References
1. KD Tripathi. Sedative-Hypnotics Essentials of medical pharmacology. seventh edition. 2017. Page – 397-411.
2. Dundee, J.W. Halliday, N.J, Harper, K.W. Midazolam, A Review of its Pharmacological Properties and Therapeutic Use. [Revised in Oct 2012] [Accessed on 29th August 2022] https://doi.org/10.2165/00003495-198428060-00002
3. Roche Products (Pty) Ltd Midazolam. [Revised in Oct 2010] [Accessed on 29th August 2022] https://www.sahpra.org.za/wp-content/uploads/2020/06/Dormicum_PIL_Roche-Products_MCC-Format01-October-2010.pdf
4. F. Hoffmann -La Roche Ltd Midazolam. [Revised in Nov 2017] [Accessed on 29th August 2022] https://www.roche.com.sg/content/dam/rochexx/roche-com-sg/documents/product-page/Dormicum%20Tab%20Nov%202017%20PI.pdf
5. MIMS Midazolam. [Accessed on 29th August 2022] https://www.mims.com/hongkong/drug/info/dormicum/mechanism-of-action
6. Drugs.com Midazolam. [Accessed on 29th August 2022] https://www.drugs.com/monograph/midazolam.html


