Metolar XR 50mg Capsule 15'S

Introduction About METOLAR XR 50MG CAPSULE

Metolar XR 50mg Capsule contains Metoprolol Succinate an active compound classified under Beta-blockers. It is usually included in care plans for individuals looking to manage cardiovascular-related parameters which is high blood pressure, angina pectoris (chest pain), heart failure, arrhythmias or palpitations, heart attacks and migraine headaches). This extended-release capsule provides a steady release over time, which may support consistent heart rhythm control under professional supervision.

METOLAR XR 50MG CAPSULE is usually taken with or immediately after meals. Do not stop taking this medicine without consulting your doctor as a precaution.

Avoid alcohol consumption as it lowers blood pressure. It is not advised for use in patients with asthma, COPD, severe bradycardia, second or third-degree heart block, cardiogenic shock, cardiac failure, sick sinus syndrome (unless a permanent pacemaker is present) and unmanaged pheochromocytoma.

Inform your doctor if you have diabetes, stroke, liver or kidney disease or if you are pregnant or breastfeeding as a precaution.

Low blood pressure, tiredness, dizziness, headache, cold hands and feet are some of the common side effects associated with the use metoprolol. Consult your doctor if they trouble you.

Key Composition

• Active Ingredient: Metoprolol Succinate (50mg)
• Excipients: Cellulose compounds, stabilizers, and release modifiers

Uses Of METOLAR XR 50MG CAPSULE

It is used to manage,

• High blood pressure
• Angina pectoris (chest pain)
• Palpitations
• Heart attack and heart failure
• Migraine 

Benefits of METOLAR XR 50MG CAPSULE

1. Supports Stable Heart Rhythm Throughout the Day

The extended-release format helps maintain a consistent effect over 24 hours, contributing to more stable pulse rate patterns under clinical supervision.

2. Once-Daily Convenience with Prolonged Action

Designed to be taken once a day, it minimizes dosing frequency and offers steady absorption, which may help reduce fluctuations often associated with short-acting versions.

3. Beta-1 Selectivity may reduce unwanted effects

Metolar XR contains Metoprolol Succinate, which acts selectively on beta-1 receptors in the heart. This may reduce the likelihood of respiratory-related concerns when compared to non-selective beta-blockers.

4. Helps in Maintaining Steady Blood Flow and Circulation

By slowing down the heart rate slightly, the capsule supports efficient heart pumping, which can contribute to improved circulatory balance.

5. Favored in Long-Term Cardiovascular Regimens

The slow-release design makes it suitable for long-term usage as per healthcare provider's direction, ensuring consistent heart support over extended periods.

How METOLAR XR 50MG CAPSULE Works

In hypertension, METOLAR XR 50MG CAPSULE works by blocking the effect of adrenaline on the heart and decreasing cardiac output, also reducing the outflow of sympathetic neurons, and suppressing renin activity (normally responsible for the increase in blood pressure). Together, these actions lower blood pressure effectively.

In angina pectoris, METOLAR XR 50MG CAPSULE works by blocking adrenaline effects on the heart and decreases the heart rate, blood pressure, and extent of heart contraction. It also reduces the oxygen requirements of the heart, providing relief from angina.

In heart failure, METOLAR XR 50MG CAPSULE slows down the heart rate and makes it easier for the heart to pump blood around the body.

How to use METOLAR XR 50MG CAPSULE

1. How to take Metolar XR 50mg Capsule?

Metolar XR 50mg Capsule is usually taken once daily, as advised by your doctor. It should be swallowed whole with water, ideally at the same time each day to maintain a steady level of the medicine in the body.

2. Dosage Instructions for Metolar XR

Your doctor will determine the appropriate strength and frequency based on your medical profile. Do not adjust the dosage on your own. The extended-release design ensures a controlled release over 24 hours. Do not crush or chew the capsule.

3. Timing and Food Considerations While Taking Metoprolol XR

Metolar XR should be taken with or immediately after food. Taking it with a meal helps improve absorption and reduces the likelihood of stomach discomfort or lightheadedness. Try to take it at the same time daily, preferably in the morning with breakfast, unless otherwise advised.

Things to Keep in Mind During Daily Use

• Monitor your pulse and blood pressure regularly if recommended

• Avoid alcohol unless approved by your healthcare provider
• Stay well hydrated and avoid sudden posture changes (e.g., standing too fast)
• Inform your doctor about any other medications, including herbal or over-the-counter products

What if I forgot to take METOLAR XR 50MG CAPSULE

• If you forget a dose, take it as soon as you remember
• However, if it is nearly time for the next one, skip the missed dose, do not double up
• Regular timing is important to maintain the capsule’s extended-release effect

Can You Stop Metolar XR Suddenly?

Do not stop Metolar XR suddenly without medical supervision. Stopping abruptly may affect how the heart functions, especially in those with ongoing cardiovascular conditions. Doctors usually advise gradual tapering when needed.

Overdose

If you or anyone else has accidentally taken too much of this medicine, consult your doctor immediately or visit the nearby hospital. Symptoms of overdosage are nausea, vomiting, bluish discolouration of the skin, severe bradycardia, low blood pressure (fatigue, dizziness), atrioventricular block, heart failure, bronchospasm or shortness of breath.

Side Effects Of METOLAR XR 50MG CAPSULE

Common side effects of METOLAR XR 50MG CAPSULE

• feeling faint on standing because of low blood pressure
• tiredness, drowsiness
• cold hands and feet
• dizziness
• headache
• diarrhoea
• constipation
• abdominal pain
• pins and needles
• muscle cramps
• difficulty in sleeping
• shortness of breath
• skin rash

When to Speak to a Healthcare Provider:

• symptoms of an allergic reaction such as skin rash, itching, flushing, swelling of the face, lips, tongue or throat, difficulty in breathing or swallowing

How Metolar XR May affect daily activities

While using Metolar XR 50mg Capsule, some individuals may notice changes in energy levels, alertness, or reaction time, especially during the initial phase. Activities like driving, operating machinery, or climbing stairs should be done cautiously until you understand how the capsule affects you.

Things to watch for during long-term use

If you are on Metolar XR for several weeks or months, your doctor may advise routine checks for:

• Heart rate and blood pressure tracking
• Electrolyte balance (especially potassium or sodium)
• Signs of cold extremities or circulation issues
• Mood, fatigue, or exercise tolerance changes

Does Metolar XR Affect sleep or energy levels?

Some users report fatigue, drowsiness, or sleep disturbances like vivid dreams during use. These effects are generally mild and may improve over time. If they persist, your doctor may evaluate the dosage or suggest lifestyle adjustments.

Is It Safe to Stop Metolar XR Suddenly?

No. Metolar XR should never be stopped abruptly, especially if used over a long duration. Sudden discontinuation can cause unwanted changes in heart rhythm or blood pressure. Your doctor may recommend gradually reducing the dose to allow your body to adjust safely.

Warning & Precautions

Pregnancy

Contraindicated

METOLAR XR 50MG CAPSULE is not recommended for use in pregnant women. Reproductive studies in animals have shown fetotoxicity (e.g., delayed ossification, reduced foetal weight, and embryotoxic effects) when used at high doses. There is limited, controlled data in pregnant women, but some observational studies suggest foetal growth restriction especially when used in the second or third trimester.

Breastfeeding

Contraindicated

Do not use in breastfeeding women, as metoprolol may pass through the breast milk.

Driving and Using Machines

Use with Caution

Do not drive or operate any machines if you feel dizzy and tired after taking this medicine.

Alcohol

Consult your doctor

Alcohol consumption to be avoided  while taking this medicine as it will make you feel dizzier.

Kidney

Use with Caution

METOLAR XR 50MG CAPSULE should be used with caution in patients with kidney diseases.

Liver

Use with Caution

METOLAR XR 50MG CAPSULE should be used cautiously in patients with liver diseases.

Allergy

Contraindicated

Do not take METOLAR XR 50MG CAPSULE if you are allergic to Metoprolol or any other ingredients in this medicine.

Lungs

Contraindicated

METOLAR XR 50MG CAPSULE is not recommended for use in patients with bronchospastic diseases like asthma or COPD.

Heart Disease

Consult your doctor

METOLAR XR 50MG CAPSULE is not advised in patients with severe bradycardia, low blood pressure, second or third-degree heart block, cardiogenic shock, decompensated cardiac failure, or sick sinus syndrome (unless a permanent pacemaker is present) and should be used with caution in patients with 1st-degree heart block, myocardial infarction, angina pectoris, heart failure, diseases of the heart valve, or enlarged heart muscle.

Use In Pediatrics

Contraindicated

The use of metoprolol is not recommended as there is limited data on the use of metoprolol in children and adolescents.

Use In Geriatrics

Use with Caution

This medicine should be used with caution in elderly patients aged 65 years or above.

Other Warnings for METOLAR XR 50MG CAPSULE

Before taking this medicine, inform your doctor if you have:

• major surgery or anaesthesia
• stroke
• diabetes or low blood sugar
• hyperthyroidism
• peripheral vascular disease
• psoriasis

Who should not take [GBNKEYWORD

METOLAR XR 50MG CAPSULE is not recommended for use if you have:

• severe peripheral arterial disease
• metabolic acidosis
• unmanaged phaeochromocytoma

Diet and Lifestyle Advice

1. Maintain a Heart-Healthy Eating Pattern

While using Metolar XR, following a balanced diet can support overall cardiovascular health:

• Limit sodium (salt) intake to help regulate blood pressure
• Include high-Fiber foods like oats, brown rice, and leafy vegetables
• Opt for lean proteins such as fish, legumes, and skinless poultry
• Choose healthy fats like olive oil, nuts, and seeds in moderation
• Stay hydrated with water-based fluids, unless otherwise advised

2. Physical Activity: Consistency Over Intensity

Gentle, regular physical activity is generally encouraged, unless restricted by a doctor:

• Walking, swimming, or yoga may support circulation and reduce stress
• Avoid sudden intense workouts, especially at the beginning of medication use
• Always warm up and cool down to avoid dizziness or sudden pulse drops

3. Minimize Alcohol and Smoking

• Alcohol may enhance the blood pressure lowering effect, leading to dizziness
• Tobacco can counteract the benefits of beta-blockers on the heart and blood vessels

4. Daily Routine Tips While Taking Metolar XR

• Take the capsule at the same time daily, preferably with food
• Avoid skipping meals, as this may affect energy and pulse
• Use a pill organizer or phone reminder to support daily consistency
• Get enough restful sleep, as fatigue may occur initially

5. Stress Management and Mental Wellness

Long-term use of Metolar XR may benefit from integrated mental wellness support:

• Practice deep breathing, mindfulness, or guided meditation
• Stay socially connected and avoid isolation
• Address mood changes with a professional if they persist

Drug - Drug interaction

1. Medicines that may enhance the Effect of Metolar XR

• Calcium channel blockers (e.g., Verapamil, Diltiazem)
• Antiarrhythmics (e.g., Amiodarone, Propafenone)
• Clonidine (especially during discontinuation)
• Digoxin – may enhance bradycardia or AV block when combined

2. Medicines that may reduce the effect of Metolar XR

These may blunt the blood pressure-lowering or heart rate–reducing effect:

• Nonsteroidal anti-inflammatory drugs (NSAIDs) – e.g., Ibuprofen, Diclofenac
• Rifampicin – a strong liver enzyme inducer
• Certain antidepressants (e.g., Fluoxetine, Paroxetine – may interfere with metabolism)

3. Medicines that may increase metoprolol levels in blood

These drugs inhibit the enzymes responsible for breaking down Metoprolol, increasing its levels:

• Cimetidine (acid reducer)
• SSRIs like Paroxetine, Sertraline
• Hydralazine (may impair clearance and raise blood levels)

4. Anti-Diabetic Medicines

• Metoprolol may mask signs of low blood sugar (e.g., tremors, rapid heartbeat) caused by medications like Insulin or Sulfonylureas (e.g., Glimepiride)

5. Interaction with Anaesthesia and Surgery Medications

• General anaesthetics may increase the cardiac depressant effect of Metoprolol

6. Other Notable Drug Interactions

• Ergot alkaloids – may worsen blood vessel constriction
• Monoamine oxidase inhibitors (MAOIs) – may dangerously enhance blood pressure-lowering effect

Synopsis

More Information

Did You Know?

• Metolar XR 50mg contains Metoprolol Succinate, which is an extended-release formulation. This means the medication is released slowly over 24 hours, helping maintain more stable levels in the body, potentially reducing heart rate fluctuations across the day
• Metoprolol Succinate is a beta-1 selective blocker, meaning it primarily affects heart-related beta receptors and not those in the lungs. This selectivity is an important consideration in people with respiratory sensitivities
• Taking Metolar XR with food, preferably the same meal every day, may improve its absorption and reduce side effects like dizziness or fatigue
• Crushing or chewing the capsule destroys its extended-release mechanism, leading to a sudden release of the medicine. That is why it should always be swallowed whole with water.

Pharmacist’s Insight

Metolar XR 50mg offers a long-acting release of Metoprolol, which is commonly part of heart rate control regimens. Patients on this capsule are often monitored for blood pressure and pulse regularly. It should be used only under medical supervision and not be stopped suddenly without professional advice.

Why Choose Metolar XR 50mg Capsule?

• Extended-release format for steady absorption
• Prescribed widely for heart rate and rhythm
• Available in once-daily format for ease of use
• May reduce the need for multiple daily dosages

FAQs About METOLAR XR 50MG CAPSULE

References

1. K D Tripathi. Cardiovascular drugs. Essentials of medical pharmacology. Seventh edition. 2013. Page - 523, 545, 564.

2. Bethesda (MD). Metoprolol. National Institute of Health. NLM. National Centre for Biotechnology Information. PubMed, 2006. [Accessed on 28th June 2025] 

3. Aralez Pharmaceuticals US Inc. Metoprolol. [Revised in December 2016] [Accessed on 28th June 2025] 

4. Dr Reddy’s Laboratories Limited. Metoprolol. [Revised in April 2016] [Accessed on 28th June 2025] 

5. STADA Arzneimittel AG. Metoprolol. [Accessed on 28th June 2025] 

User Feedback

Useful Diagnostic Tests

• Kidney function test (KFT)
• Cardiac Risk Profile

Author Details

Written By Dr. Janet.C - Pharm.D

Reviewed For Accuracy By Dr. Thamada Manikanta Praveen - MBBS, MD (General Medicine)

Last updated on 28 Jun 2025 | 04:47 PM(IST)