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Introduction About MESALACURE 1.2GM TABLET
MESALACURE 1.2GM TABLET contains Mesalamine, an anti-inflammatory drug used to manage ulcerative colitis and Crohn's disease. It helps reduce inflammation in the intestines and provides long-term relief.
Take MESALACURE 1.2GM TABLET once daily after meals as directed by your doctor. Your doctor may decide the correct dose depending on your age, body weight and health condition. For adults and elderly patients, a maximum of 4.8g per day is recommended. Patients with kidney problems and liver problems must take this medicine with caution. Careful monitoring of liver and kidney functions, regular health checkups and dose adjustments are required in such patients.
While taking MESALACURE 1.2GM TABLET long-term to prevent remission of disease, it is important to closely follow the health advice suggested by your doctor, undergo regular kidney function tests, and never skip doses, to get better control over flare-ups.
MESALACURE 1.2GM TABLET should be used in pregnant only if considered necessary by the physician. Clinical studies have demonstrated that higher doses of mesalamine can harm the growing baby. Hence, your doctor will decide whether you should take this medicine or not if you are pregnant.
Mesalamine can pass through breast milk and can cause stomach upset in nursing infant. Hence, MESALACURE 1.2GM TABLET should be discontinued or used with extreme caution in breastfeeding women.
The most common side effects of taking MESALACURE 1.2GM TABLET are nausea, bloating, indigestion, stomach irritation or upset, headache, dizziness or tiredness. Consult your doctor if any of these symptom trouble you.
Seek immediate medical attention, if you experience severe stomah pain with bloody stools, skin reactions, trouble in passing urine or have severe nausea and vomiting with stomach discomfort.
Uses Of MESALACURE 1.2GM TABLET
It is used in the management of inflammatory bowel diseases such as:
- Ulcerative colitis
- Crohn’s disease
Who Should Take MESALACURE 1.2GM TABLET?
- Patients with mild to moderate ulcerative colitis – Helps reduce inflammation and manage symptoms like diarrhea and rectal bleeding.
- Individuals needing maintenance therapy – Reduces flare-ups and maintains remission in ulcerative colitis.
- People with inflammatory bowel disease (IBD) – Helps control chronic inflammation in the colon.
- Those prescribed by a doctor for long-term bowel health – Supports gut health and prevents disease progression.
- Patients without salicylate allergy or severe kidney/liver disease – Should be used cautiously in individuals with pre-existing conditions.
Benefits of MESALACURE 1.2GM TABLET
MESALACURE 1.2GM TABLET for ulcerative colitis:
- Reduces inflammation in the colon, relieving symptoms like diarrhea, rectal bleeding, and abdominal pain.
- Promotes healing of the intestinal lining, improving overall gut health and preventing complications.
MESALACURE 1.2GM TABLET for Crohn’s disease:
- Helps control mild to moderate inflammation in the intestines, reducing discomfort and flare-ups.
- Aids in symptom relief, such as diarrhea and abdominal pain, improving quality of life.
MESALACURE 1.2GM TABLET for Maintaining Remission in Ulcerative Colitis:
- Reduces recurrence of symptoms by keeping inflammation under control.
- Supports long-term bowel health, reducing the need for stronger medications or surgery.
How to use MESALACURE 1.2GM TABLET
Take MESALACURE 1.2GM TABLET exactly as prescribed by your doctor. Consistent daily intake at the same time is recommended to maintain effective drug levels.
How to Take MESALACURE 1.2GM TABLET:
- Usually, it is taken once daily with food to prevent stomach upset.
- Swallow the tablet whole with water; do not crush or chew it.
- Maintain adequate fluid intake during therapy to support kidney function.
MESALACURE 1.2GM TABLET – Recommended Dosage For Adults:
- Induction of Remission: For active, mild to moderate ulcerative colitis, the typical dosage is 2.4g to 4.8g taken once daily. Clinical studies have shown that doses up to 4.8g per day are effective in inducing remission.
- Maintenance of Remission: To maintain remission, a lower dose as prescribed by your doctor may be sufficient.
MESALACURE 1.2GM TABLET Dosage for Children:
The safety and effectiveness of MESALACURE 1.2GM TABLET in pediatric patients have not been established. Use in children should only occur if prescribed by a qualified healthcare professional, with dosage adjustments based on the child's weight and clinical condition.
MESALACURE 1.2GM TABLET Dose Adjustments for Liver and Kidney Patients:
- Kidney Impairment: Mesalamine is known to be substantially excreted by the kidneys. Patients with impaired renal function should use MESALACURE 1.2GM TABLET with caution, and renal function should be evaluated prior to and during therapy.
- LiverImpairment: Caution is advised when administering MESALACURE 1.2GM TABLET to patients with liver disease. Monitoring liver function tests may be necessary.
MESALACURE 1.2GM TABLET Maximum Daily Dosage?
The maximum recommended daily dose for adults is 4.8g. Exceeding this dose may increase the risk of adverse effects and is not advised unless under strict medical supervision.
Can I stop taking MESALACURE 1.2GM TABLET suddenly?
Do not abruptly discontinue MESALACURE 1.2GM TABLET without consulting your doctor, as sudden cessation may lead to a relapse of symptoms. If discontinuation is necessary, your doctor will provide a tapering schedule appropriate for your condition.
What to Expect After Taking MESALACURE 1.2GM TABLET?
- Symptom Improvement: Patients may notice a reduction in symptoms such as diarrhea, rectal bleeding, and abdominal pain within a few weeks of starting therapy.
- Maintenance of Remission: Continued use as prescribed helps maintain remission and prevent flare-ups of ulcerative colitis.
What if I forgot to take MESALACURE 1.2GM TABLET
If you miss a dose, take it as soon as you remember. If it's near the time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not take two doses at once to make up for a missed dose.
Overdose
- Symptoms: Overdose may lead to symptoms such as nausea, vomiting, stomach pain, dizziness, or, in severe cases, renal impairment.
- Action: In case of suspected overdose, seek immediate medical attention. Supportive measures and symptomatic treatment should be initiated promptly.
Side Effects Of MESALACURE 1.2GM TABLET
Like all medicine, MESALACURE 1.2GM TABLET may cause certain side effects in some individuals, although not everybody gets them,
Common Side Effects of MESALACURE 1.2GM TABLET are:
- Nausea
- Headache
- Diarrhea
- Abdominal pain, indigestion
- Sleepiness or Dizziness
- Tiredness, Fatigue
Can MESALACURE 1.2GM TABLET Cause Kidney Problems?
- Yes, MESALACURE 1.2GM TABLET (mesalamine) may cause kidney problems, including interstitial nephritis (kidney inflammation), which can lead to reduced kidney function over time.
- Patients with pre-existing renal impairment should use MESALACURE 1.2GM TABLET with caution, and regular kidney function tests (serum creatinine levels) are recommended during therapy.
Does MESALACURE 1.2GM TABLET Affect Liver Function?
- In rare cases, MESALACURE 1.2GM TABLET can cause elevated liver enzymes, indicating potential liver irritation or damage.
- Patients with liver disease should use this medication cautiously and undergo regular liver function tests to monitor any adverse effects.
Is MESALACURE 1.2GM TABLET Safe for Long-Term Use?
- Yes, MESALACURE 1.2GM TABLET is commonly used for long-term maintenance therapy in ulcerative colitis to prevent flare-ups and maintain remission.
- However, long-term use requires regular kidney and liver function monitoring to detect any potential side effects early.
Can MESALACURE 1.2GM TABLET Cause Hair Loss?
- Hair loss (alopecia) has been reported in some patients taking MESALACURE 1.2GM TABLET, though it is a rare side effect.
- This side effect is usually temporary and may improve after stopping or adjusting the medication.
Does MESALACURE 1.2GM TABLET Affect Fertility?
- There is limited evidence suggesting that MESALACURE 1.2GM TABLET significantly affects male or female fertility.
- Some studies indicate that mesalamine may reduce sperm motility in men, but this effect is usually reversible after discontinuation.
Can MESALACURE 1.2GM TABLET Cause Joint Pain or Muscle Pain?
- Yes, joint pain (arthralgia) and muscle pain (myalgia) have been reported as side effects of MESALACURE 1.2GM TABLET.
- These symptoms are typically mild but may require medical attention if persistent or severe.
How Long Do MESALACURE 1.2GM TABLET Side Effects Last?
- Mild side effects (e.g., nausea, headache, stomach discomfort) usually resolve within a few days to weeks as the body adjusts to the medication.
- Serious side effects (e.g., kidney or liver issues) may persist and require discontinuation or medical intervention.
- If side effects do not subside or worsen, consult your doctor for alternative treatment options.
When To Seek Medical Attention?
Stop taking MESALACURE 1.2GM TABLET and consult your doctor immediately in case if you experience:
- serious skin reactions such as Stevens-Johnson syndrome, toxic epidermal necrolysis associated with symptoms such as reddish non-elevated, target-like/circular patches on the trunk associated with central blisters, skin peeling, ulcers of eyes, nose, mouth, throat, and/or genitals.
- signs of acute intolerance syndrome such as cramping, severe stomach pain, bloody & excessive stools (diarrhoea), fever, headache, and/or rash.
- unexplained bruising (without injury), rash, anaemia, fever, sore throat, and/or unusual bleeding
- signs of allergic reaction such as swelling of tongue, lips/eyes
- signs of increased pressure in brain such as headache, blurred/dimmed vision, double vision, brief/permanent vision loss, dizziness, nausea, vomiting, and/or ringing in ears
Warning & Precautions
Pregnancy
Consult your doctorPregnant women should use MESALACURE 1.2GM TABLET only if prescribed by a doctor, with regular monitoring. Studies have not shown significant birth defects, but high doses may increase the risk of complications such as preterm birth. Therefore, MESALACURE 1.2GM TABLET should be used in pregnant women only if the benefits overweigh the risks.
Breastfeeding
Consult your doctorStudies have shown that mesalamine passes into breast milk, but the amount is usually low. Some breastfed infants have experienced diarrhea or irritability, so monitoring the baby’s reaction is essential. If adverse effects occur in the infant, consult your doctor about alternative treatments or adjusting the dose.
Driving and Using Machines
Use with CautionMESALACURE 1.2GM TABLET may cause dizziness and sleepiness in some individuals. Therefore, do not drive or perform tasks that require complete alterness.
Alcohol
Consult your doctor- Avoid or limit alcohol while taking MESALACURE 1.2GM TABLET, as it may increase the risk of stomach irritation and liver toxicity.
- Alcohol can also worsen side effects like nausea, dizziness, and dehydration.
- Chronic alcohol use may strain kidney and liver function, which are already monitored during MESALACURE 1.2GM TABLET treatment.
- If you consume alcohol, consult your doctor to assess potential risks based on your condition.
Kidney
Consult your doctorAvoid MESALACURE 1.2GM TABLET if you have severe kidney disease. It should be used with extreme caution in patients with mild to moderate kidney problems. Kidney disease patients must periodically check their kidney function as suggested by their doctor to protect from unpleasant side effects. Dose adjustments and careful monitoring are required in such patients
Liver
Consult your doctorMESALACURE 1.2GM TABLET is not recommended for use in patients with severe liver problems. It should be used with caution in patients who have/had mild to moderate liver disease. Therefore, inform your doctor before taking MESALACURE 1.2GM TABLET, if you have any pre-existing liver conditions so that your doctor can adjust the dose and carefully monitor your health during the therapy duration.
Allergy
ContraindicatedDo not take MESALACURE 1.2GM TABLET if you are allergic to Mesalamine, salicylates, sulfasalazine, and/or any other ingredients of this medicine.
Lungs
Use with CautionMESALACURE 1.2GM TABLET should be used with caution in patients with lung problems. Therefore, inform your doctor before taking MESALACURE 1.2GM TABLET if you have lung problems as a precaution.
Heart Disease
Use with CautionMESALACURE 1.2GM TABLET should be used with caution in patients with heart problems such as inflammation of heart (due to infection). Consult your doctor before taking MESALACURE 1.2GM TABLET.
Use In Pediatrics
ContraindicatedMESALACURE 1.2GM TABLET is not recommended for use in children and adolescents (aged below 18 years) due to lack of data on safety and efficacy of the medicine. Consult your doctor before administering the medicine to the child.
Use In Geriatrics
Use with CautionMESALACURE 1.2GM TABLET should be used with caution in elderly patients (aged above 65 years) especially in patients with kidney or liver problems and when consumed in long-term.
Other Warnings for MESALACURE 1.2GM TABLET
Before taking MESALACURE 1.2GM TABLET inform your doctor if you:
- have narrowing/blockage of stomach/gut
Safety Advice
Expert Tips To Follow While Taking MESALACURE 1.2GM TABLET:
- Taking MESALACURE 1.2GM TABLET with meals helps improve absorption and reduces stomach discomfort.
- Drink plenty of water to prevent kidney-related side effects and maintain overall hydration.
- Regular kidney (serum creatinine) and liver function tests are recommended during long-term use.
- Alcohol can worsen stomach irritation and liver toxicity, so it’s best to avoid or limit consumption.
- Stopping MESALACURE 1.2GM TABLET suddenly may cause a relapse of ulcerative colitis symptoms. Always consult your doctor before discontinuing.
- Inform your doctor if you are pregnant or breastfeeding, as dosage adjustments may be needed.
- Avoid taking iron supplements or antacids at the same time as MESALACURE 1.2GM TABLET to prevent absorption issues. Maintain a 2-hour gap if necessary.
- Seek medical advice if you experience severe abdominal pain, blood in stools, yellowing of the skin, or kidney-related symptoms like reduced urine output.
Diet and Lifestyle Advice
|
Foods to Eat |
Foods to Avoid |
|
Low-fiber fruits (bananas, melons) |
High-fiber fruits (raw apples, berries) |
|
Well-cooked vegetables (carrots, pumpkin) |
Raw vegetables, cruciferous veggies (broccoli, cauliflower) |
|
Lean proteins (chicken, fish, tofu) |
Red meat, processed meats |
|
White rice, white bread, oats |
Whole grains (brown rice, whole wheat, quinoa) |
|
Lactose-free dairy, plant-based milk |
Full-fat dairy (milk, cheese, cream) |
|
Healthy fats (olive oil, avocado) |
Fried and greasy foods |
|
Herbal teas, water, electrolyte drinks |
Alcohol, caffeinated drinks, carbonated sodas |
Can I Drink Alcohol While Taking [GBNKEYWORD]?
- Alcohol can irritate the digestive tract and worsen inflammation, making ulcerative colitis symptoms worse.
- Combining alcohol with MESALACURE 1.2GM TABLET increases the risk of liver toxicity and gastrointestinal discomfort.
- Smoking may worsen IBD symptoms and reduce the effectiveness of treatment.
- It is best to avoid alcohol and smoking while on MESALACURE 1.2GM TABLET for better disease management.
MESALACURE 1.2GM TABLET & Weight Gain/Loss – Impact on Metabolism
- MESALACURE 1.2GM TABLET does not directly cause weight gain or loss, but changes in diet due to ulcerative colitis can affect weight.
- Possible weight loss:
- Reduced nutrient absorption due to inflammation.
- Appetite loss during flare-ups.
- Possible weight gain:
- Increased appetite during remission.
- Reduced physical activity due to fatigue.
- Maintaining a balanced diet and regular exercise can help manage weight effectively.
Stress Management & Ulcerative Colitis
Meditation & Deep Breathing: Reduces anxiety and promotes relaxation.
Regular Exercise: Low-impact activities like yoga and walking help improve gut health.
Adequate Sleep: Helps the body recover and manage inflammation.
Therapy & Support Groups: Talking to others with IBD can provide emotional support.
Managing stress effectively can help improve overall quality of life and reduce ulcerative colitis flare-ups.
MESALACURE 1.2GM TABLET vs Mesacol 400mg vs. Budez CR
|
Feature |
MESALACURE 1.2GM TABLET |
Mesacol 400mg |
Budez CR |
|
Active Ingredient |
Mesalamine (1.2g) |
Mesalamine (400mg) |
Budesonide (3mg) |
|
Mode of Action |
Anti-inflammatory effect on colon lining |
Anti-inflammatory effect on colon lining |
Suppresses immune response & inflammation |
|
Indication |
Ulcerative colitis (mild to moderate) Crohn’s disease, |
Ulcerative colitis (mild to moderate) Crohn’s disease |
Crohn’s disease, Ulcerative colitis (moderate to severe) |
|
Release Mechanism |
Extended-release for once-daily dosing |
Delayed-release to overcome gastric acid irritation |
Controlled-release for localized steroid action |
|
Dosage Frequency |
Once daily |
2-3 times daily |
Once daily |
|
Side Effects |
Mild GI discomfort, headache |
Mild GI discomfort, headache |
Increased risk of infections, adrenal suppression |
|
Long-Term Use |
Safe for maintenance therapy |
Safe for maintenance therapy |
Not recommended for long-term use due to steroid effects |
|
Best For |
Patients preferring once-daily dosing |
Patients who need multiple doses |
Patients with moderate to severe inflammation not responding to 5-ASA |
Drug - Drug interaction
Before taking MESALACURE 1.2GM TABLET, inform your doctor if you are taking any of the following medicine:
- sulphasalazine (medicine used to manage ulcerative colitis)
- non- steroidal anti-inflammatory drugs (medicines used to reduce fever and provide relief from pain) Ex. aspirin, ibuprofen, diclofenac
- azathioprine (used after transplantations or to manage autoimmune diseases)
- mercaptopurine (medicines used to manage leukemia)
- medicines used to manage blood clotting (Ex. warfarin)
Drug - Food interaction
High-Fat Meals
- May delay absorption of MESALACURE 1.2GM TABLET, potentially affecting its effectiveness.
- It is recommended to take the tablet with a normal meal rather than a high-fat meal.
Dairy Products
- No major interaction, but some patients report stomach discomfort when taken with milk.
- If you experience bloating or discomfort, take it with water instead.
Caffeine and Carbonated Drinks
- May worsen gastrointestinal irritation in sensitive individuals.
- Limiting excessive caffeine or soda may help reduce stomach-related side effects.
Alcohol
- Increases the risk of stomach irritation and liver toxicity.
- Can worsen dizziness, nausea, and dehydration when taken with MESALACURE 1.2GM TABLET.
Grapefruit Juice
- Although no direct interaction is established, grapefruit juice can affect drug metabolism and should be consumed in moderation.
For best results, follow a balanced diet and take MESALACURE 1.2GM TABLET as directed by your doctor to avoid potential food-related interactions.
Synopsis
|
Drug |
: |
Mesalamine |
|
Pharmacological Category |
: |
Salicylates |
|
Therapeutic Indication |
: |
Ulcerative colitis |
|
Dosage Forms |
: |
Tablets, Oral disintegrating tablets, Suppositories, Sachet, Granules, Powder, Pellet, Enema |
More Information
How to Stop or Switch from MESALACURE 1.2GM TABLET:
1. Do Not Stop Abruptly
- Stopping MESALACURE 1.2GM TABLET suddenly can trigger a relapse of ulcerative colitis symptoms.
- Always consult your doctor before discontinuing or switching medications.
2. Tapering the Dose (If Required)
- Depending on your condition, your doctor may gradually reduce the dose instead of stopping it suddenly.
- A slow taper allows your body to adjust and prevent flare-ups.
3. Switching to Another Medication
- If your doctor prescribes a different medication (e.g., MESALACURE 1.2GM TABLET, Budez CR, or biologics), they will guide you on how to transition.
- Some patients may need overlapping therapy for a smooth switch.
4. Monitoring for Symptoms
- After stopping or switching, watch for signs of relapse like diarrhea, abdominal pain, or blood in stools.
- If symptoms return, inform your doctor immediately.
5. Lifestyle and Diet Adjustments
- Follow a low-inflammatory diet, stay hydrated, and manage stress to reduce flare-ups after stopping MESALACURE 1.2GM TABLET.
Always follow medical advice when stopping or switching MESALACURE 1.2GM TABLET to avoid complications and ensure long-term remission.
Relevant Health Articles
Crohn’s Disease: Here’s What You Should Eat And Avoid To Treat This Inflammatory Disorder
Ayurveda For Ulcerative Colitis: Effective Natural Remedies To Treat This Inflammatory Disease
Gut Health: 5 Must-To-Add Supplements For Optimal Digestive Functions And Overall Well-being
FAQs About MESALACURE 1.2GM TABLET
Q: What is MESALACURE 1.2GM TABLET used for?
A: MESALACURE 1.2GM TABLET is used for the management of inflammatory bowel disease such as ulcerative colitis and Crohn’s disease. It helps reduce inflammation in the colon, control symptoms like diarrhea, abdominal pain, and rectal bleeding, and maintain remission in ulcerative colitis.
Q: How does MESALACURE 1.2GM TABLET help in ulcerative colitis?
A: MESALACURE 1.2GM TABLET contains mesalamine (5-aminosalicylic acid or 5-ASA), which has anti-inflammatory properties. It targets inflammation in the colon lining, reduces flare-ups, and promotes healing in patients with ulcerative colitis.
Q: Can MESALACURE 1.2GM TABLET be used for Crohn’s disease?
A: MESALACURE 1.2GM TABLET is primarily prescribed for ulcerative colitis, but in some cases, it may be used to manage mild-to-moderate Crohn’s disease affecting the colon. However, other medications like Budesonide or biologics may be preferred for Crohn’s treatment.
Q: How long should I take MESALACURE 1.2GM TABLET?
A: The duration of MESALACURE 1.2GM TABLET treatment depends on the severity of ulcerative colitis. Some patients may need it short-term for flare-ups, while others take it long-term to prevent relapses and maintain remission. Always follow your doctor’s advice.
Q: What is the best time to take MESALACURE 1.2GM TABLET?
A: MESALACURE 1.2GM TABLET is usually taken once daily, preferably at the same time each day for maximum effectiveness. Some doctors recommend taking it in the morning with food to improve absorption.
Q: Can MESALACURE 1.2GM TABLET be taken daily?
A: Yes, MESALACURE 1.2GM TABLET is a long-term maintenance therapy for ulcerative colitis. Taking it daily as prescribed helps in reducing inflammation, reducing flare-ups, and maintaining remission.
Q: Should MESALACURE 1.2GM TABLET be taken before or after food?
A: MESALACURE 1.2GM TABLET is usually taken with or after food to reduce the risk of stomach irritation and improve drug absorption. Always follow the dosage instructions provided by your doctor.
Q: Can I stop taking MESALACURE 1.2GM TABLET suddenly?
A: No, stopping MESALACURE 1.2GM TABLET suddenly can trigger a relapse of ulcerative colitis symptoms. Your doctor may gradually reduce the dose if stopping is necessary to prevent withdrawal effects.
Q: How long does MESALACURE 1.2GM TABLET take to show effects?
A: MESALACURE 1.2GM TABLET starts working within a few days to weeks. Most patients notice symptom improvement within 2 to 4 weeks, but full benefits may take several months.
Q: What are the benefits of MESALACURE 1.2GM TABLET for ulcerative colitis?
A: MESALACURE 1.2GM TABLET reduces inflammation and promotes healing in the colon lining. It also prevents ulcerative colitis flare-ups and helps maintain long-term remission.
Q: How does MESALACURE 1.2GM TABLET reduce inflammation in the intestines?
A: MESALACURE 1.2GM TABLET works by blocking inflammatory chemicals (prostaglandins and leukotrienes) in the colon, thereby reducing swelling, irritation, and tissue damage in ulcerative colitis.
Q: Does MESALACURE 1.2GM TABLET help in maintaining remission?
A: Yes, MESALACURE 1.2GM TABLET is commonly prescribed for long-term maintenance therapy to keep ulcerative colitis in remission and prevent flare-ups.
Q: Can MESALACURE 1.2GM TABLET prevent flare-ups of ulcerative colitis?
A: Yes, taking MESALACURE 1.2GM TABLET regularly as prescribed can reduce the frequency and severity of ulcerative colitis flare-ups, helping patients lead a symptom-free life.
Q: Is MESALACURE 1.2GM TABLET safe for long-term use?
A: Yes, MESALACURE 1.2GM TABLET is generally safe for long-term use, but regular kidney and liver function monitoring is recommended to prevent potential side effects.
Q: Does MESALACURE 1.2GM TABLET improve quality of life for IBD patients?
A: Yes, MESALACURE 1.2GM TABLET reduces symptoms, prevents relapses, and improves bowel health, significantly enhancing the quality of life for ulcerative colitis and IBD patients.
Q: Is MESALACURE 1.2GM TABLET effective for long-term ulcerative colitis treatment?
A: Yes, MESALACURE 1.2GM TABLET is clinically proven to be effective in maintaining remission, reducing inflammation, and preventing ulcerative colitis relapses over long-term use.
Q: How many MESALACURE 1.2GM TABLETs should I take in a day?
A: The usual dosage for adults is 1.2g (one tablet) once daily, but the dosage may vary based on disease severity and doctor’s recommendation.
Q: What is the correct way to take MESALACURE 1.2GM TABLET?
A: Swallow MESALACURE 1.2GM TABLETs whole with water, without crushing or chewing, as it is an extended-release tablet designed for slow drug release in the colon.
Q: How long should I take MESALACURE 1.2GM TABLET for ulcerative colitis?
A: You may need to take MESALACURE 1.2GM TABLET for several months or years depending on your condition. Your doctor will decide the best duration for your treatment.
Q: Can I take MESALACURE 1.2GM TABLET at night?
A: Yes, MESALACURE 1.2GM TABLET can be taken at night, but it is best to take it at the same time daily for consistent drug levels in the body.
Q: What is the maximum dosage of MESALACURE 1.2GM TABLET per day?
A: The maximum recommended daily dose of MESALACURE 1.2GM TABLET is 4.8g (4 tablets per day), divided as per your doctor’s instructions.
Q: Can the MESALACURE 1.2GM TABLET dosage be reduced over time?
A: Yes, once ulcerative colitis is under control, your doctor may gradually reduce the dosage to maintain remission with the lowest effective dose.
Q: What is the dosage of MESALACURE 1.2GM TABLET for elderly patients?
A: Elderly patients may require dose adjustments based on kidney and liver function. A lower starting dose may be recommended to minimize side effects.
Q: Is MESALACURE 1.2GM TABLET dosage different for children and adults?
A: Yes, the dosage is adjusted based on the child’s weight and disease severity. Pediatric doses are lower than adult doses and should be prescribed by a doctor.
Q: Can MESALACURE 1.2GM TABLET be taken during pregnancy?
A: MESALACURE 1.2GM TABLET should be used by pregnant women only if considered necessary by the physician. Certain clinical studies have shown that higher doses of mesalamine causes harm to the growing baby. Your doctor will decide whether you should use this medicine or not after analysing risks and benefits.
Q: How is the MESALACURE 1.2GM TABLET dosage adjusted for kidney or liver issues?
A: Patients with kidney or liver disease may require dose adjustments or regular monitoring to prevent toxicity. Always inform your doctor of any pre-existing conditions.
Q: Does MESALACURE 1.2GM TABLET cause diarrhea?
A: Yes, diarrhea is a possible side effect, but it is usually mild. If it persists or worsens, consult your doctor for dose adjustments.
Q: Can MESALACURE 1.2GM TABLET cause weight gain?
A: MESALACURE 1.2GM TABLET does not directly cause weight gain, but patients may experience weight fluctuations due to changes in appetite, diet, and disease activity.
Q: Does MESALACURE 1.2GM TABLET interact with antibiotics or painkillers?
A: Yes, MESALACURE 1.2GM TABLET may interact with certain antibiotics (ciprofloxacin, metronidazole) and NSAIDs (ibuprofen, aspirin), increasing the risk of gastric irritation and kidney issues.
Q: Can I take MESALACURE 1.2GM TABLET with dairy products?
A: Yes, MESALACURE 1.2GM TABLET can be taken with dairy products, but some patients with lactose intolerance or IBD sensitivity may need to avoid milk-based foods.
References
- Mesalamine Package insert. Sun Pharmaceuticals. Dailymed. National Library of Medicine. [Revised in December 2023]. [Accessed on 26th July 2025].

- Mesalamine. Medlineplus. [Updated in February 2024]. [Accessed on 26th July 2025].

- Mesalamine. NIH. National Library of Medicine. StatPearls. [Updated in February 2024]. [Accessed on 26th July 2025].

- Mesalamine Delayed Release Capsule. U.S. Food and Drug Administration. [Accessed on 26th July 2025].

- Lifestyle, Diet in Inflammatory Bowel Disease. Mayoclinic. [Revised in February 2022]. [Accessed on 26th July 2025].

- Mesalamine. Reviews and Ratings. Drugs.com. [Accessed on 26th July 2025].

- Mesalamine PR Tablets 1.2gm. Central Drugs Standard Control Organisation (CDSCO). March 2009. [Accessed on 26th July 2025].







